- 2020
- Published
Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study
Obura, M., Beulens, J. W. J., Slieker, R., Koopman, A. D. M., Hoekstra, T., Nijpels, G., Elders, P., Koivula, R. W., Kurbasic, A., Laakso, M., Hansen, T. H., Ridderstråle, M., Hansen, T., Pavo, I., Forgie, I., Jablonka, B., Ruetten, H., Mari, A., McCarthy, M. I., Walker, M. & 19 others, , 2020, In: PLoS ONE. 15, 11, 11 p., e0242360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland
Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.Research output: Contribution to journal › Journal article › Research › peer-review
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Associations of childhood BMI and change in BMI from childhood to adulthood with risks of hypertensive disorders in pregnancy
Pedersen, D. C., Bjerregaard, L. G., Nohr, E. A., Rasmussen, K. M. & Baker, J. L., 2020, In: American Journal of Clinical Nutrition. 112, 5, p. 1180-1187 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes and correlations in height from 7 to 69 years of age across the birth years of 1930 to 1989
Pedersen, D. C., Meyle, K. D., Ängquist, Lars, Andersen, Ingelise, Tjønneland, Anne, Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Aarestrup, J. & Baker, J. L., 2020, In: American Journal of Human Biology. 32, 4, e23378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr−/− ApoB100/100 mice
Perazza, L. R., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech, Daniel, N., Boyer, M., Varin, T. V., Bouchareb, R., Nachbar, R. T., Bouchard, M., Blais, M., Gagné, A., Joubert, P., Sweeney, G., Roy, D., Arsenault, B. J., Mathieu, P. & Marette, A., 2020, In: Atherosclerosis. 304, p. 9-21 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study
Schnurr, T. M., Jakupovic, Hermina, Carrasquilla, Germán D., Ängquist, Lars, Grarup, Niels, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2020, In: Diabetologia. 63, 7, p. 1324-1332 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood
Schnurr, T. M., Morgen, C. S., Borisevich, D., Beaumont, R. N., pjx571, pjx571, Ängquist, Lars, Have, C. T., Freathy, R. M., Smith, G. D., Nohr, E. A., Hansen, Torben & Sørensen, Thorkild I.A., 2020, In: Scientific Reports. 10, 1, 10 p., 4806.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet
Senftleber, N., Jørgensen, M. E., Jørsboe, E., Imamura, F., Forouhi, N. G., Larsen, C. L., Bjerregaard, P., Hansen, Torben & Albrechtsen, Anders, 2020, In: European Journal of Human Genetics. 28, 11, p. 1592-1601 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 34 others, , 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal microbiome is a co-determinant of the postprandial plasma glucose response
Søndertoft, N. B., Vogt, J. K., Arumugam, Mani, Kristensen, M., Gøbel, R. J., Fan, Yong, Lyu, Liwei, Bahl, M. I., Eriksen, C., Ängquist, Lars, Frøkiær, Hanne, Hansen, T. H., Brix, Susanne, Nielsen, H. B., Hansen, Torben, Vestergaard, H., Gupta, R., Licht, T. R., Lauritzen, Lotte & Pedersen, Oluf Borbye, 2020, In: P L o S One. 15, 9, 23 p., e0238648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size and its associations with adult bladder cancer
Sørensen, K. K., Jensen, B. W., Thomas, P. E., Madsen, K., Eriksson, Frank, Aarestrup, J. & Baker, J. L., 2020, In: Annals of Human Biology. 47, 2, p. 166-172 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size, growth and risks of systemic lupus erythematosus: A large Danish observational cohort study
Thomas, P. E., Jensen, B. W., Sørensen, K. K., Jacobsen, Søren, Aarestrup, J. & Baker, J. L., 2020, In: Seminars in Arthritis and Rheumatism. 50, 6, p. 1507-1512 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Describing the fecal metabolome in cryogenically collected samples from healthy participants
Trošt, K., Ahonen, L., Suvitaival, T., Christiansen, N., Nielsen, T., Thiele, M., Jacobsen, S., Krag, A., Rossing, Peter, Hansen, Torben, Dragsted, Lars Ove & Legido-Quigley, C., 2020, In: Scientific Reports. 10, 1, 8 p., 885.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, , 2020, In: Nature. 581, 7808, p. 310-315Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
