- 2023
- Published
Loci for insulin processing and secretion provide insight into type 2 diabetes risk
Broadaway, K. A., Yin, X., Williamson, A., Parsons, V. A., Wilson, E. P., Moxley, A. H., Vadlamudi, S., Varshney, A., Jackson, A. U., Ahuja, V., Bornstein, S. R., Corbin, L. J., Delgado, G. E., Dwivedi, O. P., Silva, L. F., Frayling, T. M., Grallert, H., Gustafsson, S., Hakaste, L., Hammar, U. & 51 others, , 2023, In: American Journal of Human Genetics. 110, 2, p. 284-299 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M. K., Shringarpure, S. S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B. M., Thomas, L. F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J. V. T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A. & 112 others, , 2023, In: Nature Communications. 14, 6172.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents
Huang, Yun, Stinson, Sara, Juel, H. B., Lund, M. A. V., Holm, Louise Aas, Fonvig, Cilius Esmann, Nielsen, T., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, M., Chabanova, E., Thomsen, Henrik S., Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes
Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, Niels, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland
Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meal sugar-protein balance determines postprandial FGF21 response in humans
Ramne, Stina, Duizer, Lisanne, Nielsen, M. S., Jørgensen, Niklas Rye, Svenningsen, J. S., Grarup, Niels, Sjödin, Anders Mikael, Raben, Anne & Gillum, M. P., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 5, p. E491-E499Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives
Senftleber, N. K., Ramne, Stina, Moltke, Ida, Jørgensen, M. E., Albrechtsen, Anders, Hansen, Torben & Lepola, Mette Andersen, 2023, In: Application of Clinical Genetics. 16, p. 31-39 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
VA Million Veteran Program, V. M. V. P., 2023, medRxiv, 39 p.Research output: Working paper › Preprint › Research
- Published
A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
Thuesen, A. C. B., Stæger, F. F., Kaci, A., Solheim, M. H., Aukrust, I., Jørsboe, E., Santander, C. G., Andersen, M. K., Li, Z., Gilly, A., Stinson, S. E., Gjesing, A. P., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Bjørkhaug, L., Njølstad, P. R. & 3 others, , 2023, In: The Lancet Regional Health - Europe. 24, 12 p., 100529.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment
Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Maagensen, H., Kristiansen, M. R., Sørensen, H. T., Vaag, Allan, Beck-Nielsen, H., Pedersen, Oluf Borbye, Grarup, Niels, Nielsen, J. S., Rungby, Jørgen, Gjesing, A. P., Storgaard, H., Vilsbøll, Tina & Hansen, Torben, 2023, In: Molecular Genetics and Metabolism Reports. 35, 8 p., 100972.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation
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