Research areas

  1. Published
  2. Design and synthesis of selective serotonin receptor agonists for positron emission tomography imaging of the brain

    Hansen, M., 16 Dec 2010, København: Det Farmaceutiske Fakultet. 207 p.

    Research output: Book/ReportPh.D. thesis

  3. Published

    Design and synthesis of new 1-hydroxypyrazole-based ligands for characterizing the GABAA receptor orthosteric binding site

    Hansen, H. M., 2009, København: Det Farmaceutiske Fakultet. 156 p.

    Research output: Book/ReportPh.D. thesis

  4. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

    Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 51, p. 9685-9689

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Design and synthesis of dimeric ligands: optimization of selectivity and potency of glutamate receptor ligands

    Thorsen, B. H. K., 2009, København: Det Farmaceutiske Fakultet. 154 p.

    Research output: Book/ReportPh.D. thesis

  6. Published

    Description of aquatic ecosystem's development by eco-exergy and exergy destruction

    Jørgensen, S. E., 2007, In: Ecological Modelling. 204, 1-2, p. 22-28

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Desaturation of excess intramyocellular triacylglycerol in obesity: implications for glycemic control

    Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, Allan, 2010, In: International Journal of Obesity. 34, 3, p. 500-510 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin

    Jensen, L. B., Nielsen, Hanne Mørck & Foged, Camilla, 2008, In: Lægemiddelforskning. p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Delivery technologies for biopharmaceuticals: a critical assessment

    van de Weert, Marco, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 407-411

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  11. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration

    Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In: Biomacromolecules. 13, p. 905-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

    Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In: Epilepsy Research. 95, 1-2, p. 70-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design

    Gloriam, David E., Foord, S. M., Blaney, F. E. & Garland, S. L., 2009, In: Journal of Medicinal Chemistry. 52, 14, p. 4429-4442

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Danish pain specialists' rationales behind the choice of fentanyl transdermal patches and oral transmucosal systems-A Delphi study

    Jacobsen, Ramune, Møldrup, C. & Christrup, Lona Louring, 2009, In: Pain Medicine. 10, 8, p. 1442-1451

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Danes' awareness of and attitude towards direct-to-consumer advertising (DTC-A) of prescription drugs: A quantitative survey of 3,000 respondents

    Rehne, J. & Møldrup, C., 2008, In: Journal of Medical Marketing (Print Edition). 8, p. 31-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cytochrome P450 in action: Rationalization and prediction through In Silico modeling of CYP1A2

    Poongavanam, V., 2010, København: Det Farmaceutiske Fakultet. 176 p.

    Research output: Book/ReportPh.D. thesis

  18. Published

    Cytochrome P450 Mediated Drug Metabolism

    Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  19. Published

    Cu(II) mediates kineticallyl distinct, non-amyloidogenic aggregation of amyloid-β peptides

    Pedersen, J. T., Østergaard, Jesper, Rozlosnik, N., Gammelgaard, Bente & Heegaard, N. H. H., 2011, In: Journal of Biological Chemistry. 286, 30, p. 26952-26963

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Crystallization of polymorphic hydrate system

    Tian, F., Qu, H., Louhi-Kultanen, M. & Rantanen, Jukka, 2010, In: Journal of Pharmaceutical Sciences. 99, p. 753-763

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Crystal morphology engineering of pharmaceutical solids: Tabletting performance enhancement

    Mirza, S., Miroshnyk, I., Heinämäki, J., Antikainen, O., Rantanen, Jukka, Vuorela, P., Vuorela, H. & Yliruusi, J., 2009, In: AAPS PharmSciTech. 10, 1, p. 113-119

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Crystal engineering: effects of amide/lactam containing additives on the crystallization behaviour of nitrofurantoin monohydrate

    Munk, T. P., Baldursdóttir, S. G. & Rantanen, Jukka, 2011. 8 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  23. Published

    Cryopreservation of differentiated HL-60 cells for pyrogen testing

    Timm, M., Bartelt, S., Moesby, L. & Hansen, E. W., 2008, In: Journal of Immunological Methods. 339, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cross-sectorial communication and drug management after hospital discharge: an observational study of heart failure patients

    Ilsøe-Kristensen, S., 2010, København. 79 p.

    Research output: Book/ReportPh.D. thesis

  25. Published

    Critical factors influencing the In Vivo performance of long-acting liophilic solutions - impact on In Vitro release method design

    Larsen, Susan Weng & Larsen, C. S., 2009, In: The AAPS Journal. 11, 4, p. 762-770

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Critical evaluation of the FANTOM3 non-coding RNA transcripts

    Nordström, K. J. V., Mirza, M. A. I., Almén, M. S., Gloriam, David E., Fredriksson, R. & Schiöth, H. B., 2009, In: Genomics. 94, 3, p. 169-176

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Creating tools for ligand-based virtual screening that use the pharmacophore concept

    Askjær, S., 2008, København: Det Farmaceutiske Fakultet. 307 p.

    Research output: Book/ReportPh.D. thesis

  28. Published

    Creating knowledge about adverse drug reactions: A critical analysis of the Danish reporting system from 1968 to 2005.

