Treebak Group

  1. Published

    Hepatic NAD Metabolism Is Dysregulated By an Excessive Supply of Lipids

    Penke, M., Treebak, Jonas Thue, Schuster, S., Gorski, T., Garten, A. & Kiess, W., 2014, In: Endocrine Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia

    Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

    Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Hyperphosphorylation and low protein content of muscle glycogen synthase contribute to insulin resistance in polycystic ovary syndrome: effects of pioglitazone treatment

    Hojlund, K., Glintborg, D., Andersen, N. R., Birk, Jesper Bratz, Treebak, Jonas Thue, Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2007, In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Identification of protein phosphatase involvement in the AT2 receptor-induced activation of endothelial nitric oxide synthase

    Peluso, A., 2018, In: Clinical Science.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Impaired Insulin-Mediated Phosphorylation of Skeletal Muscle TBC1D4 at Multiple Sites in Type 2 Diabetes. Effect of Endurance Training on TBC1D4 Protein and Phosphorylation

    Vind, B. F., Pehmoller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Hojlund, K., 2009, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. E-pub ahead of print

    Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

    Espino Gonzalez, Ever, Dalbram, E., Mounier, R., Gondin, J., Farup, J., Jessen, N. & Treebak, Jonas Thue, 7 Mar 2024, (E-pub ahead of print) In: Cell Metabolism.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism

    Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, Agace, W., Sina, C., Kleiveland, C. R., Kristiansen, Karsten & Lea, T. E., 2021, In: Nature Communications. 12, 19 p., 1093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice

    Pendergrast, L. A., Ashcroft, Stephen Paul, Ehrlich, Amy M, Treebak, Jonas Thue, Krook, A., Dollet, L. & Zierath, Juleen R, 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    MicroRNAs in non-alcoholic fatty liver disease: Progress and perspectives

    Hochreuter, Mette Yde, Dall, M., Treebak, Jonas Thue & Barrès, Romain, 2022, In: Molecular Metabolism. 65, 17 p., 101581.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

    Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

    Kilpeläinen, T. O., Bentley, A. R., Noordam, R., Sung, Y. J., Schwander, K., Winkler, T. W., Jakupović, H., Chasman, D. I., Manning, A., Ntalla, I., Aschard, H., Brown, M. R., de las Fuentes, L., Franceschini, N., Guo, X., Vojinovic, D., Aslibekyan, S., Feitosa, M. F., Kho, M., Musani, S. K. & 32 others, Richard, M., Wang, H., Wang, Z., Bartz, T. M., Bielak, L. F., Campbell, A., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Li, C., Lohman, K. K., Marten, J., Sim, X., Smith, A. V., Tajuddin, S. M., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Evangelou, E., Gao, C., Graff, M., Harris, S. E., He, M., Hsu, F. C., Zhao, J. H., Loos, Ruth, LifeLines Cohort Study, L. C. S. & V Varga, Tibor, 2019, In: Nature Communications. 10, 11 p., 376.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    NAD+ and NAFLD - Caution, Causality, and Careful Optimism

    Dall, M., Hassing, Anna Skab & Treebak, Jonas Thue, 2022, In: The Journal of Physiology. 600, 5, p. 1135-1154

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

    Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debateResearch

  20. Published

    Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men

    Dollerup, O. L., Chubanava, Sabina, Agerholm, M., Søndergård, S. D., Altıntaş, Ali, Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde-Jørgensen, H., Lavery, G. G., Barrès, Romain, Larsen, Steen, Prats Gavalda, Clara, Jessen, N. & Treebak, Jonas Thue, 2020, In: Journal of Physiology. 598, 4, p. 731-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

    Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model

    Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, Jonas Thue, Björkqvist, M., Silahtaroglu, Asli, Hasholt, Lis Frydenreich & Nørremølle, Anne, 2018, In: Molecular and Cellular Neuroscience. 88, p. 118-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Possible role of AS160 in post-exercise increased insulin sensitivity in human skeletal muscle

    Treebak, Jonas Thue, Kristensen, Jonas Møller, Frosig, C., Pehmoller, C., Hardie, D. G., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation

    Yonamine, Caio Yogi, Passarelli, M., Suemoto, C. K., Pasqualucci, C. A., Jacob-Filho, W., Alves, V. A. F., Marie, S. K. N., Correa-Giannella, M. L., Britto, L. R. & Machado, U. F., 2023, In: Cells. 12, 9, 21 p., 1250.

    Research output: Contribution to journalJournal articleResearchpeer-review