Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Fibroblast growth factor 21: an endocrine inhibitor of sugar and alcohol appetite

    Holstein-Rønsbo, Stephanie & Gillum, M. P., 2019, In: The Journal of Physiology. 597, 14, p. 3539-3548 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

    von Holstein-Rathlou, S., BonDurant, L. D., Peltekian, L., Naber, M. C., Yin, T. C., Claflin, K. E., Urizar, A. I., Madsen, A. N., Ratner, C., Holst, B., Karstoft, K., Vandenbeuch, A., Anderson, C. B., Cassell, M. D., Thompson, A. P., Solomon, T. P., Rahmouni, K., Kinnamon, S. C., Pieper, A. A., Gillum, M. P. & 1 others, Potthoff, M. J., 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 335-43 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Aetiological factors behind adipose tissue inflammation: an unexplored research area

    von Scholten, B. J., Andresen, E. N., Sørensen, Thorkild I.A. & Jess, T., 2013, In: Public Health Nutrition. 16, 1, p. 27-35 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Urinary biomarkers are associated with incident cardiovascular disease, all-cause mortality and deterioration of kidney function in type 2 diabetic patients with microalbuminuria

    von Scholten, B. J., Reinhard, H., Hansen, Tine Willum, Oellgaard, J., Parving, H., Jacobsen, P. K. & Rossing, Peter, Jul 2016, In: Diabetologia. 59, 7, p. 1549–1557

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease

    Ádori, C., Glück, L., Barde, S., Yoshitake, T., Kovacs, G. G., Mulder, J., Maglóczky, Z., Havas, L., Bölcskei, K., Mitsios, N., Uhlén, M., Szolcsányi, J., Kehr, J., Rönnbäck, A., Schwartz, Thue W., Rehfeld, Jens Frederik, Harkany, T., Palkovits, M., Schulz, S. & Hökfelt, T., Apr 2015, In: Acta Neuropathologica. 129, 4, p. 541-63 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Combined effects of weight loss and physical activity on all-cause mortality of overweight men and women

    ÿstergaard, J. N., Grønbaek, M., Schnohr, P., Sørensen, Thorkild I.A. & Heitmann, Berit, 2010, In: International Journal of Obesity. 34, 4, p. 760-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Improving the calculation of statistical significance in genome-wide scans

    Ängquist, Lars & Hössjer, O., 1 Oct 2005, In: Biostatistics. 6, 4, p. 520-538 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Ängquist, Lars, Baker, J. L., Damsgaard, Camilla Trab, Eliasen, M., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A., Jørgensen, T., Tang Møllehave, L., Thuesen, B. H., Osler, Merete & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C., 2019, In: Nature. 569, 7755, p. 260-264 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  10. Published

    Strategies for conditional two-locus nonparametric linkage analysis

    Ängquist, Lars, Hössjer, O. & Groop, L., 1 Jul 2008, In: Human Heredity. 66, 3, p. 138-156 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Using importance sampling to improve simulation in linkage analysis

    Ängquist, Lars & Hössjer, O., 1 Jan 2004, In: Statistical Applications in Genetics and Molecular Biology. 3, 1, 5.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Stata tip 92: Manual implementation of permutations and bootstraps

    Ängquist, Lars, 1 Dec 2010, In: Stata Journal. 10, 4, p. 686-688 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications (Summary)

    Ängquist, Lars, 2007, In: Qvartilen. 22, 2, p. 25-26

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A Somewhat Subjective Introduction to Gene Mapping through Nonparametric Linkage Analysis

    Ängquist, Lars, 2008, Genetic Recombination Research Progress. Schultz, J. H. (ed.). Nova Biomedical Books, 60 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    A Unified Discussion on the Concept of Score Functions Used in the Context of Nonparametric Linkage Analysis

    Ängquist, Lars, 2008, In: Bioinformatics and Biology Insights. 2, p. 119-132 PMID:19812770.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications

    Ängquist, Lars, 2007, 250 p.

    Research output: Book/Report › Ph.D. thesis › Research

  17. Published

    Endurance training improves GLP-1 sensitivity and glucose tolerance in overweight women

    Åkerström, T., Stolpe, Malene Norup, Widmer, R., Dejgaard, T. F., Højberg, J. M., Møller, Kirsten, Hansen, J. S., Trinh, B., Holst, Jens Juul, Thomsen, C., Pedersen, Bente Klarlund & Ellingsgaard, H., 2022, In: Journal of the Endocrine Society. 6, 9, p. 1-8 8 p., bvac111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

    Ægidius, H. M., Veidal, S. S., Feigh, M., Hallenborg, P., Puglia, M., Pers, Tune H, Vrang, N., Jelsing, J., Kornum, Birgitte Rahbek, Blagoev, B. & Rigbolt, K. T. G., 2020, In: Scientific Reports. 10, 1, 12 p., 1148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    High body mass index and risk of exacerbations and pneumonias in individuals with chronic obstructive pulmonary disease: observational and genetic risk estimates from the Copenhagen General Population Study

    Çolak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, Oct 2016, In: International Journal of Epidemiology. 45, 5, p. 1551-1559 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Majority of never-smokers with airflow limitation do not have asthma: the Copenhagen General Population Study

