Loos Group

  1. Published

    Understanding risk and causal mechanisms for developing obesity in infants and young children: A National Institutes of Health workshop

    Aagaard, K. M., Barkin, S. L., Burant, C. F., Carnell, S., Demerath, E., Donovan, S. M., Eneli, I., Francis, L. A., Gilbert-Diamond, D., Hivert, M. F., LeBourgeois, M. K., Loos, R. J. F., Lumeng, J. C., Miller, A. L., Okely, A. D., Osganian, S. K., Ramirez, A. G., Trasande, L., Van Horn, L. V., Wake, M. & 2 others, Wright, R. J. & Yanovski, S. Z., 2024, In: Obesity Reviews. 25, 4, 21 p., e13690.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Published

    The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study

    Abdulkadir, M., Hübel, C., Herle, M., Loos, Ruth, Breen, G., Bulik, C. M. & Micali, N., 2022, In: American Journal of Human Genetics. 109, 7, p. 1242-1254 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

    Aglago, E. K., Kim, A., Lin, Y., Qu, C., Evangelou, M., Ren, Y., Morrison, J., Albanes, D., Arndt, V., Barry, E. L., Baurley, J. W., Berndt, S. I., Bien, S. A., Bishop, D. T., Bouras, E., Brenner, H., Buchanan, D. D., Budiarto, A., Carreras-Torres, R., Casey, G. & 80 others, Cenggoro, T. W., Chan, A. T., Chang-Claude, J., Chen, X., Conti, D. V., Devall, M., Díez Obrero, Virginia, Dimou, N., Drew, D., Figueiredo, J. C., Gallinger, S., Giles, G. G., Gruber, S. B., Gsur, A., Gunter, M. J., Hampel, H., Harlid, S., Hidaka, A., Harrison, T. A., Hoffmeister, M., Huyghe, J. R., Jenkins, M. A., Jordahl, K., Joshi, A. D., Kawaguchi, E. S., Keku, T. O., Kundaje, A., Larsson, S. C., Marchand, L. L., Lewinger, J. P., Li, L., Lynch, B. M., Mahesworo, B., Mandic, M., Obón-Santacana, M., Moreno, V., Murphy, N., Nan, H., Nassir, R., Newcomb, P. A., Ogino, S., Ose, J., Pai, R. K., Palmer, J. R., Papadimitriou, N., Pardamean, B., Peoples, A. R., Platz, E. A., Potter, J. D., Prentice, R. L., Rennert, G., Ruiz-Narvaez, E., Sakoda, L. C., Scacheri, P. C., Schmit, S. L., Schoen, R. E., Shcherbina, A., Slattery, M. L., Stern, M. C., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Tian, Y., Ulrich, C. M., van Duijnhoven, F. J., Van Guelpen, B., Visvanathan, K., Vodicka, P., Wang, J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Zemlianskaia, N., Hsu, L., Gauderman, W. J., Peters, U., Tsilidis, K. K. & Campbell, P. T., 2023, In: Cancer Research. 83, 15, p. 2572-2583 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Approaches to addressing the rise in obesity levels

    Apovian, C. M., Guo, X. R., Hawley, J. A., Karmali, S., Loos, Ruth & Waterlander, W. E., 2023, In: Nature Reviews Endocrinology. 19, p. 76-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Clinical Characterization of Copy Number Variants Associated with Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank

    Birnbaum, R., Mahjani, B., Loos, Ruth & Sharp, A. J., 2022, In: JAMA Psychiatry. 79, 3, p. 250-259

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

    Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, Magnusson, O. T., Melsted, P., Moore, K. H. S., Oddsson, A., Olason, P. I., Sigurdsson, A., Banasik, Karina, Brunak, Søren, Didriksen, Maria, Kogelman, L. J. A., Nielsen, K. R., Sørensen, E., Pedersen, Ole Birger Vesterager, Ullum, H., Bay, J., Burgdorf, Kristoffer Sølvsten, Dowsett, J., Hjalgrim, Henrik, Jacobsen, R. L., Louloudis, Ioannis, Lundgaard, Agnete Troen, Mikkelsen, Christina, Nyegaard, Mette, Henriksen, Alexander Pil, Werge, Thomas, Westergaard, David, Olesen, Jes, Ostrowski, Sisse Rye, Hansen, Thomas Folkmann & DBDS Genetic Consortium, D. G. C., 2023, In: Nature Genetics. 55, 11, p. 1843-1853

