- 2023
- Published
Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system
Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide
Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092Research output: Contribution to journal › Review › Research › peer-review
- Published
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations
Gerhart-Hines, Zach & Loos, Ruth, 2023, In: Current Opinion in Genetics and Development. 83, 102117.Research output: Contribution to journal › Editorial › Research
- Published
A comprehensive map of human glucokinase variant activity
Gersing, S., Cagiada, Matteo, Gebbia, M., Gjesing, A. P., Coté, A. G., Seesankar, G., Li, R., Tabet, D., Weile, J., Stein, Amelie, Gloyn, A. L., Hansen, Torben, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Genome Biology. 24, 1, 23 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine
Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of topical corticosteroid vs. tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis - a randomized controlled study
Gether, L., Storgaard, H., Kezic, S., Jakasa, I., Hartmann, Bolette, Skov-Jeppesen, Kirsa, Holst, Jens Juul, Pedersen, A. J., Forman, Julie Lyng, van Hall, Gerrit, Sørensen, O. E., Skov, Lone, Røpke, Mads Almose, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, 2023, In: Allergy. 78, 7, p. 1964-1979 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes
Gheibi, S., Cataldo Bascunan, Luis Rodrigo, Hamilton, Alexander, Huang, M., Kalamajski, S., Fex, M. & Mulder, H., 2023, In: Diabetes. 72, 4, p. 455-466 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Portfolio Diet Score and Risk of Cardiovascular Disease: Findings From 3 Prospective Cohort Studies
Glenn, A. J., Guasch Ferre, Marta, Malik, V. S., Kendall, C. W. C., Manson, J. A. E., Rimm, E. B., Willett, W. C., Sun, Q., Jenkins, D. J. A., Hu, F. B. & Sievenpiper, J. L., 2023, In: Circulation. 148, 22, p. 1750-1763 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative differences in synthetic gut microbial inoculums do not affect the final stabilized in vitro community compositions
Gnanasekaran, Thiyagarajan, Sarathi, Arjun, Fang, Q., Azarm, A., Geraldo, Juliana Assis, Nigro, E. & Arumugam, Mani, 2023, In: mSystems. 8, 4, 16 p., e0124922.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dietary regulation of LEAP2 depends on meal composition in mice
Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα
Griem-Krey, Nane, Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., Nagaraja, R. Y., De Silva, T. M., Sobey, C. G., Cheng, H. C., Orset, C., Vivien, D., Lambertsen, K. L., Clarkson, A. N. & Wellendorph, Petrine, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 8, p. 1419-1434Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice
Griepke, S., Trauelsen, Mette, Nilsson, M. D., Hansen, J., Steffensen, L. B., Schwartz, Thue W. & Ketelhuth, D. F. J., 2023, In: Cells. 12, 21, 14 p., 2580.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From Mausoleum to Living Room. Practicing Metabolic Carpentry in the Museum
Grünfeld, Martin, Bencard, Adam & Whiteley, Louise, 2023, In: Centaurus. 65, 2, p. 387-416 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Nut Consumption on Blood Lipids and Lipoproteins: A Comprehensive Literature Update
Guasch Ferre, Marta, Tessier, A. J., Petersen, K. S., Sapp, P. A., Tapsell, L. C., Salas-Salvadó, J., Ros, E. & Kris-Etherton, P. M., 2023, In: Nutrients. 15, 3, 20 p., 596.Research output: Contribution to journal › Review › Research › peer-review
- Published
Are SADI-S and BPD/DS bariatric procedures identical twins or distant relatives? – A case report
Guimarães, M., Pereira, A. M., Pereira, S. S., Almeida, R., Lobato, C. B., Hartmann, Bolette, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Obesity Research and Clinical Practice. 17, 2, p. 166-170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of genetic variants associated with a wide spectrum of phenotypes clinically diagnosed as Sanfilippo and Morquio syndromes using whole genome sequencing
Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña Lozano, Elionora, Thuesen, Anne Cathrine Baun, Gjesing, A. P., Hussain, M., Tufail, M., Saqib, M., Afshan, K. & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 14 p., 1254909.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing
Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña, E., Thuesen, Anne Cathrine Baun, Hussain, M., Stæger, Frederik Filip Vinggaard, Gjesing, A. P., Albrechtsen, Anders & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 13 p., 1128850.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., Marasa, M. & 60 others, , 2023, In: Nature Communications. 14, 8 p., 7836.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes
Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, Jens, Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel homozygous nonsense mutation in NECTIN4 gene in a Pakistani family with ectodermal dysplasia syndactyly syndrome 1
Hajra, B., Abdullah, Bibi, N., Syed, F., Ullah, A., Ahmad, W. & Umm-e-Kalsoom, 2023, In: Anais Brasileiros de Dermatologia. 98, 5, p. 580-586 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut Microbiota Contribution to Weight-Independent Glycemic Improvements after Gastric Bypass Surgery
Hankir, M. K., Kovatcheva-Datchary, P., Springer, R., Hoffmann, A., Vogel, J., Seyfried, F. & Arora, Tulika, 2023, In: Microbiology Spectrum. 11, 3, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birthweight is associated with clinical characteristics in people with recently diagnosed type 2 diabetes
Hansen, A. L., Thomsen, R. W., Brøns, C., Svane, H. M. L., Jensen, Rasmus Tanderup, Lepola, Mette Andersen, Hansen, Torben, Nielsen, J. S., Vestergaard, P., Højlund, K., Jessen, N., Olsen, M. H., Sørensen, H. T. & Vaag, Allan, 2023, In: Diabetologia. 66, p. 1680-1692 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial
Hansen, C. D., Gram-Kampmann, E-M., Hansen, J. K., Hugger, M. B., Madsen, B. S., Jensen, J. M., Olesen, S., Torp, N., Rasmussen, D. N., Kjærgaard, M., Johansen, S., Lindvig, K. P., Andersen, P., Thorhauge, K. H., Brønd, J. C., Hermann, P., Beck-Nielsen, H., Detlefsen, S., Hansen, T., Højlund, K. & 3 others, , 2023, In: Annals of Internal Medicine. 176, 1, p. 10-21 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cold Exposure and Oral Delivery of GLP-1R Agonists by an Engineered Probiotic Yeast Strain Have Antiobesity Effects in Mice
Hedin, K. A., Zhang, H., Kruse, V., Rees, V. E., Bäckhed, F., Greiner, T. U., Vazquez-Uribe, R. & Sommer, M. O. A., 2023, In: ACS Synthetic Biology. 12, 11, p. 3433-3442 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The social origins of obesity within and across generations
Hemmingsson, E., Nowicka, P., Ulijaszek, S. & Sørensen, Thorkild I.A., 2023, In: Obesity Reviews. 24, 1, 11 p., e13514.Research output: Contribution to journal › Review › Research › peer-review
- Published
Hyperhidrosis is associated with sleep disturbances, daytime tiredness, stress, and depression: A retrospective cohort study from the Danish Blood Donor Study
Henning, M., Ibler, Kristina Sophie, Loft, I., Jennum, Poul, Didriksen, M., Ullum, H., Erikstrup, C., Nielsen, K., Bruun, M. T., Hjalgrim, Henrik, Sørensen, E., Dinh, K., Thørner, L. W., Jemec, Gregor & Pedersen, Oluf Borbye, 2023, In: Journal of the American Academy of Dermatology. 88, 1, p. 196-197Research output: Contribution to journal › Comment/debate › Research
- Published
Muscle miRNAs are influenced by sex at baseline and in response to exercise
Hiam, D., Landen, S., Jacques, M., Voisin, S., Lamon, S. & Eynon, N., 2023, In: BMC Biology. 21, 14 p., 273.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cord blood FGF-21 and GDF-15 levels are affected by maternal exposure to moderate to severe anemia and malaria
Hjort, Line, Albrechtsen, Nicolai Jacob Wewer, Minja, D., Rasmussen, C., Møller, S. L., Lusingu, J., Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Schmiegelow, Christentze & Grunnet, Louise Groth, 2023, In: Journal of the Endocrine Society. 7, 10, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted Analysis of Phosphorylated Metabolites in Biological Samples by HILIC–LC–MS
Hodek, O., Jiang, W. & Moritz, Thomas, 2023, In: LC-GC North America. 41, 8, p. 354-355 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry
