Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

Research output: Contribution to journalJournal articleResearchpeer-review

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Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. / Helgadottir, Anna; Gretarsdottir, Solveig; Thorleifsson, Gudmar; Holm, Hilma; Patel, Riyaz S; Gudnason, Thorarinn; Jones, Gregory T; van Rij, Andre M; Eapen, Danny J; Baas, Annette F; Tregouet, David-Alexandre; Morange, Pierre-Emmanuel; Emmerich, Joseph; Lindblad, Bengt; Gottsäter, Anders; Kiemeny, Lambertus A; Lindholt, Jes S.; Sakalihasan, Natzi; Ferrell, Robert E; Carey, David J; Elmore, James R; Tsao, Philip S; Grarup, Niels; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; Pola, Roberto; Gaetani, Eleonora; Magnadottir, Hulda B; Wijmenga, Cisca; Tromp, Gerard; Ronkainen, Antti; Ruigrok, Ynte M; Blankensteijn, Jan D; Mueller, Thomas; Wells, Philip S; Corral, Javier; Soria, Jose Manuel; Souto, Juan Carlos; Peden, John F; Jalilzadeh, Shapour; Mayosi, Bongani M; Keavney, Bernard; Strawbridge, Rona J; Sabater-Lleal, Maria; Gertow, Karl; Baldassarre, Damiano; Nyyssönen, Kristiina; Rauramaa, Rainer; Smit, Andries J; Mannarino, Elmo; Giral, Philippe; Tremoli, Elena; de Faire, Ulf; Humphries, Steve E; Hamsten, Anders; Haraldsdottir, Vilhelmina; Olafsson, Isleifur; Magnusson, Magnus K; Samani, Nilesh J; Levey, Allan I; Markus, Hugh S; Kostulas, Konstantinos; Dichgans, Martin; Berger, Klaus; Kuhlenbäumer, Gregor; Ringelstein, E Bernd; Stoll, Monika; Seedorf, Udo; Rothwell, Peter M; Powell, Janet T; Kuivaniemi, Helena; Onundarson, Pall T; Valdimarsson, Einar; Matthiasson, Stefan E; Gudbjartsson, Daniel F; Thorgeirsson, Guðmundur; Quyyumi, Arshed A; Watkins, Hugh; Farrall, Martin; Thorsteinsdottir, Unnur; Stefansson, Kari.

In: Journal of the American College of Cardiology, Vol. 60, No. 8, 2012, p. 722-9.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Helgadottir, A, Gretarsdottir, S, Thorleifsson, G, Holm, H, Patel, RS, Gudnason, T, Jones, GT, van Rij, AM, Eapen, DJ, Baas, AF, Tregouet, D-A, Morange, P-E, Emmerich, J, Lindblad, B, Gottsäter, A, Kiemeny, LA, Lindholt, JS, Sakalihasan, N, Ferrell, RE, Carey, DJ, Elmore, JR, Tsao, PS, Grarup, N, Jørgensen, T, Witte, DR, Hansen, T, Pedersen, O, Pola, R, Gaetani, E, Magnadottir, HB, Wijmenga, C, Tromp, G, Ronkainen, A, Ruigrok, YM, Blankensteijn, JD, Mueller, T, Wells, PS, Corral, J, Soria, JM, Souto, JC, Peden, JF, Jalilzadeh, S, Mayosi, BM, Keavney, B, Strawbridge, RJ, Sabater-Lleal, M, Gertow, K, Baldassarre, D, Nyyssönen, K, Rauramaa, R, Smit, AJ, Mannarino, E, Giral, P, Tremoli, E, de Faire, U, Humphries, SE, Hamsten, A, Haraldsdottir, V, Olafsson, I, Magnusson, MK, Samani, NJ, Levey, AI, Markus, HS, Kostulas, K, Dichgans, M, Berger, K, Kuhlenbäumer, G, Ringelstein, EB, Stoll, M, Seedorf, U, Rothwell, PM, Powell, JT, Kuivaniemi, H, Onundarson, PT, Valdimarsson, E, Matthiasson, SE, Gudbjartsson, DF, Thorgeirsson, G, Quyyumi, AA, Watkins, H, Farrall, M, Thorsteinsdottir, U & Stefansson, K 2012, 'Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism', Journal of the American College of Cardiology, vol. 60, no. 8, pp. 722-9. https://doi.org/10.1016/j.jacc.2012.01.078

APA

Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., Gudnason, T., Jones, G. T., van Rij, A. M., Eapen, D. J., Baas, A. F., Tregouet, D-A., Morange, P-E., Emmerich, J., Lindblad, B., Gottsäter, A., Kiemeny, L. A., Lindholt, J. S., Sakalihasan, N., Ferrell, R. E., ... Stefansson, K. (2012). Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. Journal of the American College of Cardiology, 60(8), 722-9. https://doi.org/10.1016/j.jacc.2012.01.078

Vancouver

Helgadottir A, Gretarsdottir S, Thorleifsson G, Holm H, Patel RS, Gudnason T et al. Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. Journal of the American College of Cardiology. 2012;60(8):722-9. https://doi.org/10.1016/j.jacc.2012.01.078