    Aagaard, L., Søndergaard, B., Andersen, E., Kampmann, J. P. & Hansen, E. H., 2007, In: Social Science & Medicine. 65, p. 1296-1309

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Corticosteroid solubility and lilpid polarity control release from solid lipid nanoparticles

    Jensen, L. B., Magnusson, E., Gunnarsson, L., Vermehren, C., Nielsen, Hanne Mørck & Petersson, K., 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 53-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Controlling production process: incorporating analytical methods

    Grohganz, Holger & Rantanen, Jukka, 2008, In: Pharma focus Asia. 8, p. 82-83

    Research output: Contribution to journalJournal articleCommunication

  32. Published

    Controlled release - macromolecular prodrugs

    Larsen, C. S., Østergaard, Jesper & Larsen, Susan Weng, 2007, Prodrugs: challenges and rewards. Stella, V. J., Borchardt, R. T., Hageman, M. J., Oliyai, R., Maag, H. & Tilley, J. W. (eds.). New York: Springer, p. 379-416

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  33. Published

    Contribution of South African plants to medicinal plant biotechnology

    Makunga, N. P., Jäger, A. K. & van Staden, J., 2008, In: South African Journal of Botany. 2, p. 372

    Research output: Contribution to journalConference abstract in journalResearch

  34. Published

    Content of antidepressant hyperforin correlates with translucent glands in Hypericum perforatum L.

    Soelberg, Jens, Johansen, B. B. & Jäger, A., Aug 2010, In: Planta Medica. 76, 12, p. 1325

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    Contamination versus preservation of cosmetics: a review on legislation, usage, infections, and contact allergy

    Lundov, M. D., Moesby, L., Zachariae, Claus & Johansen, Jeanne Duus, 2009, In: Contact Dermatitis. 60, 2, p. 70-8

    Research output: Contribution to journalReviewResearch

  36. Published

    Consumers' reports of suspected adverse drug reactions volunteered to a consumer magazine

    Aagaard, L. & Hansen, E. H., 2010, In: British Journal of Clinical Pharmacology. 69, 3, p. 317-318

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Consumer reporting of adverse drug reactions: a retrospective analysis of the Danish adverse drug reaction database from 2004 to 2006

    Aagaard, L., Nielsen, L. H. & Hansen, E. H., 2009, In: Drug Safety. 32, 11, p. 1067-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Constituents in kava extracts potentially involved in hepatotoxicity: A review

    Olsen, L. R., Grillo, M. P. & Skonberg, C., 2011, In: Chemical Research in Toxicology. 24, p. 992-1002

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Conformational changes and ligand recognition of Escherichia coli D-xylose binding protein revealed

    Sooriyaarachchi, S., Ubhayasekera, W., Park, C. & Mowbray, S. L., 1 Oct 2010, In: Journal of Molecular Biology. 402, 4, p. 657-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Concise synthesis of new bridged-nicotine analogues

    Crestey, F., Hooyberghs, G. & Kristensen, Jesper Langgaard, 4 Feb 2012, In: Tetrahedron. 68, 5, p. 1417-1421

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Computeren viser vejen til et nyt potentielt lægemiddel

    Harpsøe, Kasper, Kaae, B. H., Balle, T., Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In: Lægemiddelforskning. p. 28-30

    Research output: Contribution to journalJournal articleCommunication

  42. Published

    Computeren forudsiger lægemidlers omdannelse i leveren

    Rydberg, P. & Olsen, L., Dec 2011, In: Lægemiddelforskning. 2011, p. 44-46

    Research output: Contribution to journalJournal articleCommunication

  43. Published

    Computeren er medicinalkemikerens arbejdshest

    Larsen, S. B., Olsen, L. & Jørgensen, Flemming Steen, 2009, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  44. Published

    Computational studies of the human peptide transporter (hPEPT1) and development of tools for virtual screening

    Larsen, S. B., 2010, København: Det Farmaceutiske Fakultet. 111 p.

    Research output: Book/ReportPh.D. thesis

  45. Published

    Computational studies of the glutamate binding domain of NMDA receptors

    Bjerrum, E. J., 2008, København: Det Farmaceutiske Fakultet. 196 p.

    Research output: Book/ReportPh.D. thesis

  46. Published

    Computational studies of p38 MAP kinase: molecular dynamics and GRID-based scaffold hopping

    Bergmann, R., 2009, København: Det Farmaceutiske Fakultet. 178 p.

    Research output: Book/ReportPh.D. thesis

  47. Published

    Computational prediction of solubilizers' effect on partitioning

    Høst, J., Christensen, I. T., Jørgensen, Flemming Steen, Frøkjær, Sven & Hovgaard, L., 2007, In: Internation Journal of Pharmaceutics. 329, 1-2, p. 46-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Computational prediction of binding affinity for CYP1A2-ligand complexes using empirical free energy calculations

    Poongavanam, V., Olsen, L., Jørgensen, Flemming Steen, Vermeulen, N. P. E. & Oostenbrink, C., 2010, In: Drug Metabolism and Disposition. 38, 8, p. 1347-1354

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Compressibility and compactibility of granules produced by wet and dry granulation

    Bacher, C., Olsen, P. M., Berthelsen, P. & Møller-Sonnergaard, Jørn, 2008, In: Internation Journal of Pharmaceutics. 358, 1-2, p. 69-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Compounds from Mentha aquatica with affinity to the GABA-benzodiazepine receptor

    Jäger, A. K., Almqvist, J. P., Vangsøe, S. A. K., Stafford, G. I., Adsersen, A. & van Staden, J., 2007, In: South African Journal of Botany. 73, 4, p. 518-521

    Research output: Contribution to journalJournal articleResearchpeer-review