Clemmensen Group

  1. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

    Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans

    Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice

    Jall, S., Finan, B., Collden, G., Fischer, K., Dong, X., Tschoep, M. H., Mueller, T. D. & Clemmensen, Christoffer, 2019, In: Molecular Metabolism. 23, p. 75-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity

    Jall, S., De Angelis, M., Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Klein, A. B., Novikoff, A., Sachs, S., Richter, Erik A., Kiens, Bente, Schramm, K., Tschöp, M. H., Stemmer, K., Clemmensen, Christoffer, Müller, T. D. & Kleinert, Maximilian, 2020, In: Diabetologia. 63, 6, p. 1236-1247 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Overlooked confounding in studies of metabolite salts

    Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.

    Research output: Contribution to journalComment/debateResearch

  10. Published

    Outrunning obesity with Lac-Phe?

    Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  11. Published
  12. Published

    Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases

    Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  13. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debateResearch

  14. Published

    Muscarinic receptors in energy homeostasis: Physiology and pharmacology

    Falk, S., Lund, Camilla & Clemmensen, Christoffer, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Suppl. 6, p. 66-76 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

    Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Linking Hypothermia and Altered Metabolism with TrkB Activation

    Alitalo, O., González-Hernández, G., Rosenholm, Marko, Kohtala, P., Matsui, N., Müller, H. K., Theilmann, W., Klein, A., Kärkkäinen, O., Rozov, S., Rantamäki, T. & Kohtala, S., 2023, In: ACS Chemical Neuroscience. 14, 17, p. 3212–3225

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    LEAP2 is associated with cardiometabolic markers but is unchanged by antidiabetic treatment in people with prediabetes

    Byberg, Sarah, Blond, Martin Bæk, Holm, Stephanie Kjærulff, Amadid, H., Nielsen, L. B., Clemmensen, K. K. B., Færch, K. & Holst, Birgitte, 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 3, p. E244-E251

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Ketone monoester increases circulating levels of LEAP2 and decreases appetite in healthy men

    Holm, Stephanie Kjærulff, Vestergaard, E. T., Zubanovic, N. B., Byberg, Sarah, Clemmensen, Christoffer, Holst, Birgitte & Thomsen, H. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 7, p. :2023–2027

    Research output: Contribution to journalLetterResearchpeer-review

  22. Published
  23. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journalComment/debateResearch

  24. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling

    Alexopoulou, Flora, Buch-Månson, N., Pedersen, S. L., Vrang, N., Fink, L. N. & Strømgaard, Kristian, 2023, In: Peptides. 168, 7 p., 171063.

    Research output: Contribution to journalJournal articleResearchpeer-review