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort

    Bjørnsbo, K. S., Brøns, C., Aadahl, M., Kampmann, F. B., Friis Bryde Nielsen, C., Lundbergh, B., Christensen, R. W., Kårhus, L. L., Madsen, A. L., Hansen, C. S., Nørgaard, K., Jørgensen, N. R., Suetta, C., Kjaer, M., Grarup, N., Kanters, J., Larsen, M., Køber, L., Kofoed, K. F., Loos, R. & 3 others, Hansen, Torben, Linneberg, Allan René & Vaag, Allan, 2024, In: BMJ Open. 14, 1, 10 p., e078501.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paperPreprintResearch

  10. Published

    Child-to-adult body size change and risk of type 2 diabetes and cardiovascular disease

    Carrasquilla, Germán D., Ängquist, Lars, Sørensen, Thorkild I.A., Kilpeläinen, Tuomas O. & Loos, Ruth, 2024, In: Diabetologia. 67, p. 864–873 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A genomic mutational constraint map using variation in 76,156 human genomes

    Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., Poterba, T., Wilson, M. W., Tarasova, Y., Phu, W., Grant, R., Yohannes, M. T., Koenig, Z., Farjoun, Y., Banks, E., Donnelly, S. & 18 others, Gabriel, S., Gupta, N., Ferriera, S., Tolonen, C., Novod, S., Bergelson, L., Roazen, D., Ruano-Rubio, V., Covarrubias, M., Llanwarne, C., Petrillo, N., Wade, G., Jeandet, T., Munshi, R., Tibbetts, K., Loos, Ruth, Karczewski, K. J. & Genome Aggregation Database Consortium, G. A. D. C., 2024, In: Nature. 625, 7993, p. 92-100 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms

    Deutsch, A. J., Stalbow, L., Majarian, T. D., Mercader, J. M., Manning, A. K., Florez, J. C., Loos, Ruth & Udler, M. S., 2023, In: Diabetes Care. 46, 4, p. 794-800 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published
  14. Published

    Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium

    Fernández-Rhodes, L., Graff, M., Buchanan, V. L., Justice, A. E., Highland, H. M., Guo, X., Zhu, W., Chen, H. H., Young, K. L., Adhikari, K., Palmer, N. D., Below, J. E., Bradfield, J., Pereira, A. C., Glover, L. S., Kim, D., Lilly, A. G., Shrestha, P., Thomas, A. G., Zhang, X. & 96 others, Chen, M., Chiang, C. W. K., Pulit, S., Horimoto, A., Krieger, J. E., Guindo Martínez, Marta, Preuss, M., Schumann, C., Smit, R. A. J., Torres-Mejía, G., Acuña-Alonzo, V., Bedoya, G., Bortolini, M. C., Canizales-Quinteros, S., Gallo, C., González-José, R., Poletti, G., Rothhammer, F., Hakonarson, H., Igo, R., Adler, S. G., Iyengar, S. K., Nicholas, S. B., Gogarten, S. M., Isasi, C. R., Papnicolaou, G., Stilp, A. M., Qi, Q., Kho, M., Smith, J. A., Langefeld, C. D., Wagenknecht, L., Mckean-Cowdin, R., Gao, X. R., Nousome, D., Conti, D. V., Feng, Y., Allison, M. A., Arzumanyan, Z., Buchanan, T. A., Ida Chen, Y. D., Genter, P. M., Goodarzi, M. O., Hai, Y., Hsueh, W., Ipp, E., Kandeel, F. R., Lam, K., Li, X., Nadler, J. L., Raffel, L. J., Roll, K., Sandow, K., Tan, J., Taylor, K. D., Xiang, A. H., Yao, J., Audirac-Chalifour, A., de Jesus Peralta Romero, J., Hartwig, F., Horta, B., Blangero, J., Curran, J. E., Duggirala, R., Lehman, D. E., Puppala, S., Fejerman, L., John, E. M., Aguilar-Salinas, C., Burtt, N. P., Florez, J. C., García-Ortíz, H., González-Villalpando, C., Mercader, J., Orozco, L., Tusié-Luna, T., Blanco, E., Gahagan, S., Cox, N. J., Hanis, C., Butte, N. F., Cole, S. A., Comuzzie, A. G., Voruganti, V. S., Rohde, R., Wang, Y., Sofer, T., Ziv, E., Grant, S. F. A., Ruiz-Linares, A., Rotter, J. I., Haiman, C. A., Parra, E. J., Cruz, M., Loos, Ruth & North, K. E., 2022, In: Human Genetics and Genomics Advances. 3, 2, 21 p., 100099.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Early-life residential green spaces and traffic exposure in association with young adult body composition: a longitudinal birth cohort study of twins