Vogelezang, S., Bradfield, J. P., Ahluwalia, Tarun Veer Singh, Curtin, J. A., Grarup, Niels, Schnurr, T. M., Hansen, Torben, Michaelsen, Kim F., Pedersen, Oluf Borbye, Stokholm, Jakob, Lind, M. V., Frithioff-Bøjsøe, C., Holm, Jens-Christian, Felix, J. F. & Early Growth Genetics Consortium, E. G. G. C., 2020, In: P L o S Genetics. 16, 10, 26 p., e1008718.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Polygenic and Monogenic Basis of Blood Traits and Diseases
Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., Ritchie, S. C., Megy, K., Ponstingl, H., Penkett, C. J., Albers, P. K., Wigdor, E. M., Sakaue, S., Moscati, A., Manansala, R., Lo, K. S. & 31 others, , 2020, In: Cell. 182, 5, p. 1214-1231 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation
Weng, L. C., Hall, A. W., Choi, S. H., Jurgens, S. J., Haessler, J., Bihlmeyer, N. A., Grarup, N., Lin, H., Teumer, A., Li-Gao, R., Yao, J., Guo, X., Brody, J. A., Müller-Nurasyid, M., Schramm, K., Verweij, N., van den Berg, M. E., van Setten, J., Isaacs, A., Ramírez, J. & 40 others, , 2020, In: Circulation. Genomic and precision medicine. 13, 5, p. 387-395 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism
Williams, K., Ingerslev, L. R., Bork-Jensen, J., Wohlwend, M., Hansen, Ann Normann, Small, Lewin Barkla, Ribel-Madsen, R., Astrup, A., Pedersen, Oluf Borbye, Auwerx, J., Workman, C. T., Grarup, Niels, Hansen, Torben & Barrès, Romain, 2020, In: Nature Communications. 11, 16 p., 2695.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria
Winther, S. A., Henriksen, P., Vogt, J. K., Hansen, T. H., Ahonen, L., Suvitaival, T., Zobel, E. H., Frimodt-Møller, M., Hansen, T. W., Hansen, Torben, Parving, H., Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2020, In: Diabetologia. 63, p. 2713-2724 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A. & 32 others, , 2020, In: Diabetes. 69, 11, 93 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report
Zhang, J., Juhl, C. R., Hylten-Cavallius, L., Olesen, Morten Steen Salling, Linneberg, Allan René, Holst, Jens Juul, Hansen, Torben, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: B M C Endocrine Disorders. 20, 5 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood
Zheng, Y., Huang, T., Wang, T., Mei, Z., Sun, Z., Zhang, T., Ellervik, C., Chai, J-F., Sim, X., van Dam, R. M., Tai, E-S., Koh, W-P., Dorajoo, R., Saw, S-M., Sabanayagam, C., Wong, T. Y., Gupta, P., Rossing, P., Ahluwalia, T. S., Vinding, R. K. & 98 others, , 2020, In: European Journal of Epidemiology. 35, p. 685–697 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Birthweight and risk of thyroid cancer and its histological types: A large cohort study
Aarestrup, J., Kitahara, C. M. & Baker, J. L., 2019, In: Cancer Epidemiology. 62, 101564.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood Overweight, Tallness, and Growth Increase Risks of Ovarian Cancer
Aarestrup, J., Trabert, B., Ulrich, L. G., Wentzensen, N., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Cancer Epidemiology, Biomarkers & Prevention. 28, 1, p. 183-188Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Weight Loss After Bariatric Surgery
Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats
Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Wegener, G. & Lund, S., 2019, In: European Neuropsychopharmacology. 29, 1, p. 98-110Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels and Changes in Childhood Body Mass Index in Relation to Risk of Atrial Fibrillation and Atrial Flutter in Adulthood
Adelborg, K., Ängquist, Lars, Ording, A., Gjærde, L. K., Bjerregaard, L. G., Sørensen, H. T., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: American Journal of Epidemiology. 188, 4, p. 684-693 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria
Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jorgensen, M. E., Grarup, N. & 9 others, , 2019, In: Diabetologia. 62, 2, p. 292-305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of Latent Autoimmune Diabetes in Adults
