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Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification
Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.Research output: Contribution to journal › Review › Research › peer-review
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A second update on mapping the human genetic architecture of COVID-19
Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, , 2023, In: Nature. 621, 7977, p. E7-E26 23 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C. & 519 others, , 2022, In: Genome Biology. 23, 1, 42 p., 268.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
Million Veteran Program, M. V. P., LifeLines Cohort Study, L. C. S., CHARGE Consortium, C. C. & ICBP Consortium, I. C., 2024, In: Nature Genetics. 56, 5, p. 778-791Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy
Kiryluk, K., Sanchez-Rodriguez, E., Zhou, X. J., Zanoni, F., Liu, L., Mladkova, N., Khan, A., Marasa, M., Zhang, J. Y., Balderes, O., Sanna-Cherchi, S., Bomback, A. S., Canetta, P. A., Appel, G. B., Radhakrishnan, J., Trimarchi, H., Sprangers, B., Cattran, D. C., Reich, H., Pei, Y. & 168 others, , 2023, In: Nature Genetics. 55, 7, p. 1091-1105 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discrepancy between predicted and measured exercise intensity for eliciting the maximal rate of lipid oxidation
Kittrell, H. D., DiMenna, F. J., Arad, A. D., Oh, W., Hofer, I., Walker, R. W., Loos, Ruth, Albu, J. B. & Nadkarni, G. N., 2023, In: Nutrition, Metabolism and Cardiovascular Diseases. 33, 11, p. 2189-2198Research output: Contribution to journal › Journal article › Research › peer-review
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Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors
Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, , 2024, In: Communications Medicine. 4, 15 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
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GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification
Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, , 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancestral diversity in lipoprotein(a) studies helps address evidence gaps
Lee, M. P., Dimos, S. F., Raffield, L. M., Wang, Z., Ballou, A. F., Downie, C. G., Arehart, C. H., Correa, A., De Vries, P. S., Du, Z., Gignoux, C. R., Gordon-Larsen, P., Guo, X., Haessler, J., Howard, A. G., Hu, Y., Kassahun, H., Kent, S. T., Lopez, J. A. G., Monda, K. L. & 14 others, , 2023, In: Open Heart. 10, 2, 11 p., e002382.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Lennon, N. J., Kottyan, L. C., Kachulis, C., Abul-Husn, N. S., Arias, J., Belbin, G., Below, J. E., Berndt, S. I., Chung, W. K., Cimino, J. J., Clayton, E. W., Connolly, J. J., Crosslin, D. R., Dikilitas, O., Velez Edwards, D. R., Feng, Q. P., Fisher, M., Freimuth, R. R., Ge, T., Glessner, J. T. & 59 others, , 2024, In: Nature Medicine. 30, 2, p. 480-487 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Developmental language disorder – a comprehensive study of more than 46,000 individuals
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A saturated map of common genetic variants associated with human height
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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
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An integrative framework to prioritize genes in more than 500 loci associated with body mass index
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