    Figaroa, M. N. S., Gielen, M., Casas, L., Loos, Ruth, Derom, C., Weyers, S., Nawrot, T. S., Zeegers, M. P. & Bijnens, E. M., 2023, In: Environmental Health. 22, 13 p., 18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    New insights in the mechanisms of weight-loss maintenance: Summary from a Pennington symposium

    Flanagan, E. W., Spann, R., Berry, S. E., Berthoud, H. R., Broyles, S., Foster, G. D., Krakoff, J., Loos, Ruth, Lowe, M. R., Ostendorf, D. M., Powell-Wiley, T. M., Redman, L. M., Rosenbaum, M., Schauer, P. R., Seeley, R. J., Swinburn, B. A., Hall, K. & Ravussin, E., 2023, In: Obesity. 31, 12, p. 2895-2908

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting: Design and methodology

    Freiberg, J., Rovelt, J., Gazzard, G., Cour, M. L., Kolko, M., Torp‐Pedersen, C., Benn, M., Brunak, S., Cour, M. L., Tolstrup, J., Toft‐Petersen, A. P., Burgdorf, K. S., Banasik, K., Chmura, P. J., Freiberg, J., Rovelt, J., Thornit, D. N., Foster, P., Gazzard, G., Crabb, D. P. & 4 others, Viswanathan, A., Barman, Sarah, Owen, C. G. & Rudnicka, A. R., 2024, In: Acta Ophthalmologica. 102, 1, p. 80-90 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations

    Gerhart-Hines, Zach & Loos, Ruth, 2023, In: Current Opinion in Genetics and Development. 83, 102117.

    Research output: Contribution to journalEditorialResearch

  19. Published

    Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

    Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., Marasa, M. & 60 others, Shang, N., Cohen, D. J., Crew, R. J., Morello, W., Canetta, P., Radhakrishnan, J., Martino, J., Liu, Q., Chung, W. K., Espinoza, A., Luo, Y., Wei, W., Feng, Q., Weng, C., Fang, Y., Kullo, I. J., Naderian, M., Limdi, N., Irvin, M. R., Tiwari, H., Mohan, S., Rao, M., Dube, G. K., Chaudhary, N. S., Gutiérrez, O. M., Judd, S. E., Cushman, M., Lange, L. A., Lange, E. M., Bivona, D. L., Verbitsky, M., Winkler, C. A., Kopp, J. B., Santoriello, D., Batal, I., Pinheiro, S. V. B., Oliveira, E. A., Simoes e Silva, A. C., Pisani, I., Fiaccadori, E., Lin, F., Gesualdo, L., Amoroso, A., Ghiggeri, G. M., D’Agati, V. D., Magistroni, R., Kenny, E. E., Loos, Ruth, Montini, G., Hildebrandt, F., Paul, D. S., Petrovski, S., Goldstein, D. B., Kretzler, M., Gbadegesin, R., Gharavi, A. G., Kiryluk, K., Sampson, M. G., Pollak, M. R. & Sanna-Cherchi, S., 2023, In: Nature Communications. 14, 8 p., 7836.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The energy balance model of obesity: beyond calories in, calories out

    Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, Ruth, Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R. & Tobias, D. K., 2022, In: American Journal of Clinical Nutrition. 115, 5, p. 1243-1254 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores

    Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A. C., Carson, A. P., Haring, B., Mitchel, B. D., Psaty, B. M., Jaeger, B. C., Gu, C. C., Kooperberg, C., Levy, D., Lloyd-Jones, D., Choi, E., Brody, J. A., Smith, J. A., Rotter, J. I., Moll, M. & 18 others, Fornage, M., Simon, N., Castaldi, P., Casanova, R., Chung, R., Kaplan, R., Loos, Ruth, Kardia, S. L. R., Rich, S. S., Redline, S., Kelly, T., O'Connor, T., Zhao, W., Kim, W., Guo, X., Chen, Y. D. I., Sofer, T. & Trans-Omics in Precision Medicine Consortium, T. I. P. M. C., 2023, medRxiv, 41 p.

