Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

    Holst, Birgitte, Nygaard, R., Hansen, L. V., Bach, Anders, Engelstoft, M. S., Petersen, P. S., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 6, p. 3973-85 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A cost analysis of intensified vs conventional multifactorial therapy in individuals with type 2 diabetes: a post hoc analysis of the Steno-2 study

    Gæde, J., Oellgaard, J., Ibsen, R., Gæde, P., Nortoft, E., Parving, H., Kjellberg, J. & Pedersen, Oluf Borbye, 2019, In: Diabetologia. 62, 1, p. 147-155

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A decade of genome discoveries in type 2 diabetes and metabolism

    Grarup, Niels, 2020, University of Copenhagen. 72 p.

    Research output: Book/Report › Doctoral thesis › Research

  4. Published

    A diet-induced gut microbiota component and related plasma metabolites are associated with depressive-like behaviour in rats

    Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Lund, S. & Wegener, G., 2021, In: European Neuropsychopharmacology. 43, p. 10-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients

    Naimi, R. M., Madsen, K. B., Askov-Hansen, C., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 47-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

    Chinnaswamy, S., Wardzynska, A., Pawelczyk, M., Makowska, J., Skaaby, T., Mercader, J. M., Ahluwalia, T. S., Grarup, Niels, Guindo-Martinez, M., Bisgaard, H., Torrents, D., Linneberg, Allan René, Bønnelykke, Klaus & Kowalski, M. L., 5 Sep 2017, In: Scientific Reports. 7, 1, p. 1-11 11 p., 10500.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk

    Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

    de Vries, P. S., Reventun, P., Brown, M. R., Heath, A. S., Huffman, J. E., Le, N. Q., Bebo, A., Brody, J. A., Temprano-Sagrera, G., Raffield, L. M., Ozel, A. B., Thibord, F., Jain, D., Lewis, J. P., Rodriguez, B. A. T., Pankratz, N., Taylor, K. D., Polasek, O., Chen, M. H., Yanek, L. R. & 32 others, Carrasquilla, Germán D., Marioni, R. E., Kleber, M. E., Trégouët, D. A., Yao, J., Li-Gao, R., Joshi, P. K., Trompet, S., Martinez-Perez, A., Ghanbari, M., Howard, T. E., Reiner, A. P., Arvanitis, M., Ryan, K. A., Bartz, T. M., Rudan, I., Faraday, N., Linneberg, Allan René, Ekunwe, L., Davies, G., Delgado, G. E., Hansen, Torben, Chen, W. M., Jackson, Rebecca, Liu, Y., Loos, Ruth, Rao, Divya, Wang, L., Nielsen, J. B., Kilpeläinen, Tuomas O., Trans-Omics for Precision Medicine (TOPMed) program, T. F. P. M. (. P. & the INVENT consortium, T. I. C., 2 May 2024, In: Blood. 143, 18, p. 1845-1855 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A genetic map of the mouse dorsal vagal complex and its role in obesity

    Ludwig, M. Q., Cheng, W., Gordian, D., Lee, J., Paulsen, S. J., Hansen, S. N., Egerod, Kristoffer Lihme, Barkholt, P., Rhodes, C. J., Secher, A., Knudsen, L. B., Pyke, C., Myers, M. G. & Pers, Tune H, 2021, In: Nature Metabolism. 3, p. 530-545

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals

    Krarup, N. T., Borglykke, A., Allin, K. H., Sandholt, C. H., Justesen, Johanne Marie, Andersson, E. A., Grarup, Niels, Jørgensen, T., Pedersen, O. & Hansen, T., Jun 2015, In: Atherosclerosis. 240, 2, p. 305-10 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A genome-wide association meta-analysis identifies new childhood obesity loci

