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Outrunning obesity with Lac-Phe?
Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation
Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.Research output: Contribution to journal › Journal article › Research › peer-review
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Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study
Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.
Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases
Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle
Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, , 2022, In: E M B O Journal. 41, 17, 19 p., e111650.Research output: Contribution to journal › Journal article › Research › peer-review
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Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities
Petersen, Jonas Odgaard, Strømgaard, Kristian, Frølund, Bente & Clemmensen, Christoffer, 2019, In: Drugs. 79, 11, p. 1187-1197 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice
Quarta, C., Stemmer, K., Novikoff, A., Yang, B., Klingelhuber, F., Harger, A., Bakhti, M., Bastidas-Ponce, A., Baugé, E., Campbell, J. E., Capozzi, M., Clemmensen, C., Collden, G., Cota, P., Douros, J., Drucker, D. J., DuBois, B., Feuchtinger, A., Garcia-Caceres, C., Grandl, G. & 20 others, , 2022, In: Nature Metabolism. 4, 8, p. 1071-1083 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of acute exercise and exercise training on plasma GDF15 concentrations and associations with appetite and cardiometabolic health in individuals with overweight or obesity – A secondary analysis of a randomized controlled trial
Quist, Jonas Salling, Klein, A. B., Færch, K., Beaulieu, K., Rosenkilde, M., Gram, A. S., Sjödin, Anders Mikael, Torekov, Signe Sørensen, Stallknecht, Bente Merete, Clemmensen, Christoffer & Blond, Martin Bæk, 2023, In: Appetite. 182, 11 p., 106423.Research output: Contribution to journal › Journal article › Research › peer-review
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The biochemistry and physiology of long-chain dicarboxylic acid metabolism
Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.Research output: Contribution to journal › Review › Research › peer-review
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The physiology of experimental overfeeding in animals
Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.Research output: Contribution to journal › Review › Research › peer-review
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Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway
Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340Research output: Contribution to journal › Journal article › Research › peer-review
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Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice
Rial-Pensado, E., Canaple, L., Guyot, R., Clemmensen, Christoffer, Wiersema, J., Wu, S., Richard, S., Boelen, A., Müller, T. D., López, M., Flamant, F. & Gauthier, K., 2023, In: Endocrinology. 164, 4Research output: Contribution to journal › Journal article › Research › peer-review
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Reliability and variation in mitochondrial respiration in human adipose tissue
Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism
Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging
Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atlas of exercise-induced brain activation in mice
Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial
Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, , 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity
Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
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Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
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Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
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