Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density

    Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jorgensen, N. R., Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Frontiers in Psychiatry. 9, 7 p., 781.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans

    Hansen, T. H., Madsen, M. T. B., Jørgensen, N. R., Cohen, A. S., Hansen, Torben, drb459, drb459, Pedersen, Oluf Borbye & Allin, K. H., 2018, In: European Journal of Clinical Nutrition. 72, p. 1046-1054 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Book Review: Exploring Emotion, Care, and Enthusiasm in “Unloved” Museum Collections. eds. Anna Woodham, Alison Hess, and Rhianedd Smith

    Hussey, Kristin D., 2021, In: Museums Worlds: Advances in Research. 9, p. 222-223 2 p.

    Research output: Contribution to journalLiterature reviewResearch

  5. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome

    Rasmussen, P., Nyberg, N., Jaroszewski, J. W., Krogh-Madsen, Rikke, Secher, Niels H. & Quistorff, B., 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 6, p. 1240-1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Breastfeeding and complementary feeding in relation to body mass index and overweight at ages 7 and 11 y: A path analysis within the Danish National Birth Cohort

    Morgen, C. S., Ängquist, Lars, Baker, J. L., Nybo Andersen, Anne-Marie, Sørensen, Thorkild I.A. & Michaelsen, Kim F., 2018, In: American Journal of Clinical Nutrition. 107, 3, p. 313-322 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Breastfeeding and later maternal risk of hypertension and cardiovascular disease - The role of overall and abdominal obesity

    Kirkegaard, H., Bliddal, M., Stovring, H., Rasmussen, K. M., Gunderson, E. P., Køber, Lars Valeur, Sørensen, Thorkild I.A. & Nohr, E. A., 2018, In: Preventive Medicine. 114, p. 140-148 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Breastfeeding duration in infancy and adult risks of type 2 diabetes in a high-income country

    Bjerregaard, L. G., Pedersen, D. C., Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Maternal and Child Nutrition. 15, 4, 9 p., e12869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism

    Schéele, Camilla Charlotte Nielsen & Wolfrum, C., 2020, In: Endocrine Reviews. 41, 1, p. 53-65

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk?

    Henningsen, J. B. & Schéele, Camilla Charlotte Nielsen, 2021, In: Annual Review of Physiology. 83, p. 279-301 23 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

    Sanchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Martinez Calejman, C., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Guertin, D. A., 9 Jan 2018, In: Cell Metabolism. 27, 1, p. 195-209.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Brown fat: the biological furnace that could burn away obesity

    Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.

    Research output: Contribution to journalJournal articleResearch

  14. Published

    Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers

    Loft, A., Forss, I., Siersbæk, M. S., Schmidt, S. F., Larsen, A. B., Madsen, J. G. S., Pisani, D. F., Nielsen, R., Aagaard, M. M., Mathison, A., Neville, M. J., Urrutia, R., Karpe, F., Amri, E. & Mandrup, S., 2015, In: Genes & Development. 29, p. 7-22 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest

    Andreasen, Laura Korsholm, Ghouse, J., Skov, M. W., Have, C. T., Ahlberg, G., Rasmussen, P. V., Linneberg, Allan René, Pedersen, Oluf Borbye, Platonov, P. G., Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2018, In: Frontiers in Physiology. 9, p. 1-9 894.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Building Bridges through Scientific Conferences

    Zierath, Juleen R, 17 Nov 2016, In: Cell. 167, 5, p. 1155-1158 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  17. Published

    Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial

    van Deuren, T., Smolders, L., Hartog, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Blaak, E. E. & Canfora, E. E., 2023, In: Frontiers in Nutrition. 9, 19 p., 1066950.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction

    Pedersen, Signe Schultz, Ingerslev, Lars Roed, Olsen, M., Prause, Michala Cecilie Burstein & Billestrup, Nils, 2024, In: FEBS Journal. 291, 3, p. 566-583

