- 2022
- Published
A single-cell atlas of human and mouse white adipose tissue
Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., McGonagle, E., Strobel, S., Laber, S., Agrawal, S., Westcott, G. P., Kar, A., Veregge, M. L., Gulko, A., Srinivasan, H., Kramer, Z. & 18 others, , 2022, In: Nature. 603, p. 926-933Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis
Fred, Rikard Göran, Steen Pedersen, J., Thompson, J. J., Lee, J., Timshel, P. N., Stender, S., Rygg, M. O., Gluud, Lise Lotte, Bjerregaard Kristiansen, V., Bendtsen, Flemming, Hansen, Torben & Pers, Tune H, 2022, In: Scientific Reports. 12, 1, 13 p., 13484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbiome and metabolome features of the cardiometabolic disease spectrum
Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. & 44 others, , 2022, In: Nature Medicine. 28, 2, p. 303-314Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained inhibition of NPY/AgRP neuronal activity by FGF1
Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, Jenny, Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., 2022, In: JCI insight. 7, 17, 11 p., e160891.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
microRNA-based signatures obtained from endometrial fluid identify implantative endometrium
Ibañez-Perez, J., Díaz-Nuñez, M., Clos-García, M., Lainz, L., Iglesias, M., Díez-Zapirain, M., Rabanal, A., Bárcena, L., González, M., Lozano, J. J., Marigorta, U. M., González, E., Royo, F., Aransay, A. M., Subiran, N., Matorras, R. & Falcón-Pérez, J. M., 2022, In: Human Reproduction. 37, 10, p. 2375-2391 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits
Merino, J., Dashti, H. S., Sarnowski, C., Lane, J. M., Todorov, Petar Vladimirov, Udler, M. S., Song, Y., Wang, H., Kim, J., Tucker, C., Campbell, J., Tanaka, T., Chu, A. Y., Tsai, L., Pers, Tune H, Chasman, D., Rutter, M. K., Dupuis, J., Florez, J. C. & Saxena, R., 2022, In: Nature Human Behaviour. 6, p. 155-163 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the relationship between migraine risk and brain structure using genetic data
International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, , 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causes of Outcome Learning: a causal inference-inspired machine learning approach to disentangling common combinations of potential causes of a health outcome
Rieckmann, Andreas, Dworzynski, P., Arras, L., Lapuschkin, S., Samek, W., Arah, O. A., Rod, Naja Hulvej & Ekstrøm, Claus Thorn, 2022, In: International Journal of Epidemiology. 51, 5, p. 1622–1636 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, , 2022, In: Brain. 145, 2, p. 555–568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, , 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965
Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, , 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission
Brown, Jenny, Bentsen, M. A., Belmont-Rausch, Dylan Matthew, Phan, B. A., Wieck, D., Wasanwala, H., Matsen, M. E., Acharya, N., Richardson, N. E., Zhao, X., Zhai, P., Secher, A., Morton, G. J., Pers, Tune H, Schwartz, M. W. & Scarlett, J. M., 2021, In: iScience. 24, 9, 19 p., 102944.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, , 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis
Johnsen, Cecilie Hundahl, Kotzbeck, P., Burm, Hayley Beth, Christiansen, S. H., Pedersen, Lola Julie Torz, zmw799, zmw799, Madsen, M. P., Ratner, C., Serup, A. K., Thompson, J. J., Eichmann, T. O., Pers, Tune H, Woldbye, David Paul Drucker, Piomelli, D., Kiens, Bente, Zechner, R., Skov, Louise Julie & Holst, Birgitte, 2021, In: Molecular Metabolism. 47, 16 p., 101174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies
Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genetic map of the mouse dorsal vagal complex and its role in obesity
Ludwig, M. Q., Cheng, W., Gordian, D., Lee, J., Paulsen, S. J., Hansen, S. N., Egerod, Kristoffer Lihme, Barkholt, P., Rhodes, C. J., Secher, A., Knudsen, L. B., Pyke, C., Myers, M. G. & Pers, Tune H, 2021, In: Nature Metabolism. 3, p. 530-545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex
Ludwig, M. Q., Todorov, Petar Vladimirov, Egerod, Kristoffer Lihme, Olson, D. P. & Pers, Tune H, 2021, In: Diabetes. 70, 9, p. 1945-1955 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Mills, M. C., Tropf, F. C., Brazel, D. M., van Zuydam, N., Vaez, A., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A. K., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Jan Bonder, M., Boomsma, D. I., Christiansen, M. W., Claringbould, A., Deelen, P., Esko, T., Favé, M-J. & 33 others, , 2021, In: Nature Human Behaviour. 5, p. 1717-1730Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Ni, G., Zeng, J., Revez, J. A., Wang, Y., Zheng, Z., Ge, T., Restuadi, R., Kiewa, J., Nyholt, D. R., Coleman, J. R. I., Smoller, J. W., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A. & 21 others, , 2021, In: Biological Psychiatry. 90, 9, p. 611-620Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How robust are cross-population signatures of polygenic adaptation in humans?
Refoyo Martínez, Alba, Liu, S., Jørgensen, A. M., Jin, X., Albrechtsen, Anders, Martin, A. R. & Racimo, Fernando, 2021, In: Peer Community Journal. 1, 54 p., e22.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle
Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W., Sanders, M. J. & 4 others, , 2021, In: Molecular Metabolism. 51, 18 p., 101228.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into biological mechanisms governing human ovarian ageing
Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, , 2021, In: Nature. 596, p. 393-397Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
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