Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    A Prospective Cohort Study in Patients with Type 2 Diabetes Mellitus for Validation of Biomarkers (PROVALID) - Study Design and Baseline Characteristics

    Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, Peter, Heerspink, H. L. & Mayer, G., 2018, In: Kidney and Blood Pressure Research. 43, 1, p. 181-190

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A Prospective Study of Height and Body Mass Index in Childhood, Birth Weight, and Risk of Adult Glioma Over 40 Years of Follow-up

    Kitahara, C. M., Gamborg, Michael Orland, Rajaraman, P., Sørensen, Thorkild I.A. & Baker, J. L., 2014, In: American Journal of Epidemiology. 180, 8, p. 821-829 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A Somewhat Subjective Introduction to Gene Mapping through Nonparametric Linkage Analysis

    Ängquist, Lars, 2008, Genetic Recombination Research Progress. Schultz, J. H. (ed.). Nova Biomedical Books, 60 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  4. Published

    A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease

    Gretarsdottir, S., Helgason, H., Helgadottir, A., Sigurdsson, A., Thorleifsson, G., Magnusdottir, A., Oddsson, A., Steinthorsdottir, V., Rafnar, T., de Graaf, J., Daneshpour, M. S., Hedayati, M., Azizi, F., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Eyjolfsson, G., Sigurdardottir, O., Olafsson, I. & 8 others, Kiemeney, L. A., Pedersen, Oluf Borbye, Sulem, P., Thorgeirsson, G., Gudbjartsson, D. F., Holm, H., Thorsteinsdottir, U. & Stefansson, K., Sep 2015, In: P L o S Genetics. 11, 9, 20 p., e1005379.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells

    Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  6. Published

    A Unified Discussion on the Concept of Score Functions Used in the Context of Nonparametric Linkage Analysis

    Ängquist, Lars, 2008, In: Bioinformatics and Biology Insights. 2, p. 119-132 PMID:19812770.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

    Staiger, H., Stancáková, A., Zilinskaite, J., Vänttinen, M., Hansen, T., Marini, M. A., Hammarstedt, A., Jansson, P., Sesti, G., Smith, U., Pedersen, Oluf Borbye, Laakso, M., Stefan, N., Fritsche, A. & Häring, H., 2008, In: Diabetes. 57, 2, p. 514-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients

    Samkani, A., fbg982, fbg982, Kandel, D., Kjaer, S., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In: British Journal of Nutrition. 119, 8, p. 910-917 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial

    fbg982, fbg982, Samkani, A., Petersen, A. D., Thomsen, M. N., Astrup, A., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Larsen, T. M., Haugaard, Steen Bendix & Krarup, T., 2019, In: Diabetologia. 62, 11, p. 2066-2078 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A catalog of the mouse gut metagenome: [incl. Author Correction]

    Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, Sung, J. J. Y., Liang, Q., Li, J., Jia, H., Lan, Z., Tremaroli, V., Dworzynski, P., Nielsen, H. B., Bäckhed, G. F., Dore, J., Le Chatelier, E., Ehrlich, S. D., Lin, J. C., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A century of trends in adult human height

    Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 26 Jul 2016, In: eLife. 5, 29 p., e13410.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning

    Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism

    Feng, D., Liu, T., Sun, Z., Bugge, A. S., Mullican, S. E., Alenghat, T., Liu, X. S. & Lazar, M. A., 11 Mar 2011, In: Science (New York, N.Y.). 331, 6022, p. 1315-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetes.

    Hornbak, M., Allin, K. H., Jensen, M. L., Lau, C. J., Witte, D. R., Jørgensen, M. E., Sandbæk, A., Lauritzen, T., Andersson, Åsa, Pedersen, Oluf Borbye & Hansen, Torben, 2014, In: PloS One. 9, 8, 10 p., e104837.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

    Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, Nielsen, R., Albrechtsen, Anders & Hansen, Torben, 2014, In: Nature. 512, 7513, p. 190-193 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  16. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

    Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects

    Nielsen, E. D., Hansen, L., Lajer, M., Andersen, K. L., Echwald, S. M., Urhammer, S. A., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Clinical Biochemistry. 37, 8, p. 660-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A community resource for paired genomic and metabolomic data mining

