Hansen Group

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  1. 2019
  2. Published

    Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations

    Andersson, C., Krogager, M. L., Skals, R. K., Appel, E. V. R., Have, C. T., Grarup, N., Pedersen, O., Jeppesen, J. L., Pedersen, O. D., Dominguez, H., Dixen, U., Engstrøm, T., Tønder, N., Roden, D. M., Stender, S., Gislason, G. H., Enghusen-Poulsen, H., Hansen, T., Køber, L., Torp-Pedersen, C. & 1 others, Weeke, P. E., 2019, In: P L o S One. 14, 2, 12 p., e0211690.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Breastfeeding duration in infancy and adult risks of type 2 diabetes in a high-income country

    Bjerregaard, L. G., Pedersen, D. C., Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Maternal and Child Nutrition. 15, 4, 9 p., e12869.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training

    Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

    Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Helgeland, O., Horikoshi, M., Karhunen, V., Lowry, E., Cousminer, D. L., Ahluwalia, T. S., Thiering, E., Boh, E. T-H., Zafarmand, M. H., Vilor-Tejedor, N., Wang, C. A., Joro, R., Chen, Z., Gauderman, W. J., Pitkanen, N., Parra, E. J. & 79 others, Fernandez-Rhodes, L., Alyass, A., Monnereau, C., Curtin, J. A., Have, C. T., McCormack, S. E., Hollensted, M., Frithioff-Bojsoe, C., Valladares-Salgado, A., Peralta-Romero, J., Teo, Y., Standl, M., Leinonen, J. T., Holm, Jens-Christian, Peters, T., Vioque, J., Vrijheid, M., Simpson, A., Custovic, A., Vaudel, M., Canouil, M., Lindi, V., Atalay, M., Kahonen, M., Raitakari, O. T., van Schaik, B. D. C., Berkowitz, R. I., Cole, S. A., Voruganti, V. S., Wang, Y., Highland, H. M., Comuzzie, A. G., Butte, N. F., Justice, A. E., Gahagan, S., Blanco, E., Lehtimaki, T., Lakka, T. A., Hebebrand, J., Bonnefond, A., Grarup, Niels, Froguel, P., Lyytikainen, L., Cruz, M., Kobes, S., Hanson, R. L., Zemel, B. S., Hinney, A., Teo, K. K., Meyre, D., North, K. E., Gilliland, F. D., Bisgaard, H., Bustamante, M., Bønnelykke, Klaus, Pennell, C. E., Rivadeneira, F., Uitterlinden, A. G., Baier, L. J., Vrijkotte, T. G. M., Heinrich, J., Sørensen, Thorkild I.A., Saw, S., Pedersen, Oluf Borbye, Hansen, Torben, Eriksson, J., Widen, E., McCarthy, M. I., Njolstad, P. R., Power, C., Hypponen, E., Sebert, S., Brown, C. D., Jarvelin, M., Timpson, N. J., Johansson, S., Hakonarson, H., Jaddoe, V. W. V. & Grant, S. F. A., 2019, In: Human Molecular Genetics. 28, 19, p. 3327-3338

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

    Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?

    Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  8. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes

    Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  9. Published

    Polygenic predisposition to breast cancer and the risk of coronary artery disease

    D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, Niels, Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

    Drivsholm, A., Lund, Morten Asp Vonsild, Hedley, P. L., Jespersen, Thomas, Christiansen, M., Hansen, Torben & Holm, Jens-Christian, 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 12, p. 1351-1358

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

    Ehmann, D., Wendler, J., Koeninger, L., Larsen, I. S., Klag, T., Berger, J., Marette, A., Schaller, M., Stange, E. F., Malek, N. P., Jensen, Benjamin Anderschou Holbech & Wehkamp, J., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3746-3751

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes

    pjx571, pjx571, Appel, V. E., Schnurr, T. M., Lundby-Christensen, L., Skaaby, T., Linneberg, Allan René, Drivsholm, Thomas, Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & drb459, drb459, 2019, In: Diabetes and Vascular Disease Research. 16, 1, p. 13-21 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Haploinsufficiency of ARHGAP42 is associated with hypertension

    Fjorder, A. S., Rasmussen, Malene Bøgehus, Mehrjouy, M. M., Nazaryan-Petersen, L., Hansen, C., Bak, M., Grarup, Niels, Nørremølle, Anne, Larsen, Lars Allan, drb459, drb459, Hansen, Torben, Tommerup, Niels & Bache, Iben, 2019, In: European Journal of Human Genetics. 27, 8, p. 1296-1303 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

    Broad Genomics Platform, B. G. P., Jun 2019, In: Nature. 570, 7759, p. 71-76 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Glucose metabolism in children and adolescents: Population-based reference values and comparisons to children and adolescents enrolled in obesity treatment

    Frithioff-Bøjsøe, C., Lund, Morten Asp Vonsild, Kloppenborg, J. T., Nielsen, T. T. H., Fonvig, Cilius Esmann, Lausten-Thomsen, U., Hedley, P. L., Hansen, T., Pedersen, Oluf Borbye, Christiansen, M., Baker, J. L., Hansen, Torben & Holm, Jens-Christian, 2019, In: Pediatric Diabetes. 20, 5, p. 538-548

