Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 1994
  2. Published

    Sympathoadrenal regulation of adrenal androstenedione release

    Ehrhart-Bornstein, M., Bornstein, S. R., Behling, H. G., Holst, Jens Juul, Strohmayer, H. G., Rasmussen, T. N., Scherbaum, W. A. & Adler, G., 1994, In: Neuroendocrinology. 59, p. 406-412

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Expression of glycogen synthase and phosphofructokinase in muscle from type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment

    drb459, drb459, Andersen, P. H., Lund, S., Vedel, P. & Pedersen, Oluf Borbye, Jan 1994, In: Diabetologia. 37, 1, p. 82-90 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The multifactorial and multistage character of protective immunity to Plasmodium falciparum, naturally acquired by an indigenous population in Burkina Faso

    Boudin, C., Sheick, I., Chumpitazi, B., Pazart, L., Høgh, Birthe, Peyron, F., Deloron, P., Picot, S. & Ambroise-Thomas, P., Apr 1994, In: Scandinavian Journal of Immunology. 39, 4, p. 409-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Peptide-evoked release of amylase from isolated acini of the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, Steen Seier & Holst, Jens Juul, 26 May 1994, In: Regulatory Peptides. 51, 3, p. 237-54 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM

    Bjørbaek, C., Echwald, S. M., Hubricht, P., drb459, drb459, Hansen, Torben, Zierath, Juleen R & Pedersen, Oluf Borbye, Aug 1994, In: Diabetes. 43, 8, p. 976-83 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Immune responses to band 3 neoantigens on Plasmodium falciparum-infected erythrocytes in subjects living in an area of intense malaria transmission are associated with low parasite density and high hematocrit value

    Høgh, Birthe, Petersen, E., Crandall, I., Gottschau, A. & Sherman, I. W., Oct 1994, In: Infection and Immunity. 62, 10, p. 4362-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM

    Chen, Y. H., Hansen, L., Chen, M., Bjørbaek, C., drb459, drb459, Hansen, Teis Schjals, Cohen, P., Pedersen, Oluf Borbye & drb459, drb459, Oct 1994, In: Diabetes. 43, 10, p. 1234-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 1995
  15. Published

    A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin

    Hansen, L., Hansen, T., drb459, drb459, Bjørbæk, C., Echwald, S. M., Clausen, J. O., Chen, Y. H., Chen, M. X., Cohen, P. T. W. & Pedersen, O., 1995, In: Human Molecular Genetics. 4, 8, p. 1313-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.

    Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.

    Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.

    Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.

    Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Histochemical, pharmacological, biochemical and chromatographic evidence that pituitary adenylyl cyclase activating peptide is involved in inhibitory neurotransm.in the taenia of the guinea-pig caecum

    McConalogue, K., Furness, J. B., Vremec, M. A., Holst, Jens Juul, Tornøe, K. & Marley, P. D., 1995, In: J. Autonom Nerv. System. 50, p. 311-322

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Human Glucagon-like peptide-1, - six important topics.

    Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  26. Published

    Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Ileal release of glucagonlike peptide-1 (GLP-1): association with inhibition of gastric acid in humans

    Layer, P., Holst, Jens Juul, Grandt, D. & Goebell, H., 1995, In: Digestive Disease Science. 40, p. 1074-82

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Increases in plasma motilin follow each episode of gallbladder emptying during the interdigestive period and changes in serum bile acid concentration correlate to plasma motilin.

    Qvist, N., Øster-Jørgensen, E., Pedersen, S. A., Rasmussen, L., Hovendal, C. & Holst, Jens Juul, 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 122-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships

    Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8

    Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Postprandial glucagon-like peptide-1 (GLP-1) release in states of normal and disturbed luminal nutrient digestion.

    Layer, P., v d Ohe, M. & Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 547-550

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  33. Published

    Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.

    Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Presence of somatostatin containing neuronal-like cells in the rat pineal gland.

