Hansen Group

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

Skaaby, T., Taylor, A. E., Jacobsen, R. K., Paternoster, L., Thuesen, B. H., Ahluwalia, T. S., Larsen, S. C., Zhou, A., Wong, A., Gabrielsen, M. E., Bjørngaard, J. H., Flexeder, C., Männistö, S., Hardy, R., Kuh, D., Barry, S. J., Tang Møllehave, L., Cerqueira, C., Friedrich, N., Bonten, T. N. & 34 others, Noordam, R., Mook-Kanamori, D. O., Taube, C., Jessen, L. E., McConnachie, A., Sattar, N., Upton, M. N., McSharry, C., Bønnelykke, Klaus, Bisgaard, H., Schulz, H., Strauch, K., Meitinger, T., Peters, A., Grallert, H., Nohr, E. A., Kivimaki, M., Kumari, M., Völker, U., Nauck, M., Völzke, H., Power, C., Hyppönen, E., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye, Salomaa, V., Grarup, Niels, Langhammer, A., Romundstad, P. R., Skorpen, F., Kaprio, J., R Munafò, M. & Linneberg, Allan René, 2017, In: Scientific Reports. 7, 1, 9 p., 2224.

Research output: Contribution to journal › Journal article › Research › peer-review

Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation

Fredheim, S., Svensson, Jannet, Pørksen, S., Hansen, L., Hansen, Torben, Pedersen, Oluf Borbye, Mortensen, H. B., Barbetti, F. & Nielsen, L. B., 2011, In: Case Reports in Genetics. 2011, p. 258978

Research output: Contribution to journal › Journal article › Research › peer-review

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

The International Genomics of Blood Pressure (iGEN-BP) Consortium, T. I. G. O. B. P. (. C., 2018, In: Nature Communications. 9, 5052.

Research output: Contribution to journal › Journal article › Research › peer-review

Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD

Schnurr, T. M., Katz, S. F., Justesen, Johanne Marie, O'Sullivan, J. W., Saliba-Gustafsson, P., Assimes, T. L., Carcamo-Orive, I., Ahmed, A., Ashley, E. A., Hansen, Torben & Knowles, J. W., 2022, In: Hepatology Communications. 6, 7, p. 1516-1526

Research output: Contribution to journal › Journal article › Research › peer-review

Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population

Justesen, Johanne Marie, Allin, K. H., Sandholt, C. H., Borglykke, A., Krarup, N. T., Grarup, Niels, Linneberg, Allan René, Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 24 Feb 2015, In: Circulation. Cardiovascular genetics. 8, p. 465-72 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference

Olsen, N. J., Ängquist, Lars, Larsen, S. C., Linneberg, Allan René, Skaaby, T., Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Tjønneland, A., Halkjær, J., Hansen, Torben, Pedersen, Oluf Borbye, Overvad, K., Ahluwalia, T. S., Sørensen, Thorkild I.A. & Heitmann, Berit, 2016, In: American Journal of Clinical Nutrition. 104, 3, p. 816-826 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation

Frederiksen, T. C., Christiansen, M. K., Benjamin, E. J., Overvad, K., Olsen, A., Lepola, Mette Andersen, Hansen, Torben, Grarup, Niels, Jensen, H. K. & Dahm, C. C., 2024, In: Heart. 110, p. :644–649

Research output: Contribution to journal › Journal article › Research › peer-review

Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference

Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, Berit & Sørensen, Thorkild I.A., Apr 2014, In: The American Journal of Clinical Nutrition. 99, 4

Research output: Contribution to journal › Journal article › Research › peer-review

Interaction between genetic predisposition to adiposity and dietary protein in relation to subsequent change in body weight and waist circumference

Ankarfeldt, Mikkel Zöllner, Larsen, S. C., Ängquist, Lars, Husemoen, L. L. N., Roswall, N., Overvad, K., Jakobsen, M. U., Halkjær, J., Tjønneland, A., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Hansen, Torben, Pedersen, Oluf Borbye, Heitmann, Berit, Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 10, 10 p., e110890.

Research output: Contribution to journal › Journal article › Research › peer-review

Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes

Borges, M. C., Clayton, G. L., Freathy, R. M., Felix, J. F., Fernández-Sanlés, A., Soares, A. G., Kilpi, F., Yang, Q., McEachan, R. R. C., Richmond, R. C., Liu, X., Skotte, L., Irizar, A., Hattersley, A. T., Bodinier, B., Scholtens, D. M., Nohr, E. A., Bond, T. A., Hayes, M. G., West, J. & 20 others, Tyrrell, J., Wright, J., Bouchard, L., Murcia, M., Bustamante, M., Chadeau-Hyam, M., Jarvelin, M., Vrijheid, M., Perron, P., Magnus, P., Gaillard, R., Jaddoe, V. W. V., Lowe, W. L., Feenstra, B., Hivert, M., Sørensen, Thorkild I.A., Håberg, S. E., Serbert, S., Magnus, M. & Lawlor, D. A., 2024, In: BMC Medicine. 22, 14 p., 32.

