Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training

    Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet

    Grau, K., Cauchi, S., Holst, C., Astrup, A., Martinez, J. A., Saris, W. H. M., Blaak, E. E., Oppert, J., Arner, P., Rössner, S., Macdonald, I. A., Klimcakova, E., Langin, D., Pedersen, Oluf Borbye, Froguel, P. & Sørensen, Thorkild I.A., 2010, In: American Journal of Clinical Nutrition. 91, 2, p. 472-479 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    ADAMTS1, MPDZ, MVD, and SEZ6: candidate genes for autosomal recessive nonsyndromic hearing impairment

    Bharadwaj, T., Schrauwen, I., Rehman, S., Liaqat, K., Acharya, A., Giese, A. P. J., Nouel-Saied, L. M., Nasir, A., Everard, J. L., Pollock, L. M., Zhu, S., Bamshad, M. J., Nickerson, D. A., Ali, R. H., Ullah, A., Wali, A., Ali, G., Santos-Cortez, R. L. P., Ahmed, Z. M., McDermott, B. M. & 4 others, Ansar, M., Riazuddin, S., Ahmad, W. & Leal, S. M., 2022, In: European Journal of Human Genetics. 30, p. 22-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner

    Saenz, C., Fang, Q., Gnanasekaran, Thiyagarajan, Trammell, Sam, Buijink, Jesse A., Pisano, P., Wierer, M., Moens, F., Lengger, B., Brejnrod, A. & Arumugam, Mani, 2023, In: Microbiology Spectrum. 11, 5, p. 1-18 e0393322.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    De-novo reconstruction and identification of transcriptional gene regulatory network modules differentiating single-cell clusters

    Oubounyt, M., Elkjaer, M. L., Laske, T., Grønning, Alexander GB, Moeller, M. J. & Baumbach, J., 2023, In: NAR Genomics and Bioinformatics. 5, 1, 17 p., lqad018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Escherichia coli CRISPR arrays from early life fecal samples preferentially target prophages

    Dion, M. B., Shah, S. A., Deng, Ling, Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Krogfelt, K. A., Schjørring, S., Horvath, P., Allard, A., Nielsen, Dennis Sandris, Petit, M. A. & Moineau, S., 2024, In: The ISME Journal. 18, 1, 9 p., wrae005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

    Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, Eriksson, J., Perola, M., Friedlander, Y., Gao, Y., Heppe, D. H. M., Holloway, J. W., Houston, D. K., Kanoni, S., Kim, Y., Laaksonen, M. A., Jääskeläinen, T., Lee, N. R., Lehtimäki, T., Lemaitre, R. N., Lu, W., Luben, R. N., Manichaikul, A., Männistö, S., Marques-Vidal, P., Monda, K. L., Ngwa, J. S., Perusse, L., van Rooij, F. J. A., Xiang, Y., Wen, W., Wojczynski, M. K., Zhu, J., Borecki, I. B., Bouchard, C., Cai, Q., Cooper, C., Dedoussis, G. V., Deloukas, P., Ferrucci, L., Forouhi, N. G., Hansen, Torben, Christiansen, L., Hofman, A., Johansson, I., Jørgensen, T., Karasawa, S., Khaw, K., Kim, M., Kristiansson, K., Li, H., Lin, X., Liu, Y., Lohman, K. K., Long, J., Mikkilä, V., Mozaffarian, D., North, K., Pedersen, Oluf Borbye, Raitakari, O., Rissanen, H., Tuomilehto, J., van der Schouw, Y. T., Uitterlinden, A. G., Carola Zillikens, M., Franco, O. H., Shyong Tai, E., Ou Shu, X., Siscovick, D. S., Toft, Ulla Marie Nørgaard, Monique Verschuren, W. M., Vollenweider, P., Wareham, N. J., Witteman, J. C. M., Zheng, W., Ridker, P. M., Kang, J. H., Liang, L., Jensen, M. K., Curhan, G. C., Pasquale, L. R., Hunter, D. J., Mohlke, K. L., Uusitupa, M., Adrienne Cupples, L., Rankinen, T., Orho-Melander, M., Wang, T., Chasman, D. I., Franks, P. W., Sørensen, Thorkild I.A., Hu, F. B., Loos, R. J. F., Nettleton, J. A. & Qi, L., 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

    Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    In Vitro Community Synergy between Bacterial Soil Isolates Can Be Facilitated by pH Stabilization of the Environment

    Herschend, J., Koren, K., Røder, Henriette Lyng, Brejnrod, A., Kühl, Michael & Burmølle, Mette, 2018, In: Applied and Environmental Microbiology. 84, 21, e01450.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    In vitro community synergy between bacterial soil isolates can be facilitated by pH stabilisation of the environment.

    Herschend, J., Koren, K., Røder, Henriette Lyng, Brejnrod, A. D., Kühl, Michael & Burmølle, Mette, 2018, In: Applied and Environmental Microbiology. 84, 21, p. 1-15 e01450-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    In vivo and ex vivo inflammatory markers of common metabolic phenotypes in humans

    Mærkedahl, R. B., Frøkiær, Hanne, Stenbæk, M. G., Nielsen, C. B., Lind, M. V., Lundtoft, C., Bohr, M. B., Ibrügger, S., Metzdorff, S. B., drb459, drb459, Pedersen, Oluf Borbye & Lauritzen, Lotte, 2018, In: Metabolic Syndrome and Related Disorders. 16, 1, p. 29-39 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo-controlled, double-blind, clinical trial

    Nilsson, A. G., Sundh, D., Backhed, F. & Lorentzon, M., 2018, In: Journal of Internal Medicine. 284, 3, p. 307-317

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes

    Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.

