- 2019
- Published
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J. & 263 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, A. R., Sung, Y. J., Brown, M. R., Winkler, T. W., Kraja, A. T., Ntalla, I., Schwander, K., Chasman, D. I., Lim, E., Deng, X., Guo, X., Liu, J., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F. & 32 others, , Apr 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, , Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training
Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria
Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jorgensen, M. E., Grarup, N. & 9 others, , 2019, In: Diabetologia. 62, 2, p. 292-305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abdominal adiposity and cardiometabolic risk factors in children and adolescents: A Mendelian randomization analysis
Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Atalay, M., Lind, M. V., Heikkinen, S., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Carrasquilla, G. D., Larnkjær, A., Pedersen, O., Michaelsen, K. F., Lakka, T. A., Holm, J-C., Lehtimäki, T. & 3 others, , 2019, In: American Journal of Clinical Nutrition. 110, 5, p. 1079-1087 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study
Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J-F., Ahluwalia, T. V. S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T. O., Kleber, M. E. & 31 others, , 2019, In: JAMA Network Open. 2, 9, 18 p., e1910915.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis
Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B. & 27 others, , 2019, In: Addiction. 114, 2, p. 216-225 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits
Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, , 2019, In: American Journal of Human Genetics. 104, 1, p. 112-138 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies
Huang, T., Sun, D., Heianza, Y., Bergholdt, H. K. M., Gao, M., Fang, Z., Ding, M., Frazier-Wood, A. C., North, K. E., Marouli, E., Graff, M., Smith, C. E., Varbo, A., Lemaitre, R. N., Corella, D., Wang, C. A., Tjønneland, A., Overvad, K., Sørensen, T. I. A., Feitosa, M. F. & 36 others, , 2019, In: Clinical Chemistry. 65, 6, p. 751-760 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary Fat and the Genetic Risk of Type 2 Diabetes
Carrasquilla, Germán D., Jakupovic, Hermina & Kilpeläinen, Tuomas O., 2019, In: Current Diabetes Reports. 19, 6 p., 109.Research output: Contribution to journal › Review › Research › peer-review
- Published
Disentangling the genetics of lean mass
Karasik, D., Zillikens, M. C., Hsu, Y. H., Aghdassi, A., Akesson, K., Amin, N., Barroso, I., Bennett, D. A., Bertram, L., Bochud, M., Borecki, I. B., Broer, L., Buchman, A. S., Byberg, L., Campbell, H., Campos-Obando, N., Cauley, J. A., Cawthon, P. M., Chambers, J. C., Chen, Z. & 137 others, , 2019, In: American Journal of Clinical Nutrition. 109, 2, p. 276-287Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?
Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity
Dallner, O. S., Marinis, J. M., Lu, Y., Birsoy, K., Werner, E., Fayzikhodjaeva, G., Dill, B. D., Molina, H., Moscati, A., Kutalik, Z., Marques-Vidal, P., Kilpeläinen, Tuomas O., Grarup, Niels, Linneberg, Allan René, Zhang, Y., Vaughan, R., Loos, Ruth, Lazar, M. A. & Friedman, J. M., 2019, In: Nature Medicine. 25, 3, p. 507-530 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology: [incl. correction]
Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I. & 31 others, , 2019, In: American Journal of Human Genetics. 105, 1, p. 15-28 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents
Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Lintu, N., Lind, M. V., Atalay, M., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Larnkjær, A., Pedersen, O. B., Holm, J-C., Michaelsen, K. F., Lakka, T. A., Lehtimäki, T., Raitakari, O. & 2 others, , 2019, In: International Journal of Obesity. 43, p. 2007-2016 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal Associations of Fitness, Motor Competence, and Adiposity with Cognition
Haapala, E. A., Lintu, N., Vaisto, J., Tompuri, T., Soininen, S., Viitasalo, A., Eloranta, A., Venalainen, T., Saakslahti, A., Laitinen, T. & Lakka, T. A., 2019, In: Medicine and Science in Sports and Exercise. 51, 3, p. 465-471Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry Genome-wide Meta-analysis Accounting for Gene-education Interactions in Up to 227,850 Individuals Identifies Several Novel Lipid Loci
Sung, Y. J., Schwander, K. L., Bentley, A. R., de Vries, P. S., Kilpeläinen, Tuomas O., Noordam, R., Musani, S. K., Aschard, H., de las Fuentes, L. & CHARGE Gene-Lifestyle Interactions, C. G. I., 2019, In: Genetic Epidemiology. 43, 7, p. 912-912 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., Manning, A., Aschard, H., Brown, M. R., Chen, H., Franceschini, N., Musani, S. K., Richard, M., Vojinovic, D., Aslibekyan, S., Bartz, T. M. & 128 others, , 2019, In: Nature Communications. 10, 1, 13 p., 5121.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Kilpeläinen, T. O., Bentley, A. R., Noordam, R., Sung, Y. J., Schwander, K., Winkler, T. W., Jakupović, H., Chasman, D. I., Manning, A., Ntalla, I., Aschard, H., Brown, M. R., de las Fuentes, L., Franceschini, N., Guo, X., Vojinovic, D., Aslibekyan, S., Feitosa, M. F., Kho, M., Musani, S. K. & 32 others, , 2019, In: Nature Communications. 10, 11 p., 376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R., Aschard, H. & 32 others, , 2019, In: American Journal of Epidemiology. 188, 6, p. 1033-1054Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity and unfavourable lifestyle increase type 2 diabetes-risk independent of genetic predisposition
Jakupovic, Hermina, Schnurr, T. M., Carrasquilla, Germán D., Grarup, Niels, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: Diabetologia. 62, Suppl. 1, p. S188 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis
Merino, J., Guasch-Ferré, M., Ellervik, C., Dashti, H. S., Sharp, S. J., Wu, P., Overvad, K., Sarnowski, C., Kuokkanen, M., Lemaitre, R. N., Justice, A. E., Ericson, U., Braun, K. V. E., Mahendran, Y., Frazier-Wood, A. C., Sun, D., Chu, A. Y., Tanaka, T., Luan, J., Hong, J. & 48 others, , 2019, In: BMJ (Clinical research ed.). 366, p. l4292Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions
Osazuwa-Peters, O. L., Schwander, K., Waken, R. J., de Las Fuentes, L., Kilpeläinen, Tuomas O., Loos, R. J. F., Racette, S. B., Sung, Y. J. & Rao, D. C., 2019, In: Human Heredity. 83, 6, p. 315-332Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children
Schnurr, T. M., Viitasalo, A., Eloranta, A., Damsgaard, Camilla Trab, Mahendran, Y., Have, C. T., Väistö, J., Hjorth, Mads Fiil, Christensen, L. B., Brage, S., Atalay, M., Lyytikäinen, L., Lindi, V., Lakka, T., Michaelsen, Kim F., Kilpeläinen, Tuomas O. & Hansen, Torben, 2018, In: International Journal of Obesity. 42, 1, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
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