    Bradfield, J. P., Taal, H. R., Timpson, N. J., Scherag, A., Lecoeur, C., Warrington, N. M., Hypponen, E., Holst, C., Valcarcel, B., Thiering, E., Salem, R. M., Schumacher, F. R., Cousminer, D. L., Sleiman, P. M. A., Zhao, J., Berkowitz, R. I., Vimaleswaran, K. S., Jarick, I., Pennell, C. E., Evans, D. M. & 31 others, St Pourcain, B., Berry, D. J., Mook-Kanamori, D. O., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., van Duijn, C. M., van der Valk, R. J. P., de Jongste, J. C., Postma, D. S., Boomsma, D. I., Gauderman, W. J., Hassanein, M. T., Lindgren, C. M., Mägi, R., Boreham, C. A. G., Neville, C. E., Moreno, L. A., Elliott, P., Pouta, A., Hartikainen, A., Li, M., Raitakari, O., Lehtimäki, T., Eriksson, J. G., Palotie, A., Dallongeville, J., Das, S., Bisgaard, H., Sørensen, Thorkild I.A. & Early Growth Genetics Consortium, E. G. G. C., 2012, In: Nature Genetics. 44, 5, p. 526-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A genome-wide association search for type 2 diabetes genes in African Americans

    Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N. & 31 others, Ng, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Grarup, Niels, Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye, Schwarz, Peter, Karpe, F. & DIAGRAM Consortium, D. C., 2012, In: P L o S One. 7, 1, p. e29202

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

    Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, Oluf Borbye, Kamatani, N., Nakamura, Y. & Kadowaki, T., 1 Oct 2010, In: Nature Genetics. 42, 10, p. 864-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

    Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Lajer, M., Ahluwalia, T. S. & 7 others, Linneberg, Allan René, Witte, D. R., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Rossing, Peter & SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium, S. M. F. M. A. M. H. E. F. I. D. T. (. C., 2018, In: Diabetes. 67, 7, p. 1414-1427 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

    Surakka, I., Whitfield, J. B., Perola, M., Visscher, P. M., Montgomery, G. W., Falchi, M., Willemsen, G., de Geus, E. J. C., Magnusson, P. K. E., Christensen, K., Sørensen, T. I. A., Pietiläinen, K. H., Rantanen, T., Silander, K., Widén, E., Muilu, J., Rahman, I., Liljedahl, U., Syvänen, A-C., Palotie, A. & 9 others, Kaprio, J., Kyvik, K. O., Pedersen, N. L., Boomsma, D. I., Spector, T., Martin, N. G., Ripatti, S., Peltonen, L. & GenomEUtwin Project, G. P., 2012, In: Twin Research and Human Genetics. 15, 6, p. 691-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

    Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, Buil, A., Thompson, W. K., Geschwind, D. H. & Werge, Thomas, Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

    Nielsen, T. R. H., Appel, E. V. R., Svendstrup, M., Ohrt, J. D., Dahl, M., Fonvig, C. E., Hollensted, M., Have, C. T., Kadarmideen, H. N., Pedersen, Oluf Borbye, Hansen, Torben, Holm, Jens-Christian & Grarup, Niels, 2017, In: PloS one. 12, 3, 16 p., e0174204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

    Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, The International Headache Genetics Consortium, T. I. H. G. C. & the 23andMe Research Team, T. 2. R. T., 2020, In: Nature Communications. 11, 1, 3368.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity

    Frayling, T. M., Lindgren, C. M., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A. & 9 others, Cognet, I., Hansen, Torben, Pedersen, Oluf Borbye, Ellard, S., Tuomi, T., Groop, L. C., Froguel, P., Hattersley, A. T. & Vaxillaire, M., 2003, In: Diabetes. 52, 3, p. 872-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

    Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, Allan René, Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Mueller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quiros, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sanchez, M., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., van der A, D. L., van der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Aponte, J. L., Butterworth, A., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, Torben, Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., Langenberg, C., McCarthy, M. I., Pankow, J. S., Pedersen, Oluf Borbye, Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J. & Waterworth, D. M., 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A genomic mutational constraint map using variation in 76,156 human genomes

    Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., Poterba, T., Wilson, M. W., Tarasova, Y., Phu, W., Grant, R., Yohannes, M. T., Koenig, Z., Farjoun, Y., Banks, E., Donnelly, S. & 18 others, Gabriel, S., Gupta, N., Ferriera, S., Tolonen, C., Novod, S., Bergelson, L., Roazen, D., Ruano-Rubio, V., Covarrubias, M., Llanwarne, C., Petrillo, N., Wade, G., Jeandet, T., Munshi, R., Tibbetts, K., Loos, Ruth, Karczewski, K. J. & Genome Aggregation Database Consortium, G. A. D. C., 2024, In: Nature. 625, 7993, p. 92-100 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

    Stacey, S. N., Sulem, P., Jonasdottir, A., Masson, G., Gudmundsson, J., Gudbjartsson, D. F., Magnusson, O. T., Gudjonsson, S. A., Sigurgeirsson, B., Thorisdottir, K., Ragnarsson, R., Benediktsdottir, K. R., Nexø, B. A., Tjønneland, A., Overvad, K., Rudnai, P., Gurzau, E., Koppova, K., Hemminki, K., Corredera, C. & 31 others, Fuentelsaz, V., Grasa, P., Navarrete, S., Fuertes, F., García-Prats, M. D., Sanambrosio, E., Panadero, A., De Juan, A., Garcia, A., Rivera, F., Planelles, D., Soriano, V., Requena, C., Aben, K. K., van Rossum, M. M., Cremers, R. G. H. M., van Oort, I. M., van Spronsen, D., Schalken, J. A., Peters, W. H. M., Helfand, B. T., Donovan, J. L., Hamdy, F. C., Badescu, D., Codreanu, O., Banasik, Karina, Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye & Swedish Low-risk Colorectal Cancer Study Group, S. L. C. C. S. G., 1 Jan 2011, In: Nature Genetics. 43, 11, p. 1098-1103 6 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  23. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A glycogene mutation map for discovery of diseases of glycosylation

    Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, Niels, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A gut feeling about glucagon: Eje Prize 2018

    Knop, Filip Krag, 2018, In: European Journal of Endocrinology. 178, 6, p. R267-R280 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    A hospital-based child and adolescent overweight and obesity treatment protocol transferred into a community healthcare setting

    Mollerup, P. M., Gamborg, Michael Orland, Trier, C., Bøjsøe, C., Nielsen, T. R. H., Baker, J. L. & Holm, Jens-Christian, 2017, In: PLOS ONE. 12, 3, 17 p., e0173033.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A house of collaboration: investigating the intersections of art and biomedicine

    Arnold, Ken, Bencard, Adam, Pedersen, B. V., Söderqvist, Thomas, Tybjerg, Karin & Whiteley, Louise, 2019, Art and Science in Museums. Rossi-Linnemann, C. & di Martini, G. (eds.). 1 ed. Routledge, (Routledge Research in Museum Studies).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  28. Published

    A human gut microbial gene catalogue established by metagenomic sequencing

    MetaHIT Consortium, M. C., 2010, In: Nature. 464, 7285, p. 59-65 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A large-scale RNA interference screen identifies genes that regulate autophagy at different stages

    Guo, S., Pridham, K. J., Virbasius, C., He, B., Zhang, L., Varmark, H., Green, M. R. & Sheng, Z., 2018, In: Scientific Reports. 8, 1, p. 1-15 2822.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A large-scale screen for coding variants predisposing to psoriasis

    Tang, H., Jin, X., Li, Y., Jiang, H., Tang, X., Yang, X., Cheng, H., Qiu, Y., Chen, G., Mei, J., Zhou, F., Wu, R., Zuo, X., Zhang, Y., Zheng, X., Cai, Q., Yin, X., Quan, C., Shao, H., Cui, Y. & 47 others, Tian, F., Zhao, X., Liu, H., Xiao, F., Xu, F., Han, J., Shi, D., Zhang, A., Zhou, C., Li, Q., Fan, X., Lin, L., Tian, H., Wang, Z., Fu, H., Wang, F., Yang, B., Huang, S., Liang, B., Xie, X., Ren, Y., Gu, Q., Wen, G., Sun, Y., Wu, X., Dang, L., Xia, M., Shan, J., Li, T., Yang, L., Zhang, X., Li, Y., He, C., Xu, A., Wei, L., Zhao, X., Gao, X., Xu, J., Zhang, F., Zhang, J., Li, Y., Sun, L., Liu, J., Chen, R., Yang, S., Wang, J. & Zhang, X., 2014, In: Nature Genetics. 46, 1, p. 45-+ 8 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  31. Published

