1. juni 2023

CBMR publications and media appearances in April & May 2023

Media & Publications

Every month we release a full list of publications from the Center, as well as media appearances by the Center scientists

CBMR media and publications logo

Media Appearances

Center for Basic Metabolic Research (CBMR)

Berlingske, 25/04/2023 (Section 2 (Business), page 6-7)
'Navneskift skal skabe investorinteresse for kræftselskab'

Ritzau, 25/04/2023
'Massiv forskningsbevilling skal imødegå voksende global folkesundhedskrise'

Science Report, 26/04/2023
'Milliardbevilling til forskningscenter åbner for nye mål og talentrekruttering'


Professor Ruth Loos

Altinget Sundhed, 03/05/2023
'Novo Nordisk Fondens pris for fedmeforskning går til KU professor'


Associate Professor Christoffer Clemmensen

Ritzau, 24/04/2023
'Rygetrangen kan måske dæmpes med kendt medicin'

Dagens Pharma, 22/05/2023
'Kombi af nikotin og vægttabsmedicin kan have interessant effekt på rygetrang og vægt'


Curator Aslak Aamot Helm

Kunsten.nu, 02/05/2023
'Vi åbner samtaler om kunst uden for den komfortzone, som kunsten normalt bevæger sig i'



Arumugam Group
Shah SA, et al. Expanding known viral diversity in the healthy infant gut. Nat Microbiol. 2023 May;8(5):986-998. doi: 10.1038/s41564-023-01345-7. Epub 2023 Apr 10.


Arumugam, Clemmensen & Schwartz Groups
Gradel AKJ, et al. The dietary regulation of LEAP2 depends on meal composition in mice. FASEB J. 2023 Jun;37(6):e22923. doi: 10.1096/fj.202201828R.


Arumugam, Gerhart-Hines & Treebak Groups
Peluso AA, et al. Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans. NPJ Aging. 2023 Apr 3;9(1):7. doi: 10.1038/s41514-023-00106-4.


Barrès Group
Crean AJ, et al. Male reproductive traits are differentially affected by dietary macronutrient balance but unrelated to adiposity. Nat Commun. 2023 May 4;14(1):2566. doi: 10.1038/s41467-023-38314-x.

Voisin S, et al. Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle. Aging Cell. 2023 May 2:e13859. doi: 10.1111/acel.13859. Epub ahead of print.


Clemmensen Group
Griem-Krey N, et al. The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα. J Cereb Blood Flow Metab. 2023 Apr 7:271678X231167920. doi: 10.1177/0271678X231167920. Epub ahead of print.

Ranea-Robles P & Houten SM. The biochemistry and physiology of long-chain dicarboxylic acid metabolism. Biochem J. 2023 May 15;480(9):607-627. doi: 10.1042/BCJ20230041.


Clemmensen, Emanuelli & Gerhart-Hines Groups
Lund J, et al. The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions. Nat Metab. 2023 Apr;5(4):677-698. doi: 10.1038/s42255-023-00780-4. Epub 2023 Apr 13.


Clemmensen & Pers Groups
Falk S, et al. GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity. Cell Rep. 2023 May 2:112466. doi: 10.1016/j.celrep.2023.112466. Epub ahead of print.


Gerhart-Hines Group
Bager Christensen I, et al. Effect of simvastatin treatment on mitochondrial function and inflammatory status of human white adipose tissue. J Clin Endocrinol Metab. 2023 May 10:dgad259. doi: 10.1210/clinem/dgad259. Epub ahead of print.


Gerhart-Hines & Treebak Groups
Backe MB, et al. PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity. J Endocr Soc. 2023 May 16;7(6):bvad057. doi: 10.1210/jendso/bvad057.


Grarup & Hansen Groups
Huang Y, et al. An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents. Liver Int. 2023 May 20. doi: 10.1111/liv.15613. Epub ahead of print.

Thuesen ACB, et al. Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment. Mol Genet Metab Rep. 2023 Mar 29;35:100972. doi: 10.1016/j.ymgmr.2023.100972.


Grarup, Hansen & Juul Holst Groups
Melchiorsen JU, et al. Rare heterozygous loss-of-function variants in the human GLP-1 receptor do not associate with cardiometabolic phenotypes. J Clin Endocrinol Metab. 2023 May 26:dgad290. doi: 10.1210/clinem/dgad290. Epub ahead of print.


Guasch Group
Alasalvar C, et al. Dried Fruits: Bioactives, Effects on Gut Microbiota, and Possible Health Benefits-An Update. Nutrients. 2023 Mar 26;15(7):1611. doi: 10.3390/nu15071611.


Hansen Group
Elingaard-Larsen LO, et al. Circulating Metabolomic and Lipidomic Signatures Identify a Type 2 Diabetes Risk Profile in Low-Birth-Weight Men with Non-Alcoholic Fatty Liver Disease. Nutrients. 2023 Mar 24;15(7):1590. doi: 10.3390/nu15071590.

