CBMR publications and media appearances in November & December 2021
Every month we release a full list of publications from the Center, as well as media appearances by the Center scientists
Media appearances
Professor Juleen R Zierath
Dagens Medicin, 9/12/2021
‘Type-2-Diabetes: Kommunikation mellem døgnrytme og mitokondrier er i udu’
Professor Oluf Borbye Pedersen
Dagens Medicin, 10/12/2021
’Lægemidler påvirker vores tarmbakterier og dermed også vores helbred forskelligt’
Propatienter, 9/12/2021
’Nogle lægemidler kan påvirke vores tarmbakterier positivt’ (no longer available online)
Information.dk, 27/11/2021
'Professor: Tarmbakterier påvirker vores psyke og sundhed på måder, vi kun langsomt er ved at forstå'
Information.dk, 27/11/2021, for subscribers only, page 20
’Universet i vores indre’
Naturli.dk, 16/11/2021
'Gaven til maven – spis dig til bedre fordøjelse med glutenfri mad'
Videnskab.dk, 11/11/2021
'Skyldes sammenhæng mellem autisme og tarmbakterier blot kræsne kostvaner?'
Magasinet Sundhed, 7/11/2021
’Tarmbakterier påvirker udfaldet ved kræftbehandling’
Diabetes.dk, 5/11/2021
'Dine tarme er en hjælpsom kemifabrik'
Professor Romain Barrès
Aktuel Naturvidenskab, 20/12/2021
’Hvordan små metylgrupper kan påvirke vores aldring’
Associate Professor Tune Pers
Djøf’s Forskerforum, 11/11/2021
'Videnskabernes Selskab uddeler Lars Arge-mindepriser'
Publications
Arumugam Group
Mirzayi C, et al. Reporting guidelines for human microbiome research: the STORMS checklist. Nat Med. 2021 Nov;27(11):1885-1892. doi: 10.1038/s41591-021-01552-x. Epub 2021 Nov 17.
Bäckhed Group
Arora T & Tremaroli V. Therapeutic Potential of Butyrate for Treatment of Type 2 Diabetes. Front Endocrinol (Lausanne). 2021 Oct 19;12:761834. doi: 10.3389/fendo.2021.761834.
Hinrichsen F, et al. Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis. Cell Metab. 2021 Dec 7;33(12):2355-2366.e8. doi: 10.1016/j.cmet.2021.11.004. Epub 2021 Nov 29.
Bäckhed, Hansen & Pedersen Groups
Forslund SK, et al. Combinatorial, additive and dose-dependent drug-microbiome associations. Nature. 2021 Dec;600(7889):500-505. doi: 10.1038/s41586-021-04177-9. Epub 2021 Dec 8.
Barrès Group
Moreno-Asso A, et al. Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome. J Mol Endocrinol. 2021 Nov 1:JME-21-0212.R1. doi: 10.1530/JME-21-0212. Epub ahead of print.
Wohlwend M, et al. The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging. Sci Transl Med. 2021 Dec 8;13(623):eabc7367. doi: 10.1126/scitranslmed.abc7367. Epub 2021 Dec 8.
Barrès & Emanuelli Groups
Isidor MS, et al. Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes. Int J Obes (Lond). 2021 Nov 19. doi: 10.1038/s41366-021-01021-y. Epub ahead of print.
Barrès, Gillum & Treebak Groups
Dall M, et al. Hepatocyte-specific perturbation of NAD<sup>+</sup> biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. J Biol Chem. 2021 Nov 8:101388. doi: 10.1016/j.jbc.2021.101388. Epub ahead of print.
Clemmensen Group
Bavo F, et al. Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based γ-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect. J Med Chem. 2021 Dec 15. doi: 10.1021/acs.jmedchem.1c00290. Epub ahead of print.
Klein AB, et al. GDF15 in Appetite and Exercise: Essential Player or Coincidental Bystander? Endocrinology. 2022 Jan 1;163(1):bqab242. doi: 10.1210/endocr/bqab242.
Gerhart-Hines Group
Finger F, et al. The Argonaute Proteins ALG-1 and ALG-2 Are Linked to Stress Resistance and Proteostasis. MicroPubl Biol. 2021 Oct 14;2021:10.17912/micropub.biology.000457. doi: 10.17912/micropub.biology.000457.
Gerhart-Hines & Schéele Groups
Søberg S, et al. Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men. Cell Rep Med. 2021 Oct 11;2(10):100408. doi: 10.1016/j.xcrm.2021.100408.