    Møller, M., Holst, Jens Juul, Mikkelsen, J. D. & Webb, S., 1995, In: Neuroendocrinol. Letters. 17, p. 71-80

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects.

    Ørskov, C. & Holst, Jens Juul, 1995, Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, p. 513-516

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  36. Published

    Sympathoadrenal regulation of adrenocortical steroidogenesis

    Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.

    Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia

    Madsen, O. D., Karlsen, C., Blume, N., Jensen, H. I., Larsson, L. & Holst, Jens Juul, 1995, In: Scand. J. Clin. Lab. Invest.. 55, suppl. 220, p. 27-36

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coli

    Theisen, Michael, Vuust, J., Gottschau, A., Jepsen, S. & Høgh, Birthe, Jan 1995, In: Clinical and Vaccine Immunology. 2, 1, p. 30-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients

    Bjørbaek, C., Vik, T. A., Echwald, S. M., Yang, P. Y., drb459, drb459, Wang, J. P., Webb, G. C., Richmond, K., Hansen, T. & Erikson, R. L., Jan 1995, In: Diabetes. 44, 1, p. 90-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Specific and nonspecific responses to Plasmodium falciparum blood-stage parasites and observations on the gametocytemia in schoolchildren living in a malaria-endemic area of Mozambique

    Høgh, Birthe, Thompson, R., Hetzel, C., Fleck, S. L., Kruse, N. A., Jones, I., Dgedge, M., Barreto, J. & Sinden, R. E., Jan 1995, In: American Journal of Tropical Medicine and Hygiene. 52, 1, p. 50-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study

    drb459, drb459, Weinreb, J. E., Rosen, A. S., Bjørbaek, C., Hansen, L., Pedersen, Oluf Borbye & Kahn, B. B., Jan 1995, In: The Journal of clinical endocrinology and metabolism. 80, 1, p. 270-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

    Echwald, S. M., Bjørbaek, C., Hansen, Torben, Clausen, J. O., drb459, drb459, Zierath, Juleen R, Printz, R. L., Granner, D. K. & Pedersen, Oluf Borbye, Mar 1995, In: Diabetes. 44, 3, p. 347-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Insulin-resistant glucose metabolism in patients with microvascular angina--syndrome X

    drb459, drb459, Skøtt, P., Steffensen, R., Wroblewski, H., Pedersen, O. & Kastrup, J., Jul 1995, In: Metabolism. 44, 7, p. 876-82 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Molecular characterization of a 40-kDa outer membrane protein, FomA, of Fusobacterium periodonticum and comparison with Fusobacterium nucleatum

    Bolstad, A. I., Høgh, Birthe & Jensen, H. B., Oct 1995, In: Oral Microbiology and Immunology. 10, 5, p. 257-64 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Molecular mechanism of action of non-peptide ligands for peptide receptors

    Schwartz, Thue W., Gether, Ulrik, Schambye, H. T. & Hjorth, Siv Annegrethe, Oct 1995, In: Current Pharmaceutical Design. 1, 3, p. 325-342 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control

    drb459, drb459, Lund, S., Bjørbaek, C. & Pedersen, Oluf Borbye, Oct 1995, In: Diabetologia. 38, 10, p. 1230-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM

    Klein, H. H., drb459, drb459, Kotzke, G. & Pedersen, Oluf Borbye, Nov 1995, In: Diabetes. 44, 11, p. 1310-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants

    Gottschau, A. & Høgh, Birthe, 30 Dec 1995, In: Statistics in Medicine. 14, 24, p. 2727-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 1996
  51. Published

    Clinical and parasitological studies on immunity to Plasmodium falciparum malaria in children

    Høgh, Birthe, 1996, In: Scandinavian Journal of Infectious Diseases. Supplementum. 102, p. 1-53 53 p.

    Research output: Contribution to journal › Journal article › Research

  52. Published

    Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP

    Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1996. 1 p.

    Research output: Contribution to conference › Paper › Research

  53. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover

    Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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