- 2021
- Published
Evidence for shared genetics between physical activity, sedentary behaviour and adiposity-related traits
Schnurr, T. M., Stallknecht, Bente Merete, Sørensen, Thorkild I.A., Kilpeläinen, Tuomas O. & Hansen, Torben, 2021, In: Obesity Reviews. 22, 4, 12 p., e13182.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Explaining deep neural networks for knowledge discovery in electrocardiogram analysis
Hicks, S. A., Isaksen, Jonas L., Thambawita, V., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Strümke, I., Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., von Holstein-Rathlou, Niels-Henrik, Halvorsen, P., Maleckar, M. M., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 11 p., 10949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer
Thibord, F., Song, C., Pattee, J., Rodriguez, B. A. T., Chen, M-H., O'Donnell, C. J., Kleber, M. E., Delgado, G. E., Guo, X., Yao, J., Taylor, K. D., Ozel, A. B., Brody, J. A., McKnight, B., Gyorgy, B., Simonsick, E., Leonard, H. L., Carrasquilla, G. D., Guindo-Martinez, M., Silveira, A. & 30 others, , 2021, In: Journal of Thrombosis and Haemostasis. 19, 8, p. 2019-2028Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting plasma GLP-1 associates with overweight/obesity and cardiometabolic risk factors in children and adolescents
Stinson, Sara, Jonsson, Anna Elisabet, Lund, M. A. V., Frithioff-Bøjsøe, C., Holm, L. A., Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 6, p. 1718-1727Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fecal microbiota transplantation in hepatic encephalopathy: a systematic review
Madsen, M., Kimer, N., Bendtsen, Flemming & Petersen, Andreas Munk, 2021, In: Scandinavian Journal of Gastroenterology. 56, 5, p. 560-569 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fish oil replacement prevents, while docosahexaenoic acid-derived protectin DX mitigates end-stage-renal-disease in atherosclerotic diabetic mice
Perazza, L. R., Mitchell, P. L., Lizotte, F., Jensen, Benjamin Anderschou Holbech, St-Pierre, P., Trottier, J., Barbier, O., Mathieu, P., Geraldes, P. M. & Marette, A., 2021, In: FASEB Journal. 35, 5, 18 p., 21559.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis
Larsen, I. S., Jensen, Benjamin Anderschou Holbech, Bonazzi, E., Choi, Beatrice So-Yun, Kristensen, N. N., Schmidt, E. G. W., Süenderhauf, A., Morin, L., Olsen, P. B., Hansen, L. B. S., Schröder, T., Sina, C., Chassaing, B. & Marette, A., 2021, In: Gut Microbes. 13, 1, 20 p., 1988836.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic markers of abdominal obesity and weight loss after gastric bypass surgery
Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Grarup, Niels, Burgdorf, Kristoffer Sølvsten, drb459, drb459, Pedersen, Oluf Borbye, Ängquist, Lars, Fenger, M., Sørensen, Thorkild I.A., Madsbad, Sten & Hansen, Torben, 2021, In: PLoS ONE. 16, 5, 11 p., 0252525.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity
Deshmukh, H. A., Madsen, A. L., Viñuela, A., Have, C. T., Grarup, N., Tura, A., Mahajan, A., Heggie, A. J., Koivula, R. W., De Masi, F., Tsirigos, K. K., Linneberg, A., Drivsholm, T., Pedersen, O., Sørensen, T. I. A., Astrup, A., Gjesing, A. A. P., Pavo, I., Wood, A. R., Ruetten, H. & 14 others, , 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. 80-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis
Galatà, G., García-Montero, A. C., Kristensen, T., Dawoud, A. A. Z., Muñoz-González, J. I., Meggendorfer, M., Guglielmelli, P., Hoade, Y., Alvarez-Twose, I., Gieger, C., Strauch, K., Ferrucci, L., Tanaka, T., Bandinelli, S., Schnurr, T. M., Haferlach, T., Broesby-Olsen, S., Vestergaard, H., Møller, M. B., Bindslev-Jensen, C. & 7 others, , 2021, In: American Journal of Human Genetics. 108, 2, p. 284-294 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test
Jonsson, Anna Elisabet, Stinson, Sara, Torekov, Signe Sørensen, Clausen, Tine Dalsgaard, Færch, K., Kelstrup, Louise, Grarup, Niels, Mathiesen, Elisabeth, Damm, Peter, Witte, D. R., Jørgensen, M. E., Pedersen, Oluf Borbye, Holst, Jens Juul & Hansen, Torben, 2021, In: BMC Medical Genomics. 14, 7 p., 3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., Bretherick, A. D., Richardson, T. G., Klughammer, J., Iotchkova, V., Sharp, G., Al Khleifat, A., Shatunov, A., Iacoangeli, A., McArdle, W. L., Ho, K. M. & 31 others, , 2021, In: Nature Genetics. 53, 9, p. 1311-1321 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation
Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice
Borchers, N., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: European Respiratory Journal. 58, Suppl. 65, 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Milk Oligosaccharides Modulate Fecal Microbiota and Are Safe for Use in Children With Overweight: A Randomized Controlled Trial
Fonvig, Cilius Esmann, Amundsen, I. D., Vigsnæs, L. K., Sørensen, N., Frithioff-Bojsoe, C., Christiansen, M., Hedley, P. L., Holm, L. A., McConnell, B. & Holm, Jens-Christian, 2021, In: Journal of Pediatric Gastroenterology and Nutrition. 73, 3, p. 408-414 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health
Brial, F., Chilloux, J., Nielsen, T., Vieira-Silva, S., Falony, G., Andrikopoulos, P., Olanipekun, M., Hoyles, L., Djouadi, F., Neves, A. L., Rodriguez-Martinez, A., Mouawad, G. I., Pons, N., Forslund, S., Le-chatelier, E., Le Lay, A., Nicholson, J., Hansen, T., Hyotylainen, T., Clement, K. & 7 others, , 2021, In: Gut. 70, 11, p. 2105-2114 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
Pinkerton, J. W., Kim, R. Y., Koeninger, L., Armbruster, N. S., Hansbro, N. G., Brown, A. C., Jayaraman, R., Shen, S., Malek, N., Cooper, M. A., Nordkild, P., Horvat, J. C., Jensen, Benjamin Anderschou Holbech, Wehkamp, J. & Hansbro, P. M., 2021, In: Clinical and Experimental Allergy. 51, 1, p. 120-131 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, , 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model
Borchers, N. S., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: Frontiers in Immunology. 12, 12 p., 636061.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality
Blond, K., Carslake, D., Gjærde, L. K., Vistisen, D., Sørensen, Thorkild I.A., Smith, G. D. & Baker, J. L., 2021, In: Scientific Reports. 11, 1, 10 p., 22408.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance genetic risk score and burden of coronary artery disease in patients referred for coronary angiography
Skals, R., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, Steen, Hansen, Torben, Grarup, Niels, Lee, C. J., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2021, In: PLoS ONE. 16, 6, 11 p., 0252855.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies
Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale association analyses identify host factors influencing human gut microbiome composition
Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, , 2021, In: Nature Genetics. 53, p. 156-165 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism
Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, , 2021, In: Nature Communications. 12, 19 p., 1093.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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