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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. / Voight, Benjamin F; Scott, Laura J; Steinthorsdottir, Valgerdur; Morris, Andrew P; Dina, Christian; Welch, Ryan P; Zeggini, Eleftheria; Huth, Cornelia; Aulchenko, Yurii S; Thorleifsson, Gudmar; McCulloch, Laura J; Ferreira, Teresa; Grallert, Harald; Amin, Najaf; Wu, Guanming; Willer, Cristen J; Raychaudhuri, Soumya; McCarroll, Steve A; Langenberg, Claudia; Hofmann, Oliver M; Dupuis, Josée; Qi, Lu; Segrè, Ayellet V; van Hoek, Mandy; Navarro, Pau; Ardlie, Kristin; Balkau, Beverley; Benediktsson, Rafn; Bennett, Amanda J; Blagieva, Roza; Boerwinkle, Eric; Bonnycastle, Lori L; Bengtsson Boström, Kristina; Bravenboer, Bert; Bumpstead, Suzannah; Burtt, Noisël P; Charpentier, Guillaume; Chines, Peter S; Cornelis, Marilyn; Couper, David J; Crawford, Gabe; Doney, Alex S F; Elliott, Katherine S; Elliott, Amanda L; Erdos, Michael R; Grarup, Niels; Jørgensen, Torben; Sparsø, Thomas; Hansen, Torben; Pedersen, Oluf; MAGIC investigators.
In:
Nature Genetics, Vol. 42, No. 7, 01.07.2010, p. 579-89.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Voight, BF, Scott, LJ, Steinthorsdottir, V, Morris, AP, Dina, C, Welch, RP, Zeggini, E, Huth, C, Aulchenko, YS, Thorleifsson, G, McCulloch, LJ, Ferreira, T, Grallert, H, Amin, N, Wu, G, Willer, CJ, Raychaudhuri, S, McCarroll, SA, Langenberg, C, Hofmann, OM, Dupuis, J, Qi, L, Segrè, AV, van Hoek, M, Navarro, P, Ardlie, K, Balkau, B, Benediktsson, R, Bennett, AJ, Blagieva, R, Boerwinkle, E, Bonnycastle, LL, Bengtsson Boström, K, Bravenboer, B, Bumpstead, S, Burtt, NP, Charpentier, G, Chines, PS, Cornelis, M, Couper, DJ, Crawford, G, Doney, ASF, Elliott, KS, Elliott, AL, Erdos, MR
, Grarup, N, Jørgensen, T, Sparsø, T
, Hansen, T, Pedersen, O & MAGIC investigators 2010, '
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis',
Nature Genetics, vol. 42, no. 7, pp. 579-89.
https://doi.org/10.1038/ng.609APA
Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., ... MAGIC investigators (2010).
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
Nature Genetics,
42(7), 579-89.
https://doi.org/10.1038/ng.609Vancouver
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP et al.
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
Nature Genetics. 2010 Jul 1;42(7):579-89.
https://doi.org/10.1038/ng.609Author
Voight, Benjamin F ; Scott, Laura J ; Steinthorsdottir, Valgerdur ; Morris, Andrew P ; Dina, Christian ; Welch, Ryan P ; Zeggini, Eleftheria ; Huth, Cornelia ; Aulchenko, Yurii S ; Thorleifsson, Gudmar ; McCulloch, Laura J ; Ferreira, Teresa ; Grallert, Harald ; Amin, Najaf ; Wu, Guanming ; Willer, Cristen J ; Raychaudhuri, Soumya ; McCarroll, Steve A ; Langenberg, Claudia ; Hofmann, Oliver M ; Dupuis, Josée ; Qi, Lu ; Segrè, Ayellet V ; van Hoek, Mandy ; Navarro, Pau ; Ardlie, Kristin ; Balkau, Beverley ; Benediktsson, Rafn ; Bennett, Amanda J ; Blagieva, Roza ; Boerwinkle, Eric ; Bonnycastle, Lori L ; Bengtsson Boström, Kristina ; Bravenboer, Bert ; Bumpstead, Suzannah ; Burtt, Noisël P ; Charpentier, Guillaume ; Chines, Peter S ; Cornelis, Marilyn ; Couper, David J ; Crawford, Gabe ; Doney, Alex S F ; Elliott, Katherine S ; Elliott, Amanda L ; Erdos, Michael R ; Grarup, Niels ; Jørgensen, Torben ; Sparsø, Thomas ; Hansen, Torben ; Pedersen, Oluf ; MAGIC investigators. / Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. In: Nature Genetics. 2010 ; Vol. 42, No. 7. pp. 579-89.
