CBMR publications and media appearances in June and July 2022
Every month we release a full list of publications from the Center, as well as media appearances by the Center scientists
Media appearances
Professor Thorkild I.A. Sørensen
Sundhedspolitisk Tidsskrift, 17/06/22
'Nysgerrig podcastserie om vacciner borer i politisk ukorrekte varme kartofler'
Publications
Arumugam Group
Christensen ED, et al. The developing airway and gut microbiota in early life is influenced by age of older siblings. Microbiome. 2022 Jul 13;10(1):106. doi: 10.1186/s40168-022-01305-z.
Bäckhed Group
Fluitman KS, et al. Gut microbial characteristics in poor appetite and undernutrition: a cohort of older adults and microbiota transfer in germ-free mice. J Cachexia Sarcopenia Muscle. 2022 Jun 14. doi: 10.1002/jcsm.13002. Epub ahead of print.
Meijnikman AS, et al. Hyperinsulinemia is Highly Associated with Markers of Hepatocytic Senescence in Two Independent Cohorts. Diabetes. 2022 Jun 17:db211076. doi: 10.2337/db21-1076. Epub ahead of print.
Bäckhed & Gerhart-Hines Groups
Makki K, et al. 6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice. Gut. 2022 Jun 13:gutjnl-2021-326541. doi: 10.1136/gutjnl-2021-326541. Epub ahead of print.
Barrès Group
Manitta E, et al. DNA Methylation and Gene Expression in Blood and Adipose Tissue of Adult Offspring of Women with Diabetes in Pregnancy-A Validation Study of DNA Methylation Changes Identified in Adolescent Offspring. Biomedicines. 2022 May 26;10(6):1244. doi: 10.3390/biomedicines10061244.
McIlvenna LC, et al. Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome. J Physiol. 2022 Jul;600(14):3313-3330. doi: 10.1113/JP282954. Epub 2022 Jun 27.
Clemmensen Group
Nordgaard C, et al. ZAKβ is activated by cellular compression and mediates contraction- induced MAP kinase signaling in skeletal muscle. EMBO J. 2022 Jul 28:e111650. doi: 10.15252/embj.2022111650. Epub ahead of print.
Deshmukh Group
Gonzalez-Franquesa A, et al. Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. Redox Biol. 2022 Aug;54:102353. doi: 10.1016/j.redox.2022.102353. Epub 2022 Jun 24.
Deshmukh & Zierath Groups
Savikj M, et al. Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial. Metabolism. 2022 Jul 28;135:155268. doi: 10.1016/j.metabol.2022.155268. Epub ahead of print.
Gerhart-Hines Group
Markussen LK, et al. Lipolysis regulates major transcriptional programs in brown adipocytes. Nat Commun. 2022 Jul 8;13(1):3956. doi: 10.1038/s41467-022-31525-8.
Gillum & Juul Holst Groups
Hellmann PH, et al. The effect of curcumin on hepatic fat content in individuals with obesity. Diabetes Obes Metab. 2022 Jul 1. doi: 10.1111/dom.14804. Epub ahead of print.
Hansen Group
Bjerregaard P, et al. The Greenland population health survey 2018 - methods of a prospective study of risk factors for lifestyle related diseases and social determinants of health amongst Inuit. Int J Circumpolar Health. 2022 Dec;81(1):2090067. doi: 10.1080/22423982.2022.2090067.
Johansen MJ, et al. Possible prediction of obesity-related liver disease in children and adolescents using indices of body composition. Pediatr Obes. 2022 Jun 21:e12947. doi: 10.1111/ijpo.12947. Epub ahead of print.
Johansen S, et al. External validation of a genetic risk score that predicts development of alcohol-related cirrhosis. J Hepatol. 2022 Jun 13:S0168-8278(22)00365-8. doi: 10.1016/j.jhep.2022.06.006. Epub ahead of print.
Niu L, et al. Noninvasive proteomic biomarkers for alcohol-related liver disease. Nat Med. 2022 Jun;28(6):1277-1287. doi: 10.1038/s41591-022-01850-y. Epub 2022 Jun 2.
Shah AA, et al. Molecular Insights into the Role of Pathogenic nsSNPs in GRIN2B Gene Provoking Neurodevelopmental Disorders. Genes (Basel). 2022 Jul 26;13(8):1332. doi: 10.3390/genes13081332.
Silventoinen K, et al. Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts. Sci Rep. 2022 Jul 31;12(1):13148. doi: 10.1038/s41598-022-17536-x.
