Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2024
  2. Published

    Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

    Huang, M., Prasad, R. B., Coral, D. E., Hjort, Line, Minja, D. T. R., Mulder, H., Franks, P. W. & Kalamajski, S., 2024, In: Diabetes. 73, 4, p. 637-645

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

    Hughes, O., Bentley, A. R., Breeze, C. E., Aguet, F., Xu, X., Nadkarni, G., Sun, Q., Lin, B. M., Gilliland, T., Meyer, M. C., Du, J., Raffield, L. M., Kramer, H., Morton, R. W., Gouveia, M. H., Atkinson, E. G., Valladares-Salgado, A., Wacher-Rodarte, N., Dueker, N. D., Guo, X. & 54 others, Hai, Y., Adeyemo, A., Best, L. G., Cai, J., Chen, G., Chong, M., Doumatey, A., Eales, J., Goodarzi, M. O., Ipp, E., Irvin, M. R., Jiang, M., Jones, A. C., Kooperberg, C., Krieger, J. E., Lange, E. M., Lanktree, M. B., Lash, J. P., Lotufo, P. A., Loos, Ruth, Ha My, V. T., Peralta-Romero, J., Qi, L., Raffel, L. J., Rich, S. S., Rodriquez, E. J., Tarazona-Santos, E., Taylor, K. D., Umans, J. G., Wen, J., Young, B. A., Yu, Z., Zhang, Y., Ida Chen, Y. D., Rundek, T., Rotter, J. I., Cruz, M., Fornage, M., Lima-Costa, M. F., Pereira, A. C., Paré, G., Natarajan, P., Cole, S. A., Carson, A. P., Lange, L. A., Li, Y., Perez-Stable, E. J., Do, R., Charchar, F. J., Tomaszewski, M., Mychaleckyj, J. C., Rotimi, C., Morris, A. P. & Franceschini, N., 2024, In: Cell Genomics. 4, 1, 13 p., 100468.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. E-pub ahead of print

    Introduction: Laboratory times

    Hussey, Kristin D. & Douglas-Jones, R., 2024, (E-pub ahead of print) In: Time & Society.

    Research output: Contribution to journal › Journal article › Research

  6. Published

    Persistent thinness and anorexia nervosa differ on a genomic level

    Hübel, C., Abdulkadir, M., Herle, M., Palmos, A. B., Loos, Ruth, Breen, G., Micali, Nadia & Bulik, C. M., 2024, In: European Journal of Human Genetics. 32, 1, p. 117-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Impact of acute alcohol consumption on circulating microbiome in asymptomatic alcohol-related liver disease

    Israelsen, M., Alvarez Silva, Maria Camila, Madsen, B. S., Hansen, C. D., Torp, N. C., Johansen, S., Hansen, J. K., Prier Lindvig, K., Insonere, J., Riviere, V., Juel, H. B., Brejnrod, A., Jensen, Lars Juhl, Thiele, M., Lelouvier, B., Hansen, Torben, Arumugam, Mani & Krag, A., 2024, In: Gut. 73, 6, p. 1041-1044 gutjnl-2023-330360.

    Research output: Contribution to journal › Letter › Research › peer-review

  8. Published

    Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

    Jensen, Simon Birk Kjær, Blond, Martin Bæk, Sandsdal, Rasmus Michael, Olsen, L. M., Juhl, C. R., Lundgren, J. R., Janus, C., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2024, In: EClinicalMedicine. 69, 12 p., 102475.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Infections increase the risk of decompensation and death in patients with early alcohol-related liver disease

    Johansen, S., Langkjær, S., Rasmussen, D. N., Israelsen, M., Torp, N., Lindvig, K., Kjærgaard, M., Hansen, J. K., Hansen, C. D., Thorhauge, K., Andersen, P., Detlefsen, S., Juel, H. B., Justesen, U. S., Hansen, Torben, Krag, A., Thiele, M., GALAXY and MicrobLiver consortia, G. A. M. C. & MicrobLiver Consortium, M. C., 2024, In: JHEP Reports. 6, 4, 10 p., 101016.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection

    Kays Mohammed Ali, Y., Dolin, T. G., Damm Nybing, J., Lykke, J., Hvid Linden, F., Høgh-Schmidt, E., Sørensen, Thorkild I.A., Christensen, J. F., Nielsen, Yousef Jesper Wirenfeldt, Stenfatt Larsen, J., Madsbad, Sten, Johansen, Julia Sidenius, Svane, M. S. & Lang Lehrskov, L., 2024, In: International Journal of Obesity. 48, 4, p. 533-541 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Sociodemographic characteristics and COVID-19 testing rates: spatiotemporal patterns and impact of test accessibility in Sweden

