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Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease: comparison with peptide YY
Schmidt, P. T., Ljung, T., Hartmann, Bolette, Hare, K. J., Holst, Jens Juul & Hellström, P. M., Feb 2005, In: European journal of gastroenterology & hepatology. 17, 2, p. 207-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture
Holst, Jens Juul, 2021, In: Diabetes. 70, 11, p. 2468-2475 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists
Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, , 2023, medRxiv, 35 p.Research output: Working paper › Preprint › Research
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Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet
Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.Research output: Contribution to journal › Journal article › Research › peer-review
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Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice
Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine
Christensen, L. W., Kuhre, Rune Ehrenreich, Janus, C., Svendsen, B. & Holst, Jens Juul, 17 Sep 2015, In: Physiological Reports. 3, 9, p. 1-13 13 p., e122551.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Voices: Insulin and beyond
Roth, J., Ashcroft, F. M., Wollheim, C. B., Kieffer, T. J., Cherrington, A. D., Bergman, R. N., Taylor, R., Najjar, S. M., Pedersen, Oluf Borbye, Ellingsgaard, H., Holst, Jens Juul, Nauck, M. A., Kadowaki, T., Czech, M. P., Corvera, S., Saltiel, A. R., Corkey, B. E. & Atkinson, M. A., 2021, In: Cell Metabolism. 33, 4, p. 692-699 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Volume of ropivacaine 0.2% and common peroneal nerve block duration: a randomised, double-blind cohort trial in healthy volunteers
Christiansen, Charlotte Bayer, Madsen, M. H., Rothe, C., Andreasen, A. M., Lundstrøm, L. H. & Lange, Kai, 2018, In: Anaesthesia. 73, 11, p. 1361-1367 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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Glucagon-like peptide 1 (GLP-1)
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Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
Effects of 3 months of 10-h per-day time-restricted eating and 3 months of follow-up on bodyweight and cardiometabolic health in Danish individuals at high risk of type 2 diabetes: the RESET single-centre, parallel, superiority, open-label, randomised controlled trial
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Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test
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