Solomon O, et al. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108415. doi: 10.1016/j.mrrev.2022.108415. Epub 2022 Mar 14.
Rydén M, et al. Lipolysis defect in people with obesity who undergo metabolic surgery. J Intern Med. 2022 Jun 7. doi: 10.1111/joim.13527. Epub ahead of print.
Juul Holst Group
Andreasen CR, et al. Hypoglycaemia and rebound hyperglycaemia increase left ventricular systolic function in patients with type 1 diabetes. Diabetes Obes Metab. 2022 Jun 7. doi: 10.1111/dom.14790. Epub ahead of print.
Boer GA, et al. Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice. Br J Pharmacol. 2022 Jun 16. doi: 10.1111/bph.15894. Epub ahead of print.
Jensen NJ, et al. Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial. Clin Nutr. 2022 Jul;41(7):1605-1612. doi: 10.1016/j.clnu.2022.05.005. Epub 2022 May 18.
Lindquist P, et al. The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection. Front Endocrinol (Lausanne). 2022 Jun 29;13:891586. doi: 10.3389/fendo.2022.891586.
Maruszczak K, et al. Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice. Am J Physiol Endocrinol Metab. 2022 Jul 13. doi: 10.1152/ajpendo.00122.2022. Epub ahead of print.
Richter MM, et al. The Liver-Alpha Cell Axis in Health and in Disease. Diabetes. 2022 Jun 3:dbi220004. doi: 10.2337/dbi22-0004. Epub ahead of print.
Schmidt LH, et al. Segmental reversal of the distal small intestine in a short bowel syndrome model in piglets showed detrimental effect on weight gain. BMC Gastroenterol. 2022 Jul 20;22(1):349. doi: 10.1186/s12876-022-02418-3.
Shah A, et al. Glucagon-like peptide-1 effect on β-cell function varies according to diabetes remission status after Roux-en-Y gastric bypass. Diabetes Obes Metab. 2022 Jun 8. doi: 10.1111/dom.14793. Epub ahead of print.
Stensen S, et al. Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in Beta Cell Function in Patients with Type 2 Diabetes. Diabetes. 2022 Jul 7:db220059. doi: 10.2337/db22-0059. Epub ahead of print.
Wewer Albrechtsen NJ, et al. Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes. Diabetes Obes Metab. 2022 Jun 8. doi: 10.1111/dom.14789. Epub ahead of print.
Loos Group
Abdulkadir M, et al. The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study. Am J Hum Genet. 2022 Jul 7;109(7):1242-1254. doi: 10.1016/j.ajhg.2022.05.005. Epub 2022 Jun 14.
Hall KD, et al. Reply to G Taubes, MI Friedman, and V Torres-Carot et al. Am J Clin Nutr. 2022 Aug 4;116(2):614-616. doi: 10.1093/ajcn/nqac163.
Winkler TW, et al. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Commun Biol. 2022 Jun 13;5(1):580. doi: 10.1038/s42003-022-03448-z.
Pers Group
Cheng W, et al. Hindbrain circuits in the control of eating behaviour and energy balance. Nat Metab. 2022Jul;4(7):826-835. doi: 10.1038/s42255-022-00606-9. Epub 2022 Jul 25.
Sakamoto Group
Marr L, et al. Mechanism of glycogen synthase inactivation and interaction with glycogenin. Nat Commun. 2022 Jun 11;13(1):3372. doi: 10.1038/s41467-022-31109-6.
Schéele Group
Hayashi Y, et al. Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity. iScience. 2022 Jun 7;25(7):104547. doi: 10.1016/j.isci.2022.104547.
Schwartz Group
Mamedova E, et al. Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons. Neuropeptides. 2022 Aug;94:102261. doi: 10.1016/j.npep.2022.102261. Epub 2022 Jun 3.
Xu R, et al. A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers. Sci Transl Med. 2022 Jul 20;14(654):eabf1922. doi: 10.1126/scitranslmed.abf1922. Epub 2022 Jul 20.
Treebak Group
Damgaard MV & Treebak JT. Protocol for qPCR analysis that corrects for cDNA amplification efficiency. STAR Protoc. 2022 Jul 11;3(3):101515. doi: 10.1016/j.xpro.2022.101515. Epub ahead of print.
Ferraz-Bannitz R, et al. Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial. Nutrients. 2022 Jun 28;14(13):2670. doi: 10.3390/nu14132670.