Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk

    U-BIOPRED Study Group, U. S. G., 2023, In: American Journal of Respiratory and Critical Care Medicine. 208, 2, p. 142-154 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle

    Abdelmoez, A. M., Dmytriyeva, O., Zurke, Y. X., Trauelsen, Mette, Marica, A. A., Savikj, M., Smith, J. A. B., Monaco, C., Schwartz, Thue W., Krook, A. & Pillon, N. J., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 324, 4, p. E289-E298 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Genetic variants associated with syncope implicate neural and autonomic processes

    Aegisdottir, H. M., Thorolfsdottir, R. B., Sveinbjornsson, G., Stefansson, O. A., Gunnarsson, B., Tragante, V., Thorleifsson, G., Stefansdottir, L., Thorgeirsson, T. E., Ferkingstad, E., Sulem, P., Norddahl, G., Rutsdottir, G., Banasik, K., Christensen, A. H., Mikkelsen, C., Pedersen, O. B., Brunak, S., Bruun, M. T., Erikstrup, C. & 26 others, Jacobsen, R. L., Nielsen, K. R., Sorensen, E., Frigge, M. L., Hjorleifsson, K. E., Ivarsdottir, E., Helgadottir, A., Gretarsdottir, S., Steinthorsdottir, V., Oddsson, A., Eggertsson, H. P., Halldorsson, G. H., Jones, D. A., Anderson, J. L., Knowlton, K. U., Nadauld, L. D., DBDS Genomic Consortium, D. B. D. S. G. C., Haraldsson, M., Thorgeirsson, G., Bundgård, Henning, Arnar, D. O., Thorsteinsdottir, U., Gudbjartsson, D. F., Ostrowsk, S. R., Holm, H. & Stefansson, K., 2023, In: European Heart Journal. 44, 12, p. 1070–1080 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

    Aglago, E. K., Kim, A., Lin, Y., Qu, C., Evangelou, M., Ren, Y., Morrison, J., Albanes, D., Arndt, V., Barry, E. L., Baurley, J. W., Berndt, S. I., Bien, S. A., Bishop, D. T., Bouras, E., Brenner, H., Buchanan, D. D., Budiarto, A., Carreras-Torres, R., Casey, G. & 80 others, Cenggoro, T. W., Chan, A. T., Chang-Claude, J., Chen, X., Conti, D. V., Devall, M., Díez Obrero, Virginia, Dimou, N., Drew, D., Figueiredo, J. C., Gallinger, S., Giles, G. G., Gruber, S. B., Gsur, A., Gunter, M. J., Hampel, H., Harlid, S., Hidaka, A., Harrison, T. A., Hoffmeister, M., Huyghe, J. R., Jenkins, M. A., Jordahl, K., Joshi, A. D., Kawaguchi, E. S., Keku, T. O., Kundaje, A., Larsson, S. C., Marchand, L. L., Lewinger, J. P., Li, L., Lynch, B. M., Mahesworo, B., Mandic, M., Obón-Santacana, M., Moreno, V., Murphy, N., Nan, H., Nassir, R., Newcomb, P. A., Ogino, S., Ose, J., Pai, R. K., Palmer, J. R., Papadimitriou, N., Pardamean, B., Peoples, A. R., Platz, E. A., Potter, J. D., Prentice, R. L., Rennert, G., Ruiz-Narvaez, E., Sakoda, L. C., Scacheri, P. C., Schmit, S. L., Schoen, R. E., Shcherbina, A., Slattery, M. L., Stern, M. C., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Tian, Y., Ulrich, C. M., van Duijnhoven, F. J., Van Guelpen, B., Visvanathan, K., Vodicka, P., Wang, J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Zemlianskaia, N., Hsu, L., Gauderman, W. J., Peters, U., Tsilidis, K. K. & Campbell, P. T., 2023, In: Cancer Research. 83, 15, p. 2572-2583 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Gene coexpression network analysis reveals perirenal adipose tissue as an important target of prenatal malnutrition in sheep

    Ahmad, S., Drag, Markus Hodal, Salleh, S. M., Cai, Z. & Nielsen, M. O., 2023, In: Physiological Genomics. 55, 9, p. 392-413 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Dried Fruits: Bioactives, Effects on Gut Microbiota, and Possible Health Benefits—An Update

    Alasalvar, C., Chang, S. K., Kris-Etherton, P. M., Sullivan, V. K., Petersen, K. S., Guasch Ferre, Marta & Jenkins, D. J. A., 2023, In: Nutrients. 15, 7, 1611.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling

    Alexopoulou, Flora, Buch-Månson, N., Pedersen, S. L., Vrang, N., Fink, L. N. & Strømgaard, Kristian, 2023, In: Peptides. 168, 7 p., 171063.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Linking Hypothermia and Altered Metabolism with TrkB Activation

    Alitalo, O., González-Hernández, G., Rosenholm, Marko, Kohtala, P., Matsui, N., Müller, H. K., Theilmann, W., Klein, A., Kärkkäinen, O., Rozov, S., Rantamäki, T. & Kohtala, S., 2023, In: ACS Chemical Neuroscience. 14, 17, p. 3212–3225

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]

    Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, Tajes, J. F., Sharma, S., Haid, M., Hong, M., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, Henrik S., Hansen, E., Hansen, T. H., drb459, drb459, Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Ridderstråle, M., Pedersen, Oluf Borbye, Hansen, Torben, Banasik, Karina, Rasmussen, Simon, Brunak, Søren & IMI-DIRECT consortium, I. C., 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Preface: causes of obesity, theories, conjectures and evidence

    Allison, D. B., Sørensen, Thorkild I.A., Hall, K. D. & Speakman, J. R., 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 2 p., 20220200.

    Research output: Contribution to journal › Editorial › Research

  12. Published

    Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity

    Lepola, Mette Andersen, Ängquist, Lars, Bork-Jensen, J., Jonsson, Anna Elisabet, Stinson, Sara, Sandholt, C. H., Thodberg, Malte, Pikkupeura, Laura Maarit, Ongstad, E. L., Grarup, Niels, Astrup, A., Pedersen, Oluf Borbye, Williams, K., Barrès, Romain, Sørensen, Thorkild I.A., Linneberg, Allan René, Grimsby, J., Rhodes, C. J. & Hansen, Torben, 2023, In: Diabetes Care. 46, 5, p. 985–992 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

    Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T. & 83 others, Hoyles, L., Alves, R., Helft, G., Isnard, R., Køber, Lars Valeur, Coelho, L. P., Rouault, C., Gauguier, D., Goetze, Jens P. , Prifti, E., Froguel, P., Alili, R., Galijatovic, E. A. A., Barthelemy, O., Bastard, J. P., Batisse, J. P., Bel-Lassen, P., Berland, M., Bittar, R., Blottière, H., Bosquet, F., Boubrit, R., Bourron, O., Camus, M., Ciangura, C., Collet, J. P., Dietrich, A., Djebbar, M., Doré, A., pjx571, pjx571, Fezeu, L., Fromentin, S., Pons, N., Graine, M., Grünemann, C., Hartemann, A., Hartmann, Bolette, Hornbak, M., Jaqueminet, S., Jørgensen, Niklas Rye, Julienne, H., Justesen, Johanne Marie, Kammer, J., Karup, N., Kozlowski, R., Kuhn, M., Lejard, V., Letunic, I., Levenez, F., Marko, L., Martinez-Gili, L., Massey, R., Maziers, N., Moitinho-Silva, L., Montalescot, G., Neves, A. L., Le Pavin, L. P., Pousset, F., Rodriguez-Martinez, A., Schmidt, S., Schütz, T., Silva, L., Silvain, J., Svendstrup, M., Swartz, T. D., Vanduyvenboden, T., Verger, E. O., Walther, S., Zucker, J. D., Bäckhed, F., drb459, drb459, Hansen, Torben, Oppert, J. M., Blüher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M. M., Stumvoll, M., Pedersen, Oluf Borbye, Ehrlich, S. D., Clément, K. & Dumas, M. E., 2023, In: Nature Communications. 14, 18 p., 5843.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Approaches to addressing the rise in obesity levels

    Apovian, C. M., Guo, X. R., Hawley, J. A., Karmali, S., Loos, Ruth & Waterlander, W. E., 2023, In: Nature Reviews Endocrinology. 19, p. 76-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

    Armour, Sarah Louise, Frueh, A., Chibalina, M. V., Dou, H., Argemi Muntadas, Lidia, Hamilton, Alexander, Katzilieris Petras, Georgios, Carmeliet, P., Davies, B., Moritz, Thomas, Eliasson, L., Rorsman, P. & Knudsen, Jakob Grunnet, 2023, In: Diabetes. 72, 10, p. 1446-1459 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Redeeming the Past, Present, and Future

    Arnold, Ken, 2023, In: Centaurus. 65, 2, p. 417-425 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise

    Ashcroft, Stephen Paul, Jepsen, Sara Lind, Ehrlich, Amy M, Treebak, Jonas Thue, Holst, Jens Juul & Zierath, Juleen R, 2023, In: STAR Protocols. 4, 1, 11 p., 101985.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery

    Aukan, M. I., Skårvold, S., Brandsaeter, I. Ø., Rehfeld, Jens Frederik, Holst, Jens Juul, Nymo, S., Coutinho, S. & Martins, C., 2023, In: Obesity. 31, 2, p. 399-411 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

    Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

    Bacos, K., Perfilyev, A., Karagiannopoulos, A., Cowan, E., Ofori, J. K., Bertonnier-Brouty, L., Rönn, T., Lindqvist, A., Luan, C., Ruhrmann, S., Ngara, M., Nilsson, Å., Gheibi, S., Lyons, C. L., Lagerstedt, J. O., Barghouth, M., Esguerra, J. L. S., Volkov, P., Fex, M., Mulder, H. & 7 others, Wierup, N., Krus, U., Artner, I., Eliasson, L., Prasad, R. B., Cataldo Bascunan, Luis Rodrigo & Ling, C., 2023, In: Journal of Clinical Investigation. 133, 4, 17 p., e163612.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue

    Bager Christensen, I., Blom, Ida, Dohlmann, T. L., Finger, Fabian Michael, Helge, Jørn Wulff, Gerhart-Hines, Zach, Dela, Flemming & Larsen, Steen, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 10, p. e916-e922 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A Novel Homozygous Nonsense Variant in the DΥM Underlies Dyggve-Melchior-Clausen Syndrome in Large Consanguineous Family

    Bakar, A., Shams, S., Bibi, N., Ullah, A., Ahmad, W., Jelani, M., Muthaffar, O. Y., Abdulkareem, A. A., Abujamel, T. S., Haque, A., Naseer, M. I. & Khan, B., 2023, In: Genes. 14, 14 p., 510.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

    Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

    Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 others, Allard, C., Groleau, M., Kuulasmaa, T., Leirer, D. J., White, F., Jacques, P. É., Cheng, H., Hao, K., Andreassen, O. A., Åsvold, B. O., Atalay, M., Bhatta, L., Bouchard, L., Brumpton, B. M., Brunak, Søren, Bybjerg-Grauholm, J., Ebbing, C., Elliott, P., pjx571, pjx571, Erikstrup, C., Estarlich, M., Franks, S., Gaillard, R., Geller, F., Grove, J., Hougaard, D. M., Kajantie, E., Morgen, C. S., Nohr, E. A., Nyegaard, Mette, Palmer, C. N. A., Pedersen, Ole Birger Vesterager, Rivadeneira, F., Sebert, S., Shields, B. M., Stoltenberg, C., Surakka, I., Thørner, L. W., Ullum, H., Vaarasmaki, M., Vilhjalmsson, B. J., Willer, C. J., Lakka, T. A., Gybel-Brask, D., Bustamante, M., Hansen, Torben, Pearson, E. R., Reynolds, R. M., Ostrowski, Sisse Rye, Pennell, C. E., Jaddoe, V. W. V., Felix, J. F., Hattersley, A. T., Melbye, M., Lawlor, D. A., Hveem, K., Werge, Thomas, Nielsen, Henriette Svarre, Magnus, P., Evans, D. M., Jacobsson, B., Järvelin, M. R., Zhang, G., Hivert, M. F., Johansson, S., Freathy, R. M., Feenstra, B. & Njølstad, P. R., 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading

    Berg, P., Jensen, T., Andersen, J. F., Svendsen, S. L., Modvig, Ida Marie, Wang, T., Frische, S., Chow, B. K. C., Malte, H., Holst, Jens Juul, Sørensen, M. V. & Leipziger, J., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 8, p. 1329-1342 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Variants in EFCAB7 underlie nonsyndromic postaxial polydactyly

    Bilal, M., Khan, H., Khan, M. J., Haack, T. B., Buchert, R., Liaqat, K., Ullah, K., Ahmed, S., Bharadwaj, T., Acharya, A., Peralta, S., Najumuddin, Ali, H., Hasni, M. S., Schrauwen, I., Ullah, A., Ahmad, W. & Leal, S. M., 2023, In: European Journal of Human Genetics. 31, 11, p. 1270-1274

    Research output: Contribution to journal › Journal article › Research › peer-review

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