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Revisiting How the Brain Senses Glucose-And Why
Bentsen, M. A., Mirzadeh, Z. & Schwartz, M. W., 2019, In: Cell Metabolism. 29, 1, p. 11-17Research output: Contribution to journal › Review › Research › peer-review
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RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › Research › peer-review
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Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission
Brown, Jenny, Bentsen, M. A., Belmont-Rausch, Dylan Matthew, Phan, B. A., Wieck, D., Wasanwala, H., Matsen, M. E., Acharya, N., Richardson, N. E., Zhao, X., Zhai, P., Secher, A., Morton, G. J., Pers, Tune H, Schwartz, M. W. & Scarlett, J. M., 2021, In: iScience. 24, 9, 19 p., 102944.Research output: Contribution to journal › Journal article › Research › peer-review
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Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, , 2022, In: Biological Psychiatry. 91, 1, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
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Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex
Ludwig, M. Q., Todorov, Petar Vladimirov, Egerod, Kristoffer Lihme, Olson, D. P. & Pers, Tune H, 2021, In: Diabetes. 70, 9, p. 1945-1955 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis
Fred, Rikard Göran, Steen Pedersen, J., Thompson, J. J., Lee, J., Timshel, P. N., Stender, S., Rygg, M. O., Gluud, Lise Lotte, Bjerregaard Kristiansen, V., Bendtsen, Flemming, Hansen, Torben & Pers, Tune H, 2022, In: Scientific Reports. 12, 1, 13 p., 13484.Research output: Contribution to journal › Journal article › Research › peer-review
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Sustained inhibition of NPY/AgRP neuronal activity by FGF1
Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, Jenny, Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., 2022, In: JCI insight. 7, 17, 11 p., e160891.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
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The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, , 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The developing Entorhinal Cortex – a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
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The developing Entorhinal cortex - a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
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The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice
Fan, Y., Støving, R. K., Berreira Ibraim, S., Hyötyläinen, T., Thirion, F., Arora, T., Lyu, L., Stankevic, E., Hansen, T. H., Déchelotte, P., Sinioja, T., Ragnarsdottir, O., Pons, N., Galleron, N., Quinquis, B., Levenez, F., Roume, H., Falony, G., Vieira-Silva, S., Raes, J. & 6 others, , 2023, In: Nature Microbiology. 8, p. 787–802Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota in multiple sclerosis varies with disease activity
Thirion, F., Sellebjerg, Finn Thorup, Fan, Yong, Lyu, Liwei, Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, Evelina, Søndergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., drb459, drb459, Hansen, Torben, Brix, S., Oturai, A., Sørensen, Per Soelberg, Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Genome Medicine. 15, 17 p., 1.Research output: Contribution to journal › Journal article › Research › peer-review
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Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111Research output: Contribution to journal › Letter › Research › peer-review
- Published
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, , 2020, In: Nature Communications. 11, 1, 4458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
microRNA-based signatures obtained from endometrial fluid identify implantative endometrium
Ibañez-Perez, J., Díaz-Nuñez, M., Clos-García, M., Lainz, L., Iglesias, M., Díez-Zapirain, M., Rabanal, A., Bárcena, L., González, M., Lozano, J. J., Marigorta, U. M., González, E., Royo, F., Aransay, A. M., Subiran, N., Matorras, R. & Falcón-Pérez, J. M., 2022, In: Human Reproduction. 37, 10, p. 2375-2391 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
scVAE: variational auto-encoders for single-cell gene expression data
Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
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Exposure to environmental toxicants is associated with gut microbiome dysbiosis, insulin resistance and obesity
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