    Kennedy, B., Varotsis, G., Hammar, U., Nguyen, D., Carrasquilla, Germán D., van Zoest, V., Kristiansson, R. S., Fitipaldi, H., Dekkers, K. F., Daivadanam, M., Martinell, M., Björk, J. & Fall, T., 2024, In: European Journal of Public Health. 34, 1, p. 14-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

    Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, L. J., Thørner, L. W., Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, P. I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, S. S., Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, T. K., Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Low sphingolipid levels predict poor survival in patients with alcohol-related liver disease

    Kronborg, T. M., Gao, Q., Trošt, K., Lambert, Henriette Ytting, O'Connell, M. B., Werge, M. P., Thing, M., Gluud, Lise Lotte, Hamberg, O., Møller, Søren, Moritz, Thomas, Bendtsen, Flemming & Kimer, N., 2024, In: JHEP Reports. 6, 2, 15 p., 100953.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Harnessing the power of proteomics in precision diabetes medicine

    Kurgan, Nigel Kilty, Larsen, Jeppe Kjærgaard & Deshmukh, Atul Shahaji, 2024, In: Diabetologia. 67, 5, p. 783–797

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions

    Lanfranchi, M., Yandiev, S., Meyer-Dilhet, G., Ellouze, S., Kerkhofs, M., Dos Reis, R., Garcia, A., Blondet, C., Amar, A., Kneppers, A., Polvèche, H., Plassard, D., Foretz, M., Viollet, B., Sakamoto, Kei, Mounier, R., Bourgeois, C. F., Raineteau, O., Goillot, E. & Courchet, J., 2024, In: Nature Communications. 15, 17 p., 2487.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

    Lennon, N. J., Kottyan, L. C., Kachulis, C., Abul-Husn, N. S., Arias, J., Belbin, G., Below, J. E., Berndt, S. I., Chung, W. K., Cimino, J. J., Clayton, E. W., Connolly, J. J., Crosslin, D. R., Dikilitas, O., Velez Edwards, D. R., Feng, Q. P., Fisher, M., Freimuth, R. R., Ge, T., Glessner, J. T. & 59 others, Gordon, A. S., Patterson, C., Hakonarson, H., Harden, M., Harr, M., Hirschhorn, J., Hoggart, C., Hsu, L., Irvin, M. R., Jarvik, G. P., Karlson, E. W., Khan, A., Khera, A., Kiryluk, K., Kullo, I., Larkin, K., Limdi, N., Linder, J. E., Loos, Ruth, Luo, Y., Malolepsza, E., Manolio, T. A., Martin, L. J., McCarthy, L., McNally, E. M., Meigs, J. B., Mersha, T. B., Mosley, J. D., Musick, A., Namjou, B., Pai, N., Pesce, L. L., Peters, U., Peterson, J. F., Prows, C. A., Puckelwartz, M. J., Rehm, H. L., Roden, D. M., Rosenthal, E. A., Rowley, R., Sawicki, K. T., Schaid, D. J., Smit, Roelof Adriaan Johan, Smith, J. L., Smoller, J. W., Thomas, M., Tiwari, H., Toledo, D. M., Vaitinadin, N. S., Veenstra, D., Walunas, T. L., Wang, Z., Wei, W. Q., Weng, C., Wiesner, G. L., Yin, X., Kenny, E. E., Berndt, S. & Hirschhorn, J., 2024, In: Nature Medicine. 30, 2, p. 480-487 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations

    Liu, X., Lin, L., Sinding, M. H. S., Bertola, L. D., Hanghøj, K., Quinn, L., Garcia-Erill, G., Rasmussen, M. S., Schubert, M., Pečnerová, P., Balboa, R. F., Li, Z., Heaton, M. P., Smith, T. P. L., Pinto, R. R., Wang, X., Kuja, J., Brüniche-Olsen, A., Meisner, J., Santander, C. G. & 8 others, Ogutu, J. O., Masembe, C., Rodrigues da Fonseca, Rute Andreia, Muwanika, V., Siegismund, Hans Redlef, Albrechtsen, Anders, Moltke, Ida & Heller, Rasmus, 2024, In: Nature Communications. 15, 1, 16 p., 2921.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. E-pub ahead of print

    Canagliflozin or acarbose versus placebo to ameliorate post-bariatric hypoglycaemia - The HypoBar I randomized clinical trial protocol

    Lobato, C. B., wql596, wql596, Bojsen-Møller, Kirstine Nyvold, Martinussen, C., Veedfald, Simon, Holst, Jens Juul, Madsbad, Sten, Jørgensen, N. B. & Dirksen, Carsten Moro, 2024, (E-pub ahead of print) In: Diabetic Medicine. e15320.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Genetic Variation and Obesity

    Loos, Ruth, 2024, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology. Bray, G. A. & Bouchard, C. (eds.). 4 ed. CRC Press, Vol. 1. p. 113-122 10 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    Pten knockout in mouse preosteoblasts leads to changes in bone turnover and strength.

