- 2024
- Published
An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity
Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atlas of exercise-induced brain activation in mice
Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1-directed NMDA receptor antagonism for obesity treatment
Petersen, J., Ludwig, M. Q., Juozaityte, V., Ranea-Robles, P., Svendsen, C., Hwang, E., Kristensen, A. W., Fadahunsi, N., Lund, J., Breum, A. W., Mathiesen, C. V., Sachs, L., Moreno-Justicia, R., Rohlfs, R., Ford, J. C., Douros, J. D., Finan, B., Portillo, B., Grose, K., Petersen, J. E. & 13 others, , 2024, In: Nature. 629, 8014, p. 1133–1141Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
ADA/EASD PMDI, A. P., Merino, Jordi, Thuesen, Anne Cathrine Baun, Lepola, Mette Andersen, Clemmensen, Christoffer, Hansen, Torben, Nakabuye, Mariam, Loos, Ruth, Guasch Ferre, Marta & Vilsbøll, Tina, 2024, In: Communications Medicine. 4, 1, 8 p., 66.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Cross-species comparison of pregnancy-induced GDF15
Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice
Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do psychedelics have therapeutic potential for obesity?
Fadahunsi, N., Knudsen, Gitte Moos & Clemmensen, Christoffer, 2023, In: Nature Reviews Endocrinology. 19, p. 1-2Research output: Contribution to journal › Comment/debate › Research
- Published
Effects of acute exercise and exercise training on plasma GDF15 concentrations and associations with appetite and cardiometabolic health in individuals with overweight or obesity – A secondary analysis of a randomized controlled trial
Quist, Jonas Salling, Klein, A. B., Færch, K., Beaulieu, K., Rosenkilde, M., Gram, A. S., Sjödin, Anders Mikael, Torekov, Signe Sørensen, Stallknecht, Bente Merete, Clemmensen, Christoffer & Blond, Martin Bæk, 2023, In: Appetite. 182, 11 p., 106423.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism
Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity
Falk, S., Petersen, Jonas Odgaard, Svendsen, C. S. A., Leguizamon, Cesar Ramon Romero, Jørgensen, Søren Heide, Krauth, Nathalie, Ludwig, M. Q., Jørgensen, Kathrine Lundø, Roostalu, U., Hjort-Gregersen, G. S., Nielsen, D. A. G., Ejdrup, Aske Lykke, Pers, Tune H, Dmytriyeva, O., Hecksher-Soerensen, J., Gether, Ulrik, Kohlmeier, Kristi Anne & Clemmensen, Christoffer, 2023, In: Cell Reports. 42, 5, 18 p., 112466.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling
Alexopoulou, Flora, Buch-Månson, N., Pedersen, S. L., Vrang, N., Fink, L. N. & Strømgaard, Kristian, 2023, In: Peptides. 168, 7 p., 171063.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review
Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is lactate a driver of skin burn-induced adipose browning?
Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Ketone monoester increases circulating levels of LEAP2 and decreases appetite in healthy men
Holm, Stephanie Kjærulff, Vestergaard, E. T., Zubanovic, N. B., Byberg, Sarah, Clemmensen, Christoffer, Holst, Birgitte & Thomsen, H. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 7, p. :2023–2027Research output: Contribution to journal › Letter › Research › peer-review
- Published
LEAP2 is associated with cardiometabolic markers but is unchanged by antidiabetic treatment in people with prediabetes
Byberg, Sarah, Blond, Martin Bæk, Holm, Stephanie Kjærulff, Amadid, H., Nielsen, L. B., Clemmensen, K. K. B., Færch, K. & Holst, Birgitte, 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 3, p. E244-E251Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linking Hypothermia and Altered Metabolism with TrkB Activation
Alitalo, O., González-Hernández, G., Rosenholm, Marko, Kohtala, P., Matsui, N., Müller, H. K., Theilmann, W., Klein, A., Kärkkäinen, O., Rozov, S., Rantamäki, T. & Kohtala, S., 2023, In: ACS Chemical Neuroscience. 14, 17, p. 3212–3225Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overlooked confounding in studies of metabolite salts
Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Physiological protection against weight gain: evidence from overfeeding studies and future directions
Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.Research output: Contribution to journal › Review › Research › peer-review
- Published
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review
Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.Research output: Working paper › Preprint › Research
- Published
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, , 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα
Griem-Krey, Nane, Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., Nagaraja, R. Y., De Silva, T. M., Sobey, C. G., Cheng, H. C., Orset, C., Vivien, D., Lambertsen, K. L., Clarkson, A. N. & Wellendorph, Petrine, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 8, p. 1419-1434Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, , 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The biochemistry and physiology of long-chain dicarboxylic acid metabolism
Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The dietary regulation of LEAP2 depends on meal composition in mice
Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging
Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice
Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2
Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice
Breum, Alberte Wollesen, Falk, S., Svendsen, C. S. A., Nicolaisen, T. S., Mathiesen, C. V., Maskos, U. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 7, 9 p., bqac079.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme duration exercise affects old and younger men differently
Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, , 2022, In: Acta Physiologica. 235, 3, e13816.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GDF15 in appetite and exercise: Essential player or coincidental bystander?