Lepola, Mette Andersen & Hansen, Torben, 2019, In: Current Diabetes Reviews. 15, 3, p. 194-198 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations
Andersson, C., Krogager, M. L., Skals, R. K., Appel, E. V. R., Have, C. T., Grarup, N., Pedersen, O., Jeppesen, J. L., Pedersen, O. D., Dominguez, H., Dixen, U., Engstrøm, T., Tønder, N., Roden, D. M., Stender, S., Gislason, G. H., Enghusen-Poulsen, H., Hansen, T., Køber, L., Torp-Pedersen, C. & 1 others, , 2019, In: P L o S One. 14, 2, 12 p., e0211690.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breastfeeding duration in infancy and adult risks of type 2 diabetes in a high-income country
Bjerregaard, L. G., Pedersen, D. C., Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Maternal and Child Nutrition. 15, 4, 9 p., e12869.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training
Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Helgeland, O., Horikoshi, M., Karhunen, V., Lowry, E., Cousminer, D. L., Ahluwalia, T. S., Thiering, E., Boh, E. T-H., Zafarmand, M. H., Vilor-Tejedor, N., Wang, C. A., Joro, R., Chen, Z., Gauderman, W. J., Pitkanen, N., Parra, E. J. & 79 others, , 2019, In: Human Molecular Genetics. 28, 19, p. 3327-3338Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study
Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?
Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes
Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Polygenic predisposition to breast cancer and the risk of coronary artery disease
D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, Niels, Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity
Drivsholm, A., Lund, Morten Asp Vonsild, Hedley, P. L., Jespersen, Thomas, Christiansen, M., Hansen, Torben & Holm, Jens-Christian, 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 12, p. 1351-1358Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
Ehmann, D., Wendler, J., Koeninger, L., Larsen, I. S., Klag, T., Berger, J., Marette, A., Schaller, M., Stange, E. F., Malek, N. P., Jensen, Benjamin Anderschou Holbech & Wehkamp, J., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3746-3751Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes
pjx571, pjx571, Appel, V. E., Schnurr, T. M., Lundby-Christensen, L., Skaaby, T., Linneberg, Allan René, Drivsholm, Thomas, Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & drb459, drb459, 2019, In: Diabetes and Vascular Disease Research. 16, 1, p. 13-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haploinsufficiency of ARHGAP42 is associated with hypertension
Fjorder, A. S., Rasmussen, Malene Bøgehus, Mehrjouy, M. M., Nazaryan, Lusine, Hansen, C., Bak, M., Grarup, Niels, Nørremølle, Anne, Larsen, Lars Allan, drb459, drb459, Hansen, Torben, Tommerup, Niels & Bache, Iben, 2019, In: European Journal of Human Genetics. 27, 8, p. 1296-1303 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Broad Genomics Platform, B. G. P., Jun 2019, In: Nature. 570, 7759, p. 71-76 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose metabolism in children and adolescents: Population-based reference values and comparisons to children and adolescents enrolled in obesity treatment
Frithioff-Bøjsøe, C., Lund, Morten Asp Vonsild, Kloppenborg, J. T., Nielsen, T. T. H., Fonvig, Cilius Esmann, Lausten-Thomsen, U., Hedley, P. L., Hansen, T., Pedersen, Oluf Borbye, Christiansen, M., Baker, J. L., Hansen, Torben & Holm, Jens-Christian, 2019, In: Pediatric Diabetes. 20, 5, p. 538-548Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular Vesicle Encapsulated MicroRNAs in Patients with Type 2 Diabetes Are Affected by Metformin Treatment
Ghai, V., Kim, T., Etheridge, A., Nielsen, T., Hansen, Torben, Pedersen, Oluf Borbye, Galas, D. & Wang, K., 2019, In: Journal of Clinical Medicine. 8, 17 p., 617.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations
Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, , 2019, In: Diabetes. 68, 3, p. 502-514Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reference values for fasting serum concentrations of thyroid-stimulating hormone and thyroid hormones in healthy Danish/North-European white children and adolescents