Author

Helgadottir, Anna ; Gretarsdottir, Solveig ; Thorleifsson, Gudmar ; Holm, Hilma ; Patel, Riyaz S ; Gudnason, Thorarinn ; Jones, Gregory T ; van Rij, Andre M ; Eapen, Danny J ; Baas, Annette F ; Tregouet, David-Alexandre ; Morange, Pierre-Emmanuel ; Emmerich, Joseph ; Lindblad, Bengt ; Gottsäter, Anders ; Kiemeny, Lambertus A ; Lindholt, Jes S. ; Sakalihasan, Natzi ; Ferrell, Robert E ; Carey, David J ; Elmore, James R ; Tsao, Philip S ; Grarup, Niels ; Jørgensen, Torben ; Witte, Daniel R ; Hansen, Torben ; Pedersen, Oluf ; Pola, Roberto ; Gaetani, Eleonora ; Magnadottir, Hulda B ; Wijmenga, Cisca ; Tromp, Gerard ; Ronkainen, Antti ; Ruigrok, Ynte M ; Blankensteijn, Jan D ; Mueller, Thomas ; Wells, Philip S ; Corral, Javier ; Soria, Jose Manuel ; Souto, Juan Carlos ; Peden, John F ; Jalilzadeh, Shapour ; Mayosi, Bongani M ; Keavney, Bernard ; Strawbridge, Rona J ; Sabater-Lleal, Maria ; Gertow, Karl ; Baldassarre, Damiano ; Nyyssönen, Kristiina ; Rauramaa, Rainer ; Smit, Andries J ; Mannarino, Elmo ; Giral, Philippe ; Tremoli, Elena ; de Faire, Ulf ; Humphries, Steve E ; Hamsten, Anders ; Haraldsdottir, Vilhelmina ; Olafsson, Isleifur ; Magnusson, Magnus K ; Samani, Nilesh J ; Levey, Allan I ; Markus, Hugh S ; Kostulas, Konstantinos ; Dichgans, Martin ; Berger, Klaus ; Kuhlenbäumer, Gregor ; Ringelstein, E Bernd ; Stoll, Monika ; Seedorf, Udo ; Rothwell, Peter M ; Powell, Janet T ; Kuivaniemi, Helena ; Onundarson, Pall T ; Valdimarsson, Einar ; Matthiasson, Stefan E ; Gudbjartsson, Daniel F ; Thorgeirsson, Guðmundur ; Quyyumi, Arshed A ; Watkins, Hugh ; Farrall, Martin ; Thorsteinsdottir, Unnur ; Stefansson, Kari. / Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. In: Journal of the American College of Cardiology. 2012 ; Vol. 60, No. 8. pp. 722-9.

Bibtex

@article{13c8a2ca6021405ea6db62e1981ed855,
title = "Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism",
abstract = "The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components.",
keywords = "African Americans, Age of Onset, Angiography, Aortic Aneurysm, Abdominal, Apolipoproteins A, Atherosclerosis, Brain Ischemia, Carotid Intima-Media Thickness, Coronary Artery Disease, European Continental Ancestry Group, Genetic Predisposition to Disease, Humans, Intracranial Aneurysm, Linear Models, Logistic Models, Myocardial Infarction, Odds Ratio, Peripheral Arterial Disease, Polymorphism, Single Nucleotide, Risk Factors, Severity of Illness Index, Stroke, Venous Thromboembolism",
author = "Anna Helgadottir and Solveig Gretarsdottir and Gudmar Thorleifsson and Hilma Holm and Patel, {Riyaz S} and Thorarinn Gudnason and Jones, {Gregory T} and {van Rij}, {Andre M} and Eapen, {Danny J} and Baas, {Annette F} and David-Alexandre Tregouet and Pierre-Emmanuel Morange and Joseph Emmerich and Bengt Lindblad and Anders Gotts{\"a}ter and Kiemeny, {Lambertus A} and Lindholt, {Jes S.} and Natzi Sakalihasan and Ferrell, {Robert E} and Carey, {David J} and Elmore, {James R} and Tsao, {Philip S} and Niels Grarup and Torben J{\o}rgensen and Witte, {Daniel R} and Torben Hansen and Oluf Pedersen and Roberto Pola and Eleonora Gaetani and Magnadottir, {Hulda B} and Cisca Wijmenga and Gerard Tromp and Antti Ronkainen and Ruigrok, {Ynte M} and Blankensteijn, {Jan D} and Thomas Mueller and Wells, {Philip S} and Javier Corral and Soria, {Jose Manuel} and Souto, {Juan Carlos} and Peden, {John F} and Shapour Jalilzadeh and Mayosi, {Bongani M} and Bernard Keavney and Strawbridge, {Rona J} and Maria Sabater-Lleal and Karl Gertow and Damiano Baldassarre and Kristiina Nyyss{\"o}nen and Rainer Rauramaa and Smit, {Andries J} and Elmo Mannarino and Philippe Giral and Elena Tremoli and {de Faire}, Ulf and Humphries, {Steve E} and Anders Hamsten and Vilhelmina Haraldsdottir and Isleifur Olafsson and Magnusson, {Magnus K} and Samani, {Nilesh J} and Levey, {Allan I} and Markus, {Hugh S} and Konstantinos Kostulas and Martin Dichgans and Klaus Berger and Gregor Kuhlenb{\"a}umer and Ringelstein, {E Bernd} and Monika Stoll and Udo Seedorf and Rothwell, {Peter M} and Powell, {Janet T} and Helena Kuivaniemi and Onundarson, {Pall T} and Einar Valdimarsson and Matthiasson, {Stefan E} and Gudbjartsson, {Daniel F} and Gu{\dh}mundur Thorgeirsson and Quyyumi, {Arshed A} and Hugh Watkins and Martin Farrall and Unnur Thorsteinsdottir and Kari Stefansson",
note = "Copyright {\textcopyright} 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.",
year = "2012",
doi = "10.1016/j.jacc.2012.01.078",
language = "English",
volume = "60",
pages = "722--9",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier",
number = "8",

