Schwartz Group

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  1. 2019
  2. Published

    The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

    Rudenko, Olga, Shang, J., Munk, A., Ekberg, J. P., Petersen, N., Engelstoft, M. S., Egerod, Kristoffer Lihme, Hjorth, Siv Annegrethe, Wu, M., Feng, Y., Zhou, Y., Mokrosinski, J., Thams, P., Reimann, F., Gribble, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Treebak, Jonas Thue, Howard, A. D. & Schwartz, Thue W., 2019, In: Molecular Metabolism. 19, p. 49-64 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity

    Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1

    Lückmann, Michael, Trauelsen, Mette, Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2020
  6. Published

    Activation of metabolite receptor GPR91 promotes platelet aggregation and transcellular biosynthesis of leukotriene C4

    Tang, X., Fuchs, D., Tan, S., Trauelsen, Mette, Schwartz, Thue W., Wheelock, C. E., Li, N. & Haeggstrom, J. Z., 2020, In: Journal of Thrombosis and Haemostasis. 18, 4, p. 976-984 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Autocrine negative feed-back regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

    Husted, Anna Sofie, Ekberg, J. H., Tripp, E., Nissen, T. A. D., Meijnikman, S., O'Brien, S. L., Ulven, Trond, Acherman, Y., Bruin, S. C., Nieuwdorp, M., Gerhart-Hines, Zach, Calebiro, D., Dragsted, Lars Ove & Schwartz, Thue W., 2020, In: Molecular Metabolism. 42, 10 p., 101103.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Neurotrophic effects of vascular endothelial growth factor B and novel mimetic peptides on neurons from the central nervous system

    Dmytriyeva, O., de Diego Ajenjo, A., Jørgensen, Kathrine Lundø, Hertz, H., Rasmussen, K. K., Christiansen, A. T., Klingelhofer, J., Nielsen, A. L., Hoeber, J., Kozlova, E. N., Woldbye, David Paul Drucker & Pankratova, Stanislava, 2020, In: ACS Chemical Neuroscience. 11, 9, p. 1270–1282 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journal › Comment/debate › Research

  10. Published

    Rasal1-the missing GAP downstream of plexins

    Hoess, C., Xu, R., Swiercz, J. M., Petersen, N., Brandt, D., Lu, R., Groene, H. J., Offermanns, S. & Worzfeld, T., 2020, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 393, 1, suppl., p. S15 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2020, In: bioRxiv. 26 p.

    Research output: Contribution to journal › Journal article › Research

  12. Published

    Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands

    Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa

    Tough, I. R., Schwartz, Thue W. & Cox, H. M., 2020, In: Neurogastroenterology and Motility. 32, 12, 14 p., e13943.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Three-Dimensional Explant Platform for Studies on Choroid Plexus Epithelium

    Petersen, N., Pedersen, Lola Julie Torz, Jensen, Kristian HR, Hjortø, Gertrud Malene, Spiess, Katja & Rosenkilde, Mette, 2020, In: Frontiers in Cellular Neuroscience. 14, 11 p., 108.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Why Warburg Works: Lactate Controls Immune Evasion through GPR81

    Jørgensen, Kathrine Lundø, Trauelsen, Mette, Pedersen, Stine Helene Falsig & Schwartz, Thue W., 2020, In: Cell Metabolism. 31, 4, p. 666–668 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  16. Published

    snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

    Sun, W., Dong, H., Balaz, M., Slyper, M., Drokhlyansky, E., Colleluori, G., Giordano, A., Kovanicova, Z., Stefanicka, P., Balazova, L., Ding, L., Husted, Anna Sofie, Rudofsky, G., Ukropec, J., Cinti, S., Schwartz, Thue W., Regev, A. & Wolfrum, C., 2020, In: Nature. 587, 31 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling

    Lund, M. L., Sorrentino, G., Egerod, Kristoffer Lihme, Kroone, C., Mortensen, B., Knop, Filip Krag, Reimann, F., Gribble, F. M., Drucker, D. J., De Koning, E. J. P., Schoonjans, K., Bäckhed, F., Schwartz, Thue W. & Petersen, N., Apr 2020, In: Diabetes. 69, 4, p. 614-623 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2021
  19. Published

    A novel luminescence-based β-arrestin recruitment assay for unmodified receptors

    Pedersen, M. H., Pham, J., Mancebo, H., Inoue, A., Asher, W. B. & Javitch, J. A., 2021, In: Journal of Biological Chemistry. 296, 10 p., 100503.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study

    Van Olden, C. C., Van de Laar, A. W., Meijnikman, A. S., Aydin, O., Van Olst, N., Hoozemans, J. B., De Brauw, L. M., Bruin, S. C., Acherman, Y. I. Z., Verheij, J., Pyykko, J. E., Hagedoorn, M., Sanderman, R., Bosma, N. C., Tremaroli, V., Lundqvist, A., Olofsson, L. E., Herrema, H., Lappa, D., Hjorth, S. & 6 others, Nielsen, J., Schwartz, Thue W., Groen, A. K., Nieuwdorp, M., Backhed, F. & Gerdes, V. E. A., 2021, In: Journal of Internal Medicine. 289, 3, p. 340-354 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells

    Grunddal, Kaare Villum, Tonack, S., Egerod, Kristoffer Lihme, Thompson, J. J., Petersen, N., Engelstoft, M. S., Vagne, C., Keinse, C., Gradwohl, G., Offermanns, S. & Schwartz, Thue W., 2021, In: Molecular Metabolism. 51, 17 p., 101231.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms

    Modvig, Ida Marie, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Xu, S., Engelstoft, M. S., Egerod, Kristoffer Lihme, Schwartz, Thue W., Ørskov, Cathrine, Rosenkilde, Mette & Holst, Jens Juul, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Assays for detecting arrestin interaction with GPCRs

    Perry-Hauser, N. A., Asher, W. B., Hauge Pedersen, M. & Javitch, J. A., 2021, Biomolecular Interactions Part A. Shukla, A. K. (ed.). Academic Press, p. 43-65 23 p. (Methods in Cell Biology, Vol. 166).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  24. Published

    Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

    Baumgartner, R., Casagrande, F. B., Mikkelsen, R. B., Berg, M., Polyzos, K. A., Forteza, M. J., Arora, A., Schwartz, Thue W., Hjorth, Siv Annegrethe & Ketelhuth, D. F. J., 2021, In: Metabolites. 11, 7, 10 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Encephalopathy-causing mutations in G beta(1) (GNB1) alter regulation of neuronal GIRK channels

    Reddy, H. P., Yakubovich, D., Keren-Raifman, T., Tabak, G., Tsemakhovich, V. A., Pedersen, M. H., Shalomov, B., Colombo, S., Goldstein, D. B., Javitch, J. A., Bera, A. K. & Dascal, N., 2021, In: iScience. 24, 9, 29 p., 103018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans

    Baumgartner, R., Berg, M., Matic, L., Polyzos, K. P., Forteza, M. J., Hjorth, Siv Annegrethe, Schwartz, Thue W., Paulson-Berne, G., Hansson, G. K., Hedin, U. & Ketelhuth, D. F. J., 2021, In: Journal of Internal Medicine. 289, 1, p. 53-68 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

    Trauelsen, Mette, Hiron, T. K., Lin, D., Petersen, Jacob Emil, Breton, B., Husted, Anna Sofie, Hjorth, Siv Annegrethe, Inoue, A., Frimurer, Thomas Michael, Bouvier, M., O'Callaghan, C. A. & Schwartz, Thue W., 2021, In: Cell Reports. 35, 11, 15 p., 109246.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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