Gerhart-Hines Group

  1. 2011
  2. Published

    The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +

    Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming

    Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2010
  5. Published

    Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5

    Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. 2009
  7. Published

    Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

    Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity

    Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

    Suchankova, G., Nelson, L. E., Gerhart-Hines, Zach, Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2008
  11. Published

    Metabolic adaptations through the PGC-1α and SIRT1 pathways

    Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2007
  13. Published

    Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

    Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2006
  15. Published

    Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

    Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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