    Schorn, M. A., Verhoeven, S., Ridder, L., Huber, F., Acharya, D. D., Aksenov, A. A., Aleti, G., Moghaddam, J. A., Aron, A. T., Aziz, S., Bauermeister, A., Bauman, K. D., Baunach, M., Beemelmanns, C., Beman, J. M., Berlanga-Clavero, M. V., Blacutt, A. A., Bode, H. B., Boullie, A., Brejnrod, A. & 90 others, Bugni, T. S., Calteau, A., Cao, L., Carrión, V. J., Castelo-Branco, R., Chanana, S., Chase, A. B., Chevrette, M. G., Costa-Lotufo, L. V., Crawford, J. M., Currie, C. R., Cuypers, B., Dang, T., de Rond, T., Demko, A. M., Dittmann, E., Du, C., Drozd, C., Dujardin, J., Dutton, R. J., Edlund, A., Fewer, D. P., Garg, N., Gauglitz, J. M., Gentry, E. C., Gerwick, L., Glukhov, E., Gross, H., Gugger, M., Matus, D. G. G., Helfrich, E. J. N., Hempel, B., Hur, J., Iorio, M., Jensen, P. R., Kang, K. B., Kaysser, L., Kelleher, N. L., Kim, C. S., Kim, K. H., Koester, I., König, G. M., Leao, T., Lee, S. R., Lee, Y., Li, Xuan Ji, Little, J. C., Maloney, K. N., Männle, D., Martin H., C., McAvoy, A. C., Metcalf, W. W., Mohimani, H., Molina-Santiago, C., Moore, B. S., Mullowney, M. W., Muskat, M., Nothias, L., O'Neill, E. C., Parkinson, E. I., Petras, D., Piel, J., Pierce, E. C., Pires, K., Reher, R., Romero, D., Roper, M. C., Rust, M., Saad, H., Saenz, C., Sanchez, L. M., Sørensen, Søren Johannes, Sosio, M., Süssmuth, R. D., Sweeney, D., Tahlan, K., Thomson, R. J., Tobias, N. J., Trindade-Silva, A. E., van Wezel, G. P., Wang, M., Weldon, K. C., Zhang, F., Ziemert, N., Duncan, K. R., Crüsemann, M., Rogers, S., Dorrestein, P. C., Medema, M. H. & van der Hooft, J. J. J., 2021, In: Nature Chemical Biology. 17, 4, p. 363-368

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A community-based transcriptomics classification and nomenclature of neocortical cell types

    Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V., Bergmann, T. B., Bystron, I., Capogna, M., Chang, Y., Clemens, A., De Kock, C. P. J., Defelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D., Fiáth, R. & 53 others, Fishell, G. J., Foggetti, A., Gao, X., Ghaderi, P., Goriounova, N. A., Güntürkün, O., Hagihara, K., Hall, Vanessa Jane, Helmstaedter, M., Herculano, S., Hilscher, M. M., Hirase, Hajime, Hjerling-leffler, J., Hodge, R., Huang, J., Huda, R., Khodosevich, Konstantin, Kiehn, Ole, Koch, H., Kuebler, E. S., Kühnemund, M., Larrañaga, P., Lelieveldt, B., Louth, E. L., Lui, J. H., Mansvelder, H. D., Marin, O., Martinez-trujillo, J., Moradi Chameh, H., Nath, A., Nedergaard, M., Němec, P., Ofer, N., Pfisterer, U. G., Pontes, S., Redmond, W., Rossier, J., Sanes, J. R., Scheuermann, R., Serrano-saiz, E., Steiger, J. F., Somogyi, P., Tamás, G., Tolias, A. S., Tosches, M. A., García, M. T., Vieira, H. M., Wozny, C., Wuttke, T. V., Yong, L., Yuan, J., Zeng, H. & Lein, E., 2020, In: Nature Neuroscience. 23, p. 1456-1468 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)

    Hildebrand, F., Ebersbach, T., Nielsen, H. B., Li, X., Sonne, Si Brask, dos Santos, M. B. Q., Dimitrov, P., Madsen, L., Qin, J., Wang, J., Raes, J., Kristiansen, Karsten & Licht, T. R., 2012, In: B M C Genomics. 13, 514, 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A comparison of isolated circulating tumor cells and tissue biopsies using whole-genome sequencing in prostate cancer

