Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2023
  2. Published

    The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

    Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, Ruth, Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher-Hoch, S. P., Ordoñez, M. L., Meigs, J., Baier, L. J., González-Villalpando, C., González-Villalpando, M. E., Orozco, L., García-García, L. & Mexican Biobank, M. B., 2023, In: Diabetologia. 66, p. 1273-1288 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938–1963

    Hussey, Kristin D., 2023, In: History and Philosophy of the Life Sciences. 45, 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies

    India-Aldana, S., Yao, M., Midya, V., Colicino, E., Chatzi, L., Chu, J., Gennings, C., Jones, D. P., Loos, Ruth, Setiawan, V. W., Smith, M. R., Walker, R. W., Barupal, D., Walker, D. I. & Valvi, D., 2023, In: Current Pollution Reports. 9, p. 510-568

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes

    Ingersen, Arthur, Schmücker, Malte, Alexandersen, C., Graungaard, B., Thorngreen, T., Borch, Jacob, Holst, Jens Juul, Helge, Jørn Wulff & Dela, Flemming, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2798–2811

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial

    Israelsen, M., Madsen, B. S., Torp, N., Johansen, S., Hansen, C. D., Detlefsen, S., Andersen, P., Hansen, J. K., Lindvig, K. P., Rasmussen, D. N., Thorhauge, K. H., Kjærgaard, M., Karsdal, M., Hansen, Torben, Arumugam, Mani, Trebicka, J., Thiele, M., Krag, A. & GALAXY, G., 2023, In: The Lancet Gastroenterology and Hepatology. 8, 6, p. 523-532 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training

    Jacques, M., Landen, S., Romero, J. A., Hiam, D., Schittenhelm, R. B., Hanchapola, I., Shah, A. D., Voisin, S. & Eynon, N., 2023, In: FASEB Journal. 37, 10, 18 p., e23184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing

    Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, Kardia, S. L. R., Lewis, J. P., Loos, Ruth, Ma, X., Machiela, M. J., Mack, T. M., Mathias, R. A., Mitchell, B. D., Mychaleckyj, J. C., North, K., Pankratz, N., Peyser, P. A., Preuss, M. H., Psaty, B., Raffield, L. M., Vasan, R. S., Redline, S., Rich, S. S., Rotter, J. I., Silverman, E. K., Smith, J. A., Smith, A. P., Taub, M., Taylor, K. D., Yun, J., Li, Y., Desai, P., Bick, A. G., Reiner, A. P., Scheet, P. & Auer, P. L., 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification

    Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

    Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

    Jujic, A., Godina, C., Belting, M., Melander, O., Holst, Jens Juul, Ahlqvist, E., Gomez, M. F., Nilsson, P. M., Jernstrom, H. & Magnusson, M., 2023, In: Scientific Reports. 13, 1, 11 p., 382.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis

    Jørgensen, N. T., Erichsen, T. M., Jørgensen, M. B., Idorn, T., Feldt-Rasmussen, Bo, Holst, Jens Juul, Feldt-Rasmussen, Ulla & Klose, M., 2023, In: Pituitary. 26, p. 152–163

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude

    Kadalayil, L., Alam, M. Z., White, C. H., Ghantous, A., Walton, E., Gruzieva, O., Merid, S. K., Kumar, A., Roy, R. P., Solomon, O., Huen, K., Eskenazi, B., Rzehak, P., Grote, V., Langhendries, J. P., Verduci, E., Ferre, N., Gruszfeld, D., Gao, L., Guan, W. & 83 others, Zeng, X., Schisterman, E. F., Dou, J. F., Bakulski, K. M., Feinberg, J. I., Soomro, M. H., Pesce, G., Baiz, N., Isaevska, E., Plusquin, M., Vafeiadi, M., Roumeliotaki, T., Langie, S. A. S., Standaert, A., Allard, C., Perron, P., Bouchard, L., van Meel, E. R., Felix, J. F., Jaddoe, V. W. V., Yousefi, P. D., Ramlau-Hansen, C. H., Relton, C. L., Tobi, E. W., Starling, A. P., Yang, I. V., Llambrich, M., Santorelli, G., Lepeule, J., Salas, L. A., Bustamante, M., Ewart, S. L., Zhang, H., Karmaus, W., Röder, S., Zenclussen, A. C., Jin, J., Nystad, W., Page, C. M., Magnus, M., Jima, D. D., Hoyo, C., Maguire, R. L., Kvist, T., Czamara, D., Räikkönen, K., Gong, T., Ullemar, V., Rifas-Shiman, S. L., Oken, E., Almqvist, C., Karlsson, R., Lahti, J., Murphy, S. K., Håberg, S. E., London, S., Herberth, G., Arshad, H., Sunyer, J., Grazuleviciene, R., Dabelea, D., Steegers-Theunissen, R. P. M., Nohr, E. A., Sørensen, Thorkild I.A., Duijts, L., Hivert, M. F., Nelen, V., Popovic, M., Kogevinas, M., Nawrot, T. S., Herceg, Z., Annesi-Maesano, I., Fallin, M. D., Yeung, E., Breton, C. V., Koletzko, B., Holland, N., Wiemels, J. L., Melén, E., Sharp, G. C., Silver, M. J., Rezwan, F. I. & Holloway, J. W., 2023, In: Clinical Epigenetics. 15, 23 p., 148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A second update on mapping the human genetic architecture of COVID-19

    Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, Hjalgrim, Henrik, Admin team lead, A. T. L., Admin team member, A. T. M., Analysis team lead, A. T. L., Analysis team member, A. T. M., Data collection lead, D. C. L., Data collection member, D. C. M., Manuscript analysis team lead, M. A. T. L., Manuscript analysis team members: Mendelian randomization, M. A. T. M. M. R., Manuscript analysis team members: methods development, M. A. T. M. M. D., Manuscript analysis team members: phenome-wide association study, M. A. T. M. P. A. S., Manuscript analysis team members: principal component projection, gene prioritization, M. A. T. M. P. C. P. G. P., Project management lead, P. M. L., Scientific communication lead, S. C. L., Scientific communication member, S. C. M., Writing group lead, W. G. L., Writing group member, W. G. M., 23andMe, 2., Adolescent brain and cognitive development study, A. B. A. C. D. S., Analysis group, A. G., Armenia_Covid-19hg, A., Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, A. O. T. I. O. C. F. I. A. G. F. O. T. S. O. T. C. O. C. I. W. S. A. P. S., Avon Longitudinal Study of Parents and Children (ALSPAC), A. L. S. O. P. A. C. (., BelCovid, B., Biobanque Quebec COVID19, B. Q. C., BioVU, B., Bonn Study of COVID-19 Genetics, B. S. O. C. G., CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, C. H. C. H. H. G. S. D., Colorado Center for Personalized Medicine—CCPM, C. C. F. P. M., COMRI/Virology Study, C. S., Covid19 Ioannina Biobank, C. I. B., COVID19-Host(a)ge, C., Covid19hg-CL, C., Danish COVID-19 Genomic Consortium, D. C. G. C., Egypt hgCOVID hub, E. H. H., EraCORE, E., FinnGen, F., French hgCOVID, F. H., GCAT. Genomes For Life, G. G. F. L., Genes & Health, G. &. H., Genetic influences on severity of COVID-19 illness in Korea, G. I. O. S. O. C. I. I. K., GenOMICC, G., Genotek COVID-19 study, G. C. S., Helix Exome+ COVID-19 Phenotypes, H. E. C. P., Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, H. G. F. F. C. S. A. O. I. W. I. P., Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, H. G. I. C. C. O. M. A. F. M., Japan Coronavirus Taskforce, J. C. T., Japan NCGM-COVID19, J. N., Jordan COVID-19 Host Genomics Initiative (JCHGI), J. C. H. G. I. (., Leadership, L., Lung eQTL Consortium, L. E. C., Mass General Brigham—Host Vulnerability to COVID-19, M. G. B. V. T. C., MexGen-COVID, M., Pa-COVID-19, P., Project management group, P. M. G., Project management support, P. M. S., Qatar Genome Program, Q. G. P., SARS-CoV-2 and Host Genome sequencing, S. A. H. G. S., Scientific communication group, S. C. G., Search for Genomic Markers Predicting the Severity of the response to COVID-19, S. F. G. M. P. T. S. O. T. R. T. C., Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), S. C. T. U. R. O. H. G. O. C. (., The Danish Blood Donor Study, T. D. B. D. S., The Genetic Predisposition to severe COVID-19, T. G. P. T. S. C., Tirschenreuth Study (TiKoco), T. S. (., UCLA Precision Health COVID-19 Host Genomics Biobank, U. P. H. C. H. G. B., UK Biobank, U. B., Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), V. I. I. R. G. A. S. O. S. I. (. S., Website development, W. D., Writing Group, W. G. & The COVID-19 Host Genetics Initiative, T. C. H. G. I., 2023, In: Nature. 621, 7977, p. E7-E26 23 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  16. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Gut bacterial metabolism contributes to host global purine homeostasis