Hodek, O., Henderson, John David, Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2023, In: Journal of Chromatography - B. 1222, 9 p., 123719.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FK506-Binding Protein 2 Participates in Proinsulin Folding
Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, , 2023, In: Biomolecules. 13, 1, 20 p., 152.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ketone monoester increases circulating levels of LEAP2 and decreases appetite in healthy men
Holm, Stephanie Kjærulff, Vestergaard, E. T., Zubanovic, N. B., Byberg, Sarah, Clemmensen, Christoffer, Holst, Birgitte & Thomsen, H. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 7, p. :2023–2027Research output: Contribution to journal › Letter › Research › peer-review
- Published
Secretion and Impact of Gut Hormones in Obesity and Diabetes
Holst, Jens Juul, 2023, Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Elsevier, Vol. 6. p. 543-550 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glucagon 100 years. Important, but still enigmatic
Holst, Jens Juul, 2023, In: Peptides. 161, 6 p., 170942.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin-based therapy of metabolic disease
Holst, Jens Juul, 2023, In: Danish Medical Journal. 70, 1, A10220597.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores
Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A. C., Carson, A. P., Haring, B., Mitchel, B. D., Psaty, B. M., Jaeger, B. C., Gu, C. C., Kooperberg, C., Levy, D., Lloyd-Jones, D., Choi, E., Brody, J. A., Smith, J. A., Rotter, J. I., Moll, M. & 18 others, , 2023, medRxiv, 41 p.Research output: Working paper › Preprint › Research
- Published
An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents
Huang, Yun, Stinson, Sara, Juel, H. B., Lund, M. A. V., Holm, Louise Aas, Fonvig, Cilius Esmann, Nielsen, T., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, M., Chabanova, E., Thomsen, Henrik S., Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes
Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, , 2023, In: Diabetologia. 66, p. 1273-1288 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938–1963
Hussey, Kristin D., 2023, In: History and Philosophy of the Life Sciences. 45, 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Z-Time: Making and feeling time in the chronobiological laboratory
Hussey, Kristin D., 2023, (E-pub ahead of print) In: Time & Society.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies
India-Aldana, S., Yao, M., Midya, V., Colicino, E., Chatzi, L., Chu, J., Gennings, C., Jones, D. P., Loos, Ruth, Setiawan, V. W., Smith, M. R., Walker, R. W., Barupal, D., Walker, D. I. & Valvi, D., 2023, In: Current Pollution Reports. 9, p. 510-568Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes
Ingersen, Arthur, Schmücker, Malte, Alexandersen, C., Graungaard, B., Thorngreen, T., Borch, Jacob, Holst, Jens Juul, Helge, Jørn Wulff & Dela, Flemming, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2798–2811Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial
Israelsen, M., Madsen, B. S., Torp, N., Johansen, S., Hansen, C. D., Detlefsen, S., Andersen, P., Hansen, J. K., Lindvig, K. P., Rasmussen, D. N., Thorhauge, K. H., Kjærgaard, M., Karsdal, M., Hansen, Torben, Arumugam, Mani, Trebicka, J., Thiele, M., Krag, A. & GALAXY, G., 2023, In: The Lancet Gastroenterology and Hepatology. 8, 6, p. 523-532 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training
Jacques, M., Landen, S., Romero, J. A., Hiam, D., Schittenhelm, R. B., Hanchapola, I., Shah, A. D., Voisin, S. & Eynon, N., 2023, In: FASEB Journal. 37, 10, 18 p., e23184.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing
Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, , 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function
Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification
Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.Research output: Contribution to journal › Review › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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