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Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives
Senftleber, N. K., Ramne, Stina, Moltke, Ida, Jørgensen, M. E., Albrechtsen, Anders, Hansen, Torben & Lepola, Mette Andersen, 2023, In: Application of Clinical Genetics. 16, p. 31-39 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A. & 32 others, , 2020, In: Diabetes. 69, 11, 93 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children
Hollensted, M., Fogh, M., Schnurr, T. M., Kloppenborg, J. T., Have, C. T., Nielsen, T. R. H., Rask, J., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Østergaard Johansen, M., Vincent Rosenbaum Appel, E., Mahendran, Y., Grarup, Niels, Kadarmideen, H. N., Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, 2018, In: Obesity. 26, 12, p. 1915-1922 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variant SLC2A2 Is Associated with Risk of Cardiovascular Disease - Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
Borglykke, A., Grarup, Niels, Sparsø, T., Linneberg, Allan René, Fenger, M., Jeppesen, J., Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., 2012, In: P L o S One. 7, 11, p. e50418Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function
Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, Petrine, Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, Allan René, Grarup, Niels, Jun, W., Pedersen, Oluf Borbye, Hansen, Torben & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J-W., Haessler, J., Lyytikäinen, L-P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. & 31 others, , 2022, In: Nature Communications. 13, 1, 18 p., 5144.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes
Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, Niels, Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data
Gjesing, A. M. P., Ribel-Madsen, R., Harder, M. N., Eiberg, Hans Rudolf Lytchoff, Grarup, Niels, Jørgensen, T., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye & Hansen, Torben, May 2015, In: Diabetologia. 58, 5, p. 1006-1012 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic architecture of obesity and related metabolic traits - recent insights from isolated populations
Lepola, Mette Andersen, Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2018, In: Current Opinion in Genetics and Development. 50, p. 74-78 5 p.Research output: Contribution to journal › Review › Research › peer-review
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Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, , 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, , 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic aspects of non-alcoholic fatty liver disease (NAFLD)
Stender, S., Grarup, Niels & Hansen, Torben, 2018, The Human Gut-Liver-Axis in Health and Disease. Springer, p. 195-206 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes
pjx571, pjx571, Appel, V. E., Schnurr, T. M., Lundby-Christensen, L., Skaaby, T., Linneberg, Allan René, Drivsholm, Thomas, Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & drb459, drb459, 2019, In: Diabetes and Vascular Disease Research. 16, 1, p. 13-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel, V. R., Moltke, Ida, Jørgensen, M. E., Bjerregaard, P., Linneberg, Allan René, Pedersen, Oluf Borbye, Albrechtsen, Anders, Hansen, Torben & Grarup, Niels, 2018, In: European Journal of Human Genetics. 26, 6, p. 868-875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic determinants of serum vitamin B12 and their relation to body mass index
Allin, K. H., Friedrich, N., Pietzner, M., Grarup, Niels, Thuesen, B. H., Linneberg, Allan René, Pisinger, C., Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In: European Journal of Epidemiology. 32, 2, p. 125–134Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels
Mahendran, Y., Jonsson, Anna Elisabet, Have, C. T., Allin, K. H., Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 10 Feb 2017, In: Diabetologia. 60, 5, p. 873-878 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A., William Rayner, N., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Frånberg, M. & 31 others, , Dec 2015, In: Nature Genetics. 47, 12, p. 1415-25, 3 unpag. pages 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic insights into resting heart rate and its role in cardiovascular disease
van de Vegte, Y. J., Eppinga, R. N., van der Ende, M. Y., Hagemeijer, Y. P., Mahendran, Y., Salfati, E., Smith, A. V., Tan, V. Y., Arking, D. E., Ntalla, I., Appel, E. V., Schurmann, C., Brody, J. A., Rueedi, R., Polasek, O., Sveinbjornsson, G., Lecoeur, C., Ladenvall, C., Zhao, J. H., Isaacs, A. & 31 others, , 2023, In: Nature Communications. 14, 4646.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases
Hertz, C. L., Christiansen, S. L., Larsen, M. K., Dahl, M., Ferrero-Miliani, L., Weeke, P. E., Pedersen, Oluf Borbye, Hansen, Torben, Grarup, Niels, Ottesen, G. L., Frank-Hansen, R., Banner, Jytte & Morling, Niels, 2016, In: European Journal of Human Genetics. 24, p. 817–822Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic markers of abdominal obesity and weight loss after gastric bypass surgery
Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Grarup, Niels, Burgdorf, Kristoffer Sølvsten, drb459, drb459, Pedersen, Oluf Borbye, Ängquist, Lars, Fenger, M., Sørensen, Thorkild I.A., Madsbad, Sten & Hansen, Torben, 2021, In: PLoS ONE. 16, 5, 11 p., 0252525.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents
Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Lintu, N., Lind, M. V., Atalay, M., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Larnkjær, A., Pedersen, O. B., Holm, J-C., Michaelsen, K. F., Lakka, T. A., Lehtimäki, T., Raitakari, O. & 2 others, , 2019, In: International Journal of Obesity. 43, p. 2007-2016 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic beta-cell function over 5 years of follow-up
Galijatovic, E. A. A., Allin, K. H., Sandholt, C. H., Borglykke, A., Lau, C. J., Ribel-Madsen, R., Sparsø, T., Justesen, Johanne Marie, Harder, M. N., Jørgensen, M. E., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 8 Jul 2013, In: Diabetes. 62, 10, p. 3610 3617 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk score of insulin resistance risk variants is associated with increased risk of coronary artery disease in patients referred to coronary angiography
Skals, R. K., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, S., Hansen, Torben, Grarup, Niels, Andersson, C., Torp-Pedersen, C. & Weeke, P. E., 2018, In: European Heart Journal. 39, p. 752-753Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention
Svendstrup, M., Allin, K. H., Sørensen, Thorkild I.A., Hansen, T. H., Grarup, Niels, Hansen, Torben & drb459, drb459, 2018, In: International Journal of Obesity. 42, 3, p. 370-375 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores link body fat distribution with specific cardiometabolic profiles
Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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