Juul Holst Group

  1. Published

    Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates

    Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, S. B., Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans

    Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, Rune Ehrenreich, Holst, Jens Juul, Rehfeld, Jens Frederik & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

    Vestergaard, E. T., Hjelholt, A. J., Kuhre, Rune Ehrenreich, Møller, N., Larraufie, P., Gribble, F. M., Reimann, F., Jessen, N., Holst, Jens Juul & Jørgensen, J. O. L., 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2581-2592

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

    Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, Hulot, J., Lewinter, C., Pedersen, H. K., Quinquis, B., Rouault, C., Roume, H., Salem, J., Søndertoft, N. B., Touch, S., Dumas, M., Ehrlich, S. D., Galan, P., Gøtze, J. P., Hansen, Torben, Holst, Jens Juul, Køber, Lars Valeur, Letunic, I., Nielsen, J., Oppert, J., Stumvoll, M., Vestergaard, H., Zucker, J., Bork, P., Pedersen, Oluf Borbye, Bäckhed, F., Clément, K., Raes, J. & MetaCardis Consortium, M. C., 2020, In: Nature. 581, 7808, p. 310-315

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery

    Visentin, R., Brodersen, K., Richelsen, B., Møller, N., Dalla Man, C., Pedersen, A. K., Abrahamsen, J., Holst, Jens Juul & Nielsen, M. F., 2023, In: Journal of Diabetes Research. 2023, 14 p., 127426.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print
  7. Published

    Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings

    Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects

    Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state

    Wever, M. C. M., van Meer, F., Charbonnier, L., Crabtree, D. R., Buosi, W., Giannopoulou, A., Androutsos, O., Johnstone, A. M., Manios, Y., Meek, C. L., Holst, Jens Juul, Smeets, P. A. M. & Full4Health consortium, F. C., 2021, In: NeuroImage. 240, 11 p., 118374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Inability of Some Commercial Assays to Measure Suppression of Glucagon Secretion

    Albrechtsen, Nicolai Jacob Wewer, Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2016, In: Journal of Diabetes Research. 2016, 5 p., 8352957.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

    Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men

    Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, Bolette, Carr, R. D., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Goetze, Jens P. & Plomgaard, Peter Stendahl, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 9, p. 3868-3876

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

    Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    100 years of glucagon and 100 more

    Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cherrington, A. D., Finan, B., Gluud, Lise Lotte, Dean, E. D., Campbell, J. E., Bloom, S. R., Tan, T. M., Knop, Filip Krag & Müller, T. D., 2023, In: Diabetologia. 66, p. 1378–1394

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The liver-alpha cell axis and type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, Filip Krag & Holst, Jens Juul, 2019, In: Endocrine Reviews. 40, 5, p. 1353-1366

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

    Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

    Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia

    Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.

    Research output: Contribution to journalConference abstract in journalResearch

  23. E-pub ahead of print
  24. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model

    Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.

    Research output: Contribution to journalJournal articleResearchpeer-review