Research output: Contribution to journal › Journal article › Research › peer-review

Intake of macro- and micronutrients in Danish vegans

Kristensen, N. B., Madsen, M. L., Hansen, T. H., Allin, K. H., Hoppe, C., Fagt, S., Lausten, M. S., Gøbel, R. J., drb459, drb459, Hansen, Torben & Pedersen, Oluf Borbye, 30 Oct 2015, In: Nutrition Journal. 14, 1, p. 1-10 10 p., 115.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin resistance genetic risk score and burden of coronary artery disease in patients referred for coronary angiography

Skals, R., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, Steen, Hansen, Torben, Grarup, Niels, Lee, C. J., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2021, In: PLoS ONE. 16, 6, 11 p., 0252855.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin resistance and impaired pancreatic beta-cell function in adult offspring of women with diabetes in pregnancy

Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 24 Jun 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin Resistance and Impaired Pancreatic β-Cell Function in Adult Offspring of Women With Diabetes in Pregnancy

Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality

Blond, K., Carslake, D., Gjærde, L. K., Vistisen, D., Sørensen, Thorkild I.A., Smith, G. D. & Baker, J. L., 2021, In: Scientific Reports. 11, 1, 10 p., 22408.

Research output: Contribution to journal › Journal article › Research › peer-review

Insights into metabolic disease from studying genetics in isolated populations: stories from Greece to Greenland

Zeggini, E., Gloyn, A. L. & Hansen, Torben, 18 Mar 2016, In: Diabetologia. 59, 5, p. 938-941 4 p.

Research output: Contribution to journal › Review › Research › peer-review

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, Holm, Jens-Christian, Mardis, E., Fulton, R., Pui, C., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, Kjeld, Loh, M. L., Relling, M. V. & Yang, J. J., 2015, In: Nature Communications. 6, p. 1-7 7 p., 7553.

Research output: Contribution to journal › Journal article › Research › peer-review

Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.

Research output: Contribution to journal › Journal article › Research › peer-review

Infections increase the risk of decompensation and death in patients with early alcohol-related liver disease

Johansen, S., Langkjær, S., Rasmussen, D. N., Israelsen, M., Torp, N., Lindvig, K., Kjærgaard, M., Hansen, J. K., Hansen, C. D., Thorhauge, K., Andersen, P., Detlefsen, S., Juel, H. B., Justesen, U. S., Hansen, Torben, Krag, A., Thiele, M., GALAXY and MicrobLiver consortia, G. A. M. C. & MicrobLiver Consortium, M. C., 2024, In: JHEP Reports. 6, 4, 10 p., 101016.

Research output: Contribution to journal › Journal article › Research › peer-review

Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele

Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy

Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, Holst, Jens Juul & Damm, Peter, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1967-75 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, Niels, Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Increased liver fat associates with severe metabolic perturbations in low birth weight men

Brøns, C., Thuesen, Anne Cathrine Baun, Elingaard-Larsen, L. O., Justesen, L., Jensen, Rasmus Tanderup, Henriksen, Nicolai Stevns, Juel, H. B., Størling, Joachim, Ried-Larsen, M., Sparks, L. M., van Hall, Gerrit, Danielsen, E. R., Hansen, Torben & Vaag, Allan, 2022, In: European Journal of Endocrinology. 186, 5, p. 511-521 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes

Niazi, R. K., Sun, J., Have, C. T., Hollensted, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Grarup, Niels, Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 1, p. 1-12 e0210114.

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus

'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M. H., Holst, Jens Juul, De Koning, E. J., Häring, H. U., Pedersen, O., Groop, L., De Geus, E. J., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M., Pearson, E. R. & Diamant, M., 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133

Research output: Contribution to journal › Comment/debate › Research › peer-review

Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes

Bille, D. S., Banasik, Karina, Justesen, Johanne Marie, Sandholt, C. H., Sandbæk, A., Lauritzen, T., Jørgensen, T., Witte, D. R., Holm, Jens-Christian, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jun 2011, In: P L o S One. 6, 6, p. e20640 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C. & 519 others, Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Havulinna, A. S., Veturi, Y., Pacheco, J. A., Rosenthal, E. A., Lingren, T., Feng, Q. P., Kullo, I. J., Narita, A., Takayama, J., Martin, H. C., Hunt, K. A., Trivedi, B., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Rasheed, A., Hindy, G., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Choudhury, A., Sengupta, D., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J. H., Matsuda, F., Jang, H. M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Yousri, N. A., Mitchell, R. E., Chai, J. F., Aadahl, Mette, Bjerregaard, A. A., Yao, J., Manichaikul, A., Hwu, C. M., Hung, Y. J., Warren, H. R., Ramirez, J., Bork-Jensen, J., Kårhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Mauro, P., Matteo, F., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, L. T., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Ruotsalainen, S. E., Daw, E., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Vazquez-Moreno, M., Feitosa, M. F., Wojczynski, M. K., Wang, Z., Preuss, M. H., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Tsao, N. L., Verma, A., Slieker, R. C., Lo, K. S., Zilhao, N. R., Le, P., Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Demirkan, A., Leonard, H. L., Marten, J., Frank, M., Schmidt, B., Smyth, L. J., Cañadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kähönen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Nongmaithem, S. S., Bayyana, S., Stringham, H. M., Irvin, M. R., Oldmeadow, C., Kim, H. N., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Prasad, G., Lorés-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Banas, B., Nardone, G. G., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A. E., Hofer, E., Lin, M., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkänen, N., Cade, B. E., van der Laan, S. W., Chitrala, K. N., Weiss, S., Bentley, A. R., Doumatey, A. P., Adeyemo, A. A., Lee, J. Y., Petersen, E. R. B., Nielsen, A. A., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S. Y., Wang, J. S., Couture, C., Lyytikäinen, L. P., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hidalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Liang, J., Tang, H., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Kawaguchi, T., Thiery, J., Bis, J. C., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jäger, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X. O., Rallidis, L. S., Pedersen, Oluf Borbye, Hansen, Torben, Mitchell, P., Hewitt, A. W., Kähönen, M., Pérusse, L., Bouchard, C., Tönjes, A., Chen, Y. D. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellström, D., Cho, Y. S., Lee, H., Yuan, J. M., Koh, W. P., Rhee, S. Y., Woo, J. T., Heid, I. M., Stark, K. J., Zimmermann, M. E., Völzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Peyser, P. A., Kato, N., Schulze, M. B., Girotto, G., Böger, C. A., Jung, B., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Tusié-Luna, T., Aguilar-Salinas, C. A., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J. Y., Zheng, W., Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C. K., Nelson, A. E., Golightly, Y. M., Wilson, J. F., Penninx, B., Kim, H. L., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Hunt, S. C., Walker, M., Koistinen, H. A., Chandak, G. R., Mercader, J. M., Costanzo, M. C., Jang, D., Burtt, N. P., Villalpando, C. G., Orozco, L., Fornage, M., Tai, E., van Dam, R. M., Lehtimäki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jöckel, K. H., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Jin, Z. B., Qu, J., Hishigaki, H., Lin, X., März, W., Gudnason, V., Tardif, J. C., Lettre, G., Hart, L. M. T., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, Ruth, Province, M. A., Parra, E. J., Cruz, M., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Rotimi, C. N., Christensen, K., Ripatti, S., Widén, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, Allan René, Jukema, J. W., Khera, A. V., Männikkö, M., Jarvelin, M. R., Kutalik, Z., Francesco, C., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, Niels, Sever, P., Poulter, N., Chuang, L. M., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C. Y., Wong, T. Y., Khor, C. C., Li, H., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., Willemsen, A. H. M., Cupples, L., van Meurs, J. B. J., Ghanbari, M., Gordon-Larsen, P., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., Hazelhurst, S., Ramsay, M., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Baras, A., Justice, A. E., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Tamiya, G., Yamamoto, M., van Heel, D. A., Trembath, R. C., Wei, W. Q., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Åsvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Kim, B. J., Thorsteinsdottir, U., Stefansson, K., Zhang, J., Chen, Y., Ho, Y. L., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K. M., Cho, K., O'Donnell, C. J., Gaziano, J. M., Wilson, P. W. F., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Mohlke, K. L., Sun, Y. V., Morris, A. P., Boehnke, M., Brown, C. D., Natarajan, P., Deloukas, P., Willer, C. J., Assimes, T. L. & Peloso, G. M., 2022, In: Genome Biology. 23, 1, 42 p., 268.