Gillum Group
Nielsen MS, et al. Does FGF21 Mediate the Potential Decrease in Sweet Food Intake and Preference Following Bariatric Surgery? Nutrients. 2021 Oct 28;13(11):3840. doi: 10.3390/nu13113840.
Gillum, Grarup, Hansen, Moritz & Pedersen Groups
Andersen MK, et al. Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts. Gastroenterology. 2021 Dec 13:S0016-5085(21)04065-8. doi: 10.1053/j.gastro.2021.12.236. Epub ahead of print.
Grarup Group
Kizilkaya HS, et al. Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes. Front Cell Dev Biol. 2021 Oct 25;9:749607. doi: 10.3389/fcell.2021.749607.
Thambawita V, et al. DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine. Sci Rep. 2021 Nov 9;11(1):21896. doi: 10.1038/s41598-021-01295-2.
Grarup, Hansen & Pedersen Groups
Graham SE, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. 2021 Dec 9. doi: 10.1038/s41586-021-04064-3. Epub ahead of print.
Hansen Group
Jørsboe E & Albrechtsen A. Efficient approaches for large-scale GWAS with genotype uncertainty. G3 (Bethesda). 2021 Dec 4:jkab385. doi: 10.1093/g3journal/jkab385. Epub ahead of print.
-Thomsen U, et al. Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents. J Pediatr. 2021 Nov 10:S0022-3476(21)01079-9. doi: 10.1016/j.jpeds.2021.11.014. Epub ahead of print.
Torp N, et al. Binge drinking induces an acute burst of markers of hepatic fibrogenesis (PRO-C3). Liver Int. 2021 Nov 30. doi: 10.1111/liv.15120. Epub ahead of print.
Juul Holst Group
Andersen DB & Holst JJ. Peptides in the regulation of glucagon secretion. Peptides. 2021 Nov 5;148:170683. doi: 10.1016/j.peptides.2021.170683. Epub ahead of print.
Gadgaard S, et al. Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology. Br J Pharmacol. 2021 Dec 2. doi: 10.1111/bph.15766. Epub ahead of print.
van der Velden WJC, et al. Molecular and in vivo phenotyping of missense variants of the human glucagon receptor. J Biol Chem. 2021 Nov 18:101413. doi: 10.1016/j.jbc.2021.101413. Epub ahead of print.
Kilpeläinen Group
Sun D, et al. Multi-Ancestry Genome-wide Association Study Accounting for Gene- Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits. HGG Adv. 2021 Jan 14;2(1):100013. doi: 10.1016/j.xhgg.2020.100013. Epub 2020 Oct 31.
Medical Museion: Metabolic Science in Culture
Formosinho J, et al. Environmentality in biomedicine: microbiome research and the perspectival body. Stud Hist Philos Sci. 2021 Dec 15;91:148-158. doi: 10.1016/j.shpsa.2021.11.005. Epub ahead of print.
Moritz Group
Marabita F, et al. Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health. Cell Syst. 2021 Nov 30:S2405-4712(21)00451-8. doi: 10.1016/j.cels.2021.11.001. Epub ahead of print.
Pedersen Group
O'Connor MJ, et al. Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes. Diabetes. 2021 Dec 3:db210545. doi: 10.2337/db21-0545. Epub ahead of print.
Schéele Group
Grønning AGB, et al. MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities. Biol Methods Protoc. 2021 Nov 23;6(1):bpab021. doi: 10.1093/biomethods/bpab021.
Scheele C. Perspectives on the role of brown adipose tissue in human body temperature and metabolism. Cell Rep Med. 2021 Oct 19;2(10):100427. doi: 10.1016/j.xcrm.2021.100427.
Schwartz Group
Perry-Hauser NA, et al. Assays for detecting arrestin interaction with GPCRs. Methods Cell Biol. 2021;166:43-65. doi: 10.1016/bs.mcb.2021.06.007. Epub 2021 Jul 17.
Treebak Group
Wang H, et al. Exercise Effects on γ3-AMPK Activity, Akt Substrate of 160 kDa Phosphorylation, and Glucose Uptake in Muscle of Normal and Insulin Resistant Female Rats. J Appl Physiol (1985). 2021 Dec 9. doi: 10.1152/japplphysiol.00533.2021. Epub ahead of print.
Zierath Group
Stocks B & Zierath JR. Post-translational modifications: The signals at the intersection of exercise, glucose uptake and insulin sensitivity. Endocr Rev. 2021 Nov 3:bnab038. doi: 10.1210/endrev/bnab038. Epub ahead of print.