    Kasahara, K., Kerby, R. L., Zhang, Q., Pradhan, M., Mehrabian, M., Lusis, A. J., Bergström, G., Bäckhed, F. & Rey, F. E., 2023, In: Cell Host and Microbe. 31, 6, p. 1038-1053.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Maturity-onset diabetes of the young og graviditet

    Kauffmann, A., Jørgensen, I. L., Thuesen, Anne Cathrine Baun, Ringholm, Lene, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben & Damm, Peter, 2023, In: Ugeskrift for Laeger. 185, 21, V02230067.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Arrest of movement induced by Pedunculopontine-stimulation obstructs hippocampal theta rhythm

    Kaur, Jaspreet, Komi, Salif Axel, Dmytriyeva, O., Houser, Grace Anne, Bonfils, M. C. A. & Berg, Rune W., 2023, bioRxiv, p. 1-14, 14 p.

    Research output: Working paperPreprintResearch

  20. Published

    Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

    Kennedy, K. M., de Goffau, M. C., Perez-Muñoz, M. E., Arrieta, M. C., Bäckhed, F., Bork, P., Braun, T., Bushman, F. D., Dore, J., de Vos, W. M., Earl, A. M., Eisen, J. A., Elovitz, M. A., Ganal-Vonarburg, S. C., Gänzle, M. G., Garrett, W. S., Hall, L. J., Hornef, M. W., Huttenhower, C., Konnikova, L. & 26 others, Lebeer, S., Macpherson, A. J., Massey, R. C., McHardy, A. C., Koren, O., Lawley, T. D., Ley, R. E., O’Mahony, L., O’Toole, P. W., Pamer, E. G., Parkhill, J., Raes, J., Rattei, T., Salonen, A., Segal, E., Segata, N., Shanahan, F., Sloboda, D. M., Smith, G. C. S., Sokol, H., Spector, T. D., Surette, M. G., Tannock, G. W., Walker, A. W., Yassour, M. & Walter, J., 2023, In: Nature. 613, 7945, p. 639-649 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Synergy and oxygen adaptation for development of next-generation probiotics

    Khan, M. T., Dwibedi, C., Sundh, D., Pradhan, M., Kraft, J. D., Caesar, R., Tremaroli, V., Lorentzon, M. & Bäckhed, F., 2023, In: Nature. 620, p. 381-385

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women: A Prospective Cohort Study

    Kianersi, S., Liu, Y., Guasch Ferre, Marta, Redline, S., Schernhammer, E., Sun, Q. & Huang, T., 2023, In: Annals of Internal Medicine. 176, 10, p. 1330-1339 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