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

    Pichler, M. J., Yamada, C., Shuoker, B., Alvarez Silva, Maria Camila, Gotoh, A., Leth, M. L., Schoof, E., Katoh, T., Sakanaka, M., Katayama, T., Jin, C., Karlsson, N. G., Arumugam, Mani, Fushinobu, S. & Abou Hachem, M., 2020, In: Nature Communications. 11, 15 p., 3285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    C-cell hyperplasia accompanying thyroid diseases other than medullary carcinoma: an immunocytochemical study by means of antibodies to calcitonin and somatostatin

    Scopsi, L., di Palma, S., Ferrari, C., Holst, Jens Juul & Rehfeld, J. F., 1991, In: Modern Pathology. Vol 4, no.3, p. 297-304

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells

    Galuska, D., Pirkmajer, S., Barrès, Romain, Ekberg, K., Wahren, J. & Chibalin, A. V., 2011, In: P L o S One. 6, 12, p. e28294

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    C-reactive protein and cancer

    Allin, K. H., 2011, Faculty of Health Sciences, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  24. Published

    C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients

    Zimmermann, E., Anty, R., Tordjman, J., Verrijken, A., Gual, P., Tran, A., Iannelli, A., Gugenheim, J., Bedossa, P., Francque, S., Le Marchand-Brustel, Y., Clement, K., Van Gaal, L., Sørensen, Thorkild I.A. & Jess, T., 2011, In: Journal of Hepatology. 55, 3, p. 660-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    CAGEfightR: Cap Analysis of Gene Expression (CAGE) in R/Bioconductor

    Thodberg, Malte, Thieffry, A., Vitting-Seerup, K., Andersson, Robin & Sandelin, Albin Gustav, Apr 2018

    Research output: Other contributionResearch

  27. Published

    CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity

    Zizzari, P., He, R., Falk, S., Bellocchio, L., Allard, C., Clark, S., Lesté-Lasserre, T., Marsicano, G., Clemmensen, Christoffer, Perez-Tilve, D., Finan, B., Cota, D. & Quarta, C., 2021, In: Diabetes. 70, 2, p. 415-422 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published

    COVID-19 editorial: mechanistic links and therapeutic challenges for metabolic diseases one year into the COVID-19 pandemic

    Tessier, C. M., Kokkinos, A., Mingrone, G., Koliaki, C., Zierath, Juleen R & Mantzoros, C. S., 2021, In: Metabolism. 119, 154769.

    Research output: Contribution to journalEditorialResearch

  30. Published

    CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice

    Wang, C., Lundh, M., Fu, A., Kriszt, R., Huang, T. L., Lynes, M. D., Leiria, L. O., Shamsi, F., Darcy, J., Greenwood, B. P., Narain, N. R., Tolstikov, V., Smith, K. L., Emanuelli, Brice, Chang, Y., Hagen, S., Danial, N. N., Kiebish, M. A. & Tseng, Y., 2020, In: Science Translational Medicine. 12, 558, 15 p., eaaz8664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    CRTH2 receptor ligands for therapeutic use

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/115382 A1

    Research output: Patent

  32. Published

    CRTH2 receptor ligands for therapeutic use - B-series

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E. & Högberg, T., 2005, Patent No. WO 2005/115374 A1

    Research output: Patent

  33. Published

    CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

    Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Calcitonin gene-related peptide: effect on contractile activity and luminal-cross-sectional area in isolated, perfused porcine ileum

    Rasmussen, T. N., Gregersen, H., Harling, H. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 27, p. 787-792

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Calcium sensing in exocytosis

    Gustavsson, N., Wu, B. & Han, W., 2012, In: Advances in Experimental Medicine and Biology. 740, p. 731-57 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion

    Gustavsson, N. & Han, W., Aug 2009, In: Bioscience Reports. 29, 4, p. 245-59 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue

    Pardo, R., Vila, M., Cervela, L., de Marco, M., Gama-Perez, P., Gonzalez-Franquesa, A., Statuto, L., Vilallonga, R., Simo, R., Garcia-Roves, P. M. & Villena, J. A., 2019, In: FASEB Journal. 33, 2, p. 2343-2358

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat

    Plucinska, Kaja, Jespersen, N. Z., Brown, E. L., Petersen, P. S., Rupar, K., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Emanuelli, Brice, 2020, In: Frontiers in Endocrinology. 11, 7 p., 579785.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?

    Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Can breastfeeding promote an antibiotic-resilient microbiome?

    Stokholm, Jakob & Thorsen, Jonathan Jan Ilve, 2023, In: Med. 4, 2, p. 67-68 2 p.

    Research output: Contribution to journalComment/debateResearch

  42. Published

    Can we target obesity using a single-cell atlas of adipose tissue?

    Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2022, In: Med. 3, 5, p. 276-278 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. E-pub ahead of print

    Canagliflozin or acarbose versus placebo to ameliorate post-bariatric hypoglycaemia - The HypoBar I randomized clinical trial protocol

    Lobato, C. B., wql596, wql596, Bojsen-Møller, Kirstine Nyvold, Martinussen, C., Veedfald, Simon, Holst, Jens Juul, Madsbad, Sten, Jørgensen, N. B. & Dirksen, Carsten Moro, 2024, (E-pub ahead of print) In: Diabetic Medicine. e15320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Cancer and Pain

    Hansen, R. B. & Falk, S., Nov 2018, The Oxford Handbook of the Neurobiology of Pain. Oxford University Press

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  45. Published

    Cancer risk by combined levels of YKL-40 and C-reactive protein in the general population

    Allin, K. H., Bojesen, Stig Egil, Johansen, Julia Sidenius & Nordestgaard, Børge, 3 Jan 2012, In: B J C. 106, 1, p. 199-205 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

    Wei, T-T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, J. M., Chen, I. Y., Wo, H-T., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J-J., Yeh, C-F., Yang, K-C. & 5 others, Lau, E., Lynch, K. L., Rivas, M., Kobilka, B. K. & Wu, J. C., 2022, In: Cell. 185, 10, p. 1676-1693.e23

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Capturing Epidemics: Photographs by Howalt

    Tybjerg, Karin, Scott-Fordsmand, Helene & Howalt, N., 2020

    Research output: Non-textual form2D/3D (psysical products)Research

  48. Published

    Carbon source availability drives nutrient utilization in CD8+ T cells

    Kaymak, I., Luda, Katarzyna Maria, Duimstra, L. R., Ma, E. H., Longo, J., Dahabieh, M. S., Faubert, B., Oswald, B. M., Watson, M. J., Kitchen-Goosen, S. M., DeCamp, L. M., Compton, S. E., Fu, Z., DeBerardinis, R. J., Williams, K. S., Sheldon, R. D. & Jones, R. G., 2022, In: Cell Metabolism. 34, 9, p. 1298-1311 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine

    Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

    Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, Allan René, Pedersen, Oluf Borbye, Kiebish, M. A., Qvortrup, Klaus, Han, X., Pedersen, Bente Klarlund, Jastroch, M., Mandrup, S., Kjær, Andreas, Gygi, S. P., Hansen, Torben, Gillum, M. P., Grarup, Niels, Emanuelli, Brice, Nielsen, S., Schéele, Camilla Charlotte Nielsen, Tseng, Y., Færgeman, N. J. & Gerhart-Hines, Zach, 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Cardiorespiratory Fitness and Adiposity as Determinants of Metabolic Health-Pooled Analysis of Two Twin Cohorts