}

RIS

TY - JOUR

T1 - Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

AU - Helgadottir, Anna

AU - Gretarsdottir, Solveig

AU - Thorleifsson, Gudmar

AU - Holm, Hilma

AU - Patel, Riyaz S

AU - Gudnason, Thorarinn

AU - Jones, Gregory T

AU - van Rij, Andre M

AU - Eapen, Danny J

AU - Baas, Annette F

AU - Tregouet, David-Alexandre

AU - Morange, Pierre-Emmanuel

AU - Emmerich, Joseph

AU - Lindblad, Bengt

AU - Gottsäter, Anders

AU - Kiemeny, Lambertus A

AU - Lindholt, Jes S.

AU - Sakalihasan, Natzi

AU - Ferrell, Robert E

AU - Carey, David J

AU - Elmore, James R

AU - Tsao, Philip S

AU - Grarup, Niels

AU - Jørgensen, Torben

AU - Witte, Daniel R

AU - Hansen, Torben

AU - Pedersen, Oluf

AU - Pola, Roberto

AU - Gaetani, Eleonora

AU - Magnadottir, Hulda B

AU - Wijmenga, Cisca

AU - Tromp, Gerard

AU - Ronkainen, Antti

AU - Ruigrok, Ynte M

AU - Blankensteijn, Jan D

AU - Mueller, Thomas

AU - Wells, Philip S

AU - Corral, Javier

AU - Soria, Jose Manuel

AU - Souto, Juan Carlos

AU - Peden, John F

AU - Jalilzadeh, Shapour

AU - Mayosi, Bongani M

AU - Keavney, Bernard

AU - Strawbridge, Rona J

AU - Sabater-Lleal, Maria

AU - Gertow, Karl

AU - Baldassarre, Damiano

AU - Nyyssönen, Kristiina

AU - Rauramaa, Rainer

AU - Smit, Andries J

AU - Mannarino, Elmo

AU - Giral, Philippe

AU - Tremoli, Elena

AU - de Faire, Ulf

AU - Humphries, Steve E

AU - Hamsten, Anders

AU - Haraldsdottir, Vilhelmina

AU - Olafsson, Isleifur

AU - Magnusson, Magnus K

AU - Samani, Nilesh J

AU - Levey, Allan I

AU - Markus, Hugh S

AU - Kostulas, Konstantinos

AU - Dichgans, Martin

AU - Berger, Klaus

AU - Kuhlenbäumer, Gregor

AU - Ringelstein, E Bernd

AU - Stoll, Monika

AU - Seedorf, Udo

AU - Rothwell, Peter M

AU - Powell, Janet T

AU - Kuivaniemi, Helena

AU - Onundarson, Pall T

AU - Valdimarsson, Einar

AU - Matthiasson, Stefan E

AU - Gudbjartsson, Daniel F

AU - Thorgeirsson, Guðmundur

AU - Quyyumi, Arshed A

AU - Watkins, Hugh

AU - Farrall, Martin

AU - Thorsteinsdottir, Unnur

AU - Stefansson, Kari

N1 - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

PY - 2012

Y1 - 2012

N2 - The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components.

AB - The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components.

KW - African Americans

KW - Age of Onset

KW - Angiography

KW - Aortic Aneurysm, Abdominal

KW - Apolipoproteins A

KW - Atherosclerosis

KW - Brain Ischemia

KW - Carotid Intima-Media Thickness

KW - Coronary Artery Disease

KW - European Continental Ancestry Group

KW - Genetic Predisposition to Disease

KW - Humans

KW - Intracranial Aneurysm

KW - Linear Models

KW - Logistic Models

KW - Myocardial Infarction

KW - Odds Ratio

KW - Peripheral Arterial Disease

KW - Polymorphism, Single Nucleotide

KW - Risk Factors

KW - Severity of Illness Index

KW - Stroke

KW - Venous Thromboembolism

U2 - 10.1016/j.jacc.2012.01.078

DO - 10.1016/j.jacc.2012.01.078

M3 - Journal article

C2 - 22898070

VL - 60

SP - 722

EP - 729

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 8

ER -

ID: 43218607