Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

    Alm, P. S., de Castro Barbosa, T., Barrès, Romain, Krook, A. & Zierath, Juleen R, Jul 2017, In: Molecular Metabolism. 6, 7, p. 621-630 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up

    Almdal, Thomas Peter, Scharling, H., Jensen, J. S. & drb459, drb459, 12 Jul 2004, In: J A M A Internal Medicine. 164, 13, p. 1422-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Glucagon immunoneutralization in diabetic rats normalizes urea synthesis and decreases nitrogen wasting

    Almdal, T. P., Holst, Jens Juul & Vilstrup, H., 1992, In: Diabetes. 41, p. 12-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Genetic determinants of circulating GIP and GLP-1 concentrations

    Almgren, P., Lindqvist, A., Krus, U., Hakaste, L., Ottosson-Laakso, E., Asplund, O., Sonestedt, E., Prasad, R. B., Laurila, E., Orho-Melander, M., Melander, O., Tuomi, T., Holst, Jens Juul, Nilsson, P. M., Wierup, N., Groop, L. & Ahlqvist, E., 2 Nov 2017, In: JCI insight. 2, 21, 13 p., e93306.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

    Almind, K., Bjørbaek, C., drb459, drb459, Hansen, Torben, Echwald, S. M. & Pedersen, Oluf Borbye, 2 Oct 1993, In: Lancet. 342, 8875, p. 828-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity

    Almind, K., Frederiksen, S. K., Bernal, D., Hansen, Torben, Ambye, L., Urhammer, Søren Asger, Ekstrøm, Claus Thorn, Berglund, L., Reneland, R., Lithell, H., White, M. F., Van Obberghen, E. & Pedersen, Oluf Borbye, 11 Oct 1999, In: Diabetologia. 42, 10, p. 1244-1249 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

    Almind, K., Delahaye, L., Hansen, Torben, Van Obberghen, E., Pedersen, Oluf Borbye & Kahn, C. R., 19 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2124-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats

    Alonge, K. M., Mirzadeh, Z., Scarlett, J. M., Logsdon, A. F., Brown, Jenny, Cabrales, E., Chan, C. K., Kaiyala, K. J., Bentsen, M. A., Banks, W. A., Guttman, M., Wight, T. N., Morton, G. J. & Schwartz, M. W., 2020, In: Nature Metabolism. 2, 10, p. 1025-1033 11 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  9. Published

    Hypothalamic chondroitin sulfate glycosaminoglycan matrix assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats

    Alonge, K. M., Mirzadeh, Z., Scarlett, J. M., Logsdon, A. F., Brown, Jenny, Cabrales, E., Chan, C. K., Kaiyala, K. J., Bentsen, M. A., Banks, W. A., Guttman, M., Wight, T. N., Morton, G. J. & Schwartz, M. W., 2020, In: Glycobiology. 30, 12, p. 1032-1033 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  10. Published

    Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT

    Alssema, M., Rijkelijkhuizen, J. M., Holst, Jens Juul, Teerlink, T., Scheffer, P. G., Eekhoff, E. M. W., Gastaldelli, A., Mari, A., Hart, L. M., Nijpels, G. & Dekker, J. M., Oct 2013, In: European Journal of Endocrinology. 169, 4, p. 421-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Quantification of oxidative stress phenotypes based on high-throughput growth profiling of protein kinase and phosphatase knockouts.

    Altıntaş, Ali, 11 Nov 2015, In: FEMS Yeast Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development

    Altıntaş, Ali, Laker, R. C., Garde, C., Barrès, Romain & Zierath, Juleen R, 2020, In: Epigenomics. 12, 8, p. 701-713

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action

    Altıntaş, Ali, Liu, J., Fabre, O., Chuang, T., Wang, Y., Sakurai, R., Chehabi, G. N., Barrès, Romain & Rehan, V. K., 2021, In: F A S E B Journal. 35, 7, e21702.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis

    Alvarez Silva, Maria Camila, Schierwagen, R., Pohlmann, A., Magdaleno, F., Uschner, F. E., Ryan, P., Vehreschild, M. J. G. T., Claria, J., Latz, E., Lelouvier, B., Arumugam, Mani & Trebicka, J., 2019, In: Frontiers in Immunology. 10, 11 p., 69.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India

    Alvarez-Silva, C., Kashani, A., Hansen, T. H., Pinna, N. K., Anjana, R. M., Dutta, A., Saxena, S., Støy, J., Kampmann, U., Nielsen, T., Jørgensen, T., Gnanaprakash, V., Gnanavadivel, R., Sukumaran, A., Rani, C. S. S., Færch, K., Radha, V., Balasubramanyam, M., Nair, G. B., Das, B. & 6 others, drb459, drb459, Hansen, Torben, Mande, S. S., Mohan, V., Arumugam, Mani & Pedersen, Oluf Borbye, 2021, In: Genome Medicine. 13, 37.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The role of the mycobiota in the gut-liver axis

    Alvarez Silva, Maria Camila, Brach, Thorsten, Brejnrod, A. D. & Arumugam, Mani, 9 Nov 2018, The Human Gut-Liver-Axis in Health and Disease. Springer, p. 133-145 13 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  17. Published

    Effects of a self-prepared carbohydrate-reduced high-protein diet on cardiovascular disease risk markers in patients with type 2 diabetes

    Alzahrani, A. H., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Frystyk, J., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: Nutrients. 13, 5, 10 p., 1694.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet

    Alzahrani, A. H. A., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: European Journal of Nutrition. 60, 8, p. 4473-4482 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Ligand-selective small molecule modulators of the constitutively active vGPCR US28

    Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In: European Journal of Medicinal Chemistry. 155, p. 244-254