    Research output: Contribution to journal › Comment/debate › Research

  14. Published

    Mycobacterium tuberculosis Requires the Outer Membrane Lipid Phthiocerol Dimycocerosate for Starvation-Induced Antibiotic Tolerance

    Block, A. M., Namugenyi, S. B., Palani, Nagendra Prasad, Brokaw, A. M., Zhang, L., Beckman, K. B. & Tischler, A. D., 2023, In: mSystems. 8, 1, 19 p., e0069922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis

    Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

    Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, Treebak, Jonas Thue, 2021, In: Molecular Metabolism. 53, 101271.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

    Southey, M. C., Goldgar, D. E., Winqvist, R., Pylkäs, K., Couch, F., Tischkowitz, M., Foulkes, W. D., Dennis, J., Michailidou, K., van Rensburg, E. J., Heikkinen, T., Nevanlinna, H., Hopper, J. L., Dörk, T., Claes, K. B., Reis-Filho, J., Teo, Z. L., Radice, P., Catucci, I., Peterlongo, P. & 31 others, Tsimiklis, H., Odefrey, F. A., Dowty, J. G., Schmidt, M. K., Broeks, A., Hogervorst, F. B., Verhoef, S., Carpenter, J., Clarke, C., Scott, R. J., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Peto, J., Dos-Santos-Silva, I., Fletcher, O., Johnson, N., Bolla, M. K., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Marme, F., Bojesen, Stig Egil, Nordestgaard, Børge, Kjær, Susanne Krüger, Høgdall, Estrid Vilma Solyom, Høgdall, Claus Kim, Engelholm, S. A. & Australian Ovarian Cancer Study Group, A. O. C. S. G., Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 800-811

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

    Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., Moldovan, M., van Iperen, E., Hovingh, G. K., Demuth, I., Norman, K., Steinhagen-Thiessen, E., Demuth, J., Bertram, L., Liu, T., Coassin, S. & 31 others, Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., van der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René & LifeLines Cohort study group, L. C. S. G., Feb 2017, In: The Lancet Diabetes & Endocrinology. 5, 2, p. 97–105

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Papio spp. Colon microbiome and its link to obesity in pregnancy

    Li, Xuan Ji, Rensing, C., Taylor, W. L., Costelle, C., Brejnrod, A. D., Ferry, R. J. ,. J., Higgins, P. B., Folli, F., Kottapalli, K. R., Hubbard, G. B., Dick, E. J. ,. J., Yooseph, S., Nelson, K. E. & Schlabritz-Loutsevitch, N., Dec 2018, In: Journal of Medical Primatology. 47, 6, p. 393-401

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    RAD51B in Familial Breast Cancer

    Pelttari, L. M., Khan, S., Vuorela, M., Kiiski, J. I., Vilske, S., Nevanlinna, V., Ranta, S., Schleutker, J., Winqvist, R., Kallioniemi, A., Dörk, T., Bogdanova, N. V., Figueroa, J., Pharoah, P. D. P., Schmidt, M. K., Dunning, A. M., García-Closas, M., Bolla, M. K., Dennis, J., Michailidou, K. & 31 others, Wang, Q., Hopper, J. L., Southey, M. C., Rosenberg, E. H., Fasching, P. A., Beckmann, M. W., Peto, J., Dos-Santos-Silva, I., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Surowy, H., Guénel, P., Truong, T., Bojesen, Stig Egil, Nordestgaard, Børge, Benitez, J., González-Neira, A., Neuhausen, S. L., Anton-Culver, H., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Brüning, T., Lindblom, A., Margolin, S., Mannermaa, A., Hartikainen, J. M. & kConFab/AOCS Investigators, K. I., 2016, In: PLOS ONE. 11, 5, 18 p., e0153788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    1H MRS Assessment of Hepatic Fat Content. Comparison Between Normal- and Excess-weight Children and Adolescents

    Chabanova, E., Fonvig, Cilius Esmann, Bøjsøe, C., Holm, Jens-Christian & Thomsen, Henrik S., Aug 2017, In: Academic Radiology. 24, 8, p. 982-987 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents

    Fonvig, C. E., Chabanova, E., Andersson, E. A., Ohrt, J. D., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, 2015, In: PLOS ONE. 10, 8, 15 p., e0135018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites

    Rose, C. S., Ek, J., Urhammer, S. A., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Diabetes. 54, 10, p. 3026-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A 25-year-old woman with type 2 diabetes and liver disease

    Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study

    Lakka, T. A., Lintu, N., Väistö, J., Viitasalo, A., Sallinen, T., Haapala, E. A., Tompuri, T. T., Soininen, S., Karjalainen, P., Schnurr, T. M., Mikkonen, S., Atalay, M., Kilpeläinen, T. O., Laitinen, T., Laaksonen, D. E., Savonen, K., Brage, S., Schwab, U., Jääskeläinen, J., Lindi, V. & 1 others, Eloranta, A., 2020, In: Diabetologia. 63, p. 2270-2281

    Research output: Contribution to journal › Journal article › Research › peer-review

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