Gersing S, et al. A comprehensive map of human glucokinase variant activity. Genome Biol. 2023 Apr 26;24(1):97. doi: 10.1186/s13059-023-02935-8.

Gul R, et al. Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing. Front Genet. 2023 Apr 5;14:1128850. doi: 10.3389/fgene.2023.1128850.

Hajra B, et al. A novel homozygous nonsense mutation in NECTIN4 gene in a Pakistani family with ectodermal dysplasia syndactyly syndrome 1. An Bras Dermatol. 2023 May 12:S0365-0596(23)00085-5. doi: 10.1016/j.abd.2022.07.009. Epub ahead of print.

Lewis JI, et al. The effect of traditional diet on glucose homoeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: a randomised crossover study. Br J Nutr. 2023 May 2:1-14. doi: 10.1017/S000711452300106X. Epub ahead of print.


Juul Holst Group
Legaard GE, et al. Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial. Nat Metab. 2023 May;5(5):880-895. doi: 10.1038/s42255-023-00799-7. Epub 2023 May 1.

Ludwig DS & Holst JJ. Childhood Obesity at the Crossroads of Science and Social Justice. JAMA. 2023 May 1. doi: 10.1001/jama.2023.7592. Epub ahead of print.

Madsbad S, et al. Does glucose lowering restore GIP's effect on insulin secretion? Nutr Metab Cardiovasc Dis. 2023 Apr 15:S0939-4753(23)00141-2. doi: 10.1016/j.numecd.2023.03.022. Epub ahead of print.


Kilpeläinen Group
Burrinha T, et al. Deacidification of endolysosomes by neuronal aging drives synapse loss. Traffic. 2023 May 23. doi: 10.1111/tra.12889. Epub ahead of print.

Drag MH, et al. Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs. Epigenetics. 2023 Dec;18(1):2199374. doi: 10.1080/15592294.2023.2199374.

Toh PJY, et al. Optogenetic control of YAP can enhance the rate of wound healing. Cell Mol Biol Lett. 2023 May 11;28(1):39. doi: 10.1186/s11658-023-00446-9.


Loos Group
Huerta-Chagoya A, et al. The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. Diabetologia. 2023 May 6. doi: 10.1007/s00125-023-05912-9. Epub ahead of print.

Johansson Å, et al. Precision medicine in complex diseases- Molecular subgrouping for improved prediction and treatment stratification. J Intern Med. 2023 Apr 24. doi: 10.1111/joim.13640. Epub ahead of print.


Medical Museion
Hussey KD. Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938-1963. Hist Philos Life Sci. 2023 Apr 19;45(2):17. doi: 10.1007/s40656-023-00571-w.

Pradeu T, et al. Reuniting philosophy and science to advance cancer research. Biol Rev Camb Philos Soc. 2023 May 8. doi: 10.1111/brv.12971. Epub ahead of print.


Merino Group
Merino J, et al. Genetic predisposition to macronutrient preference and workplace food choices. Mol Psychiatry. 2023 May 23. doi: 10.1038/s41380-023-02107-x. Epub ahead of print.


Moritz Group
Donati S, et al. An automated workflow for multi-omics screening of microbial model organisms. NPJ Syst Biol Appl. 2023 May 19;9(1):14. doi: 10.1038/s41540-023-00277-6.

Hodek O, et al. Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 May 1;1222:123719. doi: 10.1016/j.jchromb.2023.123719. Epub 2023 Apr 11.


Rodent Metabolic Phenotyping Platform
Dall M & Pedersen MH. Denmark's big tent includes postdocs. Science. 2023 Apr 14;380(6641):143. doi: 10.1126/science.adh4261. Epub 2023 Apr 13.


Schwartz Group
Tough IR, et al. Paracrine relationship between incretin hormones and endogenous 5-hydroxytryptamine in the small and large intestine. Neurogastroenterol Motil. 2023 Apr 3:e14589. doi: 10.1111/nmo.14589. Epub ahead of print.


Treebak Group
Kjøbsted R, et al. TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction. Diabetes. 2023 Apr 19:db220666. doi: 10.2337/db22-0666. Epub ahead of print.

Yonamine CY, et al. Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation. Cells. 2023 Apr 25;12(9):1250. doi: 10.3390/cells12091250.


Pers Group
Lee J, et al. A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development. Sci Adv. 2023 Apr 7;9(14):eadd5745. doi: 10.1126/sciadv.add5745. Epub 2023 Apr 7.


Sakamoto Group
Lopez-Escalera S, et al. In Vitro Screening for Probiotic Properties of Lactobacillus and Bifidobacterium Strains in Assays Relevant for Non-Alcoholic Fatty Liver Disease Prevention. Nutrients. 2023 May 18;15(10):2361. doi: 10.3390/nu15102361.


Zierath Group
Smith JAB, et al. Exercise metabolism and adaptation in skeletal muscle. Nat Rev Mol Cell Biol. 2023 May 24. doi: 10.1038/s41580-023-00606-x. Epub ahead of print.