- 2015
- Published
Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants
Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., Saxena, R., Scheer, F. A. J. L., Kovanen, L., Bartz, T. M., Perälä, M-M., Jonsson, A. E., Frazier-Wood, A. C., Kalafati, I-P., Mikkilä, V., Partonen, T. & 34 others, , Jan 2015, In: The American Journal of Clinical Nutrition. 101, 1, p. 135-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 31 others, , Jan 2015, In: P L o S Genetics. 11, 1, p. 1-25 25 p., e1004876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, , 29 Jan 2015, In: Nature Communications. 6, p. 5897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population
Justesen, Johanne Marie, Allin, K. H., Sandholt, C. H., Borglykke, A., Krarup, N. T., Grarup, Niels, Linneberg, Allan René, Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 24 Feb 2015, In: Circulation. Cardiovascular genetics. 8, p. 465-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes
Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, Niels & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data
Gjesing, A. M. P., Ribel-Madsen, R., Harder, M. N., Eiberg, Hans Rudolf Lytchoff, Grarup, Niels, Jørgensen, T., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye & Hansen, Torben, May 2015, In: Diabetologia. 58, 5, p. 1006-1012 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease
Gretarsdottir, S., Helgason, H., Helgadottir, A., Sigurdsson, A., Thorleifsson, G., Magnusdottir, A., Oddsson, A., Steinthorsdottir, V., Rafnar, T., de Graaf, J., Daneshpour, M. S., Hedayati, M., Azizi, F., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Eyjolfsson, G., Sigurdardottir, O., Olafsson, I. & 8 others, , Sep 2015, In: P L o S Genetics. 11, 9, 20 p., e1005379.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans
Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, Niels, Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval
Ghouse, Jonas, Have, C. T., Weeke, P., Nielsen, J. B., Ahlberg, G., Balslev-Harder, M., Appel, E. V., Skaaby, T., Olesen, S., Grarup, Niels, Linneberg, Allan René, Pedersen, Oluf Borbye, Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Salling Olesen, M., 1 Oct 2015, In: European Heart Journal. 36, 37, p. 2523-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, , 1 Oct 2015, In: P L o S Genetics. 11, 10, p. 1-42 42 p., e1005378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A., William Rayner, N., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Frånberg, M. & 31 others, , Dec 2015, In: Nature Genetics. 47, 12, p. 1415-25, 3 unpag. pages 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases
Hertz, C. L., Christiansen, S. L., Larsen, M. K., Dahl, M., Ferrero-Miliani, L., Weeke, P. E., Pedersen, Oluf Borbye, Hansen, Torben, Grarup, Niels, Ottesen, G. L., Frank-Hansen, R., Banner, Jytte & Morling, Niels, 2016, In: European Journal of Human Genetics. 24, p. 817–822Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of Type 2 diabetes: the power of isolated populations
Lepola, Mette Andersen, Pedersen, C. T., Moltke, Ida, Hansen, Torben, Albrechtsen, Anders & Grarup, Niels, 2016, In: Current Diabetes Reports. 16, 7, 9 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T. & 31 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, , 2016, In: Nature Communications. 7, 12 p., 10531.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, , 2016, In: Nature Communications. 7, 14 p., 10494.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders
Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, Niels, Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample
Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, , 1 Feb 2016, In: Nature Communications. 7, p. 1-15 15 p., 10495.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies
Husemoen, L. L. N., Skaaby, T., Thuesen, B. H., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Feb 2016, In: European Journal of Clinical Nutrition. 70, p. 613-619 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, , 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease
Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T. & 34 others, , 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2131-2141 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, , 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores link body fat distribution with specific cardiometabolic profiles
Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
CHARGE Consortium Hematology Working Group, C. C. H. W. G., Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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Latest publications
Genome-wide association study of preserved ratio impaired spirometry (PRISm)
Research output: Contribution to journal › Journal article › Research › peer-review
Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia
Research output: Contribution to journal › Journal article › Research › peer-review
GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
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