Research output: Contribution to journal › Journal article › Research › peer-review

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

Belda, E., Voland, L., Tremaroli, V., Falony, G., Adriouch, S., Assmann, K. E., Prifiti, E., Aron-Wisnewsky, J., Debedat, J., Le Roy, T., Nielsen, T., Amouyal, C., Andre, S., Andreelli, F., Blueher, M., Chakaroun, R., Chilloux, J., Coelho, L. P., Dao, M. C., Das, P. & 42 others, Fellahi, S., Forslund, S., Galleron, N., Hansen, T. H., Holmes, B., Ji, B., Pedersen, H. K., Phuong Le, Le Chatelier, E., Lewinter, C., Manneras-Holm, L., Marquet, F., Myridakis, A., Pelloux, V., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J., Sokolovska, N., Søndertoft, N. B., Touch, S., Vieira-Silva, S., Galan, P., Holst, Jens Juul, Gøtze, J. P., Køber, Lars Valeur, drb459, drb459, Hansen, Torben, Hercberg, S., Oppert, J., Nielsen, J., Letunic, I., Dumas, M., Stumvoll, M., Pedersen, Oluf Borbye, Bork, P., Ehrlich, S. D., Zucker, J., Baeckhed, F., Raes, J. & Clement, K., 2022, In: Gut. 71, 12, p. 2463-2480 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice

Kashani, A., Brejnrod, A. D., Jin, C., Kern, T., Madsen, A. N., Holm, L. A., Gerber, G. K., Holm, Jens-Christian, Hansen, Torben, Holst, Birgitte & Arumugam, Mani, 2019, In: Animal Microbiome. 1, 1, 16 p., 11.

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity

Kloppenborg, J. T., Fonvig, Cilius Esmann, Nielsen, T. R. H., Mollerup, P. M., Bøjsøe, C., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, May 2018, In: Pediatric Diabetes. 19, 3, p. 356-365

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

Dimas, A. S., Lagou, V., Barker, A., Knowles, J. W., Mägi, R., Hivert, M-F., Benazzo, A., Rybin, D., Jackson, A. U., Stringham, H. M., Song, C., Fischer-Rosinsky, A., Boesgaard, T. W., Grarup, N., Abbasi, F. A., Assimes, T. L., Hao, K., Yang, X., Lecoeur, C., Barroso, I. & 31 others, Bonnycastle, L. L., Böttcher, Y., Bumpstead, S., Chines, P. S., Erdos, M. R., Graessler, J., Kovacs, P., Morken, M. A., Narisu, N., Payne, F., Stancakova, A., Swift, A. J., Tönjes, A., Bornstein, S. R., Cauchi, S., Froguel, P., Meyre, D., Schwarz, P. E. H., Häring, H., Smith, U., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Quertemous, T., Lind, L., Hansen, Torben, Pedersen, Oluf Borbye, Walker, M. & on behalf of the MAGIC investigators, O. B. O. T. M. I., 2 Dec 2013, In: Diabetes. 63, 6, p. 2158-2171 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

Rönn, T., Volkov, P., Gillberg, L., Kokosar, M., Perfilyev, A., Jacobsen, A. L., Jørgensen, S. W., Brøns, C., Jansson, P., Eriksson, K., Pedersen, Oluf Borbye, Hansen, Torben, Groop, L., Stener-Victorin, E., Vaag, Allan, Nilsson, E. & Ling, C., 1 Jul 2015, In: Human Molecular Genetics. 24, 13, p. 3792-813 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of acute alcohol consumption on circulating microbiome in asymptomatic alcohol-related liver disease

Israelsen, M., Alvarez Silva, Maria Camila, Madsen, B. S., Hansen, C. D., Torp, N. C., Johansen, S., Hansen, J. K., Prier Lindvig, K., Insonere, J., Riviere, V., Juel, H. B., Brejnrod, A., Jensen, Lars Juhl, Thiele, M., Lelouvier, B., Hansen, Torben, Arumugam, Mani & Krag, A., 2024, In: Gut. 73, 6, p. 1041-1044 gutjnl-2023-330360.

Research output: Contribution to journal › Letter › Research › peer-review

Impact of abdominal obesity on postprandial lipid concentrations

Christiansen, Malene Revsbech, Sørensen, Thorkild I.A., Hansen, Torben & Kilpeläinen, Tuomas O., 2020, In: European Journal of Human Genetics. 28, Suppl. 1, p. 279-280 2 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Impact of a vegan diet on the human salivary microbiota

Hansen, T. H., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Nielsen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, p. 1-11 5847.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes

Hansen, T. H., drb459, drb459, Jørgensen, T., Jørgensen, M. E., Lauritzen, T., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Hansen, Torben & Gjesing, A. M. P., 20 Mar 2015, In: BMC Medical Genetics. 16, p. 1-9 9 p., 17.

