Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2022
  2. Published

    Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes

    Isidor, Marie Sophie, Dong, W., Servin-Uribe, R. I., Villarroel, J., Altıntaş, Ali, Ayala-Sumuano, J. T., Varela-Echavarría, A., Barrès, Romain, Stephanopoulos, G., Macotela, Y. & Emanuelli, Brice, 2022, In: International Journal of Obesity. 46, 3, p. 535-543

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

    Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Borg, M. L., Björnholm, M., Niu, Lili, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2022, In: Molecular and Cellular Proteomics. 21, 3, 19 p., 100207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD

    Schnurr, T. M., Katz, S. F., Justesen, Johanne Marie, O'Sullivan, J. W., Saliba-Gustafsson, P., Assimes, T. L., Carcamo-Orive, I., Ahmed, A., Ashley, E. A., Hansen, Torben & Knowles, J. W., 2022, In: Hepatology Communications. 6, 7, p. 1516-1526

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Isolation and Characterization of Human Brown Adipocytes

    Schéele, Camilla Charlotte Nielsen, Henriksen, T. I. & Nielsen, S., 2022, In: Methods in Molecular Biology. 2448, p. 217-234 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Jan Fahrenkrug (6/6 1947 – 10/11 2021)

    Rehfeld, Jens Frederik, Hannibal, Jens, Holst, Jens Juul, Hökfelt, T., de Muckadell, O. B. S. & Schwartz, Thue W., 2022, In: Peptides. 150, 170771.

    Research output: Contribution to journalEditorialResearch

  9. Published

    LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men

    Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Laboratory animal surgery, can we do better?

    Gantenbein, F., Nielsen, Thomas Svava, Hankenson, F. C., Cesarovic, N., Bollen, Peter & Bouard, D., 2022, In: Laboratory Animals. 56, Suppl. 1, p. 104-105 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  11. Published

    Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases

    Sveidahl Johansen, O., Ma, Tao & Gerhart-Hines, Zach, 2022, In: Molecular Metabolism. 60, 8 p., 101474.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

    Duncan, C. J. A., Skouboe, M. K., Howarth, S., Hollensen, A. K., Chen, R., Børresen, M. L., Thompson, B. J., Spegarova, J. S., Hatton, C. F., Stæger, F. F., Andersen, M. K., Whittaker, J., Paludan, S. R., Jørgensen, S. E., Thomsen, M. K., Mikkelsen, J. G., Heilmann, C., Buhas, D., Øbro, N. F., Bay, J. T. & 17 others, Marquart, Hanne Vibeke Hansen, Morena, M. T. D. L., Klejka, J. A., Hirschfeld, M., Borgwardt, L., Forss, I., Masmas, T., Poulsen, A., Noya, F., Rouleau, G., Hansen, Torben, Zhou, S., Albrechtsen, Anders, Alizadehfar, R., Allenspach, E. J., Hambleton, S. & Mogensen, T. H., 2022, In: Journal of Experimental Medicine. 219, 6, 26 p., e20212427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Lipolysis defect in people with obesity who undergo metabolic surgery

    Rydén, M., Andersson, D. P., Kotopouli, M. I., Stenberg, E., Näslund, E., Thorell, A., Sørensen, Thorkild I.A. & Arner, P., 2022, In: Journal of Internal Medicine. 294, 4, p. 667-678 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Lipolysis regulates major transcriptional programs in brown adipocytes

    Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Long-acting amylin analogues for the management of obesity

    Mathiesen, D. S., Bagger, J. I. & Knop, Filip Krag, 2022, In: Current Opinion in Endocrinology, Diabetes and Obesity. 29, 2, p. 183-190 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Long-term outcomes of dietary carbohydrate restriction for HbA1c reduction in type 2 diabetes mellitus are needed. Reply to Kang J and Ma E [letter]

    Thomsen, M. N., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, 6, p. 1060-1062 3 p.