    Research output: Working paperPreprintResearch

  22. Published

    Genomics and phenomics of body mass index reveals a complex disease network

    Huang, J., Huffman, J. E., Huang, Y., Do Valle, Í., Assimes, T. L., Raghavan, S., Voight, B. F., Liu, C., Barabási, A. L., Huang, R. D. L., Hui, Q., Nguyen, X. M. T., Ho, Y. L., Djousse, L., Lynch, J. A., Vujkovic, M., Tcheandjieu, C., Tang, H., Damrauer, S. M., Reaven, P. D. & 19 others, Miller, D., Phillips, L. S., Ng, M. C. Y., Graff, M., Haiman, C. A., Loos, Ruth, North, K. E., Yengo, L., Smith, G. D., Saleheen, D., Gaziano, J. M., Rader, D. J., Tsao, P. S., Cho, K., Chang, K. M., Wilson, P. W. F., Sun, Y. V., O’Donnell, C. J. & VA Million Veteran Program, V. M. V. P., 2022, In: Nature Communications. 13, 1, 10 p., 7973.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data

    Huang, L., Rosen, J. D., Sun, Q., Chen, J., Wheeler, M. M., Zhou, Y., Min, Y. I., Kooperberg, C., Conomos, M. P., Stilp, A. M., Rich, S. S., Rotter, J. I., Manichaikul, A., Loos, R. J. F., Kenny, E. E., Blackwell, T. W., Smith, A. V., Jun, G., Sedlazeck, F. J., Metcalf, G. & 6 others, Boerwinkle, E., Raffield, L. M., Reiner, A. P., Auer, P. L., Li, Y. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2022, In: American Journal of Human Genetics. 109, 6, p. 1175-1181 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

    Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, Ruth, Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher-Hoch, S. P., Ordoñez, M. L., Meigs, J., Baier, L. J., González-Villalpando, C., González-Villalpando, M. E., Orozco, L., García-García, L. & Mexican Biobank, M. B., 2023, In: Diabetologia. 66, p. 1273-1288 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

    Hughes, O., Bentley, A. R., Breeze, C. E., Aguet, F., Xu, X., Nadkarni, G., Sun, Q., Lin, B. M., Gilliland, T., Meyer, M. C., Du, J., Raffield, L. M., Kramer, H., Morton, R. W., Gouveia, M. H., Atkinson, E. G., Valladares-Salgado, A., Wacher-Rodarte, N., Dueker, N. D., Guo, X. & 54 others, Hai, Y., Adeyemo, A., Best, L. G., Cai, J., Chen, G., Chong, M., Doumatey, A., Eales, J., Goodarzi, M. O., Ipp, E., Irvin, M. R., Jiang, M., Jones, A. C., Kooperberg, C., Krieger, J. E., Lange, E. M., Lanktree, M. B., Lash, J. P., Lotufo, P. A., Loos, Ruth, Ha My, V. T., Peralta-Romero, J., Qi, L., Raffel, L. J., Rich, S. S., Rodriquez, E. J., Tarazona-Santos, E., Taylor, K. D., Umans, J. G., Wen, J., Young, B. A., Yu, Z., Zhang, Y., Ida Chen, Y. D., Rundek, T., Rotter, J. I., Cruz, M., Fornage, M., Lima-Costa, M. F., Pereira, A. C., Paré, G., Natarajan, P., Cole, S. A., Carson, A. P., Lange, L. A., Li, Y., Perez-Stable, E. J., Do, R., Charchar, F. J., Tomaszewski, M., Mychaleckyj, J. C., Rotimi, C., Morris, A. P. & Franceschini, N., 2024, In: Cell Genomics. 4, 1, 13 p., 100468.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 3 Next