Grarup Group

  1. 2022
  2. Published

    A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

    Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Zhao, J. H., Aadahl, Mette, Bork-Jensen, J., Møllehave, L. T., Liu, J., Wang, J., drb459, drb459, Jackson, R. D., Kovacs, P., Pedersen, Oluf Borbye, Hansen, Torben, Lind, L., Loos, Ruth, Christensen, K., Linneberg, Allan René, Grarup, Niels, Dantoft, T. M., Karpe, F., Wei, W. Q., Sun, Y. V., Million Veterans Program, M. V. P. & Global Lipids Genetics Consortium, G. L. G. C., 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A novel nonsense variant in EXOC8 underlies a neurodevelopmental disorder

    Ullah, Asmat, Krishin, J., Haider, N., Aurangzeb, B., Abdullah, Suleman, Sufyan, Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Neurogenetics. 23, p. 203-212

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S., Ferreira, T., Highland, H. H., Ji, Y., Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, Jun, Mollehave, L. T., Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention

    Jørsboe, E., Lepola, Mette Andersen, Skotte, L., Stæger, Frederik Filip Vinggaard, Færgeman, N. J., Hanghøj, Kristian Ebbesen, Santander, Cindy, Senftleber, N. K., Diaz, L. J., Overvad, M., Waples, R. K., Geller, F., Bjerregaard, P., Melbye, Mads, Larsen, C. V. L., Feenstra, B., Anders Koch, K., Jørgensen, M. E., Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2022, In: Human Genetics and Genomics Advances. 3, 4, 10 p., 100118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents

    Huang, Yun, Stinson, Sara, Juel, H. B., Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, C. E., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, Michael, Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2022, In: Journal of Hepatology. 77, p. S450-S450 1 p., FRI104.

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis

    Skaaby, T., Oskari Kilpeläinen, Tuomas, Mahendran, Y., Huang, Lam Opal, Sallis, H., Thuesen, B. H., Kårhus, L. L., Leth-Møller, K. B., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2022, In: European Journal of Epidemiology. 37, p. 713-722

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

    Wei, T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, Johanne Marie, Chen, I. Y., Wo, H., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J., Yeh, C., Yang, K., Lau, E., Lynch, K. L., Rivas, M., Kobilka, B. K. & Wu, J. C., 2022, In: Cell. 185, 10, p. 1676-1693.e23

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study

    Durda, P., Raffield, L. M., Lange, E. M., Olson, N. C., Jenny, N. S., Cushman, M., Deichgraeber, P., Grarup, Niels, Jonsson, Anna Elisabet, Hansen, Torben, Mychaleckyj, J. C., Psaty, B. M., Reiner, A. P., Tracy, R. P. & Lange, L. A., 2022, In: Journal of the American Heart Association. 11, 21, 14 p., e024374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine

    Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, C., Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, In: medRxiv. 17 p.

    Research output: Contribution to journalJournal articleResearch

  11. Published

    Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

    Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J., Haessler, J., Lyytikäinen, L., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S., Freudling, R., Hines, O., Isaksen, Jonas L., Lin, H., Mei, H., Moscati, A., Müller-Nurasyid, M., Nursyifa, Casia, Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-Santos, E., Thériault, S., van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, Gustav, Andreasen, Laura Korsholm, Ellervik, C., Hansen, Torben, Jackson, R. D., Lind, L., Linneberg, Allan René, Grarup, Niels, Kanters, Jørgen K., Loos, Ruth, Olesen, Morten Steen Salling & CHARGE Consortium, C. C., 2022, In: Nature Communications. 13, 1, 18 p., 5144.

    Research output: Contribution to journalJournal articleResearchpeer-review

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