    Research output: Contribution to journalComment/debateResearch

  17. Published

    Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk

    Leppanen, M. H., Haapala, E. A., Vaisto, J., Ekelund, U., Brage, S., Kilpeläinen, Tuomas O. & Lakka, T. A., 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 1, p. 255-266

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Longitudinal evaluation of an mHealth overweight and obesity management tool

    Langkjær, I. O. J., Fonvig, Cilius Esmann, Holm, L. A., Pihl, A. F. & Holm, Jens-Christian, 2022, In: mHealth. 8, 11 p., 2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Loss of Function Variants in the XPC Causes Severe Xeroderma Pigmentosum in Three Large Consanguineous Families

    Nawal, W., Ullah, A., Ullah, U., Farrakh, K., Ahmad, F., Khan, H., Ahmad, G. S., Khan, B., Ansar, M., Umm-e-Kalsoom & Ahmad, W., 2022, In: Klinische Padiatrie. 234, 3, p. 123-129 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts

    Andersen, M. K., Skotte, L., Jørsboe, E., Polito, R., Stæger, F. F., Aldiss, P., Hanghøj, K., Waples, R. K., Santander, C. G., Grarup, N., Dahl-Petersen, I. K., Diaz, L. J., Overvad, M., Senftleber, N. K., Søborg, B., Larsen, C. V. L., Lemoine, C., Pedersen, O., Feenstra, B., Bjerregaard, P. & 9 others, Melbye, M., Jørgensen, M. E., Færgeman, N. J., Koch, A., Moritz, Thomas, Gillum, M. P., Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2022, In: Gastroenterology. 162, 4, p. 1171-1182.e3

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    MAFA and MAFB regulate exocytosis-related genes in human β-cells

    Cataldo Bascunan, Luis Rodrigo, Singh, T., Achanta, K., Bsharat, S., Prasad, R. B., Luan, C., Renström, E., Eliasson, L. & Artner, I., 2022, In: Acta Physiologica. 234, 2, 14 p., e13761.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    MIntO: A Modular and Scalable Pipeline For Microbiome Metagenomic and Metatranscriptomic Data Integration

    Saenz, C., Nigro, E., Gunalan, V. & Arumugam, Mani, 2022, In: Frontiers in Bioinformatics. 2, 15 p., 846922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Macrophage activation marker sCD163 is associated with liver injury and hepatic insulin resistance in obese patients before and after Roux-en-Y gastric bypass

    Kazankov, K., Bojsen-Møller, K. N., Møller, H. J., Madsbad, Sten & Grønbæk, H., 2022, In: Physiological Reports. 10, 2, 11 p., e15157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Mapping the cord blood transcriptome of pregnancies affected by early maternal anemia to identify signatures of fetal programming

    Hatem, G., Hjort, Line, Asplund, O., Minja, D. T. R., Msemo, O. A., Møller, S. L., Lavstsen, Thomas, Grunnet, Louise Groth, Lusingu, J. P. A., Hansson, O., Christensen, Dirk Lund, Vaag, Allan, Artner, I., Theander, Thor Grundtvig, Groop, L., Schmiegelow, Christentze, Bygbjerg, Ib Christian & Prasad, R. B., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 5, p. 1303–1316 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Mechanism of glycogen synthase inactivation and interaction with glycogenin

    Marr, L., Biswas, Dipsikha, Daly, L. A., Browning, C., Vial, S. C. M., Maskell, D. P., Hudson, C., Bertrand, J. A., Pollard, J., Ranson, N. A., Khatter, H., Eyers, C. E., Sakamoto, Kei & Zeqiraj, E., 2022, In: Nature Communications. 13, 1, 14 p., 3372.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures

    Madsen, J. J., Ye, L., Frimurer, Thomas Michael & Olsen, O. H., 2022, In: Protein Science. 31, 11, 16 p., e4456.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: eLife. 11, 25 p., e70386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Mendelian randomization suggests a causal effect of abdominal obesity on postprandial lipemia

    Christiansen, Malene Revsbech, Hansen, Torben, Sørensen, Thorkild I.A., Grarup, Niels, García Ureña, Mario, Borisevich, D., Oppert, J., Martinez Hernandez, J. A., Blaak, E. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 184 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

    Nakao, T., Bick, A. G., Taub, M. A., Zekavat, S. M., Uddin, M. M., Niroula, A., Carty, C. L., Lane, J., Honigberg, M. C., Weinstock, J. S., Pampana, A., Gibson, C. J., Griffin, G. K., Clarke, S. L., Bhattacharya, R., Assimes, T. L., Emery, L. S., Stilp, A. M., Wong, Q., Broome, J. & 32 others, Laurie, C. A., Khan, A. T., Smith, A. V., Blackwell, T. W., Codd, V., Nelson, C. P., Yoneda, Z. T., Peralta, J. M., Bowden, D. W., Irvin, M. R., Boorgula, M., Zhao, W., Yanek, L. R., Wiggins, K. L., Hixson, J. E., Charles Gu, C., Peloso, G. M., Roden, D. M., Reupena, M. S., Hwu, C. M., DeMeo, D. L., North, K. E., Kelly, S., Musani, S. K., Bis, J. C., Lloyd-Jones, D. M., Johnsen, J. M., Preuss, M., Tracy, R. P., Loos, Ruth, The Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, T. S. O. L. A. G. A. S. (. G. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2022, In: Science Advances. 8, 14, eabl6579.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