Bibtex
@article{3f4bd66a39564476a3ff4f18bb8a46e1,
title = "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis",
abstract = "By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D) and 38,987 controls of European descent and following up previously unidentified meta-analysis signals in a further 34,412 cases and 59,925 controls, we identified 12 new T2D association signals with combined P",
keywords = "Blood Glucose, Diabetes Mellitus, Type 2, Dual-Specificity Phosphatases, Fasting, Gene Dosage, Gene Expression Profiling, Genetic Heterogeneity, Genetic Predisposition to Disease, Genome, Human, Genome-Wide Association Study, Hepatocyte Nuclear Factor 1-alpha, Humans, KCNQ1 Potassium Channel, Meta-Analysis as Topic, Mitogen-Activated Protein Kinase Phosphatases, Polymorphism, Single Nucleotide",
author = "Voight, {Benjamin F} and Scott, {Laura J} and Valgerdur Steinthorsdottir and Morris, {Andrew P} and Christian Dina and Welch, {Ryan P} and Eleftheria Zeggini and Cornelia Huth and Aulchenko, {Yurii S} and Gudmar Thorleifsson and McCulloch, {Laura J} and Teresa Ferreira and Harald Grallert and Najaf Amin and Guanming Wu and Willer, {Cristen J} and Soumya Raychaudhuri and McCarroll, {Steve A} and Claudia Langenberg and Hofmann, {Oliver M} and Jos{\'e}e Dupuis and Lu Qi and Segr{\`e}, {Ayellet V} and {van Hoek}, Mandy and Pau Navarro and Kristin Ardlie and Beverley Balkau and Rafn Benediktsson and Bennett, {Amanda J} and Roza Blagieva and Eric Boerwinkle and Bonnycastle, {Lori L} and {Bengtsson Bostr{\"o}m}, Kristina and Bert Bravenboer and Suzannah Bumpstead and Burtt, {Nois{\"e}l P} and Guillaume Charpentier and Chines, {Peter S} and Marilyn Cornelis and Couper, {David J} and Gabe Crawford and Doney, {Alex S F} and Elliott, {Katherine S} and Elliott, {Amanda L} and Erdos, {Michael R} and Niels Grarup and Torben J{\o}rgensen and Thomas Spars{\o} and Torben Hansen and Oluf Pedersen and {MAGIC investigators}",
year = "2010",
month = jul,
day = "1",
doi = "10.1038/ng.609",
language = "English",
volume = "42",
pages = "579--89",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "nature publishing group",
number = "7",
}
RIS
TY - JOUR
T1 - Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
AU - Voight, Benjamin F
AU - Scott, Laura J
AU - Steinthorsdottir, Valgerdur
AU - Morris, Andrew P
AU - Dina, Christian
AU - Welch, Ryan P
AU - Zeggini, Eleftheria
AU - Huth, Cornelia
AU - Aulchenko, Yurii S
AU - Thorleifsson, Gudmar
AU - McCulloch, Laura J
AU - Ferreira, Teresa
AU - Grallert, Harald
AU - Amin, Najaf
AU - Wu, Guanming
AU - Willer, Cristen J
AU - Raychaudhuri, Soumya
AU - McCarroll, Steve A
AU - Langenberg, Claudia
AU - Hofmann, Oliver M
AU - Dupuis, Josée
AU - Qi, Lu
AU - Segrè, Ayellet V
AU - van Hoek, Mandy
AU - Navarro, Pau
AU - Ardlie, Kristin
AU - Balkau, Beverley
AU - Benediktsson, Rafn
AU - Bennett, Amanda J
AU - Blagieva, Roza
AU - Boerwinkle, Eric
AU - Bonnycastle, Lori L
AU - Bengtsson Boström, Kristina
AU - Bravenboer, Bert
AU - Bumpstead, Suzannah
AU - Burtt, Noisël P
AU - Charpentier, Guillaume
AU - Chines, Peter S
AU - Cornelis, Marilyn
AU - Couper, David J
AU - Crawford, Gabe
AU - Doney, Alex S F
AU - Elliott, Katherine S
AU - Elliott, Amanda L
AU - Erdos, Michael R
AU - Grarup, Niels
AU - Jørgensen, Torben
AU - Sparsø, Thomas
AU - Hansen, Torben
AU - Pedersen, Oluf
AU - MAGIC investigators
PY - 2010/7/1
Y1 - 2010/7/1
N2 - By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D) and 38,987 controls of European descent and following up previously unidentified meta-analysis signals in a further 34,412 cases and 59,925 controls, we identified 12 new T2D association signals with combined P
AB - By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D) and 38,987 controls of European descent and following up previously unidentified meta-analysis signals in a further 34,412 cases and 59,925 controls, we identified 12 new T2D association signals with combined P
KW - Blood Glucose
KW - Diabetes Mellitus, Type 2
KW - Dual-Specificity Phosphatases
KW - Fasting
KW - Gene Dosage
KW - Gene Expression Profiling
KW - Genetic Heterogeneity
KW - Genetic Predisposition to Disease
KW - Genome, Human
KW - Genome-Wide Association Study
KW - Hepatocyte Nuclear Factor 1-alpha
KW - Humans
KW - KCNQ1 Potassium Channel
KW - Meta-Analysis as Topic
KW - Mitogen-Activated Protein Kinase Phosphatases
KW - Polymorphism, Single Nucleotide
U2 - 10.1038/ng.609
DO - 10.1038/ng.609
M3 - Journal article
C2 - 20581827
VL - 42
SP - 579
EP - 589
JO - Nature Genetics
JF - Nature Genetics
SN - 1061-4036
IS - 7
ER -
