- Published
c-Met activation promotes extravasation of hepatocellular carcinoma cells into 3D-cultured hepatocyte cells in lab-on-a-chip device
Bagci, G., Comez, D., Topel, Hande, Yilmaz, Y., Bagirsakci, E., Gunes, A., Batı Ayaz, G., Tahmaz, I., Bilgen, M., Solmaz, G., Pesen Okvur, D. & Atabey, N., Dec 2023, In: B B A - Molecular Cell Research. 1870, 8, p. 119557Research output: Contribution to journal › Journal article › Research › peer-review
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White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment
Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracing the biological roots of obesity resistance in humans
Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Time of day determines postexercise metabolism in mouse adipose tissue
Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling
Segref, A., Vakkayil, K. L., Padvitski, T., Li, Q., Kroef, V., Lormann, J., Körner, L., Finger, Fabian Michael & Hoppe, T., 2022, In: Nature Communications. 13, 1, 17 p., 5874.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The unidentified hormonal defense against weight gain
Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology of experimental overfeeding in animals
Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.Research output: Contribution to journal › Review › Research › peer-review
- Published
The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +
Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, , 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance
Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TNIK is a conserved regulator of glucose and lipid metabolism in obesity
Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THU-491-The role of alanine glyoxylate aminotransferase in hepatocellular carcinoma
Satriano, L., Lewinska, Monika, Rourke, C. O., Oliveira, D. V., Bhatt, D. K., Taranta, A., Herr, M., Straub, B., Conner, D. E. A., Budhu, D. A., Pomyen, Y., Ma, Tao, Gerhart-Hines, Zach, Stjernegaard, D. C. S., Matter, M., Crocoll, D. C., Wang, X. W., Marquardt, J. & Andersen, Jesper Bøje, 2019, p. e377.Research output: Contribution to conference › Poster › Research
- Published
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass, Frederike, Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 1 May 2021, In: Molecular Metabolism. 47, 19 p., 101173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis
Yılmaz, Y., Güneş, A., Topel, Hande & Atabey, N., Sep 2017, In: Journal of Gastrointestinal Cancer. 48, 3, p. 225-237 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine
Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, , 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma
Korhan, P., Yılmaz, Y., Bağırsakçı, E., Güneş, A., Topel, Hande, Carr, B. I. & Atabey, N., 2018, In: Canadian Journal of Gastroenterology. 2018, p. 7568742Research output: Contribution to journal › Review › Research › peer-review
- Published
Physiological protection against weight gain: evidence from overfeeding studies and future directions
Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, , 2021, In: Nature Communications. 12, 9 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
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NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
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MCT1 helps brown fat suck up succinate
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Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
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