    Maimets, Martti, Pedersen, M. T., Guiu, J., Dreier, J., Thodberg, Malte, Antoku, Yasuko, Schweiger, P. J., Rib, Leonor, Bardini Bressan, Raul, Miao, Y., Garcia, K. C., Sandelin, Albin Gustav, Serup, Palle & Jensen, Kim Bak, 2022, In: Nature Communications. 13, 12 p., 715.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

    Solomon, O., Huen, K., Yousefi, P., Küpers, L. K., González, J. R., Suderman, M., Reese, S. E., Page, C. M., Gruzieva, O., Rzehak, P., Gao, L., Bakulski, K. M., Novoloaca, A., Allard, C., Pappa, I., Llambrich, M., Vives, M., Jima, D. D., Kvist, T., Baccarelli, A. & 65 others, White, C., Rezwan, F. I., Sharp, G. C., Tindula, G., Bergström, A., Grote, V., Dou, J. F., Isaevska, E., Magnus, M. C., Corpeleijn, E., Perron, P., Jaddoe, V. W. V., Nohr, E. A., Maitre, L., Foraster, M., Hoyo, C., Håberg, S. E., Lahti, J., DeMeo, D. L., Zhang, H., Karmaus, W., Kull, I., Koletzko, B., Feinberg, J. I., Gagliardi, L., Bouchard, L., Ramlau-Hansen, C. H., Tiemeier, H., Santorelli, G., Maguire, R. L., Czamara, D., Litonjua, A. A., Langhendries, J. P., Plusquin, M., Lepeule, J., Binder, E. B., Verduci, E., Dwyer, T., Carracedo, Á., Ferre, N., Eskenazi, B., Kogevinas, M., Nawrot, T. S., Munthe-Kaas, M. C., Herceg, Z., Relton, C., Melén, E., Gruszfeld, D., Breton, C., Fallin, M. D., Ghantous, A., Nystad, W., Heude, B., Snieder, H., Hivert, M. F., Felix, J. F., Sørensen, Thorkild I.A., Bustamante, M., Murphy, S. K., Raikkönen, K., Oken, E., Holloway, J. W., Arshad, S. H., London, S. J. & Holland, N., 2022, In: Mutation Research - Reviews in Mutation Research. 789, 108415.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis

    Israelsen, M., Juel, H. B., Detlefsen, S., Madsen, B. S., Rasmussen, D. N., Larsen, T. R., Kjærgaard, M., Fernandes Jensen, M. J., Stender, S., Hansen, Torben, Krag, A., Thiele, M. & GALAXY and MicrobLiver consortiak, G. A. M. C., 2022, In: Clinical Gastroenterology and Hepatology. 20, 8, p. 1784-1794.e9 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Metabolic control of arginine and ornithine levels paces the progression of leaf senescence

    Liebsch, D., Juvany, M., Li, Z., Wang, H., Ziolkowska, A., Chrobok, D., Boussardon, C., Wen, X., Law, S. R., Janečková, H., Brouwer, B., Lindén, P., Delhomme, N., Stenlund, H., Moritz, Thomas, Gardeström, P., Guo, H. & Keech, O., 2022, In: Plant Physiology. 189, 4, p. 1943-1960

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Metabolite G-protein coupled receptor signaling: Potential regulation of eicosanoids

    Tang, X., Hou, Y., Schwartz, Thue W. & Haeggström, J. Z., 2022, In: Biochemical Pharmacology. 204, 7 p., 115208.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

    Talmor-Barkan, Y., Bar, N., Shaul, A. A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S. K., Fromentin, S., Dumas, M. E., Ehrlich, S. D., Pedersen, Oluf Borbye, Kornowski, R. & Segal, E., 2022, In: Nature Medicine. 28, 2, p. 295-302 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Metagenomic evidence for co-occurrence of antibiotic, biocide and metal resistance genes in pigs