    Lorenz, J., Richter, S., Kirstein, A. S., Kolbig, F., Nebe, M., Schulze, M., Kiess, W., Spitzbarth, I., Kloting, N., Le Duc, D., Baschant, U. & Garten, A., 2024, In: JBMR Plus. 8, 3, 14 p., ziad016.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

    Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    MCT1 helps brown fat suck up succinate

    Lund, Jens, Isidor, Marie Sophie & Gerhart-Hines, Zach, 2024, In: Nature Metabolism. 6, p. 387–388

    Research output: Contribution to journal › Letter › Research › peer-review

  23. Published

    Plasma metabolite profile of legume consumption and future risk of type 2 diabetes and cardiovascular disease

    Margara-Escudero, H. J., Paz-Graniel, I., García-Gavilán, J., Ruiz-Canela, M., Sun, Q., Clish, C. B., Toledo, E., Corella, D., Estruch, R., Ros, E., Castañer, O., Arós, F., Fiol, M., Guasch-Ferré, M., Lapetra, J., Razquin, C., Dennis, C., Deik, A., Li, J., Gómez-Gracia, E. & 4 others, Babio, N., Martínez-González, M. A., Hu, F. B. & Salas-Salvadó, J., 2024, In: Cardiovascular Diabetology. 23, 1, 13 p., 38.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

    Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, Heshmat, R., Razi, F., Karnani, N., Ostovar, A., Farzadfar, F., Tay, S. K. H., Sanders, M. J., Lillycrop, K. A., Godfrey, K. M., Nakagawa, T., Moco, S., Koopman, R., Lynch, G. S., Sorrentino, V. & Feige, J. N., 2024, In: Nature Metabolism. 6, 3, p. 433–447

    Research output: Contribution to journal › Letter › Research › peer-review

  25. Published

    Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

    Meng, X., Navoly, G., Giannakopoulou, O., Levey, D. F., Koller, D., Pathak, G. A., Koen, N., Lin, K., Adams, M. J., Rentería, M. E., Feng, Y., Gaziano, J. M., Stein, D. J., Zar, H. J., Campbell, M. L., van Heel, D. A., Trivedi, B., Finer, S., McQuillin, A., Bass, N. & 58 others, Chundru, V. K., Martin, H. C., Huang, Q. Q., Valkovskaya, M., Chu, C. Y., Kanjira, S., Kuo, P. H., Chen, H. C., Tsai, S. J., Liu, Y. L., Kendler, K. S., Peterson, R. E., Cai, N., Fang, Y., Sen, S., Scott, L. J., Burmeister, M., Loos, Ruth, Preuss, M. H., Actkins, K. E. V., Davis, L. K., Uddin, M., Wani, A. H., Wildman, D. E., Aiello, A. E., Ursano, R. J., Kessler, R. C., Kanai, M., Okada, Y., Sakaue, S., Rabinowitz, J. A., Maher, B. S., Uhl, G., Eaton, W., Cruz-Fuentes, C. S., Martinez-Levy, G. A., Campos, A. I., Millwood, I. Y., Chen, Z., Li, L., Wassertheil-Smoller, S., Jiang, Y., Tian, C., Martin, N. G., Mitchell, B. L., Byrne, E. M., Awasthi, S., Coleman, J. R. I., Ripke, S., Sofer, T., Walters, R. G., McIntosh, A. M., Polimanti, R., Dunn, E. C., Stein, M. B., Gelernter, J., Lewis, C. M. & Kuchenbaecker, K., 2024, In: Nature Genetics. 56, 2, p. 222–233

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. E-pub ahead of print

    Unique features of β-cell metabolism are lost in type 2 diabetes

    Muñoz, F., Fex, M., Moritz, Thomas, Mulder, H. & Cataldo Bascunan, Luis Rodrigo, 2024, (E-pub ahead of print) In: Acta Physiologica. e14148.

    Research output: Contribution to journal › Review › Research › peer-review

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