Gunapalasingham, G., Frithioff-Bojsoe, C., Lund, Morten Asp Vonsild, Hedley, P. L., Fonvig, Cilius Esmann, Dahl, M., Pedersen, Oluf Borbye, Christiansen, M., Hansen, Torben, Lausten-Thomsen, U. & Holm, Jens-Christian, 2019, In: Scandinavian Journal of Clinical & Laboratory Investigation. 79, 1-2, p. 129-135Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis
Hartwig, F. P., Davies, N. M., Horta, B. L., Ahluwalia, T. S., Bisgaard, H., Bønnelykke, K., Caspi, A., Moffitt, T. E., Poulton, R., Sajjad, A., Tiemeier, H. W., Dalmau-Bueno, A., Guxens, M., Bustamante, M., Santa-Marina, L., Parker, N., Paus, T., Pausova, Z., Lauritzen, L., Schnurr, T. M. & 7 others, , 2019, In: International Journal of Epidemiology. 48, 1, p. 45-57 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study
Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J-F., Ahluwalia, T. V. S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T. O., Kleber, M. E. & 31 others, , 2019, In: JAMA Network Open. 2, 9, 18 p., e1910915.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies
Huang, T., Sun, D., Heianza, Y., Bergholdt, H. K. M., Gao, M., Fang, Z., Ding, M., Frazier-Wood, A. C., North, K. E., Marouli, E., Graff, M., Smith, C. E., Varbo, A., Lemaitre, R. N., Corella, D., Wang, C. A., Tjønneland, A., Overvad, K., Sørensen, T. I. A., Feitosa, M. F. & 36 others, , 2019, In: Clinical Chemistry. 65, 6, p. 751-760 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity and unfavourable lifestyle increase type 2 diabetes-risk independent of genetic predisposition
Jakupovic, Hermina, Schnurr, T. M., Carrasquilla, Germán D., Grarup, Niels, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: Diabetologia. 62, Suppl. 1, p. S188 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men
Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, , 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice
Kashani, A., Brejnrod, A. D., Jin, C., Kern, T., Madsen, A. N., Holm, L. A., Gerber, G. K., Holm, Jens-Christian, Hansen, Torben, Holst, Birgitte & Arumugam, Mani, 2019, In: Animal Microbiome. 1, 1, 16 p., 11.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining
Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, , 2019, In: eLife. 8, 19 p., e44941.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes
Kjaer, L. K., Cejvanovic, V., Henriksen, T., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, 3 Jun 2019, In: Free Radical Research. 53, 6, p. 694-703Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium
Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, , 2019, In: Diabetologia. 62, 9, p. 1601-1615Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits
Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, , 2019, In: American Journal of Human Genetics. 104, 1, p. 112-138 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice
Larsen, I. S., Fritzen, Andreas Mæchel, Carl, Christian Strini, Agerholm, M., Damgaard, Mads Vargas, Holm, J. B., Marette, A., Nordkild, P., Kiens, Bente, Kristiansen, Karsten, Wehkamp, J. & Jensen, Benjamin Anderschou Holbech, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 1, p. E42-E52 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FADS and PPARG2 single nucleotide polymorphisms are associated with plasma lipids in 9-mo-old infants
Lauritzen, Lotte, Amundsen, I. D., Damsgaard, Camilla Trab, Lind, M. V., Schnurr, T. M., Hansen, Torben, Michaelsen, Kim F. & Vogel, U., 2019, In: Journal of Nutrition. 149, 5, p. 708-715 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reference values for leptin/adiponectin ratio in healthy children and adolescents
Lausten-Thomsen, U., Lund, Morten Asp Vonsild, Frithioff-Bojsoe, C., Hedley, P. L., Pedersen, Oluf Borbye, Hansen, Torben, Christiansen, M. & Holm, Jens-Christian, 2019, In: Clinica Chimica Acta. 493, p. 123-128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures
Lundgren, J. R., Faerch, K., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Holst, Jens Juul, Vistisen, D., Jorgensen, M. E., Torekov, Signe Sørensen & Johansen, N. B., 2019, In: Cardiovascular Diabetology. 18, 1, 9 p., 130.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms preserving insulin action during high dietary fat intake
Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, K. A., Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, T. S., Hingst, J. R., Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity
Mascolo, E., Barile, A., Mecarelli, L. S., Amoroso, N., Merigliano, C., Massimi, A., Saggio, I., Hansen, Torben, Tramonti, A., Di Salvo, M. L., Barbetti, F., Contestabile, R. & Verni, F., 2019, In: Scientific Reports. 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood growth and risk of inflammatory bowel disease: a population-based study of 317,030 children
Mendall, M., Jensen, C. B., Ängquist, Lars, Baker, J. L. & Jess, T., 2019, In: Scandinavian Journal of Gastroenterology. 54, 7, p. 863-868Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
Dashti, H. S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Cohorts for Heart and Aging Research in Genetic Epidemiology Consortium, C. F. H. A. A. R. I. G. E. C., 2019, In: Molecular Psychiatry. 24, p. 1920–1932Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis
Merino, J., Guasch-Ferré, M., Ellervik, C., Dashti, H. S., Sharp, S. J., Wu, P., Overvad, K., Sarnowski, C., Kuokkanen, M., Lemaitre, R. N., Justice, A. E., Ericson, U., Braun, K. V. E., Mahendran, Y., Frazier-Wood, A. C., Sun, D., Chu, A. Y., Tanaka, T., Luan, J., Hong, J. & 48 others, , 2019, In: BMJ (Clinical research ed.). 366, p. l4292Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects
Middeldorp, C. M., Mahajan, A., Horikoshi, M., Robertson, N. R., Beaumont, R. N., Bradfield, J. P., Bustamante, M., Cousminer, D. L., Day, F. R., De Silva, N. M., Guxens, M., Mook-Kanamori, D. O., St Pourcain, B., Warrington, N. M., Adair, L. S., Ahlqvist, E., Ahluwalia, T. S., Almgren, P., Ang, W., Atalay, M. & 463 others, , 2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
Miguel-Escalada, I., Bonàs-Guarch, S., Cebola, I., Ponsa-Cobas, J., Mendieta-Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García-Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos-Rodríguez, M., Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., Pedersen, O. & 16 others, , 2019, In: Nature Genetics. 51, 7, p. 1137-1148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes
Niazi, R. K., Sun, J., Have, C. T., Hollensted, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Grarup, Niels, Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 1, p. 1-12 e0210114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report
Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Borisevich, D., Grarup, Niels, Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Shafqat, I., Gul, A. & Hansen, Torben, 2019, In: B M C Medical Genetics. 20, 8 p., 152.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
et al., E. A. & Warren, H. R., 25 Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3118-3131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reappraisal of variants previously linked with sudden infant death syndrome: results from three population-based cohorts
Paludan-Müller, Christian, Ghouse, Jonas, Vad, O. B., Herfelt, C. B., Lundegaard, Pia Rengtved, Ahlberg, G., Schmitt, Nicole, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2019, In: European Journal of Human Genetics. 27, 9, p. 1427-1435Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overweight Patterns Between Childhood and Early Adulthood and Esophageal and Gastric Cardia Adenocarcinoma Risk
Petrick, J. L., Jensen, B. W., Sørensen, Thorkild I.A., Cook, M. B. & Baker, J. L., 2019, In: Obesity. 27, 9, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smallpox and BCG vaccination in childhood and cutaneous malignant melanoma in Danish adults followed from 18 to 49 years
Rieckmann, Andreas, Meyle, K. D., Rod, Naja Hulvej, Baker, J. L., Benn, C. S., Aaby, P. & Sørup, S., 2019, In: Vaccine. 37, 44, p. 6730-6736 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