    Li, Xuan Ji, Rensing, C., Vestergaard, G., Arumugam, Mani, Nesme, Joseph, Gupta, S., Brejnrod, A. D. & Sørensen, Søren Johannes, 2022, In: Environment International. 158, 10 p., 106899.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Methods in Bioarchaeology: What’s New in Profiling an Individual Inside and Out

    Freiwald, C., Belanich, Jonathan Robert & Rand, A., 2022, The Routledge Handbook of Mesoamerican Bioarchaeology. Tieslar, V. (ed.). Routledge, p. 577-600 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  40. Published

    MicroRNAs in non-alcoholic fatty liver disease: Progress and perspectives

    Hochreuter, Mette Yde, Dall, M., Treebak, Jonas Thue & Barrès, Romain, 2022, In: Molecular Metabolism. 65, 17 p., 101581.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Microbiome and metabolome features of the cardiometabolic disease spectrum

    Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. & 44 others, Coelho, L. P., Falony, G., Fellahi, S., Galan, P., Galleron, N., Helft, G., Hoyles, L., Isnard, R., Le Chatelier, E., Julienne, H., Olsson, L., Pedersen, H. K., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J. E., Schmidt, T. S. B., Vieira-Silva, S., Li, P., Zimmermann-Kogadeeva, M., Lewinter, C., Søndertoft, N. B., Hansen, T. H., Gauguier, D., Gøtze, J. P., Køber, Lars Valeur, Kornowski, R., drb459, drb459, Hansen, Torben, Zucker, J. D., Hercberg, S., Letunic, I., Bäckhed, F., Oppert, J. M., Nielsen, J., Raes, J., Bork, P., Stumvoll, M., Segal, E., Clément, K., Dumas, M. E., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2022, In: Nature Medicine. 28, 2, p. 303-314

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Microbiome-derived ethanol in nonalcoholic fatty liver disease

    Meijnikman, A. S., Davids, M., Herrema, H., Aydin, O., Tremaroli, V., Rios-Morales, M., Levels, H., Bruin, S., de Brauw, M., Verheij, J., Kemper, M., Holleboom, A. G., Tushuizen, M. E., Schwartz, T. W., Nielsen, J., Brandjes, D., Dirinck, E., Weyler, J., Verrijken, A., De Block, C. E. M. & 7 others, Vonghia, L., Francque, S., Beuers, U., Gerdes, V. E. A., Bäckhed, F., Groen, A. K. & Nieuwdorp, M., 2022, In: Nature Medicine. 28, p. 2100-2106

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Mild Cognitive Impairment Is Associated with Poorer Nutritional Status on Hospital Admission and after Discharge in Acutely Hospitalized Older Patients

    Bornæs, O., Andersen, A. L., Houlind, Morten Baltzer, Kallemose, T., Tavenier, J., Aharaz, A., Nielsen, Rikke Linnemann, Jørgensen, L. M., Beck, A. M., Andersen, Ove, Petersen, Janne & Pedersen, Mette Merete, 2022, In: Geriatrics (Switzerland). 7, 5, 16 p., 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Mixed-mode chromatography-mass spectrometry enables targeted and untargeted screening of carboxylic acids in biological samples

    Hodek, O., Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2022, In: Analytical Methods. 14, 10, p. 1015-1022 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native A beta oligomers to rats

    Baerends, E., Soud, K., Folke, J., Pedersen, A., Henmar, S., Konrad, Lisa, Lycas, M. D., Mori, Yuki, Pakkenberg, B., Woldbye, David Paul Drucker, Dmytriyeva, O. & Pankratova, Stanislava, 2022, In: Acta Neuropathologica Communications. 10, 1, 21 p., 113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Modulation of gut microbiota by Mantequilla and Melipona honeys decrease low-grade inflammation caused by high fructose corn syrup or sucrose in rats

    Coutiño-Hernández, D., Sánchez-Tapia, M., Leal-Vega, F., Bobadilla del Valle, M., Ledezma, H., Cervantes, R., Pedraza-Chaverri, J., Granados-Portillo, O., Díaz, D., Antunes-Ricardo, M., Gutiérrez-Uribe, J., Maya, Otoniel, Olin-Sandoval, V., Tovar, A. R. & Torres, N., 2022, In: Food Research International. 151, 13 p., 110856.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Molecular Insights into the Role of Pathogenic nsSNPs in GRIN2B Gene Provoking Neurodevelopmental Disorders

