Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 1996
  2. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch

    Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.

    Research output: Contribution to conferencePosterResearch

  3. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

    Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes

    Damm, Peter, drb459, drb459, Kühl, C. E. & Pedersen, Oluf Borbye, Feb 1996, In: American Journal of Obstetrics and Gynecology. 174, 2, p. 722-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Studies of insulin resistance in congenital generalized lipodystrophy

    Søvik, O., drb459, drb459, Trygstad, O. & Pedersen, Oluf Borbye, Jun 1996, In: Acta Paediatrica. Supplement. 413, p. 29-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Handedness in twins according to zygosity and chorion type: a preliminary report

    Derom, C., Thiery, E., Vlietinck, R., Loos, Ruth & Derom, R., Jul 1996, In: Behavior Genetics. 26, 4, p. 407-8 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cloning of the fomA gene, encoding the major outer membrane porin of Fusobacterium nucleatum ATCC10953

    Jensen, H. B., Skeidsvoll, J., Fjellbirkeland, A., Høgh, Birthe, Puntervoll, P., Kleivdal, H. & Tommassen, J., Nov 1996, In: Microbial Pathogenesis. 21, 5, p. 331-42 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 1997
  9. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  10. Published

    Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index

    Hansen, Torben, Andersen, C. B., Echwald, S. M., Urhammer, S. A., Clausen, J. O., drb459, drb459, Owens, D., Hansen, L. & Pedersen, Oluf Borbye, Mar 1997, In: Diabetes. 46, 3, p. 494-501 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus

    Vestergaard, H., Rossen, M., Urhammer, S. A., Müller, J. & Pedersen, Oluf Borbye, May 1997, In: European Journal of Endocrinology. 136, 5, p. 475-82 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Population studies of the human V kappa A18 gene polymorphism in Caucasians, blacks and Eskimos. New functional alleles and evidence for evolutionary selection of a more restricted antibody repertoire

    Juul, Lars, Hougs, L., Andersen, V., Garred, Peter, Ryder, L., Svejgaard, A., Høgh, Birthe, Lamm, L., Graugaard, B. & Barington, T., Jun 1997, In: Tissue Antigens. 49, 6, p. 595-604 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM

    Hansen, L., Arden, K. C., Rasmussen, S. B., Viars, C. S., drb459, drb459, Hansen, Teis Schjals, Møller, A. M., Woodgett, J. R. & Pedersen, Oluf Borbye, Aug 1997, In: Diabetologia. 40, 8, p. 940-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Expression of protein-tyrosine phosphatases in the major insulin target tissues

    Norris, K., Norris, F., Kono, D. H., drb459, drb459, Pedersen, Oluf Borbye, Theofilopoulos, A. N. & Møller, N. P., 6 Oct 1997, In: FEBS Letters. 415, 3, p. 243-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Matola malaria project: a temporal and spatial study of malaria transmission and disease in a suburban area of Maputo, Mozambique

    Thompson, R., Begtrup, K., Cuamba, N., Dgedge, M., Mendis, C., Gamage-Mendis, A., Enosse, S. M., Barreto, J., Sinden, R. E. & Høgh, Birthe, Nov 1997, In: American Journal of Tropical Medicine and Hygiene. 57, 5, p. 550-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 1998
  17. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The differing impact of chloroquine and pyrimethamine/sulfadoxine upon the infectivity of malaria species to the mosquito vector

    Høgh, Birthe, Gamage-Mendis, A., Butcher, G. A., Thompson, R., Begtrup, K., Mendis, C., Enosse, S. M., Dgedge, M., Barreto, J., Eling, W. & Sinden, R. E., Feb 1998, In: American Journal of Tropical Medicine and Hygiene. 58, 2, p. 176-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Decarboxylation-based traceless linking with Aroyl acrylic acids

    Garibay, P., Nielsen, J. & Hoeg-Jensen, T., 9 Apr 1998, In: Tetrahedron Letters. 39, 15, p. 2207-2210 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Nye farmaka til behandling af malaria

    Høgh, Birthe, 10 Aug 1998, In: Ugeskrift for Laeger. 160, 33, p. 4783-6 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America

    Madsen, H. O., Satz, M. L., Høgh, Birthe, Svejgaard, A. & Garred, Peter, 15 Sep 1998, In: Journal of immunology (Baltimore, Md. : 1950). 161, 6, p. 3169-75 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients

    Urhammer, Søren Asger, Møller, Ann, Nyholm, B., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Clausen, J. O., Hansen, Torben, Pedersen, Oluf Borbye & Schmitz, O., 20 Nov 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 11, p. 3992-3995 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. 1999
  28. Published

    Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    Vorwerk, P., Christoffersen, C. T., Müller, J., drb459, drb459, Pedersen, Oluf Borbye, De Meyts, P. & drb459, drb459, 1999, In: Hormone Research. 52, 5, p. 211-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Bivariant periodic cyclic homology

    Grønbæk, Christian, 1999, USA: Chapman & Hall/CRC. (Research Notes in Mathematics).