    Jiang, R., Lu, Y-T., Ho, H., Li, B., Chen, J-F., Lin, M., Li, F., Wu, K., Wu, H., Lichterman, J., Wan, H., Lu, C-L., OuYang, W., Ni, M., Wang, L., Li, G., Lee, T., Zhang, X., Yang, J., Rettig, M. & 9 others, Chung, L. W. K., Yang, H., Li, K., Hou, Y., Tseng, H., Hou, S., Xu, X., Wang, J. & Posadas, E. M., 2015, In: OncoTarget. 6, 42, p. 44781-44793 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

    Su, Z., Labaj, P. P., Li, S., Thierry-Mieg, J., Thierry-Mieg, D., Shi, W., Wang, C., Schroth, G. P., Setterquist, R. A., Thompson, J. F., Jones, W. D., Xiao, W., Xu, W., Jensen, R. V., Kelly, R., Xu, J., Conesa, A., Furlanello, C., Gao, H., Hong, H. & 142 others, Jafari, N., Letovsky, S., Liao, Y., Lu, F., Oakeley, E. J., Peng, Z., Praul, C. A., Santoyo-Lopez, J., Scherer, A., Shi, T., Smyth, G. K., Staedtler, F., Sykacek, P., Tan, X., Thompson, E. A., Vandesompele, J., Wang, M. D., Wang, J., Wolfinger, R. D., Zavadil, J., Auerbach, S. S., Bao, W., Binder, H., Blomquist, T., Brilliant, M. H., Bushel, P. R., Cain, W., Catalano, J. G., Chang, C., Chen, T., Chen, G., Chen, R., Chierici, M., Chu, T., Clevert, D., Deng, Y., Derti, A., Devanarayan, V., Dong, Z., Dopazo, J., Du, T., Fang, H., Fang, Y., Fasold, M., Fernandez, A., Fischer, M., Furio-Tari, P., Fuscoe, J. C., Caimet, F., Gaj, S., Gandara, J., Gao, H., Ge, W., Gondo, Y., Gong, B., Gong, M., Gong, Z., Green, B., Guo, C., Guo, L., Guo, L., Hadfield, J., Hellemans, J., Hochreiter, S., Jia, M., Jian, M., Johnson, C. D., Kay, S., Kleinjans, J., Lababidi, S., Levy, S., Li, Q., Li, L., Li, L., Li, P., Li, Y., Li, H., Li, J., Li, S., Lin, S. M., Lopez, F. J., Lu, X., Luo, H., Ma, X., Meehan, J., Megherbi, D. B., Mei, N., Mu, B., Ning, B., Pandey, A., Perez-Florido, J., Perkins, R. G., Peters, R., Phan, J. H., Pirooznia, M., Qian, F., Qing, T., Rainbow, L., Rocca-Serra, P., Sambourg, L., Sansone, S., Schwartz, S., Shah, R., Shen, J., Smith, T. M., Stegle, O., Stralis-Pavese, N., Stupka, E., Suzuki, Y., Szkotnicki, L. T., Tinning, M., Tu, B., van Deft, J., Vela-Boza, A., Venturini, E., Walker, S. J., Wan, L., Wang, W., Wang, J., Wang, J., Wieben, E. D., Willey, J. C., Wu, P., Xuan, J., Yang, Y., Ye, Z., Yin, Y., Yu, Y., Yuan, Y., Zhang, J., Zhang, K. K., Zhang, W., Zhang, W., Zhang, Y., Zhao, C., Zheng, Y., Zhou, Y., Zumbo, P., Tong, W., Kreil, D. P., Mason, C. E. & Shi, L., 2014, In: Nature Biotechnology. 32, 9, p. 903-914 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects

    Vahidi, O., Kwok, K. E., Gopaluni, R. B. & Knop, Filip Krag, 2016, In: Medical & Biological Engineering & Computing. 54, 9, p. 1383-1398 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A comprehensive map of human glucokinase variant activity

    Gersing, S., Cagiada, Matteo, Gebbia, M., Gjesing, A. P., Coté, A. G., Seesankar, G., Li, R., Tabet, D., Weile, J., Stein, Amelie, Gloyn, A. L., Hansen, Torben, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Genome Biology. 24, 1, 23 p., 97.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links

    Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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