Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Research output: Contribution to journal › Journal article › Research › peer-review
The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been reported to associate with insulin resistance.
| Original language | English |
|---|---|
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 92 |
| Issue number | 1 |
| Pages (from-to) | 363-6 |
| Number of pages | 4 |
| ISSN | 0021-972X |
| DOIs | |
| Publication status | Published - 2007 |
- Adult, Cohort Studies, Diabetes Mellitus, Type 2, European Continental Ancestry Group, Female, Humans, Insulin Resistance, Iodide Peroxidase, Male, Middle Aged, Obesity, Phenotype, Polymorphism, Genetic
Research areas
ID: 38336359