    A literature review of evidence for primary prevention of overweight and obesity in healthy weight children and adolescents: A report produced by a working group of the Danish Council on Health and Disease Prevention

    Olsen, N. J., Østergaard, J. N., Bjerregaard, L. G., Høy, T. V., Kierkegaard, L., Michaelsen, Kim F., Sørensen, Thorkild I.A., Grønbæk, M. K., Bruun, J. M. & Heitmann, Berit, 2023, In: Obesity Reviews. 25, 1, 10 p., e13641.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    A liver specific gene that is expressed in growth hormone transgenic mice and in normal female mice as a function of age

    Tiong, J. D. R., Gosney, E., Ding, J., Chin, E. & Kopchick, J. J., 1 Jun 2006, In: Growth Hormone and IGF Research. 16, 3, p. 145-156 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    A longitudinal study of seroreactivities to Plasmodium falciparum antigens in infants and children living in a holoendemic area of Liberia

    Høgh, Birthe, Marbiah, N. T., Petersen, E., Perlmann, H., Dolopaye, E., Hanson, A. P., Bjorkman, A. & Perlmann, P., Feb 1991, In: American Journal of Tropical Medicine and Hygiene. 44, 2, p. 191-200 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women

    Krog-Mikkelsen, I., Sloth, B., Dimitrov, D., Tetens, Inge , Björck, I., Flint, A., Holst, Jens Juul, Astrup, A., Elmstähl, H. & Raben, Anne, 2011, In: Journal of Nutrition. 141, 9, p. 1679-1684 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

    Hansen, L. B. S., Roager, H. M., Søndertoft, N. B., Gøbel, R. J., Kristensen, M. B., Vallès-Colomer, M., Vieira-Silva, S., Ibrügger, S., Lind, M. V., Mærkedahl, R. B., Bahl, M. I., Madsen, M. L., Havelund, J., Falony, G., Tetens, I., Nielsen, T., Allin, K. H., Frandsen, H. L., Hartmann, B., Holst, J. J. & 32 others, Sparholt, M. H., Holck, J., Blennow, Andreas, Moll, J. M., Meyer, A. S., Hoppe, C., Poulsen, J. H., Carvalho, V., Sagnelli, D., Dalgaard, M. D., Christensen, A. F., Lydolph, M., Ross, A. B., Villas-Bôas, S. G., Brix, S., Sicheritz-Pontén, T., Buschard, K., Linneberg, Allan René, Rumessen, J. J., Ekstrøm, Claus Thorn, Ritz, C., Kristiansen, Karsten, Nielsen, H. B., drb459, drb459, Færgeman, N. J., Raes, J., Frøkiær, Hanne, Hansen, Torben, Lauritzen, Lotte, Gupta, R., Licht, T. R. & Pedersen, Oluf Borbye, 2018, In: Nature Communications. 9, 13 p., 4630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A machine learning approach to short-term body weight prediction in a dietary intervention program

    Babajide, O., Hissam, T., Anna, P., Anatoliy, G., Astrup, A., Alfredo Martinez, J., Oppert, J. & Sørensen, Thorkild I.A., 2020, Computational Science - ICCS 2020: 20th International Conference, Amsterdam, The Netherlands, June 3-5, 2020. Proceedings, Part IV. Krzhizhanovskaya, V. V., Zavodszky, G., Lees, M. H., Sloot, P. M. A., Dongarra, J. J., Brissos, S. & Teixeira, J. (eds.). Springer, p. 441-455 15 p. (Lecture Notes in Computer Science, Vol. 12140).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  37. Published

