Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2024
  2. Published

    Pulmonary maternal immune activation does not cross the placenta but leads to fetal metabolic adaptation

    Hansen, Signe Schmidt Kjølner, Krautz, Robert, Rago, D., Havelund, J., Stigliani, Arnaud, Færgeman, N. J., Prézelin, A., Rivière, J., Couturier-Tarrade, A., Akimov, V., Blagoev, B., Elfving, B., Neess, D., Vogel, U., Khodosevich, Konstantin, Hougaard, Karin Sørig & Sandelin, Albin Gustav, 2024, In: Nature Communications. 15, 24 p., 4711.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Reduced incretin effect precedes diabetes development following duodenopancreatectomy in individuals without diabetes

    Di Giuseppe, G., Soldovieri, L., Ciccarelli, G., Ferraro, P. M., Quero, G., Cinti, F., Capece, U., Moffa, S., Nista, E. C., Gasbarrini, A., Mari, A., Alfieri, S., Tondolo, V., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Mezza, T., 2024, In: Journal of Clinical Investigation. 134, 8, 3 p., e175133.

    Research output: Contribution to journal › Comment/debate › Research

  4. E-pub ahead of print

    Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes

    Fuhri Snethlage, C. M., McDonald, T. J., Oram, R. D., de Groen, P., Rampanelli, E., Schimmel, A. W. M., Holleman, F., Siegelaar, S., Hoekstra, J., Brouwer, C. B., Knop, Filip Krag, Verchere, C. B., van Raalte, D. H., Roep, B. O., Nieuwdorp, M. & Hanssen, N. M. J., 2024, (E-pub ahead of print) In: Diabetes Care. 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Searching for information about stem cells online in an age of artificial intelligence: How should the stem cell community respond?

    Hoeyer, Klaus, Couturier, A., Barawi, K., Drew, C., Grundtvig, Anders, Lane, E., Munk, A. K., Whiteley, Louise & Munsie, M., 2024, In: Stem Cell Reports. 19, 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

    Lennon, N. J., Kottyan, L. C., Kachulis, C., Abul-Husn, N. S., Arias, J., Belbin, G., Below, J. E., Berndt, S. I., Chung, W. K., Cimino, J. J., Clayton, E. W., Connolly, J. J., Crosslin, D. R., Dikilitas, O., Velez Edwards, D. R., Feng, Q. P., Fisher, M., Freimuth, R. R., Ge, T., Glessner, J. T. & 59 others, Gordon, A. S., Patterson, C., Hakonarson, H., Harden, M., Harr, M., Hirschhorn, J., Hoggart, C., Hsu, L., Irvin, M. R., Jarvik, G. P., Karlson, E. W., Khan, A., Khera, A., Kiryluk, K., Kullo, I., Larkin, K., Limdi, N., Linder, J. E., Loos, Ruth, Luo, Y., Malolepsza, E., Manolio, T. A., Martin, L. J., McCarthy, L., McNally, E. M., Meigs, J. B., Mersha, T. B., Mosley, J. D., Musick, A., Namjou, B., Pai, N., Pesce, L. L., Peters, U., Peterson, J. F., Prows, C. A., Puckelwartz, M. J., Rehm, H. L., Roden, D. M., Rosenthal, E. A., Rowley, R., Sawicki, K. T., Schaid, D. J., Smit, Roelof Adriaan Johan, Smith, J. L., Smoller, J. W., Thomas, M., Tiwari, H., Toledo, D. M., Vaitinadin, N. S., Veenstra, D., Walunas, T. L., Wang, Z., Wei, W. Q., Weng, C., Wiesner, G. L., Yin, X., Kenny, E. E., Berndt, S. & Hirschhorn, J., 2024, In: Nature Medicine. 30, 2, p. 480-487 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Signs of Glucagon Resistance After a Two-Week Hypercaloric Diet Intervention

    Suppli, M. P., Høgedal, A., Bagger, J. I., Chabanova, E., van Hall, Gerrit, Forman, Julie Lyng, Christensen, Mikkel Bring, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 4, p. 955–967 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes

    Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Sociodemographic characteristics and COVID-19 testing rates: spatiotemporal patterns and impact of test accessibility in Sweden