    Jukarainen, S., Holst, R., Dalgård, C., Piirilä, P., Lundbom, J., Hakkarainen, A., Lundbom, N., Rissanen, A., Kaprio, J., Kyvik, K. O., Sørensen, Thorkild I.A. & Pietiläinen, K. H., 1 May 2017, In: The Journal of clinical endocrinology and metabolism. 102, 5, p. 1520-1528 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Cardiovascular Risk Profile Among Patients With Inflammatory Bowel Disease: A Population-based Study of More Than 100 000 Individuals

    Aarestrup, J., Jess, T., Kobylecki, C. J., Nordestgaard, Børge & Allin, K. H., 2019, In: Journal of Crohn's and Colitis. 13, 3, p. 319-323 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

    Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, Dec 2017, In: Diabetes Care. 40, 12, p. 1771-1778 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Cardiovascular biomarkers in clinical studies of type 2 diabetes

    Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1350-1360

    Research output: Contribution to journalReviewResearchpeer-review

  55. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  56. Published

    Cardiovascular effects of incretins - focus on glucagon-like peptide-1 receptor agonists

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Cardiovascular Research. p. 886–904 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  57. Published

    Cardiovascular safety and benefits of GLP-1 receptor agonists

    Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

    Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

    Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challenges

    Yuan, S., Merino, Jordi & Larsson, S. C., 2023, In: Diabetologia. 66, p. 800-812 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  61. Published

    Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

    Eriksson, J., Haring, R., Grarup, Niels, Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, Torben, Mellström, D., Pedersen, Oluf Borbye, Nauck, M., Lorentzon, M., Nystrup Husemoen, L. L., Völzke, H., Karlsson, M., Baumeister, S. E., Linneberg, Allan René & Ohlsson, C., 2017, In: PloS one. 12, 4, 15 p., e0176277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Causality between physical activity, sedentary behavior and obesity: A Mendelian randomization study

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 536-536 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  63. Published

    Cause-Specific Mortality According to Urine Albumin Creatinine Ratio in the General Population

    Skaaby, T., Husemoen, L. L. N., Ahluwalia, Tarun Veer Singh, Rossing, Peter, Jørgensen, T., Thuesen, B. H., Pisinger, C., Rasmussen, K. & Linneberg, Allan René, 2014, In: PLOS ONE. 9, 3, p. 1-10 10 p., e93212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Causes of Outcome Learning: a causal inference-inspired machine learning approach to disentangling common combinations of potential causes of a health outcome

    Rieckmann, Andreas, Dworzynski, P., Arras, L., Lapuschkin, S., Samek, W., Arah, O. A., Rod, Naja Hulvej & Ekstrøm, Claus Thorn, 2022, In: International Journal of Epidemiology. 51, 5, p. 1622–1636 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle

    Abdelmoez, A. M., Dmytriyeva, O., Zurke, Y. X., Trauelsen, Mette, Marica, A. A., Savikj, M., Smith, J. A. B., Monaco, C., Schwartz, Thue W., Krook, A. & Pillon, N. J., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 324, 4, p. E289-E298 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Cell specificity of the cytoplasmic Ca2+ response to tolbutamide is impaired in beta-cells from hyperglycemic mice

    Gustavsson, N., Larsson-Nyrén, G. & Lindström, P., Aug 2006, In: The Journal of endocrinology. 190, 2, p. 461-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis

    Spindler, K. G., Boysen, A. K., Pallisgård, N., Johansen, Julia Sidenius, Tabernero, J., Sørensen, M. M., Jensen, B. V., Hansen, Torben, Sefrioui, D., Andersen, R. F., Brandslund, I. & Jakobsen, A., Sep 2017, In: Oncologist. 22, 9, p. 1049-1055 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  68. Published

    Cell-free DNA and RNA - measurement and applications in clinical diagnostics with focus on metabolic disorders

    Drag, Markus Hodal & Kilpeläinen, Tuomas O., 2021, In: Physiological Genomics. 53, 1, p. 33-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Center for epidemiologisk grundforskning.