Roager, H. M., Vogt, J. K., Kristensen, M. B., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Hartmann, B. & 18 others, , Jan 2019, In: Gut. 68, 1, p. 83-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., Van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E. & 145 others, , 2019, In: BMC Cardiovascular Disorders. 19, 1, 10 p., 240.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The DynaHEALTH consortium - a European consortium for a life-course bio-psychosocial model of healthy ageing of glucose homeostasis
Sebert, S., Lowry, E., Aumuller, N., Bermudez, M. G., Bjerregaard, L. G., de Rooij, S. R., De Silva, M., El Marroun, H., Hummel, N., Juola, T., Mason, G., Much, D., Oliveros, E., Poupakis, S., Rautio, N., Schwarzfischer, P., Tzala, E., Uhl, O., van de Beek, C., Vehmeijer, F. & 23 others, , 2019, In: International Journal of Epidemiology. 48, 4, p. 1051-1051k 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between adult height and type 2 diabetes mellitus: a systematic review and meta-analysis of observational studies
Shrestha, S., Rasmussen, S. H., Pottegård, A., Ängquist, Lars, Jess, T., Allin, K. H., Bjerregaard, L. G. & Baker, J. L., 2019, In: Journal of Epidemiology & Community Health. 73, 7, p. 681-688Research output: Contribution to journal › Review › Research › peer-review
- Published
Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis
Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B. & 27 others, , 2019, In: Addiction. 114, 2, p. 216-225 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology: [incl. correction]
Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I. & 31 others, , 2019, In: American Journal of Human Genetics. 105, 1, p. 15-28 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Childhood Body-Mass Index and Risk of Venous Thromboembolism in Adulthood
Sundbøll, J., Ängquist, Lars, Adelborg, K., Gjærde, L. K., Ording, A., Sørensen, Thorkild I.A., Baker, J. L. & Sørensen, H. T., 2019, In: Journal of the American Heart Association. 8, 6, 20 p., e011407.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abdominal adiposity and cardiometabolic risk factors in children and adolescents: A Mendelian randomization analysis
Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Atalay, M., Lind, M. V., Heikkinen, S., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Carrasquilla, G. D., Larnkjær, A., Pedersen, O., Michaelsen, K. F., Lakka, T. A., Holm, J-C., Lehtimäki, T. & 3 others, , 2019, In: American Journal of Clinical Nutrition. 110, 5, p. 1079-1087 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents
Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Lintu, N., Lind, M. V., Atalay, M., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Larnkjær, A., Pedersen, O. B., Holm, J-C., Michaelsen, K. F., Lakka, T. A., Lehtimäki, T., Raitakari, O. & 2 others, , 2019, In: International Journal of Obesity. 43, p. 2007-2016 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, , 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits
van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikäinen, L-P., Mei, H., Müller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., Boomsma, D. I. & 41 others, , 2019, In: European Journal of Human Genetics. 27, p. 952-962Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Ängquist, Lars, Baker, J. L., Damsgaard, Camilla Trab, Eliasen, M., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A., Jørgensen, T., Tang Møllehave, L., Thuesen, B. H., Osler, Merete & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C., 2019, In: Nature. 569, 7755, p. 260-264 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2018
- Published
Aberrant intestinal microbiota in individuals with prediabetes
Allin, K. H., Tremaroli, V., Caesar, R., Jensen, Benjamin Anderschou Holbech, Damgaard, Mads Vargas, Bahl, M. I., Licht, T. R., Hansen, T. H., Nielsen, T., Dantoft, T. M., Linneberg, Allan René, Jørgensen, T., drb459, drb459, Kristiansen, Karsten, Franks, P. W., IMI-DIRECT consortium, I. C., Hansen, Torben, Bäckhed, G. F. & Pedersen, Oluf Borbye, Apr 2018, In: Diabetologia. 61, 4, p. 810-820 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of metabolic traits in Greenlanders: lessons from an isolated population