    Kiryluk, K., Sanchez-Rodriguez, E., Zhou, X. J., Zanoni, F., Liu, L., Mladkova, N., Khan, A., Marasa, M., Zhang, J. Y., Balderes, O., Sanna-Cherchi, S., Bomback, A. S., Canetta, P. A., Appel, G. B., Radhakrishnan, J., Trimarchi, H., Sprangers, B., Cattran, D. C., Reich, H., Pei, Y. & 168 others, Ravani, P., Galesic, K., Maixnerova, D., Tesar, V., Stengel, B., Metzger, M., Canaud, G., Maillard, N., Berthoux, F., Berthelot, L., Pillebout, E., Monteiro, R., Nelson, R., Wyatt, R. J., Smoyer, W., Mahan, J., Samhar, A. A., Hidalgo, G., Quiroga, A., Weng, P., Sreedharan, R., Selewski, D., Davis, K., Kallash, M., Vasylyeva, T. L., Rheault, M., Chishti, A., Ranch, D., Wenderfer, S. E., Samsonov, D., Claes, D. J., Akchurin, O., Goumenos, D., Stangou, M., Nagy, J., Kovacs, T., Fiaccadori, E., Amoroso, A., Barlassina, C., Cusi, D., Del Vecchio, L., Battaglia, G. G., Bodria, M., Boer, E., Bono, L., Boscutti, G., Caridi, G., Lugani, F., Ghiggeri, G. M., Coppo, R., Peruzzi, L., Esposito, V., Esposito, C., Feriozzi, S., Polci, R., Frasca, G., Galliani, M., Garozzo, M., Mitrotti, A., Gesualdo, L., Granata, S., Zaza, G., Londrino, F., Magistroni, R., Pisani, I., Magnano, A., Marcantoni, C., Messa, P., Mignani, R., Pani, A., Ponticelli, C., Roccatello, D., Salvadori, M., Salvi, E., Santoro, D., Gembillo, G., Savoldi, S., Spotti, D., Zamboli, P., Izzi, C., Alberici, F., Delbarba, E., Florczak, M., Krata, N., Mucha, K., Pączek, L., Niemczyk, S., Moszczuk, B., Pańczyk-Tomaszewska, M., Mizerska-Wasiak, M., Perkowska-Ptasińska, A., Bączkowska, T., Durlik, M., Pawlaczyk, K., Sikora, P., Zaniew, M., Kaminska, D., Krajewska, M., Kuzmiuk-Glembin, I., Heleniak, Z., Bullo-Piontecka, B., Liberek, T., Dębska-Slizien, A., Hryszko, T., Materna-Kiryluk, A., Miklaszewska, M., Szczepańska, M., Dyga, K., Machura, E., Siniewicz-Luzeńczyk, K., Pawlak-Bratkowska, M., Tkaczyk, M., Runowski, D., Kwella, N., Drożdż, D., Habura, I., Kronenberg, F., Prikhodina, L., van Heel, D., Fontaine, B., Cotsapas, C., Wijmenga, C., Franke, A., Annese, V., Gregersen, P. K., Parameswaran, S., Weirauch, M., Kottyan, L., Harley, J. B., Suzuki, H., Narita, I., Goto, S., Lee, H., Kim, D. K., Kim, Y. S., Park, J. H., Cho, B. L., Choi, M., Van Wijk, A., Huerta, A., Ars, E., Ballarin, J., Lundberg, S., Vogt, B., Mani, L. Y., Caliskan, Y., Barratt, J., Abeygunaratne, T., Kalra, P. A., Gale, D. P., Panzer, U., Rauen, T., Floege, J., Schlosser, P., Ekici, A. B., Eckardt, K. U., Chen, N., Xie, J., Lifton, R. P., Loos, Ruth, Kenny, E. E., Ionita-Laza, I., Köttgen, A., Julian, B. A., Novak, J., Scolari, F., Zhang, H. & Gharavi, A. G., 2023, In: Nature Genetics. 55, 7, p. 1091-1105 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Discrepancy between predicted and measured exercise intensity for eliciting the maximal rate of lipid oxidation

    Kittrell, H. D., DiMenna, F. J., Arad, A. D., Oh, W., Hofer, I., Walker, R. W., Loos, Ruth, Albu, J. B. & Nadkarni, G. N., 2023, In: Nutrition, Metabolism and Cardiovascular Diseases. 33, 11, p. 2189-2198

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol

    Kjeldsen, S. A. S., Richter, M. M., Jensen, N. J., Nilsson, M. S. D., Heinz, N., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, M. P., Madsbad, S., Vilstrup, H., Schiødt, F. V., Møller, A., Nørgaard, K., Schmidt, S., Rashu, E. B., Gluud, L. L., Haugaard, S. B., Holst, J. J., Rungby, J. & 1 others, Albrechtsen, Nicolai Jacob Wewer, 2023, In: Peptides. 161, 10 p., 170938.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

    Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Cross-species comparison of pregnancy-induced GDF15

    Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

    Kneppers, A., Ben Larbi, S., Theret, M., Saugues, A., Dabadie, C., Gsaier, L., Ferry, A., Rhein, P., Gondin, J., Sakamoto, Kei & Mounier, R., 2023, In: iScience. 26, 12, 17 p., 108343.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity

    Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J. V., Nielsen, J. S., Højlund, K., Beck-Nielsen, H., Jensen, T. S., Andersen, H., Vestergaard, P., Jessen, N., Olsen, M. H., Hansen, Torben, Brøns, C., Vaag, Allan, Sørensen, H. T. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 8, p. 1546-1555 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Atorvastatin for patients with cirrhosis. A randomized, placebo-controlled trial

    Kronborg, T. M., Schierwagen, R., Trošt, K., Gao, Q., Moritz, Thomas, Bendtsen, Flemming, Gantzel, R. H., Andersen, M. L., Teisner, A. S., Grønbæk, H., Hobolth, L., Møller, Søren, Trebicka, J. & Kimer, N., 2023, In: Hepatology Communications. 7, 12, 11 p., e0332.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

    Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Corrêa, I. R., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., den Hoed, M., Shmeliov, A., den Hoed, M., Loos, Ruth, Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njølstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, Tune H, Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I. & van Duijn, C. M., 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Sex differences in muscle protein expression and DNA methylation in response to exercise training

