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A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads. / Rose, C S; Grarup, N; Krarup, N T; Poulsen, P; Wegner, L; Nielsen, Trine; Banasik, K; Faerch, K; Andersen, G; Albrechtsen, A; Borch-Johnsen, K; Clausen, J O; Jørgensen, T; Vaag, A; Pedersen, O; Hansen, T.
In:
Diabetologia, Vol. 52, No. 10, 2009, p. 2122-2129.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Rose, CS
, Grarup, N, Krarup, NT, Poulsen, P, Wegner, L, Nielsen, T
, Banasik, K, Faerch, K, Andersen, G
, Albrechtsen, A, Borch-Johnsen, K, Clausen, JO, Jørgensen, T
, Vaag, A, Pedersen, O & Hansen, T 2009, '
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads',
Diabetologia, vol. 52, no. 10, pp. 2122-2129.
https://doi.org/10.1007/s00125-009-1463-zAPA
Rose, C. S.
, Grarup, N., Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T.
, Banasik, K., Faerch, K., Andersen, G.
, Albrechtsen, A., Borch-Johnsen, K., Clausen, J. O., Jørgensen, T.
, Vaag, A., Pedersen, O., & Hansen, T. (2009).
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.
Diabetologia,
52(10), 2122-2129.
https://doi.org/10.1007/s00125-009-1463-zVancouver
Rose CS
, Grarup N, Krarup NT, Poulsen P, Wegner L, Nielsen T et al.
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.
Diabetologia. 2009;52(10):2122-2129.
https://doi.org/10.1007/s00125-009-1463-zAuthor
Rose, C S ; Grarup, N ; Krarup, N T ; Poulsen, P ; Wegner, L ; Nielsen, Trine ; Banasik, K ; Faerch, K ; Andersen, G ; Albrechtsen, A ; Borch-Johnsen, K ; Clausen, J O ; Jørgensen, T ; Vaag, A ; Pedersen, O ; Hansen, T. / A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads. In: Diabetologia. 2009 ; Vol. 52, No. 10. pp. 2122-2129.
Bibtex
@article{a48655b089b411df928f000ea68e967b,
title = "A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads",
abstract = "An association between elevated fasting plasma glucose and the common rs560887 G allele in the G6PC2/ABCB11 locus has been reported. In Danes we aimed to examine rs560887 in relation to plasma glucose and serum insulin responses following oral and i.v. glucose loads and in relation to hepatic glucose production during a hyperinsulinaemic-euglycaemic clamp. Furthermore, we examined rs560887 for association with impaired fasting glycaemia (IFG), impaired glucose tolerance (IGT), type 2 diabetes and components of the metabolic syndrome.",
keywords = "ATP-Binding Cassette Transporters, Adult, Blood Glucose, Fasting, Female, Genotype, Glucose, Glucose Tolerance Test, Glucose-6-Phosphatase, Humans, Insulin, Liver, Male, Middle Aged",
author = "Rose, {C S} and N Grarup and Krarup, {N T} and P Poulsen and L Wegner and Trine Nielsen and K Banasik and K Faerch and G Andersen and A Albrechtsen and K Borch-Johnsen and Clausen, {J O} and T J{\o}rgensen and A Vaag and O Pedersen and T Hansen",
note = "Export Date: 4 November 2009Source: Scopus",
year = "2009",
doi = "10.1007/s00125-009-1463-z",
language = "English",
volume = "52",
pages = "2122--2129",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "10",
}
RIS
TY - JOUR
T1 - A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads
AU - Rose, C S
AU - Grarup, N
AU - Krarup, N T
AU - Poulsen, P
AU - Wegner, L
AU - Nielsen, Trine
AU - Banasik, K
AU - Faerch, K
AU - Andersen, G
AU - Albrechtsen, A
AU - Borch-Johnsen, K
AU - Clausen, J O
AU - Jørgensen, T
AU - Vaag, A
AU - Pedersen, O
AU - Hansen, T
N1 - Export Date: 4 November 2009Source: Scopus
PY - 2009
Y1 - 2009
N2 - An association between elevated fasting plasma glucose and the common rs560887 G allele in the G6PC2/ABCB11 locus has been reported. In Danes we aimed to examine rs560887 in relation to plasma glucose and serum insulin responses following oral and i.v. glucose loads and in relation to hepatic glucose production during a hyperinsulinaemic-euglycaemic clamp. Furthermore, we examined rs560887 for association with impaired fasting glycaemia (IFG), impaired glucose tolerance (IGT), type 2 diabetes and components of the metabolic syndrome.
AB - An association between elevated fasting plasma glucose and the common rs560887 G allele in the G6PC2/ABCB11 locus has been reported. In Danes we aimed to examine rs560887 in relation to plasma glucose and serum insulin responses following oral and i.v. glucose loads and in relation to hepatic glucose production during a hyperinsulinaemic-euglycaemic clamp. Furthermore, we examined rs560887 for association with impaired fasting glycaemia (IFG), impaired glucose tolerance (IGT), type 2 diabetes and components of the metabolic syndrome.
KW - ATP-Binding Cassette Transporters
KW - Adult
KW - Blood Glucose
KW - Fasting
KW - Female
KW - Genotype
KW - Glucose
KW - Glucose Tolerance Test
KW - Glucose-6-Phosphatase
KW - Humans
KW - Insulin
KW - Liver
KW - Male
KW - Middle Aged
U2 - 10.1007/s00125-009-1463-z
DO - 10.1007/s00125-009-1463-z
M3 - Journal article
C2 - 19669124
VL - 52
SP - 2122
EP - 2129
JO - Diabetologia
JF - Diabetologia
SN - 0012-186X
IS - 10
ER -