    A maternal low protein diet has pronounced effects on mitochondrial gene expression in offspring liver and skeletal muscle; protective effect of taurine

    Mortensen, Ole Hartvig, Olsen, H. L., Frandsen, L., Nielsen, Peter E., Nielsen, Finn Cilius, Grunnet, N. & Quistorff, B., 1 Aug 2010, In: Journal of Biomedical Science. 24, 17, p. 1-11

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

    de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M-H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R. & 111 others, Yanek, L. R., Ahluwalia, Tarun Veer Singh, Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L. M., Oldmeadow, C., Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Willemsen, G., Rumley, A., Fiorillo, E., de Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Lopez, L. M., Berentzen, T. L., Räikkönen, K., Mangino, M., Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D., Wright, A. F., Marten, J., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., de Maat, M. P. M., de Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M., Khaw, K., McKnight, B., Huang, J., Jenny, N. S., Holliday, E. G., Qi, L., McEvoy, M. G., Becker, D. M., Starr, J. M., Sarin, A., Hysi, P. G., Hernandez, D. G., Jhun, M. A., Campbell, H., Hamsten, A., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Koenig, W., Psaty, B. M., Haritunians, T., Liu, J., Palotie, A., Uitterlinden, A. G., Stott, D. J., Hofman, A., Franco, O. H., Polasek, O., Rudan, I., Morange, P., Wilson, J. F., Kardia, S. L. R., Ferrucci, L., Spector, T. D., Eriksson, J. G., Hansen, Torben, Deary, I. J., Becker, L. C., Scott, R. J., Mitchell, P., März, W., Wareham, N. J., Peters, A., Greinacher, A., Wild, P. S., Jukema, J. W., Boomsma, D. I., Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 2016, In: Human Molecular Genetics. 25, 2, p. 358-370 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van Der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppala, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N. & 64 others, Becker, E. J., Beekman, M., Blanche, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnaso, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylha, M., Kahonen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimaki, T., Lieb, W., Lyytikainen, L., Martin-Ruiz, C., Min, J., Nebe, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psat, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, Thorkild I.A., D Taylor, K., Uitterlinden, A. G., van Der Flier, W., van Der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., 2019, In: Nature Communications. 10, 14 p., 3669.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    A metabolic prosurvival role for PML in breast cancer

    Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A metabolite roadmap of the wood-forming tissue in Populus tremula

    Abreu, I. N., Johansson, A. I., Sokolowska, K., Niittyla, T., Sundberg, B., Hvidsten, T. R., Street, N. R. & Moritz, Thomas, 2020, In: New Phytologist. 228, p. 1559-1572 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    A metabolomic study of Gomphrena agrestis in Brazilian Cerrado suggests drought-adaptive strategies on metabolism

    Melo, G. A., Abreu, I. N., de Oliveira, M. B., Budzinski, I. G. F., Silva, L. V., Silva Pimenta, M. A. & Moritz, Thomas, 2021, In: Scientific Reports. 11, 13 p., 12933.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    A metagenome-wide association study of gut microbiota in type 2 diabetes

    Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., Peng, Y., Zhang, D., Jie, Z., Wu, W., Qin, Y., Xue, W., Li, J., Han, L., Lu, D., Wu, P. & 36 others, Dai, Y., Sun, X., Li, Z., Tang, A., Zhong, S., Li, X., Chen, W., Xu, R., Wang, M., Feng, Q., Gong, M., Yu, J., Zhang, Y., Zhang, M., Hansen, Torben, Sanchez, G., Raes, J., Falony, G., Okuda, S., Almeida, M., LeChatelier, E., Renault, P., Pons, N., Batto, J., Zhang, Z., Chen, H., Yang, R., Zheng, W., Li, S., Yang, H., Wang, J., Ehrlich, S. D., Nielsen, R., Pedersen, Oluf Borbye, Kristiansen, Karsten & Wang, J., 2012, In: Nature. 490, 7418, p. 55-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    A method for noninvasive detection of fetal large deletions/duplications by low coverage massively parallel sequencing