Klein, A. B., Kleinert, Maximilian, Richter, Erik A. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 1, p. 1-10 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice
Quarta, C., Stemmer, K., Novikoff, A., Yang, B., Klingelhuber, F., Harger, A., Bakhti, M., Bastidas-Ponce, A., Baugé, E., Campbell, J. E., Capozzi, M., Clemmensen, C., Collden, G., Cota, P., Douros, J., Drucker, D. J., DuBois, B., Feuchtinger, A., Garcia-Caceres, C., Grandl, G. & 20 others, , 2022, In: Nature Metabolism. 4, 8, p. 1071-1083 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells
Elmelund, E., Galsgaard, Katrine Douglas, Johansen, C. D., Trammell, Sam, Billeschou, Anna, Winther-Sørensen, Marie, Dal, Jenna Elizabeth Hunt, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Grevengoed, Trisha Jean, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: iScience. 25, 11, 20 p., 105296.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outrunning obesity with Lac-Phe?
Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance
Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology of experimental overfeeding in animals
Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.Research output: Contribution to journal › Review › Research › peer-review
- Published
ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle
Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, , 2022, In: E M B O Journal. 41, 17, 19 p., e111650.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Acute erythropoietin injection increases muscle mitochondrial respiratory capacity in young men: A double-blinded randomized crossover trial
Larsen, Steen, Søndergård, S. D., Sahl, Ronni Eg, Frandsen, J., Morville, T., Dela, Flemming & Helge, Jørn Wulff, 2021, In: Journal of Applied Physiology. 131, 4, p. 1340-1347Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity
Zizzari, P., He, R., Falk, S., Bellocchio, L., Allard, C., Clark, S., Lesté-Lasserre, T., Marsicano, G., Clemmensen, Christoffer, Perez-Tilve, D., Finan, B., Cota, D. & Quarta, C., 2021, In: Diabetes. 70, 2, p. 415-422 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of thymosin β4 as a human exerkine and growth factor
Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Borg, M. L., Kuefner, M., Kellezi, Emilie Dalbram, Nielsen, Thomas Svava, Agrawal, A., Pankratova, Stanislava, Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, Niklas Rye, Clemmensen, Christoffer, Treebak, Jonas Thue, Hostrup, Morten, Krook, A., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: American Journal of Physiology: Cell Physiology. 321, 5, p. C770-C778 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women
Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, , 2021, In: Nature Communications. 12, 9 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliability and variation in mitochondrial respiration in human adipose tissue
Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spinal astroglial cannabinoid receptors control pathological tremor
Carlsen, Eva Maria Meier, Falk, S., Skupio, U., Robin, L., Zottola, A. C. P., Marsicano, G. & Perrier, Jean-Francois Marie, 2021, In: Nature Neuroscience. 24, p. 658–666 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect
Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes
StEP COMPAC Group, S. C. G., 2021, In: British Journal of Anaesthesia. 126, 1, p. 56-66 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial
Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum and the Substantia Nigra: Implications for Early Appearance of Sleep Disorders in Parkinson’s Disease
Brito dos Santos, Altair, Skaanning, L. K., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Kristensen, M. P., Klein, A. B., Thaneshwaran, S. S., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2021, In: Journal of Parkinson's Disease. 11, 4, p. 1773-1790Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Har du let eller svært ved at tage på? Måske skyldes det kalorierne i toilettet
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 1 Oct 2020, Videnskab.dk, ForskerZonen.Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction
Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582AResearch output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Compounds for the treatment of acute brain injury
Klein, A. B., Leurs, U., Houlton, J., Clausen, Rasmus Prætorius, Frølund, Bente, Clarkson, A. & Wellendorph, Petrine, 2020, Patent No. CN111989094, 24 Nov 2020, Priority date 1 Feb 2019, Priority No. PCT/DK2019/050041Research output: Patent
- Published
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation
Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism and site of action of big dynorphin on ASIC1a
Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscarinic receptors in energy homeostasis: Physiology and pharmacology
Falk, S., Lund, Camilla & Clemmensen, Christoffer, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Suppl. 6, p. 66-76 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research
Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, , 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.Research output: Contribution to journal › Comment/debate › Research
- Published
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
Jall, S., De Angelis, M., Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Klein, A. B., Novikoff, A., Sachs, S., Richter, Erik A., Kiens, Bente, Schramm, K., Tschöp, M. H., Stemmer, K., Clemmensen, Christoffer, Müller, T. D. & Kleinert, Maximilian, 2020, In: Diabetologia. 63, 6, p. 1236-1247 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
Fischer, K., Fenzl, A., Liu, D., Dyar, K. A., Kleinert, M., Brielmeier, M., Clemmensen, C., Fedl, A., Finan, B., Gessner, A., Jastroch, M., Huang, J., Keipert, S., Klingenspor, M., Brüning, J. C., Kneilling, M., Maier, F. C., Othman, A. E., Pichler, B. J., Pramme-Steinwachs, I. & 13 others, , 2020, In: Nature Communications. 11, 1, 13 p., 2306.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The unidentified hormonal defense against weight gain
Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Will the COVID-19 pandemic worsen the obesity epidemic?
Clemmensen, Christoffer, Petersen, M. B. & Sørensen, Thorkild I.A., 2020, In: Nature Reviews Endocrinology. 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2019
- Published
The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation
Bousard, A., Raposo, A. C., Żylicz, J. J., Picard, C., Pires, V. B., Qi, Y., Gil, Cláudia, Syx, L., Chang, H. Y., Heard, E. & da Rocha, S. T., 4 Oct 2019, In: EMBO Reports. 20, 10, e48019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain
Falk, S., Appel, C. K., Bennedbæk, H. B., Al-Dihaissy, T., Unger, A., Dinkel, K. & Heegaard, Anne-Marie, 15 Feb 2019, In: European Journal of Pharmacology. 845, p. 48-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study
Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities
Petersen, Jonas Odgaard, Strømgaard, Kristian, Frølund, Bente & Clemmensen, Christoffer, 2019, In: Drugs. 79, 11, p. 1187-1197 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases
Clemmensen, Christoffer, Finan, B., Müller, T. D., DiMarchi, R. D., Tschöp, M. H. & Hofmann, S. M., 2019, In: Nature Reviews Endocrinology. 15, p. 90-104Research output: Contribution to journal › Review › Research › peer-review
- Published
GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice
Decarie-Spain, L., Fisette, A., Zhu, Z., Yang, B., DiMarchi, R. D., Tschoep, M. H., Finan, B., Fulton, S. & Clemmensen, Christoffer, 2019, In: Neuropharmacology. 151, p. 55-63Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway
Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice
Jall, S., Finan, B., Collden, G., Fischer, K., Dong, X., Tschoep, M. H., Mueller, T. D. & Clemmensen, Christoffer, 2019, In: Molecular Metabolism. 23, p. 75-81Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unge forskere: S-løftebrud er en katastrofe for universiteterne
Aguirre, V., Andersen, C., Andersen, P. R., Bjørk, R., Clemmensen, C., Dalsgaard, P., Danbolt, M., Dimke, H., Engberg-Pedersen, A., Feliu, E., Jauffred, L., Jønsson, K., Kornum, B. R., Kropp, K., Laustsen, A., Levisen, C., Lock, N., Lomborg, S., Møller, N. M., Niss, K. & 5 others, , 2019Research output: Other contribution › Communication
- 2018
- Published
Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.
Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Accelerated food source location in aging Drosophila.
Egenriether, S., Chow, E., Krauth, Nathalie & Giebultowicz, J., 23 Jun 2015, In: Aging Cell.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases
Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
Research output: Contribution to journal › Journal article › Research › peer-review
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108
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Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
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94
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Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Research output: Contribution to journal › Journal article › Research › peer-review
Published
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
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