    Olsen, J., Melbye, M., Sørensen, Thorkild I.A. & Aaby, P., 26 Feb 2001, In: Ugeskrift for Laeger. 163, 9, p. 1296-1297 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals

    Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, Jens Juul, Baaré, W. F. C., Højgaard, Liselotte, Almdal, T. & Knudsen, G. M., 8 Apr 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-5889 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis

    McGlashon, J. M., Gorecki, M. C., Kozlowski, A. E., Thirnbeck, C. K., Markan, K. R., Leslie, K. L., Kotas, M. E., Potthoff, M. J., Richerson, G. B. & Gillum, M. P., May 2015, In: Cell Metabolism. 21, 5, p. 692-705 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

    Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study

    van Duinkerken, E., Bernardes, G., van Bloemendaal, L., Veltman, D. J., Barkhof, F., Mograbi, D. C., Gerdes, V. E. A., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M., ten Kulve, J. & Ijzerman, R. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 415-424 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Cerebral small vessel disease genomics and its implications across the lifespan

    Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, Saba, Y., Satizabal, C. L., Beaudet, G., Petit, L., Tsuchida, A., Zago, L., Schilling, S., Sigurdsson, S., Gottesman, R. F., Lewis, C. E., Aggarwal, N. T., Lopez, O. L., Smith, J. A., Valdés Hernández, M. C., van der Grond, J., Wright, M. J., Knol, M. J., Dörr, M., Thomson, R. J., Bordes, C., Le Grand, Q., Duperron, M. G., Smith, A. V., Niessen, W. J., Pers, Tune H, Ingason, A., Francke Christensen, A., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, International Network against Thrombosis (INVENT) Consortium, I. N. A. T. (. C. & International Headache Genomics Consortium (IHGC), I. H. G. C. (., 2020, In: Nature Communications. 11, 1, 18 p., 6285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Cerebrovascular changes following administration of gammaglobulins against substance P or calcitonin gene related peptide in monkey with subarachnoid haemorrhage

    Shiokawa, Y., Holst, Jens Juul, Rasmussen, J. T. N., Schmidt, P. & Svendgaard, N., 1993, In: British J. of Neurosurgery. 7, p. 507-518

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Challenges in tackling energy expenditure as obesity therapy: From preclinical models to clinical application

    Löffler, M. C., Betz, M. J., Blondin, D. P., Augustin, R., Sharma, A. K., Tseng, Y. H., Schéele, Camilla Charlotte Nielsen, Zimdahl, H., Mark, M., Hennige, A. M., Wolfrum, C., Langhans, W., Hamilton, B. S. & Neubauer, H., 2021, In: Molecular Metabolism. 51, 15 p., 101237.

    Research output: Contribution to journalReviewResearchpeer-review

  77. Published

    Change in Overweight from Childhood to Early Adulthood and Risk of Type 2 Diabetes

    Bjerregaard, L. G., Jensen, B. W., Ängquist, Lars, Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 2018, In: The New England Journal of Medicine. 378, 14, p. 1302-1312 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection

    Kays Mohammed Ali, Y., Dolin, T. G., Damm Nybing, J., Lykke, J., Hvid Linden, F., Høgh-Schmidt, E., Sørensen, Thorkild I.A., Christensen, J. F., Nielsen, Yousef Jesper Wirenfeldt, Stenfatt Larsen, J., Madsbad, Sten, Johansen, Julia Sidenius, Svane, M. S. & Lang Lehrskov, L., 2024, In: International Journal of Obesity. 48, 4, p. 533-541 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Change in body mass index from childhood onwards and risk of adult cardiovascular disease

    Bjerregaard, L. G., Adelborg, K. & Baker, J. L., 2020, In: Trends in Cardiovascular Medicine. 30, 1, p. 39-45 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors

    Stocks, T., Taylor, M. A., Ängquist, Lars, Macdonald, I. A., Arner, P., Holst, C., Oppert, J., Martinez, J. A., Rössner, S., Polak, J., Langin, D., Saris, W. H. M., Astrup, A. & Sørensen, Thorkild I.A., 2013, In: Obesity Facts. 6, 3, p. 217-227 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Change in weight status from childhood to early adulthood and late adulthood risk of colon cancer in men: a population-based cohort study

    Jensen, B. W., Bjerregaard, L. G., Ängquist, Lars, Gögenur, Ismail, Renehan, A. G., Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 1 Oct 2018, In: International Journal of Obesity. 42, p. 1797-1803 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Changes and correlations in height from 7 to 69 years of age across the birth years of 1930 to 1989

    Pedersen, D. C., Meyle, K. D., Ängquist, Lars, Andersen, Ingelise, Tjønneland, Anne, Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Aarestrup, J. & Baker, J. L., 2020, In: American Journal of Human Biology. 32, 4, e23378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Changes in BMI and physical activity from youth to adulthood distinguish normal-weight, metabolically obese adults from those who remain healthy

    Viitasalo, A., Pahkala, K., Lehtimäki, T., Viikari, J. S. A., Tammelin, T. H., Raitakari, O. & Kilpeläinen, Tuomas O., 2022, In: Frontiers in Endocrinology. 13, 7 p., 923327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Changes in Childhood Body-Mass Index and Risk of Venous Thromboembolism in Adulthood

    Sundbøll, J., Ängquist, Lars, Adelborg, K., Gjærde, L. K., Ording, A., Sørensen, Thorkild I.A., Baker, J. L. & Sørensen, H. T., 2019, In: Journal of the American Heart Association. 8, 6, 20 p., e011407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects

    Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, Dorte, Almdal, Thomas Peter, Naver, L. S., Hvolris, L. E., Rehfeld, Jens Frederik, Wulff, B. S., Clausen, T. R., Hansen, D. L., Holst, Jens Juul & Madsbad, Sten, 2012, In: Obesity Surgery. 22, 7, p. 1084-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides

    Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Changes in Vitamin D Status in Overweight Middle-Aged Adults with or without Impaired Glucose Metabolism in Two Consecutive Nordic Summers

    Lundstrom, P., Caidahl, K., Eriksson, M. J., Fritz, T., Krook, A., Zierath, Juleen R & Rickenlund, A., 2019, In: Journal of Nutrition and Metabolism. 2019, p. 1-8 1840374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Changes in adult obesity prevalence in Denmark, 1987-2021: age-period-cohort analysis of nationally representative data

    Schramm, S., Sørensen, Thorkild I.A., Davidsen, M. & Tolstrup, J. S., 2023, In: European Journal of Public Health. 33, 3, p. 463–467 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Changes in intake of dairy product subgroups and risk of type 2 diabetes: modelling specified food substitutions in the Danish Diet, Cancer and Health cohort

    Ibsen, D. B., Overvad, K., Laursen, A. S. D., Halkjær, J., Tjønneland, Anne, Kilpeläinen, Tuomas O., Parner, E. T. & Jakobsen, M. U., 2021, In: European Journal of Nutrition. 60, p. 3449–3459 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Changes in lipid and carotenoid metabolism in Chlamydomonas reinhardtii during induction of CO2-concentrating mechanism: Cellular response to low CO2 stress

    Abreu, I. N., Aksmann, A., Bajhaiya, A. K., Benlloch, R., Giordano, M., Pokora, W., Selstam, E. & Moritz, Thomas, 2020, In: Algal Research. 52, 12 p., 102099.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Changes in oxidative nucleic acid modifications and inflammation following one-week treatment with the bile acid sequestrant sevelamer: Two randomised, placebo-controlled trials

    Brønden, A., Larsen, E. L., Karstoft, K., Henriksen, T., Vilsbøll, Tina, Poulsen, Henrik Enghusen & Knop, Filip Krag, Feb 2020, In: Journal of Diabetes and its Complications. 34, 2, 8 p., 107446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births