    Çolak, Y., Afzal, Shoaib, Nordestgaard, Børge & Lange, Peter, Jul 2016, In: Thorax. 71, 7, p. 614-623 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Increased mortality in patients hospitalized with primary hyperparathyroidism during the period 1977-1993 in Denmark

    Øgard, C. G., Engholm, G., Almdal, Thomas Peter & drb459, drb459, Jan 2004, In: World Journal of Surgery. 28, 1, p. 108-11 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Parathyroid scintigraphy during hypocalcaemia in primary hyperparathyroidism

    Øgard, C. G., drb459, drb459, Thomsen, J. B., Jakobsen, H., Almdal, Thomas Peter, Nielsen, S. L. & drb459, drb459, May 2005, In: Clinical Physiology and Functional Imaging. 25, 3, p. 166-70 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Mediastinalt parathyroideacysteadenom--en sjaelden årsag til primaer hyperparatyroidisme

    Øgard, C. G., Nielsen, S. L., Jakobsen, H., Leth-Espensen, P., drb459, drb459 & drb459, drb459, 28 Aug 2006, In: Ugeskrift for Laeger. 168, 35, p. 2921-2 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Counterregulatory responses to postprandial hypoglycemia after Roux-en-Y gastric bypass

    Øhrstrøm, C. C., Hansen, D. L., Kielgast, U. L., Bergmann, M. L., Veedfald, Simon, Holst, Jens Juul & Worm, Dorte, 2021, In: Surgery for Obesity and Related Diseases. 17, 1, p. 55-63 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A role for exogenous GLP-1 in the management of postprandial hypoglycaemia after Roux-en-Y gastric bypass?

    Øhrstrøm, C. C. & Knop, Filip Krag, 2019, In: European Journal of Endocrinology. 181, 3, p. C5-C8

    Research output: Contribution to journal › Comment/debate › Research

  26. Published

    Evidence for Relationship Between Early Dumping and Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass

    Øhrstrøm, C. C., Worm, Dorte, Kielgast, U. L., Holst, Jens Juul & Hansen, D. L., 2020, In: Obesity Surgery. 30, 3, p. 1038-1045

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man

    Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656

    Research output: Contribution to journal › Journal article › Research

  28. Published

    The effects of soy isoflavones on obesity

    Ørgaard, A. & Jensen, L., 5 Jun 2008, In: Experimental Biology and Medicine (Maywood). 233, 9, p. 1066-80 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice

    Ørgaard, A., Jepsen, Sara Lind & Holst, Jens Juul, 2019, In: Islets. 11, 5, p. 103-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice

    Ørgaard, A. & Holst, Jens Juul, Sep 2017, In: Diabetologia. 60, 9, p. 1731-1739 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects.

    Ørskov, C. & Holst, Jens Juul, 1995, Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, p. 513-516

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  32. Published

    Proglucagon products in plasma of uraemic patients and normals in the fasting state

    Ørskov, C., Andreasen, J. & Holst, Jens Juul, 1992, In: J. Clin. Endocrinol. Metab.. 74, p. 379-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    All products of proglucagon are elevated in plasma from ureamic patients

    Ørskov, Cathrine, Andreasen, J. & Holst, Jens Juul, 1992, In: Journal of Clinical Endocrinology and Metabolism. 79, p. 379-383

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man

    Ørskov, C., Rabenhøj, L., Kofod, H., Wettergren, A. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-39

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting-state and after oral glucose and intravenous arginine

    Ørskov, C., Jeppesen, J., Madsbad, J. & Holst, Jens Juul, 1991, In: J. Clin. Invest.. 87, p. 415-423

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Increased All-Cause Mortality in Patients With Type 1 Diabetes and High-Expression Mannan-Binding Lectin Genotypes: A 12-Year Follow-up Study

    Østergaard, J. A., Thiel, S., Lajer, M., Steffensen, R., Parving, H., Flyvbjerg, A., Rossing, Peter, Tarnow, L. & Hansen, T. K., Oct 2015, In: Diabetes Care. 38, 10, p. 1898-1903 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Provision of amniotic fluid during parenteral nutrition increases weight gain with limited effects on gut structure, function, immunity, and microbiology in newborn preterm pigs

    Østergaard, M. V., Shen, René Liang, Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, Dennis Sandris, Hartmann, Bolette, Bering, S. B., Schmidt, M. & Sangild, Per Torp, 2016, In: Journal of Parenteral and Enteral Nutrition. 40, 4, p. 552-566 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

    Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

    NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Afzal, Shoaib, Michaelsen, Kim F., Damsgaard, Camilla Trab, Sørensen, Thorkild I.A. & Ängquist, Lars, 2020, In: Lancet. 396, 10261, p. 1511-1524 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

    NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Damsgaard, Camilla Trab, Michaelsen, Kim F., Afzal, Shoaib, Ängquist, Lars, Bojesen, Stig Egil, Frikke-Schmidt, Ruth, Molbo, Drude, Mortensen, Erik Lykke, Nordestgaard, Børge, Sørensen, Thorkild I.A. & Varbo, A., 2021, In: eLife. 10, 35 p., e60060.

    Research output: Contribution to journal › Journal article › Research › peer-review

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