    Landen, S., Jacques, M., Hiam, D., Alvarez-Romero, J., Schittenhelm, R. B., Shah, A. D., Huang, C., Steele, J. R., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Lamon, S., Voisin, S. & Eynon, N., 2023, In: Biology of Sex Differences. 14, 20 p., 56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

    Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials

    Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue

    Larsen, Jeppe Kjærgaard, Kruse, R., Sahebekhtiari, N., Moreno Justicia, Roger, Jorba, G. G., Petersen, M. H., de Almeida, M. E., Ørtenblad, N., Deshmukh, Atul Shahaji & Højlund, K., 2023, In: Science Advances. 9, 48, 16 p., eadi7548.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Birth weight, childhood body mass index, and risk of diverticular disease in adulthood

    Laursen, A. S. D., Jensen, B. W., Strate, L. L., Sørensen, Thorkild I.A., Baker, J. L. & Sørensen, H. T., 2023, In: International Journal of Obesity. 47, p. 207–214 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development

    Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Editorial: Healthy adipose tissue expansion

    Lee, K. Y., Emanuelli, Brice & Ussar, S., 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1287533.

    Research output: Contribution to journalEditorialResearch

  44. Published

    Ancestral diversity in lipoprotein(a) studies helps address evidence gaps

    Lee, M. P., Dimos, S. F., Raffield, L. M., Wang, Z., Ballou, A. F., Downie, C. G., Arehart, C. H., Correa, A., De Vries, P. S., Du, Z., Gignoux, C. R., Gordon-Larsen, P., Guo, X., Haessler, J., Howard, A. G., Hu, Y., Kassahun, H., Kent, S. T., Lopez, J. A. G., Monda, K. L. & 14 others, North, K. E., Peters, U., Preuss, M. H., Rich, S. S., Rhodes, S. L., Yao, J., Yarosh, R., Tsai, M. Y., Rotter, J. I., Kooperberg, C. L., Loos, Ruth, Ballantyne, C., Avery, C. L. & Graff, M., 2023, In: Open Heart. 10, 2, 11 p., e002382.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

    Legaard, G. E., Lyngbæk, M. P. P., Almdal, T. P., Karstoft, K., Bennetsen, S. L., Feineis, C. S., Nielsen, N. S., Durrer, C. G., Liebetrau, B., Nystrup, U., Østergaard, M., Thomsen, K., Trinh, B., Solomon, T. P. J., Van Hall, G., Brønd, J. C., Holst, J. J., Hartmann, B., Christensen, R., Pedersen, B. K. & 1 others, Ried-Larsen, M., 2023, In: Nature Metabolism. 5, p. 880–895

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases

    Lehtimäki, J., Gupta, S., Hjelmsø, M., Shah, S., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Soverini, M., Li, Xuan Ji, Russel, J., Trivedi, Urvish, Brix, S., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Bisgaard, H., Sørensen, Søren Johannes & Stokholm, Jakob, 2023, In: Clinical and Experimental Allergy. 53, 12, p. 1268-1278 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published
  48. Published
  49. Published

    The effect of traditional diet on glucose homeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: A randomized crossover study

    Lewis, Jack Ivor, Lind, M. V., Møller, G., Hansen, Torben, Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., Stark, K. D., Bjerregaard, P., Jørgensen, M. E. & Lauritzen, Lotte, 2023, In: British Journal of Nutrition. 130, 11, p. 1871-1884

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside

    Li, Q., Jiang, Xuye, Zhou, Y., Gu, Y., Ding, Y., Luo, J., Pang, N., Sun, Y., Pei, L., Pan, J., Gao, M., Ma, S., Xiao, Y., Hu, D., Wu, F. & Yang, L., 2023, In: International Journal of Molecular Sciences. 24, 12, 19 p., 10015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

    Li, X., Chen, H., Selvaraj, M. S., Van Buren, E., Zhou, H., Wang, Y., Sun, R., McCaw, Z. R., Yu, Z., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Brody, J. A., Cade, B. E., Carson, A. P., Carlson, J. C., Chami, N., Chen, Y-D. I. & 31 others, Curran, J. E., de Vries, P. S., Fornage, M., Franceschini, N., Freedman, B. I., Gu, C., Heard-Costa, N. L., He, J., Hou, L., Hung, Y., Irvin, M. R., Kaplan, R. C., Kardia, S. L. R., Kelly, T., Konigsberg, I., Kooperberg, C., Kral, B. G., Li, C., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Palmer, N. D., Peyser, P. A., Psaty, B. M., Raffield, L. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, bioRxiv, 71 p.

    Research output: Working paperPreprintResearch

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