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile

    Amlacher, S., Sarges, P., Flemming, D., van Noort, V., Kunze, R., Devos, D. P., Arumugam, Mani, Bork, P. & Hurt, E., 2011, In: Cell. 146, 2, p. 277-89 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

    Amrutkar, M., Cansby, E., Chursa, U., Nuñez-Durán, E., Chanclón, B., Ståhlman, M., Fridén, V., Mannerås-Holm, L., Wickman, A., Smith, U., Bäckhed, G. F., Borén, J., Howell, B. W. & Mahlapuu, M., Aug 2015, In: Diabetes. 64, 8, p. 2791-804 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    Associations of hypoglycaemia and glycaemic variability with cardiac arrhythmias using a long-term monitoring approach in insulin-treated patients with type 2 diabetes

    Andersen, A., Bagger, J. I., Sorensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-135 257.

    Research output: Contribution to journal › Conference abstract in journal › Research

  25. Published

    A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes

    Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Drugs. 81, p. 1003-1030 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Glucagon-like peptide 1 in health and disease

    Andersen, A., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Nature Reviews Endocrinology. 14, p. 390-403

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Hypoglycaemia and cardiac arrhythmias in diabetes

    Andersen, A., Jørgensen, P. G., Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Therapeutic Advances in Endocrinology and Metabolism. 11, 11 p., 2042018820911803.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Associations of hypoglycemia, glycemic variability and risk of cardiac arrhythmias in insulin-treated patients with type 2 diabetes: a prospective, observational study

    Andersen, A., Bagger, J. I., Sørensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Cardiovascular Diabetology. 20, 1, 10 p., 241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls

    Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

    Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Glukagonlignende peptid 1-receptoragonister til behandling af type 2-diabetes

    Andersen, A., Christensen, A. S., Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Ugeskrift for Laeger. 181, 2, V10180725.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Weight gain in different periods of pregnancy and offspring's body mass index at 7 years of age

    Andersen, C. S., Gamborg, M., Sørensen, Thorkild I.A. & Nohr, E. A., 2011, In: International Journal of Pediatric Obesity. 6, 2-2, p. e179-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Prenatal Exposures to Perfluorinated Chemicals and Anthropometry at 7 Years of Age

    Andersen, C. S., Fei, C., Gamborg, M., Nohr, E. A., Sørensen, Thorkild I.A. & Olsen, J., 2013, In: American Journal of Epidemiology. 178, 6, p. 921-927 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Prenatal exposures to perfluorinated chemicals and anthropometric measures in infancy

    Andersen, C. S., Fei, C., Gamborg, Michael Orland, Nohr, E. A., Sørensen, Thorkild I.A. & Olsen, J., 1 Dec 2010, In: American Journal of Epidemiology. 172, 11, p. 1230-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Peptides in the regulation of glucagon secretion

    Andersen, Daniel Bjørklund & Holst, Jens Juul, 2022, In: Peptides. 148, 19 p., 170683.

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Preadipocytes from obese humans with type 2 diabetes are epigenetically reprogrammed at genes controlling adipose tissue function

    Andersen, E., Ingerslev, L. R., Fabre, O., Donkin, I., Altıntaş, Ali, Versteyhe, S., Bisgaard, T., Kristiansen, V. B., Simar, D. & Barrès, Romain, 2019, In: International Journal of Obesity. 43, 2, p. 306-318 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Environmental factors influence the epigenetic signature of newborns from mothers with gestational diabetes

    Andersen, E., Altıntaş, Ali, Andersson-Hall, U., Holmäng, A. & Barrès, Romain, 2019, In: Epigenomics. 11, 8, p. 861-873 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

    Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

    Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors?

    Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17¿636 Danes

    Andersen, G., Dalgaard, L. T., Justesen, Johanne Marie, Anthonsen, S., Nielsen, T., Thørner, L. W., Witte, D., Jørgensen, T., Clausen, J. O., Lauritzen, T., Holmkvist, J., Hansen, Torben & Pedersen, Oluf Borbye, 2012, In: International Journal of Obesity.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites

    Andersen, G., Wegner, L., Jensen, D. P., Glümer, C., Tarnow, L., Drivsholm, Thomas, Poulsen, P., Hansen, S. K., Nielsen, E. D., Ek, J., Mouritzen, P., Vaag, A., Parving, H., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 1 Apr 2005, In: Hypertension. 45, 4, p. 565-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects

    Andersen, G., Burgdorf, K. S., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 5, p. 1427-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Impact of weight-loss management on children and adolescents with obesity and obstructive sleep apnea

    Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, 2019, In: International Journal of Pediatric Otorhinolaryngology. 123, p. 57-62

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Obstructive sleep apnea in children and adolescents with and without obesity

    Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, 2019, In: European Archives of Oto-Rhino-Laryngology. 276, 3, p. 871-878

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Obstructive sleep apnea in obese children and adolescents, treatment methods and outcome of treatment: A systematic review

    Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, Aug 2016, In: International Journal of Pediatric Otorhinolaryngology. 87, p. 190-7 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

    Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Healthcare Burden in Greenland of Gastrointestinal Symptoms in Adults with Inherited Loss of Sucrase-Isomaltase Function

    Andersen, K., Hansen, Torben, Jørgensen, M. E. & Senftleber, N., 2024, In: Application of Clinical Genetics. 17, p. 15-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Birth weight, childhood body mass index and risk of coronary heart disease in adults: combined historical cohort studies

    Andersen, L. G., Ängquist, Lars, Eriksson, J. G., Forsen, T., Gamborg, Michael Orland, Osmond, C., Baker, J. L. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 11, p. e14126

    Research output: Contribution to journal › Journal article › Research › peer-review

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