Obesity is associated with vitamin D deficiency in Danish children and adolescents

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Obesity is associated with vitamin D deficiency in Danish children and adolescents. / Plesner, Johanne Lind; Dahl, Maria; Fonvig, Cilius Esmann; Nielsen, Tenna Ruest Haarmark; Kloppenborg, Julie Tonsgaard; Pedersen, Oluf; Hansen, Torben; Holm, Jens-Christian.

In: Journal of Pediatric Endocrinology and Metabolism, Vol. 31, No. 1, 26.01.2018, p. 53-61.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Plesner, JL, Dahl, M, Fonvig, CE, Nielsen, TRH, Kloppenborg, JT, Pedersen, O, Hansen, T & Holm, J-C 2018, 'Obesity is associated with vitamin D deficiency in Danish children and adolescents', Journal of Pediatric Endocrinology and Metabolism, vol. 31, no. 1, pp. 53-61. https://doi.org/10.1515/jpem-2017-0246

APA

Plesner, J. L., Dahl, M., Fonvig, C. E., Nielsen, T. R. H., Kloppenborg, J. T., Pedersen, O., Hansen, T., & Holm, J-C. (2018). Obesity is associated with vitamin D deficiency in Danish children and adolescents. Journal of Pediatric Endocrinology and Metabolism, 31(1), 53-61. https://doi.org/10.1515/jpem-2017-0246

Vancouver

Plesner JL, Dahl M, Fonvig CE, Nielsen TRH, Kloppenborg JT, Pedersen O et al. Obesity is associated with vitamin D deficiency in Danish children and adolescents. Journal of Pediatric Endocrinology and Metabolism. 2018 Jan 26;31(1):53-61. https://doi.org/10.1515/jpem-2017-0246

Author

Plesner, Johanne Lind ; Dahl, Maria ; Fonvig, Cilius Esmann ; Nielsen, Tenna Ruest Haarmark ; Kloppenborg, Julie Tonsgaard ; Pedersen, Oluf ; Hansen, Torben ; Holm, Jens-Christian. / Obesity is associated with vitamin D deficiency in Danish children and adolescents. In: Journal of Pediatric Endocrinology and Metabolism. 2018 ; Vol. 31, No. 1. pp. 53-61.

Bibtex

@article{92c4ae0327e54becbf667bae2101c9c8,
title = "Obesity is associated with vitamin D deficiency in Danish children and adolescents",
abstract = "BACKGROUND: Sufficient serum concentrations of vitamin D are required to maintain bone health during growth. The aims of this study were to determine whether vitamin D deficiency is more prevalent among children and adolescents with obesity compared to their normal weight peers and to identify clinical and biochemical variables associated with vitamin D deficiency.METHODS: One thousand four hundred and eighty-four children and adolescents with overweight/obesity and 2143 population-based controls were recruited from the Danish Childhood Obesity Biobank. Anthropometric variables and fasting concentrations of serum 25-hydroxy vitamin D (25-OH-D), plasma parathyroid hormone (PTH), calcium and phosphate were assessed at baseline. Vitamin D deficiency was defined as serum 25-OH-D concentrations <30 nmol/L. Linear and logistic regressions were used to identify variables associated with vitamin D deficiency.RESULTS: A total of 16.5% of the children and adolescents with obesity (body mass index [BMI] standard deviation score [SDS]>2.33) exhibited vitamin D deficiency, with an odds ratio (OR) 3.41 (confidence interval [CI]: 2.27-5.71; p<0.0001) for being vitamin D deficient compared to their normal weight peers. BMI-SDS was independently and inversely associated with serum 25-OH-D concentrations. Other independent risk factors for vitamin D deficiency were being older than 14 years (OR: 2.39; CI: 1.28-4.48; p=0.006), more than 4 daily hours of screen time (OR: 4.56; CI: 2.59-8.05; p<0.0001) and blood sample assessment during winter-spring (OR: 6.44; CI: 4.47-9.26; p<0.0001).CONCLUSIONS: Vitamin D deficiency was common among Danish children and adolescents with obesity. The degree of obesity was independently associated with lower serum 25-OH-D concentrations.",
author = "Plesner, {Johanne Lind} and Maria Dahl and Fonvig, {Cilius Esmann} and Nielsen, {Tenna Ruest Haarmark} and Kloppenborg, {Julie Tonsgaard} and Oluf Pedersen and Torben Hansen and Jens-Christian Holm",
year = "2018",
month = jan,
day = "26",
doi = "10.1515/jpem-2017-0246",
language = "English",
volume = "31",
pages = "53--61",
journal = "Journal of Pediatric Endocrinology and Metabolism",
issn = "0334-018X",
publisher = "Walterde Gruyter GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Obesity is associated with vitamin D deficiency in Danish children and adolescents