    Chen, S., Lau, T. K., Zhang, C., Xu, C., Xu, Z., Hu, P., Xu, J., Huang, H., Pan, L., Jiang, F., Chen, F., Pan, X., Xie, W., Liu, P., Li, X., Zhang, L., Li, S., Li, Y., Xu, X., Wang, W. & 3 others, Wang, J., Jiang, H. & Zhang, X., 2013, In: Prenatal Diagnosis. 33, 6, p. 584-590 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    A molecular census of arcuate hypothalamus and median eminence cell types

    Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

    Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J. & 263 others, Musani, S. K., Kilpelainen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F., Jackson, A. U., Kammerer, C. M., Kasturiratne, A., Komulainen, P., Kuehnel, B., Leander, K., Lee, W., Lin, K., Luan, J., Lyytikainen, L., McKenzie, C. A., Nelson, C. P., Noordam, R., Scott, R. A., Sheu, W. H. H., Stancakova, A., Takeuchi, F., van Der Most, P. J., V Varga, Tibor, Waken, R. J., Wang, H., Wang, Y., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Alfred, T., Amin, N., Arking, D. E., Aung, T., Barr, R. G., Bielak, L. F., Boerwinkle, E., Bottinger, E. P., Braund, P. S., Brody, J. A., Broeckel, U., Cade, B., Campbell, A., Canouil, M., Chakravarti, A., Cocca, M., Collins, F. S., Connell, J. M., de Mutsert, R., de Silva, H. J., Doerr, M., Duan, Q., Eaton, C. B., Ehret, G., Evangelou, E., Faul, J. D., Forouhi, N. G., Franco, O. H., Friedlander, Y., Gao, H., Gigante, B., Gu, C. C., Gupta, P., Hagenaars, S. P., Harris, T. B., He, J., Heikkinen, S., Heng, C., Hofman, A., Howard, B. V., Hunt, S. C., Irvin, M. R., Jia, Y., Katsuya, T., Kaufman, J., Kerrison, N. D., Khor, C. C., Koh, W., Koistinen, H. A., Kooperberg, C. B., Krieger, J. E., Kubo, M., Kutalik, Z., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. H., Lehne, B., Levy, D., Lewis, C. E., Li, Y., Lim, S. H., Liu, C., Liu, J., Liu, J., Liu, Y., Loh, M., Lohman, K. K., Louie, T., Magi, R., Matsuda, K., Meitinger, T., Metspalu, A., Milani, L., Momozawa, Y., Mosley, T. H. ,. J., Nalls, M. A., Nasri, U., O'Connell, J. R., Ogunniyi, A., Palmas, W. R., Palmer, N. D., Pankow, J. S., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Porteous, D., Raitakari, O. T., Renstrom, F., Rice, T. K., Ridker, P. M., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Sabanayagam, C., Salako, B. L., Sandow, K., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Sims, M., Sitlani, C. M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Wilson, G., Wojczynski, M. K., Xiang, Y., Yao, J., Yu, C., Yuan, J., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Chen, Y. I., Weir, D. R., de Faire, U., Deary, I. J., Esko, T., Farrall, M., Forrester, T., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Hung, Y., Jonas, J. B., Kato, N., Kooner, J. S., Laakso, M., Lehtimaki, T., Liang, K., Magnusson, P. K. E., Oldehinkel, A. J., Pereira, A. C., Perls, T., Rauramaa, R., Redline, S., Rettig, R., Samani, N. J., Scott, J., Shu, X., van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Wickremasinghe, A. R., Wu, T., Kamatani, Y., Laurie, C. C., Bouchard, C., Cooper, R. S., Evans, M. K., Gudnason, V., Hixson, J., Kardia, S. L. R., Kritchevsky, S. B., Psaty, B. M., van Dam, R. M., Arnett, D. K., Mook-Kanamori, D. O., Fornage, M., Fox, E. R., Hayward, C., van Duijn, C. M., Tai, E. S., Wong, T. Y., Loos, Ruth, Reiner, A. P., Rotimi, C. N., Bierut, L. J., Zhu, X., Cupples, L. A., Province, M. A., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C., Morrison, A. C. & Kilpeläinen, Tuomas O., 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

    Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D. & 32 others, Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Zhao, J. H., Aadahl, Mette, Bork-Jensen, J., Møllehave, L. T., Liu, J., Wang, J., drb459, drb459, Jackson, R. D., Kovacs, P., Pedersen, Oluf Borbye, Hansen, Torben, Lind, L., Loos, Ruth, Christensen, K., Linneberg, Allan René, Grarup, Niels, Dantoft, T. M., Karpe, F., Wei, W. Q., Sun, Y. V., Million Veterans Program, M. V. P. & Global Lipids Genetics Consortium, G. L. G. C., 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    A mutation map for human glycoside hydrolase genes

    Hansen, Lars, Husein, D. M., Gericke, B., Hansen, Torben, Pedersen, Oluf Borbye, Tambe, M. A., Freeze, H. H., Naim, H. Y., Henrissat, B., Wandall, Hans H., Clausen, Henrik & Bennett, Eric Paul, 2020, In: Glycobiology. 30, 8, p. 500-515 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

    van der Lee, S. J., Conway, O. J., Jansen, I., Carrasquillo, M. M., Kleineidam, L., van den Akker, E., Hernandez, I., van Eijk, K. R., Stringa, N., Chen, J. A., Zettergren, A., Andlauer, T. F. M., Diez-Fairen, M., Simon-Sanchez, J., Lleo, A., Zetterberg, H., Nygaard, M., Blauwendraat, C., Savage, J. E., Mengel-From, J. & 81 others, Moreno-Grau, S., Wagner, M., Fortea, J., Keogh, M. J., Blennow, K., Skoog, I., Friese, M. A., Pletnikova, O., Zulaica, M., Lage, C., de Rojas, I., Riedel-Heller, S., Illan-Gala, I., Wei, W., Jeune, B., Orellana, A., Bergh, F. T., Wang, X., Hulsman, M., Beker, N., Tesi, N., Morris, C. M., Indakoetxea, B., Collij, L. E., Scherer, M., Morenas-Rodriguez, E., Ironside, J. W., van Berckel, B. N. M., Alcolea, D., Wiendl, H., Strickland, S. L., Pastor, P., Rodriguez Rodriguez, E., Boeve, B. F., Petersen, R. C., Ferman, T. J., van Gerpen, J. A., Reinders, M. J. T., Uitti, R. J., Tarraga, L., Maier, W., Dols-Icardo, O., Kawalia, A., Dalmasso, M. C., Boada, M., Zettl, U. K., van Schoor, N. M., Beekman, M., Allen, M., Masliah, E., Lopez de Munain, A., Pantelyat, A., Wszolek, Z. K., Ross, O. A., Dickson, D. W., Graff-Radford, N. R., Knopman, D., Rademakers, R., Lemstra, A. W., Pijnenburg, Y. A. L., Scheltens, P., Gasser, T., Chinnery, P. F., Hemmer, B., Huisman, M. A., Troncoso, J., Moreno, F., Nohr, E. A., Sørensen, Thorkild I.A., Heutink, P., Sanchez-Juan, P., Posthuma, D., Clarimon, J., Christensen, K., Ertekin-Taner, N., Scholz, S. W., Ramirez, A., Ruiz, A., Slagboom, E., van der Flier, W. M. & Holstege, H., 2019, In: Acta Neuropathologica. 138, 2, p. 237-250 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    A novel -192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α Gene (HNF4A) Associates With Late-onset Diabetes

    Ek, J., Hansen, S. P., Lajer, M., Nicot, C., Boesgaard, T. W., Pruhova, S., Johansen, A., Albrechtsen, Anders, Yderstraede, K., Lauenborg, J., Parrizas, M., Boj, S. F., Jørgensen, T., Borch-Johnsen, K., Damm, Peter, Ferrer, J., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 2006, In: Diabetes. 55, 6, p. 1869-73 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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