    Philips, E. M., Santos, S., Trasande, L., Aurrekoetxea, J. J., Barros, H., von Berg, A., Bergström, A., Bird, P. K., Brescianini, S., Chaoimh, C. N., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Costet, N., Criswell, R., Crozier, S., Eggesbo, M., Fantini, M. P., Farchi, S. & 48 others, Forastiere, F., van Gelder, M. M. H. J., Georgiu, V., Godfrey, K. M., Gori, D., Hanke, W., Heude, B., Hryhorczuk, D., Iñiguez, C., Inskip, H., Karvonen, A. M., Kenny, L. C., Kull, I., Lawlor, D. A., Lehmann, I., Magnus, P., Manios, Y., Melén, E., Mommers, M., Morgen, C. S., Moschonis, G., Murray, D., Nohr, E. A., Nybo Andersen, Anne-Marie, Oken, E., Oostvogels, A. J. J. M., Papadopoulou, E., Pekkanen, J., Pizzi, C., Polanska, K., Porta, D., Richiardi, L., Rifas-Shiman, S. L., Roeleveld, N., Rusconi, F., Santos, A. C., Sørensen, Thorkild I.A., Standl, M., Stoltenberg, C., Sunyer, J., Thiering, E., Thijs, C., Torrent, M., Vrijkotte, T. G. M., Wright, J., Zvinchuk, O., Gaillard, R. & Jaddoe, V. W. V., 2020, In: PLoS Medicine. 17, 8, 25 p., e1003182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Changes in serum zonulin in individuals with morbid obesity after weight-loss interventions: a prospective cohort study

    Aasbrenn, M., Lydersen, S. & Farup, P. G., 2020, In: BMC Endocrine Disorders. 20, 1, 9 p., 108.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Changes in the Homeostatic Appetite System After Weight Loss Reflect a Normalization Toward a Lower Body Weight

    DeBenedictis, J. N., Nymo, S., Ollestad, K. H., Boyesen, G. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Truby, H., Kulseng, B. & Martins, C., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 7, p. e2538-e2546 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Changes in waist circumference and mortality in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Overvad, K. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Changes in waist circumference and the incidence of acute myocardial infarction in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Stegger, J. G., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 10, p. e26849

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Changes in waist circumference and the incidence of diabetes in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 8, p. e23104

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Changes in weight status during the COVID-19 pandemic: impact of educational level and mental health

    Rosenkilde, S., Sørensen, Thorkild I.A., Algren, M. H. & Thygesen, L. C., 2024, In: European Journal of Public Health. 34, 1, p. 190–195 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Changing genetic architecture of body mass index from infancy to early adulthood: an individual based pooled analysis of 25 twin cohorts

    Silventoinen, K., Li, W., Jelenkovic, A., Sund, R., Yokoyama, Y., Aaltonen, S., Piirtola, M., Sugawara, M., Tanaka, M., Matsumoto, S., Baker, L. A., Tuvblad, C., Tynelius, P., Rasmussen, F., Craig, J. M., Saffery, R., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Martin, N. G. & 37 others, Medland, S. E., Montgomery, G. W., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Christensen, K., Skytthe, A., Kyvik, K. O., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Corley, R. P., Huibregtse, B. M., Knafo-Noam, A., Mankuta, D., Abramson, L., Haworth, C. M. A., Plomin, R., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Duncan, G. E., Buchwald, D., Burt, S. A., Klump, K. L., Llewellyn, C. H., Fisher, A., Boomsma, D., Sørensen, Thorkild I.A. & Kaprio, J., 2022, In: International Journal of Obesity. 46, p. 1901–1909 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Chap.10. Degradation of glucagons

    Holst, Jens Juul, 1991, Degradation of Bioactive Substances: Physiology and Pathophysiology. Boca Raton, Florida: CRC Press, p. 167-180

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

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