Lepola, Mette Andersen & Hansen, Torben, 2018, In: Journal of Internal Medicine. 284, 5, p. 464-477 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of obesity and related metabolic traits - recent insights from isolated populations
Lepola, Mette Andersen, Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2018, In: Current Opinion in Genetics and Development. 50, p. 74-78 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest
Andreasen, Laura Korsholm, Ghouse, J., Skov, M. W., Have, C. T., Ahlberg, G., Rasmussen, P. V., Linneberg, Allan René, Pedersen, Oluf Borbye, Platonov, P. G., Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2018, In: Frontiers in Physiology. 9, p. 1-9 894.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel, V. R., Moltke, Ida, Jørgensen, M. E., Bjerregaard, P., Linneberg, Allan René, Pedersen, Oluf Borbye, Albrechtsen, Anders, Hansen, Torben & Grarup, Niels, 2018, In: European Journal of Human Genetics. 26, 6, p. 868-875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Bihlmeyer, N. A., Brody, J. A., Smith, A. V., Warren, H. R., Lin, H., Isaacs, A., Liu, C-T., Marten, J., Radmanesh, F., Hall, L. M., Grarup, N., Mei, H., Muller-Nurasyid, M., Huffman, J. E., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., Weiss, S. & 30 others, , 2018, In: Circulation. Genomic and precision medicine. 11, 1, p. 1-10 e001758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Change in Overweight from Childhood to Early Adulthood and Risk of Type 2 Diabetes
Bjerregaard, L. G., Jensen, B. W., Ängquist, Lars, Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 2018, In: The New England Journal of Medicine. 378, 14, p. 1302-1312 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development, tracking, distribution and time trends in body weight during childhood
Bjerregaard, L. G., Baker, J. L. & Sørensen, Thorkild I.A., 2018, Eating Disorders and Obesity in Children and Adolescents. Hebebrand, J. & Herpertz-Dahlmann, B. (eds.). 1 ed. St. Louis, Missouri: Elsevier, p. 63-66 4 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, , 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial
Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: BMJ Open. 8, p. 1-9 e022517.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes
Cousminer, D. L., Ahlqvist, E., Mishra, R., Andersen, M. K., Chesi, A., Hawa, M. I., Davis, A., Hodge, K. M., Bradfield, J. P., Zhou, K., Guy, V. C., Akerlund, M., Wod, M., Fritsche, L. G., Vestergaard, H., Snyder, J., Højlund, K., Linneberg, A., Karajamaki, A., Brandslund, I. & 33 others, , 2018, In: Diabetes Care. 41, 11, p. 2396-2403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum
Crusell, Mie Korslund Wiinblad, Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, Peter, drb459, drb459, Rørbye, Christina, Jørgensen, N. R., Christiansen, O. B., Heinsen, F., Franke, A., Hansen, Torben, Lauenborg, J. & Pedersen, Oluf Borbye, 15 May 2018, In: Microbiome. 6, 19 p., 89.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth weight variants are associated with variable fetal intrauterine growth from 20 weeks of gestation
pjx571, pjx571, Gybel-brask, D., Mahendran, Y., Crusell, Mie Korslund Wiinblad, Hansen, T. H., Schnurr, T. M., Høgdall, Estrid Vilma Solyom, Skibsted, L., Hansen, Torben & drb459, drb459, 2018, In: Scientific Reports. 8, 11 p., 8376.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2449
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Estimation of allele frequency and association mapping using next-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection
Research output: Contribution to journal › Journal article › Research › peer-review
Genome-wide association study of preserved ratio impaired spirometry (PRISm)
Research output: Contribution to journal › Journal article › Research › peer-review
Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
Research output: Contribution to journal › Journal article › Research › peer-review