- 2022
- Published
Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression
Billeschou, Anna, Johansen, C. D., Christensen, J. B., Kjeldsen, Sasha Alexandra Sampson, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Serizawa, R., Hornum, Mads, Porrini, E., Pedersen, Jens, Ørskov, Cathrine, Gluud, Lise Lotte, Sorensen, Charlotte Mehlin, Holst, Jens Juul, Albrechtsen, Reidar & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Communications Biology . 5, 1, 13 p., 1278.Research output: Contribution to journal › Journal article › Research › peer-review
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Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial
Klausen, M. K., Jensen, M. E., Møller, M., le Dous, N., Jensen, A-M. Ø., Zeeman, V. A., Johannsen, C-F., Lee, A. M., Thomsen, G. K., Macoveanu, J., Fisher, P. M., Gillum, M. P., Jørgensen, N. R., Bergmann, M. L., Enghusen Poulsen, H., Becker, U., Holst, J. J., Benveniste, H., Volkow, N. D., Vollstädt-Klein, S. & 5 others, , 2022, In: JCI insight. 19, 20 p., e159863.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment
Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Sandsdal, Rasmus Michael, Olsen, L. M., Andresen, A., Borg, S. A., Jacobsen, I. C., Finlayson, G., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2022, In: Nature Communications. 13, 1, 11 p., 4770.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice
Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme duration exercise affects old and younger men differently
Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, , 2022, In: Acta Physiologica. 235, 3, e13816.Research output: Contribution to journal › Journal article › Research › peer-review
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Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic men
Canfora, E. E., Hermes, G. D. A., Mueller, M., Bastings, J., Vaughan, E. E., van den Berg, M. A., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2022, In: Gut Microbes. 14, 1Research output: Contribution to journal › Journal article › Research › peer-review
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Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial
Dicks, L., Jakobs, L., Sari, M., Hambitzer, R., Ludwig, N., Simon, M., Stehle, P., Stoffel-Wagner, B., Helfrich, H., Ahlborn, J., Rühl, M., Hartmann, Bolette, Holst, Jens Juul & Ellinger, S., 2022, In: European Journal of Nutrition. 61, p. 687–701Research output: Contribution to journal › Journal article › Research › peer-review
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Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight
Svane, M. S., Johannesen, H. H., Hansen, Adam Espe, Martinussen, C., Bojsen-Møller, K. N., Hansen, M. L., Deacon, Carolyn F., Keller, S. H., Klausen, Thomas Levin, Loft, A., Kjær, Andreas, Löfgren, J., Madsbad, Sten, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: International Journal of Obesity. 46, 11, p. 2058–2062 8 p.Research output: Contribution to journal › Letter › Research › peer-review
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GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274Research output: Contribution to journal › Journal article › Research › peer-review
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GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment
Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 - Incretin and pleiotropic hormone with pharmacotherapy potential. Increasing secretion of endogenous GLP-1 for diabetes and obesity therapy
Holst, Jens Juul, Jepsen, Sara Lind & Modvig, Ida Marie, 2022, In: Current Opinion in Pharmacology. 63, p. 1-7 102189.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 effect on ß-cell function varies according to diabetes remission status after RYGB
Shah, A., Prasad, M., Mark, V., Holst, Jens Juul & Laferrère, B., 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2081-2089Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake
Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal Hormones and β-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial (Oseberg)
Fatima, F., Hjelmesæth, J., Birkeland, K. I., Hanne, G. L., Hertel, J. K., Svanevik, M., Sandbu, R., Småstuen, M. C., Hartmann, Bolette, Holst, Jens Juul & Hofsø, D., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. e756-e766 11 p., dgab643.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon Clearance is Preserved in Type 2 Diabetes
Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon and other proglucagon-derived peptides in the pathogenesis of obesity
Holst, Jens Juul, 2022, In: Frontiers in Nutrition. 9, 8 p., 964406.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1): are its roles as endogenous hormone and therapeutic wizard congruent?
Holst, Jens Juul, 2022, In: Journal of Internal Medicine. 291, 5, p. 557-573Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice
Dal, Jenna Elizabeth Hunt, Holst, Jens Juul & Jepsen, Sara Lind, 2022, In: Frontiers in Endocrinology. 13, 10 p., 884501.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial
Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice
Boer, G. A., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Sparre-Ulrich, A. H., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4486-4499Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglucagonemia in pediatric adiposity associates with cardiometabolic risk factors but not hyperglycemia
Stinson, Sara, Jonsson, Anna Elisabet, Alzola, I. F. D. R., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Holm, L. A., Fonvig, Cilius Esmann, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 6, p. 1569–1576Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoglycaemia and rebound hyperglycaemia increase left ventricular systolic function in patients with type 1 diabetes
Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Lauritsen, J. V., Jørgensen, P. G., Engberg, S., Faber, Jens, Hartmann, Bolette, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2027-2037Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of polymorphism in the β₂-receptor gene on metabolic responses to repeated hypoglycaemia in healthy humans
Rokamp, K. Z., Holst, Jens Juul, Olsen, N. V., Dela, Flemming, Secher, Niels H., Juul, Anders, Faber, Jens, Wiberg, S., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 8, p. e3194–e3205 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism
Belda, E., Voland, L., Tremaroli, V., Falony, G., Adriouch, S., Assmann, K. E., Prifiti, E., Aron-Wisnewsky, J., Debedat, J., Le Roy, T., Nielsen, T., Amouyal, C., Andre, S., Andreelli, F., Blueher, M., Chakaroun, R., Chilloux, J., Coelho, L. P., Dao, M. C., Das, P. & 42 others, , 2022, In: Gut. 71, 12, p. 2463-2480 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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686
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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Glucagon-like peptide 1 (GLP-1)
Research output: Contribution to journal › Review › Research › peer-review
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Latest publications
Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
Effects of 3 months of 10-h per-day time-restricted eating and 3 months of follow-up on bodyweight and cardiometabolic health in Danish individuals at high risk of type 2 diabetes: the RESET single-centre, parallel, superiority, open-label, randomised controlled trial
Research output: Contribution to journal › Journal article › Research › peer-review
Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test
Research output: Contribution to journal › Journal article › Research › peer-review