    Kennedy, B., Varotsis, G., Hammar, U., Nguyen, D., Carrasquilla, Germán D., van Zoest, V., Kristiansson, R. S., Fitipaldi, H., Dekkers, K. F., Daivadanam, M., Martinell, M., Björk, J. & Fall, T., 2024, In: European Journal of Public Health. 34, 1, p. 14-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Suboptimal Weight Loss 13 Years After Roux-en-Y Gastric Bypass Is Associated with Blunted Appetite Response

    Nymo, S., Lundanes, J., Eriksen, K., Aukan, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Johnsen, G., Græslie, H., Kulseng, B., Sandvik, J. & Martins, C., 2024, In: Obesity Surgery. 34, 2, p. 592-601

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Sugar-sweetened or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in adults: a prospective cohort study

    Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin-Chartier, J. P., Hu, F. B. & Guasch Ferre, Marta, 2024, In: American Journal of Clinical Nutrition. 119, 3, p. 669-681 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment

    Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, Madsen, Kenneth Lindegaard & Clemmensen, Christoffer, 2024, In: Science Advances. 10, 9, 20 p., eadg2636.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Temporal gut microbiota variability and association with dietary patterns: From the one-year observational Diet, Cancer, and Health - Next Generations MAX study

    Rostgaard-Hansen, Agnetha Linn, Esberg, A., Dicksved, J., Hansen, Torben, Pelve, E., Brunius, C., Halkjær, J., Tjønneland, Anne, Johansson, I. & Landberg, R., 2024, In: American Journal of Clinical Nutrition. 119, 4, p. 1015-1026 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions

    Lanfranchi, M., Yandiev, S., Meyer-Dilhet, G., Ellouze, S., Kerkhofs, M., Dos Reis, R., Garcia, A., Blondet, C., Amar, A., Kneppers, A., Polvèche, H., Plassard, D., Foretz, M., Viollet, B., Sakamoto, Kei, Mounier, R., Bourgeois, C. F., Raineteau, O., Goillot, E. & Courchet, J., 2024, In: Nature Communications. 15, 17 p., 2487.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The Taste Liking Questionnaire (TasteLQ) – A tool for assessment of taste liking in the Danish population

    Haydar, Sara, Karlsson, Camilla Cederbye, Linneberg, Allan René, Kårhus, L. L., Ängquist, Lars, Hansen, Torben, Bredie, Wender & Grarup, Niels, 2024, In: Food Quality and Preference. 117, 12 p., 105176.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. E-pub ahead of print

    The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study

    Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A. & 26 others, McDonald, T. J., Kokkola, T., Rutters, F., Beulens, J., Muilwijk, M., Blom, M., Elders, P., Hansen, T. H., Fernandez-Tajes, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, Oluf Borbye, Ruetten, H., Forgie, I., Holst, Jens Juul, Thomsen, Henrik S., Ridderstråle, M., Bell, J. D., Adamski, J., Franks, P. W., Hansen, Torben, Holmes, E., Frost, G. & Pearson, E. R., 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity

    Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The impact of surgery and oncological treatment on risk of type 2 diabetes onset in patients with colorectal cancer: nationwide cohort study in Denmark

    Krag, C., Svane, M. S., Madsbad, Sten, Graversen, S. B., Christensen, J. F., Sørensen, Thorkild I.A., Lehrskov, L. L. & Laurberg, T., 2024, In: eLife. 12, 13 p., RP89354.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The use of a systems approach to increase NAD+ in human participants

    Henderson, John David, Quigley, S. N. Z., Chachra, S. S., Conlon, N. & Ford, D., 2024, In: npj Aging. 10, 12 p., 7.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

    Bradfield, J. P., Kember, R. L., Ulrich, A., Balkiyarova, Z., Alyass, A., Aris, I. M., Bell, J. A., Broadaway, K. A., Chen, Z., Chai, J-F., Davies, N. M., Fernandez-Orth, D., Bustamante, M., Fore, R., Ganguli, A., Heiskala, A., Hottenga, J-J., Íñiguez, C., Kobes, S., Leinonen, J. & 33 others, Lowry, E., Lyytikainen, L., Mahajan, A., Pitkänen, N., Schnurr, T. M., Have, C. T., Strachan, D. P., Thiering, E., Vogelezang, S., Wade, K. H., Wang, C. A., Wong, A., Holm, Louise Aas, Chesi, A., Choong, C., Cruz, M., Elliott, P., Franks, S., Frithioff-Bøjsøe, C., Gauderman, W. J., Glessner, J. T., Gilsanz, V., Griesman, K., Hanson, R. L., Kaakinen, M., Kalkwarf, H., Kelly, A., Hansen, Torben, Holm, Jens-Christian, Sørensen, Thorkild I.A., Grant, S. F. A., Cousminer, D. L. & Early Growth Genetics Consortium, E. G. G. C., 2024, In: Genome Biology. 25, 19 p., 22.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

    Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, Heshmat, R., Razi, F., Karnani, N., Ostovar, A., Farzadfar, F., Tay, S. K. H., Sanders, M. J., Lillycrop, K. A., Godfrey, K. M., Nakagawa, T., Moco, S., Koopman, R., Lynch, G. S., Sorrentino, V. & Feige, J. N., 2024, In: Nature Metabolism. 6, 3, p. 433–447

    Research output: Contribution to journal › Letter › Research › peer-review

  22. Published

    Understanding risk and causal mechanisms for developing obesity in infants and young children: A National Institutes of Health workshop

    Aagaard, K. M., Barkin, S. L., Burant, C. F., Carnell, S., Demerath, E., Donovan, S. M., Eneli, I., Francis, L. A., Gilbert-Diamond, D., Hivert, M. F., LeBourgeois, M. K., Loos, R. J. F., Lumeng, J. C., Miller, A. L., Okely, A. D., Osganian, S. K., Ramirez, A. G., Trasande, L., Van Horn, L. V., Wake, M. & 2 others, Wright, R. J. & Yanovski, S. Z., 2024, In: Obesity Reviews. 25, 4, 21 p., e13690.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Unique features of β-cell metabolism are lost in type 2 diabetes

    Muñoz, F., Fex, M., Moritz, Thomas, Mulder, H. & Cataldo Bascunan, Luis Rodrigo, 2024, In: Acta Physiologica. 240, 6, 21 p., e14148.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Variants at the Interleukin 1 Gene Locus and Pericarditis

    Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, Banasik, Karina, Brunak, Søren, Ivarsdottir, E. V., Sigurdsson, A., Beyter, D., Sturluson, A., Einarsson, H., Tragante, V., Helgason, H., Lund, S. H., Halldorsson, B. V., Sigurpalsdottir, B. D., Olafsson, I., Arnar, D. O., Thorgeirsson, G., Knowlton, K. U., Nadauld, L. D., Gretarsdottir, S., Helgadottir, A., Ostrowski, Sisse Rye, Gudbjartssson, D. F., Jonsdottir, I., Bundgård, Henning, Holm, H., Sulem, P. & Stefansson, K., 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

    Phelps, N. H., Singleton, R. K., Zhou, B., Heap, R. A., Mishra, A., Bennett, J. E., Paciorek, C. J., Lhoste, V. PF., Carrillo-Larco, R. M., Stevens, G. A., Rodriguez-Martinez, A., Bixby, H., Baker, J. L., Aarestrup, J., Afzal, S., Allin, K., Andersen, L. B., Ängquist, L., Bjerregaard, P., Bojesen, S. E. & 31 others, Christensen, K., Damsgaard, Camilla Trab, Dantoft, T. M., Eriksen, L., Giwercman, A., Halkjær, J., Jørgensen, T., Kristensen, P. L., Lind, L., Linneberg, A., Liu, J., Liu, L., Madsen, A. L., Michaelsen, Kim F., Møllehave, Line Tang, Mortensen, Erik Lykke, Nordestgaard, Børge, Osler, Merete, Overvad, K., Schmidt, I. M., Schnohr, P., Schramm, S., Sobngwi, E., Sodemann, M., Sørensen, T. I., Tjonneland, A., Tolstrup, J. S., Wang, Q., Wang, Y. W., Yang, Y. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2024, In: The Lancet. 403, 10431, p. 1027-1050 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. E-pub ahead of print

    Z-Time: Making and feeling time in the chronobiological laboratory

    Hussey, Kristin D., 2024, (E-pub ahead of print) In: Time & Society.

    Research output: Contribution to journal › Journal article › Research › peer-review

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