Hansen Group

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  1. 2022
  2. Published

    Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes

    O'Connor, M. J., Schroeder, P., Huerta-Chagoya, A., Cortés-Sánchez, P., Bonàs-Guarch, S., Guindo Martínez, Marta, Cole, J. B., Kaur, V., Torrents, D., Veerapen, K., Grarup, Niels, Kurki, M., Friis, Carsten, Pedersen, Oluf Borbye, Brandslund, I., Linneberg, Allan René, Hansen, Torben, Leong, A., Florez, J. C. & Mercader, J. M., 2022, In: Diabetes. 71, 3, p. 554–565

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, Freese, J., Herd, P., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., McCreight, J. C., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Pers, Tune H, Timshel, P., Ahluwalia, Tarun Veer Singh, Bønnelykke, Klaus, Bisgaard, H., Sørensen, Thorkild I.A., 23andMe Research Team, 2. R. T., Social Science Genetic Association Consortium, S. S. G. A. C. & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

    Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Association of general health and lifestyle factors with the salivary microbiota – Lessons learned from the ADDITION-PRO cohort

    Poulsen, C. S., Nygaard, Nikoline, Constancias, F., Stankevic, Evelina, Kern, T., Witte, D. R., Vistisen, D., Grarup, Niels, Pedersen, Oluf Borbye, Midjord-Belstrøm, Daniel & Hansen, Torben, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 15 p., 1055117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

    Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D. & 32 others, Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Zhao, J. H., Aadahl, Mette, Bork-Jensen, J., Møllehave, L. T., Liu, J., Wang, J., drb459, drb459, Jackson, R. D., Kovacs, P., Pedersen, Oluf Borbye, Hansen, Torben, Lind, L., Loos, Ruth, Christensen, K., Linneberg, Allan René, Grarup, Niels, Dantoft, T. M., Karpe, F., Wei, W. Q., Sun, Y. V., Million Veterans Program, M. V. P. & Global Lipids Genetics Consortium, G. L. G. C., 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Exome sequencing reveals the first intragenic deletion in ABCA5 underlying autosomal recessive hypertrichosis

    Raza, R., Ullah, A., Haider, N., Krishin, J., Shah, M., Khan, F. U., Abdullah, Hansen, Torben, Raza, S. I., Ahmad, W. & Basit, S., 2022, In: Clinical and Experimental Dermatology. 47, 6, p. 1137-1143

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Lipolysis defect in people with obesity who undergo metabolic surgery

    Rydén, M., Andersson, D. P., Kotopouli, M. I., Stenberg, E., Näslund, E., Thorell, A., Sørensen, Thorkild I.A. & Arner, P., 2022, In: Journal of Internal Medicine. 294, 4, p. 667-678 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD

    Schnurr, T. M., Katz, S. F., Justesen, Johanne Marie, O'Sullivan, J. W., Saliba-Gustafsson, P., Assimes, T. L., Carcamo-Orive, I., Ahmed, A., Ashley, E. A., Hansen, Torben & Knowles, J. W., 2022, In: Hepatology Communications. 6, 7, p. 1516-1526

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Smoking during pregnancy is associated with child overweight independent of maternal pre-pregnancy BMI and genetic predisposition to adiposity

    Schnurr, T. M., Ängquist, Lars, Nohr, E. A., Hansen, Torben, Sørensen, Thorkild I.A. & Morgen, C. S., 2022, In: Scientific Reports. 12, 1, 10 p., 3135.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Molecular Insights into the Role of Pathogenic nsSNPs in GRIN2B Gene Provoking Neurodevelopmental Disorders

    Shah, A. A., Amjad, M., Hassan, J. U., Ullah, A., Mahmood, A., Deng, H., Ali, Y., Gul, F. & Xia, K., 2022, In: Genes. 13, 8, 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Changing genetic architecture of body mass index from infancy to early adulthood: an individual based pooled analysis of 25 twin cohorts

    Silventoinen, K., Li, W., Jelenkovic, A., Sund, R., Yokoyama, Y., Aaltonen, S., Piirtola, M., Sugawara, M., Tanaka, M., Matsumoto, S., Baker, L. A., Tuvblad, C., Tynelius, P., Rasmussen, F., Craig, J. M., Saffery, R., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Martin, N. G. & 37 others, Medland, S. E., Montgomery, G. W., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Christensen, K., Skytthe, A., Kyvik, K. O., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Corley, R. P., Huibregtse, B. M., Knafo-Noam, A., Mankuta, D., Abramson, L., Haworth, C. M. A., Plomin, R., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Duncan, G. E., Buchwald, D., Burt, S. A., Klump, K. L., Llewellyn, C. H., Fisher, A., Boomsma, D., Sørensen, Thorkild I.A. & Kaprio, J., 2022, In: International Journal of Obesity. 46, p. 1901–1909 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts

    Silventoinen, K., Piirtola, M., Jelenkovic, A., Sund, R., Tarnoki, A. D., Tarnoki, D. L., Medda, E., Nisticò, L., Toccaceli, V., Honda, C., Inui, F., Tomizawa, R., Watanabe, M., Sakai, N., Gatz, M., Butler, D. A., Lee, J., Lee, S. J., Sung, J., Franz, C. E. & 31 others, Kremen, W. S., Lyons, M. J., Derom, C. A., Vlietinck, R. F., Loos, Ruth, Tynelius, P., Rasmussen, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Brandt, I., Nilsen, T. S., Harris, J. R., Tyler, J., Hopper, J. L., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Rebato, E., Zhang, D., Pang, Z., Tan, Q., Silberg, J. L., Maes, H. H., Boomsma, D. I., Sørensen, Thorkild I.A., Korhonen, T. & Kaprio, J., 2022, In: Scientific Reports. 12, 1, 9 p., 13148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Exome Sequencing Revealed a Novel Splice Site Variant in the CRB2 Gene Underlying Nephrotic Syndrome

    Simaab, A., Krishin, J., Alaradi, S. R., Haider, N., Shah, M., Ullah, A., Abdullah, A., Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Medicina. 58, 12, 9 p., 1784.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis

    Skaaby, T., Kilpeläinen, Tuomas O., Mahendran, Y., Huang, L. O., Sallis, H., Thuesen, B. H., Kårhus, L. L., Leth-Møller, K. B., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2022, In: European Journal of Epidemiology. 37, p. 713-722

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

    Solomon, O., Huen, K., Yousefi, P., Küpers, L. K., González, J. R., Suderman, M., Reese, S. E., Page, C. M., Gruzieva, O., Rzehak, P., Gao, L., Bakulski, K. M., Novoloaca, A., Allard, C., Pappa, I., Llambrich, M., Vives, M., Jima, D. D., Kvist, T., Baccarelli, A. & 65 others, White, C., Rezwan, F. I., Sharp, G. C., Tindula, G., Bergström, A., Grote, V., Dou, J. F., Isaevska, E., Magnus, M. C., Corpeleijn, E., Perron, P., Jaddoe, V. W. V., Nohr, E. A., Maitre, L., Foraster, M., Hoyo, C., Håberg, S. E., Lahti, J., DeMeo, D. L., Zhang, H., Karmaus, W., Kull, I., Koletzko, B., Feinberg, J. I., Gagliardi, L., Bouchard, L., Ramlau-Hansen, C. H., Tiemeier, H., Santorelli, G., Maguire, R. L., Czamara, D., Litonjua, A. A., Langhendries, J. P., Plusquin, M., Lepeule, J., Binder, E. B., Verduci, E., Dwyer, T., Carracedo, Á., Ferre, N., Eskenazi, B., Kogevinas, M., Nawrot, T. S., Munthe-Kaas, M. C., Herceg, Z., Relton, C., Melén, E., Gruszfeld, D., Breton, C., Fallin, M. D., Ghantous, A., Nystad, W., Heude, B., Snieder, H., Hivert, M. F., Felix, J. F., Sørensen, Thorkild I.A., Bustamante, M., Murphy, S. K., Raikkönen, K., Oken, E., Holloway, J. W., Arshad, S. H., London, S. J. & Holland, N., 2022, In: Mutation Research - Reviews in Mutation Research. 789, 108415.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Hyperglucagonemia in pediatric adiposity associates with cardiometabolic risk factors but not hyperglycemia

    Stinson, Sara, Jonsson, Anna Elisabet, Alzola, I. F. D. R., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Holm, L. A., Fonvig, Cilius Esmann, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 6, p. 1569–1576

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Do gene-environment interactions have implications for the precision prevention of type 2 diabetes?

    Sørensen, Thorkild I.A., Metz, Sophia & Kilpeläinen, Tuomas O., 2022, In: Diabetologia. 65, p. 1804–1813 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine

    Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  20. Published

    Binge drinking induces an acute burst of markers of hepatic fibrogenesis (PRO-C3)

    Torp, N., Israelsen, M., Nielsen, M. J., Åstrand, C. P., Juhl, P., Johansen, S., Hansen, C. D., Madsen, B., Villesen, I. F., Leeming, D. J., Thiele, M., Hansen, Torben, Karsdal, M. & Krag, A., 2022, In: Liver International. 42, 1, p. 92-101

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A novel nonsense variant in EXOC8 underlies a neurodevelopmental disorder

    Ullah, A., Krishin, J., Haider, N., Aurangzeb, B., Abdullah, Suleman, Sufyan, Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Neurogenetics. 23, p. 203-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Clinical and genetic characterization of patients segregating variants in KPTN, MINPP1, NGLY1, AP4B1, and SON underlying neurodevelopmental disorders: Genetic and phenotypic expansion

    Ullah, A., Shah, A. A., Alluqmani, M., Haider, N., Aman, H., Alfadhli, F., Almatrafi, A. M., Albalawi, A. M., Krishin, J., Ullah Khan, F., Anjam, B. A., Abdullah, Peña Lozano, Elionora, Samad, A., Ahmad, W., Hansen, Torben, Xia, K. & Basit, S., 2022, In: International Journal of Developmental Neuroscience. 82, 8, p. 788-804

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

    Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, Grant, S. F. A., Felix, J. F. & Jaddoe, V. W. V., 2022, In: BMC Medical Genomics. 15, 16 p., 124.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, Niels, Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

    Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, Thomas, Cecilia Engel, Banasik, Karina, Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., drb459, drb459, Hansen, Torben, Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Pedersen, Oluf Borbye, Brunak, Søren & IMI-DIRECT consortium, I. C., 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journal › Journal article › Research › peer-review

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