    Shah, A. A., Amjad, M., Hassan, J. U., Ullah, A., Mahmood, A., Deng, H., Ali, Y., Gul, F. & Xia, K., 2022, In: Genes. 13, 8, 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Monogenic diabetes variants in Emirati women with gestational diabetes are associated with risk of non-autoimmune diabetes within 5 years after pregnancy

    Daggag, H., Gjesing, A. P., Mohammad, A., Ängquist, Lars, Shobi, B., Antony, S., Haj, D., Al Tikriti, A., Buckley, A., Hansen, Torben & Barakat, M. T., 2022, In: Metabolism open. 16, 7 p., 100213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., Horikoshi, M., Mercader, J. M., Taliun, D., Moon, S., Kwak, S-H., Robertson, N. R., Rayner, N. W., Loh, M., Kim, B-J., Chiou, J. & 31 others, Miguel-Escalada, I., Della Briotta Parolo, P., Lin, K., Bragg, F., Preuss, M. H., Takeuchi, F., Nano, J., Guo, X., Lamri, A., Nakatochi, M., Scott, R. A., Lee, J., Huerta-Chagoya, A., Graff, M., Chai, J., Parra, E. J., Yao, J., Bielak, L. F., Grarup, Niels, Chen, W., Bork-Jensen, J., Islam, M. T., Jørgensen, M. E., Jørgensen, T., Linneberg, Allan René, Witte, D. R., Lind, L., Loos, Ruth, Hansen, Torben, Pedersen, Oluf Borbye & FinnGen, F., 2022, In: Nature Genetics. 54, 5, p. 560-572 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model

    Lorenzen, E., Contreras, V., Olsen, A. W., Andersen, P., Desjardins, D., Rosenkrands, I., Juel, H. B., Delache, B., Langlois, S., Delaugerre, C., Joubert, C., Dereuddre-Bosquet, N., Bébéar, C., De Barbeyrac, B., Touati, A., McKay, P. F., Shattock, R. J., Le Grand, R., Follmann, F. & Dietrich, J., 2022, In: Frontiers in Immunology. 13, 13 p., 1057375.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health

    Marabita, F., James, T., Karhu, A., Virtanen, H., Kettunen, K., Stenlund, H., Boulund, F., Hellström, C., Neiman, M., Mills, R., Perheentupa, T., Laivuori, H., Helkkula, P., Byrne, M., Jokinen, I., Honko, H., Kallonen, A., Ermes, M., Similä, H., Lindholm, M. & 9 others, Widén, E., Ripatti, S., Perälä-Heape, M., Engstrand, L., Nilsson, P., Moritz, Thomas, Miettinen, T., Sallinen, R. & Kallioniemi, O., 2022, In: Cell Systems. 13, 3, p. 241-255.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Multiomics signatures of type 1 diabetes with and without albuminuria

    Clos-Garcia, M., Ahluwalia, Tarun Veer Singh, Winther, S. A., Henriksen, P., Ali, M., Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, J. K., Hansen, Torben, Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2022, In: Frontiers in Endocrinology. 13, 17 p., 1015557.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

    Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    NAD+ and NAFLD - Caution, Causality, and Careful Optimism

    Dall, M., Hassing, Anna Skab & Treebak, Jonas Thue, 2022, In: The Journal of Physiology. 600, 5, p. 1135-1154

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site

    Sanders, M. J., Ratinaud, Y., Neopane, K., Bonhoure, N., Day, E. A., Ciclet, O., Lassueur, S., Pinta, M. N., Deak, M., Brinon, B., Christen, S., Steinberg, G. R., Barron, D. & Sakamoto, Kei, 2022, In: Journal of Biological Chemistry. 298, 5, 15 p., 101852.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents

    Lausten-Thomsen, U., Lund, Morten Asp Vonsild, Stinson, Sara, Frithioff-Bøjsøe, C., Holm, L. A., Baker, J. L., Fonvig, Cilius Esmann, Christiansen, M., Ängquist, Lars, Hansen, Torben & Holm, Jens-Christian, 2022, In: Journal of Pediatrics. 242, p. 74-78.e2 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

    Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Noninvasive proteomic biomarkers for alcohol-related liver disease

    Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz

    Keen, A. C., Pedersen, M. H., Lemel, L., Scott, D. J., Canals, M., Littler, D. R., Beddoe, T., Ono, Y., Shi, L., Inoue, A., Javitch, J. A. & Lane, J. R., 2022, In: Communications Biology . 5, 1, 10 p., 256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Off-label Prescription, Adverse Drug Events and Dosage of Psychotropic Drugs in Children and Adolescents with Obesity: A Retrospective Cohort Study

    Kamronn, T. M., Gade, Christina, Nielsen, S., Christensen, H. R., Dalhoff, Kim, Holm, Jens-Christian & Holst, H., 2022, In: Acta Scientific Pharmaceutical Sciences. 6, 6, p. 4-16 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published
  65. Published

    Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

    Nguyen-Tu, M., Harris, J., Martinez-Sanchez, A., Chabosseau, P., Hu, M., Georgiadou, E., Pollard, A., Otero, P., Lopez-Noriega, L., Leclerc, I., Sakamoto, Kei, Schmoll, D., Smith, D. M., Carling, D. & Rutter, G. A., 2022, In: Diabetologia. 65, p. 997-1011 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

    Lückmann, Michael, Iliyaz, Aslihan Shenol, Nissen, T. A. D., Petersen, Jacob Emil, Kouvchinov, David, Schwartz, Thue W. & Frimurer, Thomas Michael, 2022, In: ACS Medicinal Chemistry Letters. 13, 12, p. 1839-1847

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

    Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Outrunning obesity with Lac-Phe?

    Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  70. Published

    PEN2: Metformin’s new partner at lysosome

    Sakamoto, Kei & Jessen, N., 2022, In: Cell Research. 32, p. 507-508

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    PRDM16 stability and metabolically healthy adipose tissue

    Horvath, C. & Schéele, Camilla Charlotte Nielsen, 2022, In: Nature Metabolism. 4, p. 1095-1096

    Research output: Contribution to journalComment/debateResearch

  72. Published

    Palmitate impairs circadian transcriptomics in muscle cells through histone modification of enhancers

    Pillon, N. J., Puig, L. S., Altıntaş, Ali, Kamble, P. G., Casaní-Galdón, S., Gabriel, B. M., Barrès, Romain, Conesa, A., Chibalin, A. V., Näslund, E., Krook, A. & Zierath, Juleen R, 2022, In: Life Science Alliance. 6, 1, 14 p., e202201598.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Patients with psoriasis have a dysbiotic taxonomic and functional gut microbiota

    Todberg, T., Egeberg, Alexander, Zachariae, Claus, Sørensen, N., Pedersen, Oluf Borbye & Skov, Lone, 2022, In: British Journal of Dermatology. 187, 1, p. 89-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Peptides in the regulation of glucagon secretion

    Andersen, Daniel Bjørklund & Holst, Jens Juul, 2022, In: Peptides. 148, 19 p., 170683.

    Research output: Contribution to journalReviewResearchpeer-review

  75. Published

    Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps

    Hjort, Line, Novakovic, B., Cvitic, S., Saffery, R., Damm, Peter & Desoye, G., 2022, In: Epigenetics. 17, 13, p. 2188-2208 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    Plasma FGF21 concentrations are regulated by glucose independently of insulin and GLP-1 in lean, healthy humans

    Solomon, T. P. J., Carter, S., Haus, J. M., Karstoft, Kristian, Holstein-Rønsbo, Stephanie, Nielsen, M. S. & Gillum, M. P., 2022, In: PeerJ. 10, 16 p., e12755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, Freese, J., Herd, P., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., McCreight, J. C., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Pers, Tune H, Timshel, P., Ahluwalia, Tarun Veer Singh, Bønnelykke, Klaus, Bisgaard, H., Sørensen, Thorkild I.A., 23andMe Research Team, 2. R. T., Social Science Genetic Association Consortium, S. S. G. A. C. & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Possible prediction of obesity-related liver disease in children and adolescents using indices of body composition

    Johansen, M. J., Lund, Morten Asp Vonsild, Ängquist, Lars, Fonvig, Cilius Esmann, Holm, L. A., Chabanova, E., Thomsen, Henrik S., Hansen, Torben & Holm, Jens-Christian, 2022, In: Pediatric Obesity. 17, 10, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Post-translational modifications: The signals at the intersection of exercise, glucose uptake and insulin sensitivity

    Stocks, Ben Nicholas & Zierath, Juleen R, 2022, In: Endocrine Reviews. 43, 4, p. 654-677 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication

    Mikkelsen, Christina, Larsen, M. A. H., Sørensen, E., Hansen, Thomas Folkmann, Mikkelsen, S., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Kessing, Lars Vedel, Werge, Thomas, Ullum, H., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Thørner, L. W. & Didriksen, Maria, 2022, In: Psychiatry Research. 318, 7 p., 114944.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Prevalence of non-alcoholic fatty liver disease in patients with chronic kidney disease: a cross-sectional study

    Adrian, T., Sørensen, I. M. H., Knop, Filip Krag, Bro, S., Ballegaard, E. L. F., Nordestgaard, Børge, Fuchs, A., Kofoed, Klaus Fuglsang, Kühl, J. T., Sigvardsen, P. E., Hornum, Mads & Feldt-Rasmussen, Bo, 2022, In: Nephrology Dialysis Transplantation. 37, 10, p. 1927-1934 gfab266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Probiotics in hidradenitis suppurativa: a potential treatment option?

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.

    Research output: Contribution to journalComment/debateResearch

  83. Published

    Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

    Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Prolonged lipopolysaccharide-induced illness elevates glucagon-like peptide-1 and suppresses peptide YY: A human-randomized cross-over trial

    Brodersen, K., Mose, M., Ramer Mikkelsen, U., Jørgensen, J. O. L., Festersen Nielsen, M., Møller, N., Wegeberg, A., Brock, C., Hartmann, Bolette, Holst, Jens Juul & Rittig, N., 2022, In: Physiological Reports. 10, 18, 12 p., e15462.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism

    Haghikia, A., Zimmermann, F., Schumann, P., Jasina, A., Roessler, J., Schmidt, D., Heinze, P., Kaisler, J., Nageswaran, V., Aigner, A., Ceglarek, U., Cineus, R., Hegazy, A. N., Van Der Vorst, E. P. C., Doring, Y., Strauch, C. M., Nemet, I., Tremaroli, V., Dwibedi, C., Krankel, N. & 12 others, Leistner, D. M., Heimesaat, M. M., Bereswill, S., Rauch, G., Seeland, U., Soehnlein, O., Muller, D. N., Gold, R., Backhed, F., Hazen, S. L., Haghikia, A. & Landmesser, U., 2022, In: European Heart Journal. 43, 6, p. 518-533 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Protocol for qPCR analysis that corrects for cDNA amplification efficiency

    Damgaard, Mads Vargas & Treebak, Jonas Thue, 2022, In: STAR Protocols. 3, 3, 11 p., 101515.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

    Moreno Justicia, Roger, Gonzalez-Franquesa, A., Stocks, Ben Nicholas & Deshmukh, Atul Shahaji, 2022, In: STAR Protocols. 3, 1, 21 p., 101135.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes

    Damgaard, Mads Vargas, Jepsen, Sara Lind, Ashcroft, Stephen Paul, Holst, Jens Juul & Treebak, Jonas Thue, 2022, In: Nutrients. 14, 18, 11 p., 3741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Quantitative Phosphoproteomics of the Angiotensin AT2-Receptor Signaling Network Identifies HDAC1 (Histone-Deacetylase-1) and p53 as Mediators of Antiproliferation and Apoptosis

    Peluso, A. A., Kempf, S. J., Verano-braga, T., Rodrigues-ribeiro, L., Johansen, L. E., Hansen, M. R., Kitlen, G., Haugaard, A. H., Sumners, C., Ditzel, H. J., Santos, R. A., Bader, M., Larsen, M. R. & Steckelings, U. M., 2022, In: Hypertension. 79, 11, p. 2530-2541

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Rare coding variants in 35 genes associate with circulating lipid levels - A multi-ancestry analysis of 170,000 exomes

