Kilpeläinen Group

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  1. Published

    Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

    LifeLines Cohort Study, L. C. S., 2021, In: Human Genetics and Genomics Advances. 2, 1, 12 p., 100013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Multi-ancestry Genome-wide Meta-analysis Accounting for Gene-education Interactions in Up to 227,850 Individuals Identifies Several Novel Lipid Loci

    Sung, Y. J., Schwander, K. L., Bentley, A. R., de Vries, P. S., Kilpeläinen, Tuomas O., Noordam, R., Musani, S. K., Aschard, H., de las Fuentes, L. & CHARGE Gene-Lifestyle Interactions, C. G. I., 2019, In: Genetic Epidemiology. 43, 7, p. 912-912 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Methods in Bioarchaeology: What’s New in Profiling an Individual Inside and Out

    Freiwald, C., Belanich, Jonathan Robert & Rand, A., 2022, The Routledge Handbook of Mesoamerican Bioarchaeology. Tieslar, V. (ed.). Routledge, p. 577-600 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  4. Published

    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, Esko, T., Kilpeläinen, Tuomas O., Kutalik, Z., Li, S., Monda, K. L., Dixon, A. L., Holmes, C. C., Kaplan, L. M., Liang, L., Min, J. L., Moffatt, M. F., Molony, C., Nicholson, G., Schadt, E. E., Zondervan, K. T., Feitosa, M. F., Ferreira, T., Allen, H. L., Weyant, R. J., Wheeler, E., Wood, A. R., Estrada, K., Goddard, M. E., Lettre, G., Mangino, M., Gjesing, A. P., Witte, D. R., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Mendelian randomization suggests a causal effect of abdominal obesity on postprandial lipemia

    Christiansen, Malene Revsbech, Hansen, Torben, Sørensen, Thorkild I.A., Grarup, Niels, García Ureña, Mario, Borisevich, D., Oppert, J., Martinez Hernandez, J. A., Blaak, E. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 184 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  6. Published

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and obesity

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, (bioRxiv).

    Research output: Working paper › Research

  7. Published

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: eLife. 11, 25 p., e70386.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

    Zheng, Y., Huang, T., Wang, T., Mei, Z., Sun, Z., Zhang, T., Ellervik, C., Chai, J-F., Sim, X., van Dam, R. M., Tai, E-S., Koh, W-P., Dorajoo, R., Saw, S-M., Sabanayagam, C., Wong, T. Y., Gupta, P., Rossing, P., Ahluwalia, T. S., Vinding, R. K. & 98 others, Bisgaard, H., Bønnelykke, Klaus, Wang, Y., Graff, M., Voortman, T., van Rooij, F. J. A., Hofman, A., van Heemst, D., Noordam, R., Estampador, A. C., V Varga, Tibor, Enzenbach, C., Scholz, M., Thiery, J., Burkhardt, R., Orho-Melander, M., Schulz, C., Ericson, U., Sonestedt, E., Kubo, M., Akiyama, M., Zhou, A., Kilpeläinen, Tuomas O., Hansen, Torben, Kleber, M. E., Delgado, G., McCarthy, M., Lemaitre, R. N., Felix, J. F., Jaddoe, V. W. V., Wu, Y., Mohlke, K. L., Lehtimäki, T., Wang, C. A., Pennell, C. E., Schunkert, H., Kessler, T., Zeng, L., Willenborg, C., Peters, A., Lieb, W., Grote, V., Rzehak, P., Koletzko, B., Erdmann, J., Munz, M., Wu, T., He, M., Yu, C., Lecoeur, C., Froguel, P., Corella, D., Moreno, L. A., Lai, C., Pitkänen, N., Boreham, C. A., Ridker, P. M., Rosendaal, F. R., de Mutsert, R., Power, C., Paternoster, L., Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Djousse, L., Rivadeneira, F., Lee, N. R., Raitakari, O. T., Kähönen, M., Viikari, J., Langhendries, J., Escribano, J., Verduci, E., Dedoussis, G., König, I., Balkau, B., Coltell, O., Dallongeville, J., Meirhaeghe, A., Amouyel, P., Gottrand, F., Pahkala, K., Niinikoski, H., Hyppönen, E., März, W., Mackey, D. A., Gruszfeld, D., Tucker, K. L., Fumeron, F., Estruch, R., Ordovas, J. M., Arnett, D. K., Mook-Kanamori, D. O., Mozaffarian, D., Psaty, B. M., North, K. E., Chasman, D. I. & Qi, L., 2020, In: European Journal of Epidemiology. 35, p. 685–697 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Meal timing of dietary total antioxidant capacity and its association with all-cause, CVD and cancer mortality: the US national health and nutrition examination survey, 1999–2018

    Wang, P., Jiang, Xuye, Tan, Q., Du, S. & Shi, D., 2023, In: International Journal of Behavioral Nutrition and Physical Activity. 20, 13 p., 83.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk

    Leppanen, M. H., Haapala, E. A., Vaisto, J., Ekelund, U., Brage, S., Kilpeläinen, Tuomas O. & Lakka, T. A., 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 1, p. 255-266

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Longitudinal Associations of Fitness, Motor Competence, and Adiposity with Cognition

    Haapala, E. A., Lintu, N., Vaisto, J., Tompuri, T., Soininen, S., Viitasalo, A., Eloranta, A., Venalainen, T., Saakslahti, A., Laitinen, T. & Lakka, T. A., 2019, In: Medicine and Science in Sports and Exercise. 51, 3, p. 465-471

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Increase in adiposity from childhood to adulthood predicts a metabolically obese phenotype in normal-weight adults

    Viitasalo, A., Pitkänen, N., Pahkala, K., Lehtimäki, T., Viikari, J. S. A., Raitakari, O. & Kilpeläinen, Tuomas O., 2020, In: International Journal of Obesity. 44, p. 848-851

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    In vivo characterization of the ultrapotent monoacylglycerol lipase inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048)

    Aaltonen, N., Kedzierska, E., Orzelska-Górka, J., Lehtonen, M., Navia-Paldanius, D., Jakupovic, Hermina, Savinainen, J. R., Nevalainen, T., Laitinen, J. T., Parkkari, T. & Gynther, M., Oct 2016, In: Journal of Pharmacology and Experimental Therapeutics. 359, 1, p. 62-72 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside

    Li, Q., Jiang, Xuye, Zhou, Y., Gu, Y., Ding, Y., Luo, J., Pang, N., Sun, Y., Pei, L., Pan, J., Gao, M., Ma, S., Xiao, Y., Hu, D., Wu, F. & Yang, L., 2023, In: International Journal of Molecular Sciences. 24, 12, 19 p., 10015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Impact of abdominal obesity on postprandial lipid concentrations

    Christiansen, Malene Revsbech, Sørensen, Thorkild I.A., Hansen, Torben & Kilpeläinen, Tuomas O., 2020, In: European Journal of Human Genetics. 28, Suppl. 1, p. 279-280 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  16. Published

    Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 34 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, Johanne Marie, Kleber, M. E., Hollensted, M., Aadahl, Mette, Færch, K., Grarup, Niels, drb459, drb459, Sørensen, Thorkild I.A., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye, Loos, Ruth, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., EPIC-InterAct Consortium, E. C. & PAGE Consortium, P. C., 1 Apr 2017, In: PLOS Genetics. 13, 4, e1006528.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. C., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, Johanne Marie, Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., De Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, Niels, Haitjema, S., Hallmans, G., Hamsten, A., Hansen, Torben, Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J., Jarvelin, M. R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, Allan René, Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., Mckenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. B., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, Oluf Borbye, Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, Thorkild I.A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., drb459, drb459, Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, Tuomas O., Liu, C., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities

    Huang, L. O., Rauch, A., Mazzaferro, E., Preuss, M., Carobbio, S., Bayrak, C. S., Chami, N., Wang, Z., Schick, U. M., Yang, N., Itan, Y., Vidal-Puig, A., den Hoed, M., Mandrup, S., Kilpeläinen, Tuomas O. & Loos, R. J. F., 2021, In: Nature Metabolism. 3, 2, p. 228-243 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, Niels, Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

    Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C-A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T. & 43 others, Feitosa, M. F., Lai, C., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, Thorkild I.A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, Oluf Borbye, Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., 2018, In: Molecular Nutrition & Food Research. 62, 3, p. 1-12 12 p., 1700347.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Genetic variation, adipokines, and cardiometabolic disease

    Metz, Sophia, Huang, L. O. & Kilpeläinen, Tuomas O., 2020, In: Current Opinion in Pharmacology. 52, p. 33-39 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Genetic studies indicate that fetal - and not maternal - insulin resistance is associated with birth weight

    Jakupovic, Hermina, García Ureña, Mario, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 592-593 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Published

    Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents

    Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Lintu, N., Lind, M. V., Atalay, M., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Larnkjær, A., Pedersen, O. B., Holm, J-C., Michaelsen, K. F., Lakka, T. A., Lehtimäki, T., Raitakari, O. & 2 others, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: International Journal of Obesity. 43, p. 2007-2016 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children

    Schnurr, T. M., Viitasalo, A., Eloranta, A., Damsgaard, Camilla Trab, Mahendran, Y., Have, C. T., Väistö, J., Hjorth, Mads Fiil, Christensen, L. B., Brage, S., Atalay, M., Lyytikäinen, L., Lindi, V., Lakka, T., Michaelsen, Kim F., Kilpeläinen, Tuomas O. & Hansen, Torben, 2018, In: International Journal of Obesity. 42, 1, p. 111-114 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

    Mahendran, Y., Jonsson, Anna Elisabet, Have, C. T., Allin, K. H., Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 10 Feb 2017, In: Diabetologia. 60, 5, p. 873-878 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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