- 2023
- Published
Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner
Saenz, C., Fang, Q., Gnanasekaran, Thiyagarajan, Trammell, Sam, Buijink, Jesse A., Pisano, P., Wierer, M., Moens, F., Lengger, B., Brejnrod, A. & Arumugam, Mani, 2023, In: Microbiology Spectrum. 11, 5, p. 1-18 e0393322.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De-novo reconstruction and identification of transcriptional gene regulatory network modules differentiating single-cell clusters
Oubounyt, M., Elkjaer, M. L., Laske, T., Grønning, Alexander GB, Moeller, M. J. & Baumbach, J., 2023, In: NAR Genomics and Bioinformatics. 5, 1, 17 p., lqad018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mycobacterium tuberculosis Requires the Outer Membrane Lipid Phthiocerol Dimycocerosate for Starvation-Induced Antibiotic Tolerance
Block, A. M., Namugenyi, S. B., Palani, Nagendra Prasad, Brokaw, A. M., Zhang, L., Beckman, K. B. & Tischler, A. D., 2023, In: mSystems. 8, 1, 19 p., e0069922.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Danish national, multicentre evaluation of the new donor vigilance system among different staff groups
Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2023, In: Vox Sanguinis. 118, 2, p. 121-127Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk
Aglago, E. K., Kim, A., Lin, Y., Qu, C., Evangelou, M., Ren, Y., Morrison, J., Albanes, D., Arndt, V., Barry, E. L., Baurley, J. W., Berndt, S. I., Bien, S. A., Bishop, D. T., Bouras, E., Brenner, H., Buchanan, D. D., Budiarto, A., Carreras-Torres, R., Casey, G. & 80 others, , 2023, In: Cancer Research. 83, 15, p. 2572-2583 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Homozygous Nonsense Variant in the DΥM Underlies Dyggve-Melchior-Clausen Syndrome in Large Consanguineous Family
Bakar, A., Shams, S., Bibi, N., Ullah, A., Ahmad, W., Jelani, M., Muthaffar, O. Y., Abdulkareem, A. A., Abujamel, T. S., Haque, A., Naseer, M. I. & Khan, B., 2023, In: Genes. 14, 14 p., 510.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comprehensive map of human glucokinase variant activity
Andersen, Sarah Gersing, Cagiada, Matteo, Gebbia, M., Gjesing, A. P., Coté, A. G., Seesankar, G., Li, R., Tabet, D., Weile, J., Stein, Amelie, Gloyn, A. L., Hansen, Torben, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Genome Biology. 24, 1, 23 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A literature review of evidence for primary prevention of overweight and obesity in healthy weight children and adolescents: A report produced by a working group of the Danish Council on Health and Disease Prevention
Olsen, N. J., Østergaard, J. N., Bjerregaard, L. G., Høy, T. V., Kierkegaard, L., Michaelsen, Kim F., Sørensen, Thorkild I.A., Grønbæk, M. K., Bruun, J. M. & Heitmann, Berit, 2023, In: Obesity Reviews. 25, 1, 10 p., e13641.Research output: Contribution to journal › Review › Research › peer-review
- Published
A novel homozygous nonsense mutation in NECTIN4 gene in a Pakistani family with ectodermal dysplasia syndactyly syndrome 1
Hajra, B., Abdullah, Bibi, N., Syed, F., Ullah, A., Ahmad, W. & Umm-e-Kalsoom, 2023, In: Anais Brasileiros de Dermatologia. 98, 5, p. 580-586 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
Thuesen, A. C. B., Stæger, F. F., Kaci, A., Solheim, M. H., Aukrust, I., Jørsboe, E., Santander, C. G., Andersen, M. K., Li, Z., Gilly, A., Stinson, S. E., Gjesing, A. P., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Bjørkhaug, L., Njølstad, P. R. & 3 others, , 2023, In: The Lancet Regional Health - Europe. 24, 12 p., 100529.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A second update on mapping the human genetic architecture of COVID-19
Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, , 2023, In: Nature. 621, 7977, p. E7-E26 23 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development
Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies
Li, X., Chen, H., Selvaraj, M. S., Van Buren, E., Zhou, H., Wang, Y., Sun, R., McCaw, Z. R., Yu, Z., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Brody, J. A., Cade, B. E., Carson, A. P., Carlson, J. C., Chami, N., Chen, Y-D. I. & 31 others, , 2023, bioRxiv, 71 p.Research output: Working paper › Preprint › Research
- Published
AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion
Kneppers, A., Ben Larbi, S., Theret, M., Saugues, A., Dabadie, C., Gsaier, L., Ferry, A., Rhein, P., Gondin, J., Sakamoto, Kei & Mounier, R., 2023, In: iScience. 26, 12, 17 p., 108343.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss
Christiansen, Malene Revsbech, Kilpeläinen, Tuomas O. & McCaffery, J. M., 2023, In: Diabetes. 72, 10, p. 1424-1432 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70-deficient mice with a human-like bile acid composition
Sjöland, W., Wahlström, A., Makki, K., Schöler, M., Molinaro, A., Olsson, L., Greiner, T. U., Caesar, R., de Boer, J. F., Kuipers, F., Bäckhed, F. & Marschall, H. U., 2023, In: Clinical Science. 137, 13, p. 995-1011 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes
Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice
Correia, C. M., Præstholm, S. M., Havelund, J. F., Boel, Felix, Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Zach, Heeren, J., Brewer, J., Larsen, Steen, Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, In: Endocrinology. 164, 10, p. 1-17 164.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots
Palani, Nagendra Prasad, Horvath, C., Timshel, P. N., Folkertsma, P., Grønning, Alexander GB, Henriksen, T. I., Peijs, Lone, Jensen, V. H., Sun, W., Jespersen, N. Z., Wolfrum, C., Pers, Tune H, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2023, In: Nature Metabolism. 5, 6, p. 996-1013 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction
Thirion, F., Speyer, H., Hansen, T. H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Plaza Oñate, F., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S. K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O. & 3 others, , 2023, In: Biological Psychiatry Global Open Science. 3, 2, p. 283-291 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acid homeostasis is a target of metformin therapy
Forteath, C., Mordi, I., Nisr, R., Gutierrez-Lara, E. J., Alqurashi, N., Phair, I. R., Cameron, A. R., Beall, C., Bahr, I., Mohan, M., Wong, A. K. F., Dihoum, A., Mohammad, A., Palmer, C. N. A., Lamont, D., Sakamoto, Kei, Viollet, B., Foretz, M., Lang, C. C. & Rena, G., 2023, In: Molecular Metabolism. 74, 16 p., 101750.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adiposity force induces obesity in humans independently of a normal energy balance system-a thought experiment
Sørensen, Thorkild I.A., 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 9 p., 20220203.Research output: Contribution to journal › Review › Research › peer-review
- Published
An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents
Huang, Yun, Stinson, Sara, Juel, H. B., Lund, M. A. V., Holm, Louise Aas, Fonvig, Cilius Esmann, Nielsen, T., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, M., Chabanova, E., Thomsen, Henrik S., Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An automated workflow for multi-omics screening of microbial model organisms
Donati, S., Mattanovich, M., Hjort, P., Jacobsen, S. A. B., Blomquist, S. D., Mangaard, D., Gurdo, N., Pastor, F. P., Maury, J., Hanke, R., Herrgård, M. J., Wulff, T., Jakočiūnas, T., Nielsen, L. K. & McCloskey, D., 2023, In: npj Systems Biology and Applications. 9, 12 p., 14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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