AU - Plesner, Johanne Lind

AU - Dahl, Maria

AU - Fonvig, Cilius Esmann

AU - Nielsen, Tenna Ruest Haarmark

AU - Kloppenborg, Julie Tonsgaard

AU - Pedersen, Oluf

AU - Hansen, Torben

AU - Holm, Jens-Christian

PY - 2018/1/26

Y1 - 2018/1/26

N2 - BACKGROUND: Sufficient serum concentrations of vitamin D are required to maintain bone health during growth. The aims of this study were to determine whether vitamin D deficiency is more prevalent among children and adolescents with obesity compared to their normal weight peers and to identify clinical and biochemical variables associated with vitamin D deficiency.METHODS: One thousand four hundred and eighty-four children and adolescents with overweight/obesity and 2143 population-based controls were recruited from the Danish Childhood Obesity Biobank. Anthropometric variables and fasting concentrations of serum 25-hydroxy vitamin D (25-OH-D), plasma parathyroid hormone (PTH), calcium and phosphate were assessed at baseline. Vitamin D deficiency was defined as serum 25-OH-D concentrations <30 nmol/L. Linear and logistic regressions were used to identify variables associated with vitamin D deficiency.RESULTS: A total of 16.5% of the children and adolescents with obesity (body mass index [BMI] standard deviation score [SDS]>2.33) exhibited vitamin D deficiency, with an odds ratio (OR) 3.41 (confidence interval [CI]: 2.27-5.71; p<0.0001) for being vitamin D deficient compared to their normal weight peers. BMI-SDS was independently and inversely associated with serum 25-OH-D concentrations. Other independent risk factors for vitamin D deficiency were being older than 14 years (OR: 2.39; CI: 1.28-4.48; p=0.006), more than 4 daily hours of screen time (OR: 4.56; CI: 2.59-8.05; p<0.0001) and blood sample assessment during winter-spring (OR: 6.44; CI: 4.47-9.26; p<0.0001).CONCLUSIONS: Vitamin D deficiency was common among Danish children and adolescents with obesity. The degree of obesity was independently associated with lower serum 25-OH-D concentrations.

AB - BACKGROUND: Sufficient serum concentrations of vitamin D are required to maintain bone health during growth. The aims of this study were to determine whether vitamin D deficiency is more prevalent among children and adolescents with obesity compared to their normal weight peers and to identify clinical and biochemical variables associated with vitamin D deficiency.METHODS: One thousand four hundred and eighty-four children and adolescents with overweight/obesity and 2143 population-based controls were recruited from the Danish Childhood Obesity Biobank. Anthropometric variables and fasting concentrations of serum 25-hydroxy vitamin D (25-OH-D), plasma parathyroid hormone (PTH), calcium and phosphate were assessed at baseline. Vitamin D deficiency was defined as serum 25-OH-D concentrations <30 nmol/L. Linear and logistic regressions were used to identify variables associated with vitamin D deficiency.RESULTS: A total of 16.5% of the children and adolescents with obesity (body mass index [BMI] standard deviation score [SDS]>2.33) exhibited vitamin D deficiency, with an odds ratio (OR) 3.41 (confidence interval [CI]: 2.27-5.71; p<0.0001) for being vitamin D deficient compared to their normal weight peers. BMI-SDS was independently and inversely associated with serum 25-OH-D concentrations. Other independent risk factors for vitamin D deficiency were being older than 14 years (OR: 2.39; CI: 1.28-4.48; p=0.006), more than 4 daily hours of screen time (OR: 4.56; CI: 2.59-8.05; p<0.0001) and blood sample assessment during winter-spring (OR: 6.44; CI: 4.47-9.26; p<0.0001).CONCLUSIONS: Vitamin D deficiency was common among Danish children and adolescents with obesity. The degree of obesity was independently associated with lower serum 25-OH-D concentrations.

U2 - 10.1515/jpem-2017-0246

DO - 10.1515/jpem-2017-0246

M3 - Journal article

C2 - 29197860

VL - 31

SP - 53

EP - 61

JO - Journal of Pediatric Endocrinology and Metabolism

JF - Journal of Pediatric Endocrinology and Metabolism

SN - 0334-018X

IS - 1

ER -

ID: 198663404