    Hindy, G., Dornbos, P., Chaffin, M. D., Liu, D. J., Wang, M., Selvaraj, M. S., Zhang, D., Park, J., Aguilar-Salinas, C. A., Antonacci-Fulton, L., Ardissino, D., Arnett, D. K., Aslibekyan, S., Atzmon, G., Ballantyne, C. M., Barajas-Olmos, F., Barzilai, N., Becker, L. C., Bielak, L. F., Bis, J. C. & 33 others, Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Bowden, D. W., Bown, M. J., Brody, J. A., Broome, J. G., Burtt, N. P., Cade, B. E., Centeno-Cruz, F., Chan, E., Chang, Y. C., Chen, Y. D. I., Cheng, C. Y., Choi, W. J., Chowdhury, R., Contreras-Cubas, C., Córdova, E. J., Correa, A., Cupples, L. A., Curran, J. E., Danesh, J., de Vries, P. S., Grarup, Niels, Hansen, Torben, Linneberg, Allan René, Loos, R. J. F., Pedersen, Oluf Borbye, Witte, D. R., AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, A. M. I. G. C., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C. & NHLBI TOPMed Lipids Working Group, N. T. L. W. G., 2022, In: American Journal of Human Genetics. 109, 1, p. 81-96 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes

    O'Connor, M. J., Schroeder, P., Huerta-Chagoya, A., Cortés-Sánchez, P., Bonàs-Guarch, S., Guindo Martínez, Marta, Cole, J. B., Kaur, V., Torrents, D., Veerapen, K., Grarup, Niels, Kurki, M., Friis, Carsten, Pedersen, Oluf Borbye, Brandslund, I., Linneberg, Allan René, Hansen, Torben, Leong, A., Florez, J. C. & Mercader, J. M., 2022, In: Diabetes. 71, 3, p. 554–565

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Recombinant human β-defensin 2 delivery improves smoking-induced lung neutrophilia and bacterial exacerbation

    Milad, N., Pineault, M., Bouffard, G., Maranda-Robitaille, M., Lechasseur, A., Beaulieu, M. J., Aubin, S., Jensen, Benjamin Anderschou Holbech & Morissette, M. C., 2022, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 323, 1, p. L37-L47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue

    Gonzalez-Franquesa, A., Gama-Perez, P., Kulis, M., Szczepanowska, K., Dahdah, N., Moreno-Gomez, S., Latorre-Pellicer, A., Fernández-Ruiz, R., Aguilar-Mogas, A., Hoffman, A., Monelli, E., Samino, S., Miró-Blanch, J., Oemer, G., Duran, X., Sanchez-Rebordelo, E., Schneeberger, M., Obach, M., Montane, J., Castellano, G. & 27 others, Chapaprieta, V., Sun, W., Navarro, L., Prieto, I., Castaño, C., Novials, A., Gomis, R., Monsalve, M., Claret, M., Graupera, M., Soria, G., Wolfrum, C., Vendrell, J., Fernández-Veledo, S., Enríquez, J. A., Carracedo, A., Perales, J. C., Nogueiras, R., Herrero, L., Trifunovic, A., Keller, M. A., Yanes, O., Sales-Pardo, M., Guimerà, R., Blüher, M., Martín-Subero, J. I. & Garcia-Roves, P. M., 2022, In: Redox Biology. 54, 18 p., 102353.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Reply - Letter to the editor - On carbohydrate restriction and health-related quality of life and cognition in type 2 diabetes

    Jensen, N. J., Thomsen, M. N., Skytte, M. J., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T. & Rungby, Jørgen, 2022, In: Clinical Nutrition. 41, 9, p. 2061-2062 2 p.

    Research output: Contribution to journalComment/debateResearch

  96. Published

    Reply to ‘Lactate as a major myokine and exerkine’

    Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C. H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, Watt, M. J., Xia, A., Zierath, Juleen R, Goodpaster, B. H. & Snyder, M., 2022, In: Nature Reviews Endocrinology. 18, 11, p. 713 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  97. Published

    Rhythmic history: Towards a new research agenda for the history of health and medicine

    Hussey, Kristin D., 2022, In: Endeavour. 46, 4, 10 p., 100846.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

    Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism

    Taskinen, M., Matikainen, N., Björnson, E., Söderlund, S., Ainola, M., Hakkarainen, A., Lundbom, N., Sihlbom, C., Thorsell, A., Andersson, L., Adiels, M., Hartmann, Bolette, Deacon, Carolyn F., Holst, Jens Juul, Packard, C. J. & Borén, J., 2022, In: European Journal of Endocrinology. 187, 1, p. 75-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: A randomised, double-blind, active-comparator, non-inferiority clinical trial

    Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Knudsen, E., Langholz, Ebbe, Dragsted, Lars Ove, Hansen, S. H., Krakauer, M., Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 10, p. 922-931 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Scale in the history of medicine

    Tybjerg, Karin, 2022, In: Studies in History and Philosophy of Science. 91, p. 221-233 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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