    Research output: Book/ReportBookResearchpeer-review

  30. Published

    Intermediate Expansions of a GAA Repeat in the Frataxin Gene are not associated with Type 2 Diabetes or Altered Glucose-Induced ¿-cell function in Danish Caucasians

    Dalgaard, L. T., Hansen, T., Urhammer, S. A., Clausen, J. O., Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1999, In: Diabetes. 48, p. 914-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Low incidence rate of overt hypothyroidism compared with hyperthyroidism in an area with moderately low iodine intake

    Laurberg, P., Bülow Pedersen, I., Pedersen, K. M. & drb459, drb459, Jan 1999, In: Thyroid. 9, 1, p. 33-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

    Klein, H. H., Müller, R., drb459, drb459 & Pedersen, Oluf Borbye, Feb 1999, In: Diabetologia. 42, 2, p. 245-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism

    drb459, drb459, Feb 1999, In: Danish Medical Bulletin (Print). 46, 1, p. 13-34 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Intact proinsulin and beta-cell function in lean and obese subjects with and without type 2 diabetes

    Røder, M. E., Dinesen, B., Hartling, S. G., Houssa, P., drb459, drb459, Sodoyez-Goffaux, F. & Binder, C., Apr 1999, In: Diabetes Care. Supplement. 22, 4, p. 609-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Insulin resistance, exercise capacity and body composition in subjects with two hypertensive parents

    Andersen, U. B., Dige-Petersen, H., Ibsen, H., Skøtt, P., Bruun, Niels Eske, drb459, drb459 & Christiansen, C., Sep 1999, In: Journal of Hypertension. 17, 9, p. 1273-80 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity

    Almind, K., Frederiksen, S. K., Bernal, D., Hansen, Torben, Ambye, L., Urhammer, Søren Asger, Ekstrøm, Claus Thorn, Berglund, L., Reneland, R., Lithell, H., White, M. F., Van Obberghen, E. & Pedersen, Oluf Borbye, 11 Oct 1999, In: Diabetologia. 42, 10, p. 1244-1249 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2000
  40. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

    Schmidt, P. T., Hartmann, Bolette, Bregenholt, S., Holst, Jens Juul & Claesson, Mogens Helweg, 1 May 2000, In: Scandinavian Journal of Gastroenterology. 35, 5, p. 522-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, P. B., Sep 2000, In: Gut. 47, 3, p. 370-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation

    Huang, D., Han, Y., Rani, M. R., Glabinski, A., Trebst, C., Sørensen, Torben Lykke, Tani, M., Wang, J., Chien, P., O'Bryan, S., Bielecki, B., Zhou, Z., Majumder, S. & Ransohoff, R. M., Oct 2000, In: Immunological Reviews. 177, p. 52-67 16 p.

    Research output: Contribution to journalJournal articleResearch

  44. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Interaktion mellem warfarin og oral miconazol-gel

    Ogard, C. G. & drb459, drb459, 9 Oct 2000, In: Ugeskrift for Laeger. 162, 41, p. 5511

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus

    Rasmussen, S. K., Lautier, C., Hansen, L., Echwald, S. M., Hansen, Torben, Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Borch-Johnsen, K., Grigorescu, F., Smith, R. J. & Pedersen, Oluf Borbye, 1 Dec 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1606-1610 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2001
  48. Published

    A prevalent polymorphism in the putative promotor of the UCP3 gene and its relationship to body mass index in the Danish population

    Dalgaard, L. T., Sørensen, Thorkild I.A., Drivsholm, T. B., Borch-Johnsen, K., Andersen, T., Hansen, T. & Pedersen, Oluf Borbye, 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, p. 1398-1402

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

    Buemann, B., Schierning, B., Toubro, S., Bibby, B. M., Sørensen, Thorkild I.A., Dalgaard, L., Pedersen, Oluf Borbye & Astrup, A., 2001, In: International Journal of Obesity. 25, p. 467-471 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus

    Hansen, L., Jensen, J. N., Ekstrøm, Claus Thorn, drb459, drb459, Hansen, Teis Schjals, Pedersen, Oluf Borbye & drb459, drb459, Feb 2001, In: Diabetologia. 44, 2, p. 237-240 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Center for epidemiologisk grundforskning.

    Olsen, J., Melbye, M., Sørensen, Thorkild I.A. & Aaby, P., 26 Feb 2001, In: Ugeskrift for Laeger. 163, 9, p. 1296-1297 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul & Mortensen, P. B., Mar 2001, In: Gastroenterology. 120, 4, p. 806-815 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Serum leptin levels in pregnant women with type 1 diabetes mellitus

    Lauszus, F., Schmitz, O., drb459, drb459, Klebe, J. G., Pedersen, Oluf Borbye & drb459, drb459, Jul 2001, In: Acta Obstetricia et Gynecologica Scandinavica. 80, 7, p. 596-601 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Increments in insulin sensitivity during intensive treatment are closely correlated with decrements in glucocorticoid receptor mRNA in skeletal muscle from patients with Type II diabetes

    drb459, drb459, Bratholm, P. & Christensen, Niels Johan, Nov 2001, In: Clinical Science. 101, 5, p. 533-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism

    drb459, drb459, Lund, S., Pedersen, Oluf Borbye & drb459, drb459, Nov 2001, In: Journal of Internal Medicine. 250, 5, p. 406-14 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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