Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
Research output: Contribution to journal › Journal article › Research › peer-review
The fetal insulin hypothesis suggests that variation in the fetal genotype influencing insulin secretion or action may predispose to low birthweight and type 2 diabetes. We examined associations between 25 confirmed type 2 diabetes risk variants and birthweight in individuals from the Danish Inter99 population and in meta-analyses including Inter99 data and reported studies.
| Original language | English |
|---|---|
| Journal | Diabetologia |
| Volume | 53 |
| Issue number | 9 |
| Pages (from-to) | 1908-16 |
| Number of pages | 9 |
| ISSN | 0012-186X |
| DOIs | |
| Publication status | Published - 1 Sep 2010 |
- Adenylate Cyclase, Alleles, Birth Weight, Cyclin-Dependent Kinase 5, Diabetes Mellitus, Type 2, Female, Genome-Wide Association Study, Genotype, Homeodomain Proteins, Humans, Infant, Newborn, Pregnancy, Transcription Factors
Research areas
ID: 33506369