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Extracellular Vesicle Encapsulated MicroRNAs in Patients with Type 2 Diabetes Are Affected by Metformin Treatment

    Ghai, V., Kim, T., Etheridge, A., Nielsen, T., Hansen, Torben, Pedersen, Oluf Borbye, Galas, D. & Wang, K., 2019, In: Journal of Clinical Medicine. 8, 17 p., 617.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Reference values for fasting serum concentrations of thyroid-stimulating hormone and thyroid hormones in healthy Danish/North-European white children and adolescents

    Gunapalasingham, G., Frithioff-Bojsoe, C., Lund, Morten Asp Vonsild, Hedley, P. L., Fonvig, Cilius Esmann, Dahl, M., Pedersen, Oluf Borbye, Christiansen, M., Hansen, Torben, Lausten-Thomsen, U. & Holm, Jens-Christian, 2019, In: Scandinavian Journal of Clinical & Laboratory Investigation. 79, 1-2, p. 129-135

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

    Hartwig, F. P., Davies, N. M., Horta, B. L., Ahluwalia, T. S., Bisgaard, H., Bønnelykke, K., Caspi, A., Moffitt, T. E., Poulton, R., Sajjad, A., Tiemeier, H. W., Dalmau-Bueno, A., Guxens, M., Bustamante, M., Santa-Marina, L., Parker, N., Paus, T., Pausova, Z., Lauritzen, L., Schnurr, T. M. & 7 others, Michaelsen, Kim F., Hansen, Torben, Oddy, W., Pennell, C. E., Warrington, N. M., Davey Smith, G. & Victora, C. G., 2019, In: International Journal of Epidemiology. 48, 1, p. 45-57 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

    Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J-F., Ahluwalia, T. V. S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T. O., Kleber, M. E. & 31 others, Crozier, S. R., Godfrey, K. M., Lemaitre, R., Felix, J. F., Shi, Y., Gupta, P., Khor, C., Lehtimäki, T., Wang, C. A., Tiesler, C. M. T., Thiering, E., Standl, M., Rzehak, P., Marouli, E., He, M., Lecoeur, C., Corella, D., Lai, C., Moreno, L. A., Pitkänen, N., Boreham, C. A., Zhang, T., Hansen, Torben, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Bisgaard, H., Pedersen, Oluf Borbye, Bønnelykke, Klaus, Rossing, Peter & BIRTH-GENE (BIG) Study Working Group, B. (. S. W. G., 2019, In: JAMA Network Open. 2, 9, 18 p., e1910915.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies

    Huang, T., Sun, D., Heianza, Y., Bergholdt, H. K. M., Gao, M., Fang, Z., Ding, M., Frazier-Wood, A. C., North, K. E., Marouli, E., Graff, M., Smith, C. E., Varbo, A., Lemaitre, R. N., Corella, D., Wang, C. A., Tjønneland, A., Overvad, K., Sørensen, T. I. A., Feitosa, M. F. & 36 others, Wojczynski, M. K., Kahonen, M., Mikkila, V., Bartz, T. M., Psaty, B. M., Siscovick, D. S., Danning, R. D., Dedoussis, G., Pedersen, Oluf Borbye, Hansen, Torben, Havulinna, A. S., Mannisto, S., Rotter, J. I., Sares-Jaske, L., Allison, M. A., Rich, S. S., Sorli, J. V., Coltell, O., Pennell, C. E., Eastwood, P., Ridker, P. M., Viikari, J., Raitakari, O., Lehtimaki, T., Helminen, M., Wang, Y., Deloukas, P., Knekt, P., Kanerva, N., Kilpeläinen, Tuomas O., Province, M. A., Mozaffarian, D., Chasman, D. I., Nordestgaard, B. G., Ellervik, Christina & Qi, L., 2019, In: Clinical Chemistry. 65, 6, p. 751-760 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Obesity and unfavourable lifestyle increase type 2 diabetes-risk independent of genetic predisposition

    Jakupovic, Hermina, Schnurr, T. M., Carrasquilla, Germán D., Grarup, Niels, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: Diabetologia. 62, Suppl. 1, p. S188 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  23. Published

    Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Jørgensen, T., Justesen, Johanne Marie, Karpe, F., Kovacs, P., Li, J., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Pers, Tune H, drb459, drb459, Zhao, J. H., Loos, R. J. F. & CHD Exome+ Consortium, C. E. C., 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice

    Kashani, A., Brejnrod, A. D., Jin, C., Kern, T., Madsen, A. N., Holm, L. A., Gerber, G. K., Holm, Jens-Christian, Hansen, Torben, Holst, Birgitte & Arumugam, Mani, 2019, In: Animal Microbiome. 1, 1, 16 p., 11.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

    Research output: Contribution to journal › Journal article › Research › peer-review

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