Research output: Contribution to journal › Journal article › Research › peer-review

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

Molinaro, A., Bel Lassen, P., Henricsson, M., Wu, H., Adriouch, S., Belda, E., Chakaroun, R., Nielsen, T., Bergh, P-O., Rouault, C., Andre, S., Marquet, F., Andreelli, F., Salem, J-E., Assmann, K., Bastard, J-P., Forslund, S., Le Chatelier, E., Falony, G., Pons, N. & 26 others, Prifti, E., Quinquis, B., Roume, H., Vieira-Silva, S., Hansen, T. H., Pedersen, H. K., Lewinter, C., Sønderskov, N. B., Køber, Lars Valeur, Vestergaard, H., Hansen, Torben, Zucker, J., Galan, P., Dumas, M., Raes, J., Oppert, J., Letunic, I., Nielsen, J., Bork, P., Ehrlich, S. D., Stumvoll, M., Pedersen, Oluf Borbye, Aron-Wisneswky, J., Clement, K., Baeckhed, F. & MetaCardis Consortium, M. C., 2020, In: Nature Communications. 11, 1, 10 p., 5881.

Research output: Contribution to journal › Journal article › Research › peer-review

Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing

Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña, E., Thuesen, Anne Cathrine Baun, Hussain, M., Stæger, Frederik Filip Vinggaard, Gjesing, A. P., Albrechtsen, Anders & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 13 p., 1128850.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment

Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Maagensen, H., Kristiansen, M. R., Sørensen, H. T., Vaag, Allan, Beck-Nielsen, H., Pedersen, Oluf Borbye, Grarup, Niels, Nielsen, J. S., Rungby, Jørgen, Gjesing, A. P., Storgaard, H., Vilsbøll, Tina & Hansen, Torben, 2023, In: Molecular Genetics and Metabolism Reports. 35, 8 p., 100972.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia

Akbar, W., Ullah, A., Haider, N., Suleman, Sufyan, Khan, F. U., Shah, A. A., Sikandar, M. A., Basit, S. & Ahmad, W., 2024, In: Journal of Gene Medicine. 26, 1, 10 p., e3601.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders

Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, Niels, Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity

Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Grarup, Niels, Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Ahmad, W., Gul, A. & Hansen, Torben, 2018, In: BMC Medical Genetics. 19, 1, p. 1-8 199.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

Steinthorsdottir, V., Thorleifsson, G., Sulem, P., Helgason, H., Grarup, N., Sigurdsson, A., Helgadottir, H. T., Johannsdottir, H., Magnusson, O. T., Gudjonsson, S. A., Justesen, J. M., Harder, M. N., Jørgensen, M. E., Christensen, C., Brandslund, I., Sandbæk, A., Lauritzen, T., Vestergaard, H., Linneberg, A., Jørgensen, T. & 14 others, Hansen, Torben, Daneshpour, M. S., Fallah, M., Hreidarsson, A. B., Sigurdsson, G., Azizi, F., Benediktsson, R., Masson, G., Helgason, A., Kong, A., Gudbjartsson, D. F., Pedersen, Oluf Borbye, Thorsteinsdottir, U. & Stefansson, K., 26 Jan 2014, In: Nature Genetics. 46, 3, p. 294-300 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of genetic variants associated with a wide spectrum of phenotypes clinically diagnosed as Sanfilippo and Morquio syndromes using whole genome sequencing

Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña Lozano, Elionora, Thuesen, Anne Cathrine Baun, Gjesing, A. P., Hussain, M., Tufail, M., Saqib, M., Afshan, K. & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 14 p., 1254909.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

Echwald, S. M., Bjørbaek, C., Hansen, Torben, Clausen, J. O., drb459, drb459, Zierath, Juleen R, Printz, R. L., Granner, D. K. & Pedersen, Oluf Borbye, Mar 1995, In: Diabetes. 44, 3, p. 347-53 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of Mislabeled Samples and Sample Mix-ups in Genotype Data using Barcode Genotypes

Have, C. T., Appel, E. V. R., Grarup, Niels, Hansen, Torben & Bork-Jensen, J., 2014, In: International Journal of Bioscience, Biochemistry and Bioinformatics. 4, 5, p. 355-360 5 p., 370.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, Torben, Hildebrand, F., Kaas, R. S., Kennedy, S., Kristiansen, Karsten, Kultima, J. R., Léonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, Oluf Borbye, Prifti, E., Qin, J., Raes, J., Sørensen, Søren Johannes, Tap, J., Tims, S., Ussery, D., Yamada, T., Renault, P., Sicheritz-Pontén, T., Bork, P., Wang, J. & MetaHIT Consortium, M. C., 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review